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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Alkaloids: Chemical and Biological Perspectives

    • 1st Edition
    • Volume 12
    • S.W. Pelletier
    • English
    Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, Acronychia baueri Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties.Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews. In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria. Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids. The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures. Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work. Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided.

  • Advances in Gas Phase Ion Chemistry

    • 1st Edition
    • Volume 3
    • N.G. Adams + 1 more
    • English
    Gas-phase ion chemistry is a broad field which has many applications and which encompasses various branches of chemistry and physics. An application that draws together many of these branches is the synthesis of molecules in interstellar clouds. This was part of the motivation for studies on the neutralization of ions by electrons and on isomerization in ion-neutral associations. The results of investigations of particular aspects of ion dynamics are presented in this volume. Solvation in ion-molecule reactions is discussed and extended to include multiply charged ions by the application of electrospray techniques. This volume also provides a wealth of information on reaction thermodynamics which is critical in determining reaction spontaneity and availability of reaction channels. More focused studies are also presented towards the end of this volume, relating to the ionization process and its nature.

  • Advances in Catalysis

    • 1st Edition
    • Volume 42
    • English
    Since 1948, this Series has filled the gap between the papers that report and the textbooks that teach in the diverse areas of catalysis research. The editors of and contributors to Advances in Catalysis are dedicated to recording progress in this area. Each volume of Advances in Catalysis contains articles covering a subject of broad interest.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 35
    • English
    Volume 35 reflects the new diverse utilization of NMR Spectroscopy, with four papers from very different areas of the field. These papers include not only recent developments in NMR but also its wide-ranging applications.

  • Alternative Careers in Science

    Leaving the Ivory Tower
    • 1st Edition
    • Cynthia Robbins-Roth
    • English
    Alternative Careers in Science describes the various career tracks available to scientists and gives the inside scoop on the skills and personality types suited to each profession. It also contains important information regarding career expectations and salary potential.This book will allow scientists to compare career opportunities. Each chapter covers a different career track and includes the basic job description, qualifications, responsibilities, and what career opportunities stem from each position.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 42
    • English
    This widely-acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964. Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambient temperatures to species which are thermally very stable. Organometallics are used extensively in the synthesis of useful compounds on both large and small scales. Industrial processes involving plastics, polymers, electronic materials, and pharmaceuticals all depend on advancements in organometallic chemistry. In basic research, organometallics have contributed inter alia to:* Metal cluster chemistry* