Limited Offer
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Systems Biology and In-Depth Applications for Unlocking Diseases
Principles, Tools, and Application to Disease
- 1st Edition - December 1, 2024
- Editor: Babak Sokouti
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 2 3 2 6 - 6
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 2 3 2 7 - 3
Systems Biology and In-Depth Applications for Unlocking Diseases: Principles, tools and Application to Disease provides the essence of systems biology approaches in a practical… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteSystems Biology and In-Depth Applications for Unlocking Diseases: Principles, tools and Application to Disease provides the essence of systems biology approaches in a practical manner, illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment. Sections provide an introduction and history of systems biology, discuss the tools and resources needed for structure and function of biological systems, and present evidence of systems biology in action. Examples include big data techniques, scale networks, mathematical model development, and much more.
This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians.
- Provides detailed and comprehensive coverage of the field of systems biology
- Delivers instruction on how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment
- Makes effective steps towards personalized medicine in the treatment of disease
- Explains effective disease treatment strategies at early diagnosis stages
Systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians, Pharmaceutical industries, biotechnologists
Part 1. Introduction
1.1 Systems biology at a glance
1.2. A history on systems biology evolution
1.3. Brief information on cellular biology and signaling pathways
1.4. Systems biology: where are we?
1.5. Filling the gaps between systems biology and cell biology
1.6 Concluding remarks
1.7 Mathematical concepts
1.5. Kinetic and dynamics of biological systems
Part 2. Tools and Resources
2.1. Biological data sources
2.1.1. Microarray
2.1.2. Next generation sequencing (NGS)
2.1.3. Comparative genomic hybridization (CGH)
2.1.4. Single nucleotide polymorphisms (SNP)
2.2. High throughput data
2.1.2. Databases
2.3. Programming, tools and software
Part 3. Systems biology in action – to understand diseases
3.1 Big data analysis techniques
3.2 Reconstruction of genome and proteomic scale network structures and functions
3.3 Validation strategies
3.3.1 Mathematical model development
3.3.2 Biological gene expression models
3.3.3 Experimental techniques
3.4 Applications of systems biology extensions in diseases
3.4.1 Systems immunology
3.4.2 Systems pharmacology
3.4.3 Systems virology
3.4.4 Systems vaccinology
3.4.5 Systems neuroscience
3.4.6 Systems medicine
3.4.7 Future directions on systems biology
- No. of pages: 300
- Language: English
- Edition: 1
- Published: December 1, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443223266
- eBook ISBN: 9780443223273
BS
Babak Sokouti
Dr. Sokouti is an Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences. This is his third edited book, and he has authored multiple book chapters and journal articles.
Affiliations and expertise
Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences, Iran