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Academic Press

  • Role of Sex and Gender in Aging and Longevity

    • 1st Edition
    • Calogero Caruso
    • English
    Role of Sex and Gender in Aging and Longevity aims to shed light on the complex interplay between sex and gender differences in the aging process and longevity of individuals. While biological sex differences have long been recognized as influencing various aspects of aging, this book includes how gender also plays a significant role in shaping these processes, accelerating aging, or favoring longevity. By acknowledging the influence of both biological and socially constructed factors, this book offers a comprehensive understanding of why individuals may experience different aging trajectories and have divergent longevity outcomes. This book explores the intricate ways in which gender norms, roles, and expectations shape individual experiences of aging and delves into the social determinants of health that can interact with biological factors to influence the aging process and longevity outcomes. By examining these interactions, this book aims to provide a nuanced understanding of the multifaceted nature of aging and longevity and how sex and gender contribute to these complex phenomena, laying the groundwork for future aging research and providing significant implications for disease prevention, screening, diagnosis, and treatment of age-related conditions.

  • Genomics-Guided Natural Products Discovery

    • 1st Edition
    • Volume 717
    • English
    Genomics-Guided Natural Products Discovery, Volume 717 focuses on how the genomics revolution has catalyzed a resurgence of interest in natural products research. With the explosion of new sequencing data to analyze, “genome-mining” tools have grown in sophistication. Hence, this volume captures the utility of these tools, serving as a how-to guide to lower the entry barrier for newcomers. Topics covered in this new release include Merging RODEO with genomic enzymology workflows to guide RiPP discovery, Exploring Ribosomally Synthesized and Post-translationally Modified Peptides through SPECO-Based Genome Mining, Genome Mining for Natural Products Made by Multinuclear Iron-dependent Oxidation Enzymes (MNIOs), and much more.Additional sections explore Genome-based discovery of polyketides generated by trans-acyltransferas... polyketide synthases, Global genome mining in fungi using FunBGCe, Plant genome mining of burpitides from fused precursor peptides, Determining biosynthetic gene cluster boundaries thru comparative bioinformatics, Genome mining for bacterial terpenoids, Bioinformatics guided synthesis of natural product cyclic peptides, Overview of Genome Mining Strategies for Natural Products Discovery, and much more.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 127
    • English
    Advances in Clinical Chemistry, Volume 127 explores physiologic and pathophysiologic biochemistry in both general and clinical chemistry. Complex molecular pathways are elucidated using historical, current, and emerging technologies such as biosensor design, metabolomics, and proteomics. Chapters in this new release include The Cancer Microbiome, Metabolomics of Nephrotic Syndrome, Advances in Biomimetic Sensor Technology, Gel electrophoresis-base... proteoform separation and analysis, Advances in blood microsampling technology for cancer biomarker detection, and MDDB: A public databank of host microRNAs in Tuberculosis diagnosis.

  • Environmental Pollution and Cardiovascular Diseases

    • 1st Edition
    • Sultan Ayoub Meo
    • English
    Environmental Pollution and Cardiovascular Diseases helps stakeholders enhance their knowledge about environmental pollution, weather conditions, climate change, and impacts on the cardiovascular system. The book further aims to ameliorate the global burden of cardiovascular deaths attributable to pollution by identifying trends in pollution-linked cardiovascular disease from the 1990s to present day. Overall, air pollution is estimated to cause about 34% of ischemic heart disease deaths. As these figures show no sign of declining, this book is a must-have for researchers, cardiologists, and others seeking to understand such an important etiological factor in so many cardiovascular illnesses.

  • Autoimmune Hemolytic Anemias

    A Practical Guide
    • 1st Edition
    • Wilma Barcellini + 1 more
    • English
    Autoimmune Hemolytic Anemias: A Practical Guide is a comprehensive update of autoimmune hemolytic anemias, a rare disease that is sometimes difficult to diagnose and manage. This book describes diagnosis, pathogenesis, classification, standard therapy, new treatments, as well as secondary forms, such as lymphoproliferative, immunodeficiency, Evans, and other autoimmune diseases. It is a practical guide to manage transfusions and monitoring complications, such as infections and thromboses, and preventive measures. This book is useful to researchers, clinicians, doctors and students working in hematology, transfusion centers, immunohematology labs, and internal medicine.

