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Elsevier

Academic Press

  • Enzymes of Polyamine Metabolism

    • 1st Edition
    • Volume 715
    • English
    Enzymes of Polyamine Metabolism, Volume 715 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Convergence of MYC and the hypusine circuits in the control of metabolism, HDAC10 structure and enzymology, TR-FRET Assay for Profiling HDAC10 Inhibitors and PROTACs, Polyamine Transport Inhibitors: Methods and caveats associated with measuring polyamine uptake in mammalian cells, Evaluation of platinum drug toxicity resulting from polyamine catabolism, Measurements of acrolein adducts resulting from polyamine catabolism, Alterations in polyamine metabolism induced by the pathogen Helicobacter pylori: implications for gastric inflammation and carcinogenesis, and much more.Other sections delve into Molecular and biochemical analysis of eIF5A, Analysis of in vivo SMOX activity, Structure and role of ATP13A2 in polyamine transport, Analysis of Translational Regulation Using Polysome Profiling and Puromycin Incorporation, Targeting polyamine metabolism in an ex vivo prostatectomy model, Development and characterization of a Drosophila model of SRS, Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples, Gene replacement therapy to restore polyamine metabolism, Investigation of polyamine metabolism in bone homeostasis, Collection, preparation, and biobanking of clinical specimens for polyamine analysis, and many other topics.

  • Biochemical Aspects of Metabolic Disorders

    • 1st Edition
    • Muhammad Sajid Hamid Akash + 1 more
    • English
    Biochemical Aspects of Metabolic Disorders offers a comprehensive exploration of the intricate biochemical mechanisms and/or pathways underlying a wide array of metabolic disorders. From the genetic basis of inherited metabolic conditions to the environmental factors impacting metabolic dysregulation, each chapter investigates the molecular insights essential for understanding and managing these complex diseases. Covering topics such as carbohydrate and lipid metabolism disorders, amino acid catabolism, hepatic and renal metabolism, mitochondrial dysfunction, pediatric obesity, and diagnostic approaches, this book will serve as a requisite resource for researchers, clinicians, and students alike looking for unravel the biochemical intricacies of metabolic disorders.

  • Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity

    • 1st Edition
    • Volume 121
    • English
    Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity, Volume 121 highlights new advances, with this new volume presenting interesting chapters on highly important topics such as Molecular virulence determinants of human-pathogenic filoviruses, Mucosal Sudan virus infection results in a lethal disease in ferrets with previous Lloviu virus infection not providing cross-protection, Transcriptional signatures of Ebola and Marburg virus infection in a Bat-Immune-System (BIS) mouse model, Divergences in the microbial inactivation pattern between vaporized hydrogen peroxide and aerosolized peracetic acid by dry fogging, and much more.Other chapters cover Molecular expressions in tissues and blood following Reston and Bundibugyo virus infection in swine, De novo rescue of new BSL4 henipaviruses - from sequence to pathogen, Semi-automated diagnostic RT-PCR as a screening assay for antiviral compounds in a 96-well format against highly pathogenic RNA viruses, and Relevance of studying virus – natural reservoir interactions: SNV in deer mice and LASV in Mastomys natalensis.

  • Culinary Nutrition

    The Science and Practice of Healthy Cooking
    • 2nd Edition
    • Jacqueline B. Marcus
    • English
    Culinary Nutrition: The Science and Practice of Healthy Cooking, Second Edition is one of the first textbooks specifically written to bridge the relationship between food science, nutrition, and culinology as well as consumer choices for diet, health, and enjoyment. The book uses a comprehensive format with real-life applications, recipes, and color photographs of finished dishes to emphasize the necessity of sustainably deliverable, health-beneficial, and taste-desirable products.The book includes pedagogical elements to enhance and reinforce learning opportunities; explores which foods and beverages involve the optimum nutritional values for dietary and health needs; includes specific dietary requirements throughout the lifecycle; and examines how foods and beverages are produced. The fully revised second edition includes updated dietary and health guidelines and recommendations; more vegan, vegetarian, and plant-based meals; updated protein, carbohydrate, fat, vitamin and mineral recommendations; environmental and sustainability considerations; and much more.

  • Biocatalysis

    • 1st Edition
    • Volume 714
    • English
    Biocatalysis, Volume 714 provides a wide range of themes dealing with the identification and application of biocatalysts. This includes various formats such as whole-cell or cell-free biocatalysis as well as immobilized variants. Specific chapters in this new release include Biocatalysis: How to select the proper mode of application, Documentation in biocatalysis and data handling, Mining metagenomes from extremophiles as resource for novel glycoside hydrolases for industrial applications, Functional Metaproteomics, Sequence-function relation for the prediction of enzyme properties: A case study on flavin-dependent oxidases, P450 monooxygenase in whole-cell format, and more.Additional sections cover Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells, Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species, C.necator as a model organism for CO2-based biotechnology, Cupriavidus in whole-cell biocatalysis, Whole-cell biocatalysis with Myxobacteria, Streptomyces for natural product formation: Targeted mutagenesis in PKS, Reductive Amination: Methods for cell-free and whole-cell biocatalysis, Challenges and good practices on transaminase-catalys... synthesis of optically pure amines, W-enzymes in biocatalysis: Chances and difficulties for the user, Atroposelective biocatalysis employing ADHs, Applications of alcohol oxidases, and much more.

