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    • γδ T Cell Cancer Immunotherapy

      • 1st Edition
      • October 17, 2024
      • Marta Barisa
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 7 6 6 1
      • eBook
        9 7 8 0 4 4 3 2 1 7 6 7 8
      γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation sets out and critically discusses the current clinical and relevant preclinical γδ T cell immunotherapy landscape.In five chapters, field experts discuss the challenges facing γδ T cell oncoimmunotherapy, propose solutions, and map next steps.Particular attention is given to summarizing our understanding of the complex, translationally relevant human γδ T cell biology, the evidence basis for designing γδ T cell combination trials and data-driven perspectives on what is known—and what isn’t—about γδ T cell therapeutic persistence. Various perspectives are provided on how issues of cytotoxic effector function, functional exhaustion, and cytokine addiction can be mitigated using gene engineering.A chapter is dedicated to the systematic review of all γδ T cell immunotherapy trials to date, and the cell therapy products that were used in these trials. The final chapter discusses allograft persistence-enhancem... techniques in the context of γδ T cell therapy, covering lymphodepleting chemotherapy and synthetic stealth engineering.γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation gives an updated and comprehensive insight into the current state of γδT cell immunotherapy, which is of interest to existing translational γδ T cell specialists, the proliferating range of academic scientists and commercial scientists entering the field, as well as clinicians who may encounter γδ T cell immunotherapy in the clinic, or are wishing to familiarize themselves with noncanonical lymphocyte immunotherapy.

    • A New Era in Alzheimer's Research

      • 1st Edition
      • October 17, 2024
      • Sandeep Kumar Singh + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 5 4 0 6
      • eBook
        9 7 8 0 4 4 3 1 5 5 3 9 0
      A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals.

    • Genome Editing for Neurodegenerative Diseases

      • 1st Edition
      • October 17, 2024
      • Sandeep Kumar Singh + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 8 2 6 0
      • eBook
        9 7 8 0 4 4 3 2 3 8 2 7 7
      Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.

    • Intelligent Biomedical Technologies and Applications for Healthcare 5.0

      • 1st Edition
      • Volume 16
      • October 17, 2024
      • Lalit Garg + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 0 3 8 8
      • eBook
        9 7 8 0 4 4 3 2 2 0 3 9 5
      Intelligent Biomedical Technologies and Applications for Healthcare 5.0, Volume Sixteen covers artificial health intelligence, biomedical image analysis, 5G, the Internet of Medical Things, intelligent healthcare systems, and extended health intelligence (EHI). This volume contains four sections. The focus of the first section is health data analytics and applications. The second section covers research on information exchange and knowledge sharing. The third section is on the Internet of Things (IoT) and the Internet of Everything (IoE)-based solutions. The final section focuses on the implementation, assessment, adoption, and management of healthcare informatics solutions.This new volume in the Advances in Ubiquitous Sensing Applications for Healthcare series focuses on innovative methods in the healthcare industry and will be useful for biomedical engineers, researchers, and students working in interdisciplinary fields of research. This volume bridges these newly developing technologies and the medical community in the rapidly developing healthcare world, introducing them to modern healthcare advances such as EHI and Smart Healthcare Systems.

    • Conductive Hydro Drying of Foods

      • 1st Edition
      • October 16, 2024
      • C. Anandharamakrishnan + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 5 6 0 2 4
      • eBook
        9 7 8 0 3 2 3 9 5 6 0 3 1
      Conductive Hydro Drying of Foods: Principles and Applications presents the current state of this emerging field, touching basics of novel drying approaches, introducing the concept of conductive hydro drying, and detailing its applications in food processing. The book explores novel drying techniques and covers the drying of various foods, including fruits and vegetables, meat, fish, poultry, and egg, spices and herbs, cereals and pulses, and other edible materials. It also brings chapters on trends and prospects, providing emphasis on the scope for low-cost drying, drying, or heat-sensitive foods. Edited by authors with interdisciplinary backgrounds and strong expertise in the field of food drying, this is a valuable resource to research and industry professionals working in allied fields.

