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Elsevier

Academic Press

  • Nanodiagnostics to Identify and Detect Microbial Infections and Antimicrobial Resistance

    Volume 1 - Nanotheranostics, Microbial Infections, and Antimicrobial Resistance
    • 1st Edition
    • Divakar Sharma + 1 more
    • English
    Nanodiagnostics to Identify and Detect Microbial Infections and Antimicrobial Resistance: Volume One, Nanotheranostics, Microbial Infections, and Antimicrobial Resistance offers a comprehensive understanding of the global problem of antimicrobial resistance (AMR) and provides insights into the various aspects of AMR and how nanodiagnostics can be utilized to combat it. This volume discusses the development of nanotechnologies for detecting and diagnosing microbial resistant pathogens and explores a range of nano-inspired diagnostics, including biosensors, microfluidic-assiste... devices, nanorobotics, and nanocapsules.This book encompasses contributions from experts in the field, making it a valuable resource for researchers, academics, graduate students, industry professionals, and clinicians in microbiology, nanotechnology, and infectious diseases. It aids in early detection and identification of antimicrobial resistance, offering innovative solutions to combat this global challenge.

  • Imaging Blood-Brain Barrier Dysfunction in Brain Disorders

    • 1st Edition
    • Danny J.J. Wang + 1 more
    • English
    Imaging Blood-Brain Barrier Dysfunction in Brain Disorders delves into the intricate structure and function of the blood-brain barrier (BBB), examining its essential role in the pathogenesis of various brain disorders. The book offers a comprehensive overview of cutting-edge medical imaging technologies for visualizing BBB function, both in a healthy state and under diseased conditions. Readers will gain an in-depth understanding of how the BBB influences normal brain function, including aspects such as aging and sleep, and how its dysfunction is linked to serious neurological conditions.Furthermo... the book explores BBB anomalies in brain disorders like stroke, traumatic brain injury, cerebral small vessel disease, Alzheimer's disease, and sleep apnea. It highlights modern medical imaging technologies, such as MRI, for observing BBB function in vivo. It emphasizes the importance of BBB imaging for monitoring and potentially curing brain disorders, and discusses its potential in the early detection of neurological disorders, allowing for timely and effective treatment strategies.

  • Handbook on the Physics and Chemistry of Rare Earths

    Including Actinides
    • 1st Edition
    • Volume 68
    • English
    Handbook on the Physics and Chemistry of Rare Earths: Including Actinides, Volume 68 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Bacterial Efflux Systems

    • 1st Edition
    • Volume 724
    • English
    Bacterial Efflux Systems, Volume 722 covers experimental and computational approaches to study the function, structure, and mechanism of bacterial efflux pump systems. The methods covered include preparation of samples for structural and functional analyses and in vivo activity analysis. Specific chapters in this release cover Efflux pump functional assays, NMR and functional analysis efflux pumps, Methods for saturation mutagenesis and functional characterization, Cooperation and functional interplay between pumps, Mapping interactions, HDX-MS, and much more.Other sections cover Recombinant Expression and purification, Reconstitution of a RND efflux pump in different artificial membranes for a structural biology approach, Reconstitution of rnd and mfs efflux pumps for structural biology, CusCBA system, Expression and purification of efflux pumps of Gram positives, Expression and purification of efflux pumps of archaea, ABC transporters: BmrA preparation for NMR and PatA/PatB in peptidisc, In situ structural analysis of efflux assemblies by cryoET, Molecular dynamics simulations, and so much more.

  • Novel Bioproducts through Metabolic Engineering of Secondary Metabolites

    • 1st Edition
    • Yogesh K. Ahlawat + 3 more
    • English
    Novel Bioproducts through Metabolic Engineering of Secondary Metabolites provides comprehensive coverage of the latest developments in metabolic engineering and secondary metabolites, along with their roles in industrial product development. Sections cover the pivotal role secondary metabolites play in nature, their diverse classes, their significant applications in industry and medicine, and the fundamentals of metabolic engineering. Additional coverage includes biosynthetic pathways of secondary metabolites, strain development and optimization, rational design of pathway modifications, industrial enzymes and chemicals from metabolic engineering, and cutting-edge tools and technologies in metabolic engineering. The book concludes with a roadmap for the future of metabolic engineering, exploring emerging trends such as CRISPR and genome editing, artificial intelligence applications, and the evolving landscape of synthetic biology and bioeconomy.