  • Advanced Topics in Inverse Data Envelopment Analysis

    Approaches for Handling Ratio Data
    • 1st Edition
    • Mehdi Soltanifar + 3 more
    • English
    Advanced Topics in Inverse Data Envelopment Analysis: Approaches for Handling Ratio Data explores and tackles the most significant challenges encountered by researchers and practitioners in decision analysis and performance evaluation. This book delves into the sophisticated realm of Ratio Data Envelopment Analysis (DEA-R), offering a thorough examination of advanced methodologies, practical examples, and insights into managing complex problems involving both non-negative and negative data. Filling crucial gaps in existing literature, this comprehensive resource focuses on the emerging field of Inverse DEA-R, equipping readers with the necessary tools and knowledge to address a wide range of challenging data types. This book serves as an essential guide for making informed and efficient decisions, guiding researchers and graduate students in computer science, applied mathematics, industrial engineering, and finance, navigating the complexities of decision analysis in today's data-driven world.

  • Cryo-electron Tomography

    A Journey From Sample Preparation to Data Mining
    • 1st Edition
    • Dorit Hanein + 1 more
    • English
    Cryo-Electron Tomography: A Journey from Sample Preparation to Data Mining providing a holistic overview of this rapidly advancing field and equipping researchers with the knowledge and tools necessary to initiate their own investigations. The book begins with a section on advanced cryogenic sample preparation for in situ cellular tomography, covering a range of sample types including viruses, bacteria, eukaryotic cells, and perspectives for organoids and tissues. Specific chapters focus on essential approaches such as vitrification, sample thinning, and bimodal correlative techniques. The book then transitions to a section on data mining and validation.

  • Narcolepsy

    Integrating Basic and Clinical Knowledge
    • 1st Edition
    • Ahmed S. BaHammam + 2 more
    • English
    Narcolepsy: Integrating Basic and Clinical Knowledge provides comprehensive coverage of narcolepsy-related topics. The book offers updated, deep coverage of its diagnosis, treatment, and impact on mental health based on the latest research findings and clinical practices. Its interdisciplinary approach brings together experts from different specialties, such as sleep medicine, psychology, and neurology to offer a more holistic understanding. This allows for a more nuanced discussion of how narcolepsy interacts with various aspects of health and well-being. Researchers and clinicians will find within this book novel information on pathophysiology and neurobiology, as well as behavioral and psychosocial considerations.Users will find this to be a resource that takes a deep dive into narcolepsy, introducing topics never before discussed in books on the topic, including COVID-19 and sleep, as well as immunotherapy and gene therapy. It’s the cutting-edge medical volume professionals need, whether narcolepsy specialists or more casual readers.

  • Handbook of Proteolytic Enzymes

    Metallopeptidases
    • 4th Edition
    • Neil D. Rawlings + 1 more
    • English
    Handbook of Proteolytic Enzymes, Metallopeptidases has stood as most comprehensive work in the field of applied enzymology and biocatalysis since the first edition published in 1998. Extensively revised and updated, the new fourth edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. Edited by world-renowned experts in the field, and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.This volume includes over 300 chapters on known metallopeptidases enzymes, including their name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with 2D structures of peptidases in color, extensive references, and links to PubMed and MEROPS databases.

  • Power Converters for Extraction and Conversion of Solar Photovoltaic Energy

    • 1st Edition
    • Sachin Jain + 2 more
    • English
    Renewable energy alternatives are fast becoming viable options to battle conventional fossil fuel shortcomings such as pollution, cost, and limited reserves. Understanding the requirements and source characteristics for successful power electronics and their application is pivotal to extracting power successfully.Power Converters for Extraction and Conversion of Solar Photovoltaic Energy provides a detailed analysis of the various power converter operations fed by solar PV energies. Practical aspects addressing the behavior of systems such as the operating point on source characteristics and when power converters buck or boost are considered as well, and are fundamental to effective use and applications of renewables.With computer simulation models for typical systems to give the reader a deeper insight and “feel” for the actual system, this book provides readers with a useable tool to develop and design their own systems and achieve successful power extraction.

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