    • Immunotoxicogenomics

      • 1st Edition
      • October 16, 2024
      • Md. Naimat Ali + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 5 0 2 1
      • eBook
        9 7 8 0 4 4 3 1 8 5 1 1 3
      Immunotoxicogenomics... A Multidisciplinary Approach in Systems Toxicology covers the major mechanisms and effects of toxic substances on the immune system, and on the regulation of gene expression. This includes the aims, opportunities, clinical applications, recent developments, and emerging and future trends. The book begins with a discussion of the systemic approach to toxicants, but also looks at current genomic tools used to assess immunotoxicity and systems biology methods used in immuno-toxicogenomic... Other topics include genomic expression profiling, gene expression as a tool to understand and predict immunotoxicity, immunotox-icogenomic... as a screening tool, and the assessment and analysis of Immunotoxicogenomics data.This book provides a collaborative, multidisciplinary approach for researchers in the fields of toxicology, genetics, immunology, and others engaged in the study on the effects of toxic substances on immune responses.

    • Deciding with Children in Pediatrics

      • 1st Edition
      • October 16, 2024
      • John Massie + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 3 2 3 5
      • eBook
        9 7 8 0 4 4 3 2 2 3 2 2 8
      Deciding with Children in Pediatrics: Children’s Participation in Healthcare Decision-making provides the ethical underpinning and offers practical strategies to foster meaningful participation of children in decisions affecting their healthcare. It will assist clinicians to bring forward the perspectives and values of the child, ensuring their preferences are incorporated into decision-making or appropriately justified when this is not possible. This is to both improve healthcare delivery and serve the best interests of children— now and as decision-makers in the future.This book reviews theories underpinning the concept of deciding with children and explores how pediatric decision-making is standardly managed. It then proposes a model for making healthcare decisions with children. A panel of experienced clinicians and ethicists demonstrate, via a series of case studies, how to promote children’s participation across a variety of clinical areas, child ages, and developmental stages. It concludes with a review of questions, concerns, and challenges. Deciding with Children in Pediatrics: Children’s Participation in Healthcare Decision-making helps bridge the gap between philosophy and practical clinical ethics and creates a frame of reference for children’s healthcare providers.

    • Protocols in Biochemistry and Clinical Biochemistry

      • 2nd Edition
      • October 16, 2024
      • Buddhi Prakash Jain + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 9 4 5 1
      • eBook
        9 7 8 0 4 4 3 1 3 9 4 6 8
      Protocols in Biochemistry and Clinical Biochemistry, second edition, offers clear, applied instruction in fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose, and cholesterol levels, among other diagnostics. Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods, and troubleshooting, all to support a range of study types and clinical diagnostics. This fully revised edition has been expanded and enriched to feature 100 protocols, as well as chapter key term definitions and worked examples. All-new protocols added to this edition include identification of lipids by TLC, lipid per oxidation measurement by thiobarbituric acid assays, determination of serum amylase, catalase activity assay, superoxide dismutase assay, qualitative analysis of plant secondary metabolites, qualitative analysis of photochemicals, quantitative estimation of secondary metabolites, estimation of chlorophyll contents, and starch determination, among others. Each protocol is written to help researchers and clinicians easily reproduce lab methods and ensure accurate test results.

    • Microbiology and Health Benefits of Traditional Alcoholic Beverages

      • 1st Edition
      • October 16, 2024
      • Jyoti Prakash Tamang
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 3 2 2 0
      • eBook
        9 7 8 0 4 4 3 1 3 3 2 3 7
      Microbiology and Health Benefits of Traditional Alcoholic Beverages is an interdisciplinary reference for students, researchers, and academics studying anthropology and food and beverage science, especially those with interest in fermentation. Fermented beverages and alcoholic drinks are culturally and socially accepted products for consumption, drinking, entertainment, as well as for customary practices and religious purposes. Due to variation in substrates, climatic conditions, geographical locations and ethnicity, a colossal diversity of microbial community as well as major domains have been reported in the different varieties of fermented beverages of the world.This book covers the cultural context of these beverages along with their biochemistry, health benefits, and therapeutic uses. Topics include winemaking, malting and brewing of wine and beer, and culturally specific beverages and practices such as fermented palm beverages and agave.

    • Artificial Intelligence in Urology

      • 1st Edition
      • October 15, 2024
      • Andrew J Hung
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 1 3 2 3
      • eBook
        9 7 8 0 4 4 3 2 2 1 3 1 6
      Artificial Intelligence in Urology: Present and Future summarizes the cutting-edge development and adoption of Artificial Intelligence (AI) technologies in urology. The book explores barriers that prevent the further adoption of AI technologies, provides ethical considerations, and investigates the future role AI is expected to play. In addition, it includes applications of AI technology in the diagnosis and treatment of cancers (prostate, bladder, and more) and kidney stones, and in both adult and pediatric care. This is the perfect reference for researchers developing AI technologies for clinical applications and for clinicians who aim to effectively adopt AI technologies to solve clinical questions.

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