  • Functionalized Drug Delivery Systems

    • 1st Edition
    • Umesh Gupta + 1 more
    • English
    Functionalized Drug Delivery Systems delves into the potential of various functionalized drug delivery systems, such as polymeric micelles, dendrimers, metallic nanoparticles, and SMEDDS. It offers a comprehensive guide from basic concepts to advanced surface engineering techniques. The book covers liposomes, dendrimers, metal nanoparticles, polymeric micelles, niosomes, and ethosomes, concluding with a chapter on the regulatory framework. This invaluable resource is perfect for pharmaceutical researchers and graduate students keen on advancing their understanding and application of these innovative drug delivery methods. The book also provides consolidated literature reviews, making it a foundational text for new researchers.Its chapters are dedicated to specific techniques, offering detailed insights into each method. Readers will gain knowledge on improving drug absorption and targeted delivery, supported by practical examples and case studies. The final chapter on regulatory frameworks ensures compliance and best practices in developing functionalized drug delivery systems. This book is an essential read for anyone in the field of pharmaceutical research.

  • Generative Artificial Intelligence and Creativity

    Precautions, perspectives, and possibilities
    • 1st Edition
    • Matthew J. Worwood + 1 more
    • English
    GENERATIVE ARTIFICIAL INTELLIGENCE AND CREATIVITY: PRECAUTIONS, PERSPECTIVES,AND POSSIBILITIES explores the dynamic relationship between generativeArtificial Intelligence (genAI) and creativity. This book brings together globalscholars from diverse fields to explore the transformative impact of genAI on humancreativity. As technological advancements in genAI continue to accelerate, this booknavigates through the complexities of understanding and harnessing its potential. GenerativeArtificial Intelligence and Creativity not only dissects the fundamental principlesunderlying genAI’s contribution to creativity but also addresses the paradoxical impactof genAI on human creative industries. This book serves as a unique guide for anyoneseeking to comprehend the implications of genAI on the future of human creativity.

  • Stabilization of Uncertain Fractional-Order Neutral-Type Delay Systems

    • 1st Edition
    • Alireza Alfi + 2 more
    • English
    Stabilization of Uncertain Fractional-Order Neutral-Type Delay Systems focuses on stabilizing uncertain fractional-order (FO) neutral-type (FONT) systems, addressing challenges like control input saturation and actuator delay. Beginning with a comprehensive introduction, the book progresses from constant fractional-order FONT (CFONT) systems to variable fractional-order FONT (VFONT) systems. It explores non-optimal and sub-optimal control techniques, such as guaranteed cost controllers (GCC), offering closed-loop stability and performance. Stabilization conditions are presented as linear matrix inequalities (LMIs), facilitating easy resolution with available toolboxes like MATLAB's LMI toolbox, or free software such as SEDUMI and YALMIP. In addition, the book investigates both state- and output-feedback controller structures. While most literature focuses on state-feedback control, the book acknowledges the limitations of accessing all system states and explores output-feedback control as an alternative. Both static and dynamic feedback controller types are studied, with dynamic feedback controllers offering improved transient response at the expense of increased complexity.

  • Phytochemicals and Gut Health

    Evidence and Opportunities for Gastrointestinal Management
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Phytochemicals and Gut Health: Evidence and Opportunities for Gastrointestinal Management highlights specific plant phytochemicals, their bioactive compounds, and the influence they have on the gut-brain axis. By exploring sources, production, mechanisms of action, and clinical applications, the book uncovers how certain bioactives can optimize health and improve gastrointestinal diseases while reducing the side effects and limited efficacy of current medical treatments. The book's authors identify different classes of plant-based phytochemicals such as phenolic metabolites, alkaloids, terpenoids, and glucosinolates while demonstrating a better understanding of the gut-nutraceutical axis that can improve microbiota for GI disorders, and more. Readers will also gain important perspectives on mechanisms of action and the synergistic effects phytochemicals have on cardiovascular and neurological health.

  • The Control of Multiple Unmanned Aerial Vehicles

    Synthesis, Functionalization to Applications
    • 1st Edition
    • Mingyang Xie + 2 more
    • English
    The Control of Multiple Unmanned Aerial Vehicles: Synthesis, Functionalization to Applications provides readers with a unified framework to address the challenges of multi-UAV target encirclement tracking control. This is achieved by comprehensively integrating the concepts of dynamic modelling, state and disturbance estimation, guidance law design, distributed control, obstacle avoidance and reinforcement learning-based formation tracking control with multi-UAV encirclement tracking systems. The book provides practical insight and solutions to the challenges of multi-UAV use, including limited sensing, communication constraint, wind disturbances and obstacle and collision avoidance, enabling readers to effectively apply the concepts to their work or research. Cutting-edge control techniques and advanced theories are explored, including robust distributed control, adaptive neural network approximation, reinforcement learning and multi-agent systems, presenting readers with state-of-the-art methodologies from which to develop practical applications of UAV formation. Each guidance and control method presented in the book is accompanied by a thorough comprehensive analysis to ensure that each is theoretically grounded. The book ensures transparency by providing open-access simulation codes, allowing readers to easily access and reproduce presented results.

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