  • Veterinary Toxicology

    Basic and Clinical Principles
    • 4th Edition
    • Ramesh C. Gupta
    • English
    Veterinary Toxicology: Basic and Clinical Principles, Fourth Edition is a unique single reference that provides a comprehensive overview on the basic principles of veterinary toxicology to any student at the DVM, MS, or PhD level while also continuing to serve as a clinical reference for practitioners. The book thoroughly updates toxicologists and advanced students on the newest approaches for diagnosing poisoning cases in all animals from chemicals, plants, and accidental or malicious intents. Many chapters are provided on topics not covered in any previous books, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.Completel... revised and updated to include the most recent developments in the field animal toxins, toxicokinetics mechanism of action, toxicity, and treatment, this book is an essential resource for researchers, practicing veterinary toxicologists, advanced students in toxicology, poison control centers, as well as environmentalists, marine biologists, and animal scientists.

  • Edge Intelligence in Cyber-Physical Systems

    Foundations and Applications
    • 1st Edition
    • Wei Yu
    • English
    Edge Intelligence in Cyber-Physical Systems: Foundations and Applications provides a comprehensive overview of best practices for building edge intelligence into cyber-physical systems. This book covers the foundations and applications of synergizing machine learning at the edge of CPS, leveraging an edge computing infrastructure. Divided into four parts, the first section of the book reviews the foundations, principles, and representative application domains of CPS. The second part covers machine learning, edge computing, and their needs in CPS, defining edge intelligence and its principles, challenges, and research directions. The third part presents tutorials and foundational research works on realizing edge intelligence in representative CPS. The fourth part explores the problem space of threats and countermeasures in building edge intelligence into CPS. Researchers, graduate students and professionals in computer science, data science, and electrical engineering will find this to be a valuable resource on the principles and applications of edge intelligence in cyber-physical systems as well as the development of interdisciplinary techniques to advance the field.

  • Handbook of Milk Production, Quality and Nutrition

    • 1st Edition
    • Tanmoy Rana
    • English
    Handbook of Milk Production, Quality and Nutrition emphasizes new applications to promote healthy milk production, processing, and product development in the milk industry, highlighting the role clean milk has in the prevention of health and disease. Sections cover the general aspects of milk production and its environmental impact on animal health, explain milk’s global nutritional appeal and its role as a source of both macro and micronutrients for human health, address issues of lactose intolerance and how this ailment is perceived globally, and discuss milk’s relevance on bone, ocular, and gut health.Finally, the book brings awareness to milk’s microbial pathogens, toxins, and heavy metals, and health concerns, while also updating on regulatory health and nutrition claims and recent legislative developments.

  • Clinical Pathophysiology of Hypertension, Diabetes, and Other Stress and Lifestyle Associated Diseases

    • 1st Edition
    • Tetsuya Watanabe
    • English
    Clinical Pathophysiology of Hypertension, Diabetes, and Other Stress and Lifestyle Associated Diseases presents mathematical and physical basis to apply in practice for a better understanding of some common and not so common diseases brough on by stress and lifestyle. Chapters cover new findings in hypertension, arrhythmias, diabetes, nephropathy, and periodontal disease. Written by Dr. Tetsuya Watanabe, President of Watanabe Institute of Mathematical Biology and Watanabe Clinic of Oral Surgery in Hamamatsu, Japan, for clinical doctors, medical research doctors, pathophysiological scientists, pharmaceutical scientists, and biologists and physicists in bioengineering.

  • Introduction to Digital Human Modeling

    • 1st Edition
    • Yujiang Xiang + 1 more
    • English
    Introduction to Digital Human Modeling bridges the gap in current literature by providing a comprehensive resource on digital human modeling for beginners and researchers. The content includes step-by-step procedures for building a digital human model, fundamental human kinematics and dynamics, advanced topics such as motion prediction and injury prevention, and industrial applications. The book covers theoretical concepts and experimental validation, including human anatomy, degrees of freedom, skeletal and musculoskeletal modeling, equations of motion, reach envelopes, lifting prediction, muscle fatigue model, and injury analysis. It teaches readers how to build simulation-based human models, set up equations of motion, analyze human biomechanics, and utilize simulations and experiments to study worker injuries. Furthermore, the book introduces both fundamental and advanced digital human modeling methods and optimization techniques aimed at improving performance and preventing injuries in manual material handling, as well as addressing lifting and gait biomechanics and ergonomics.

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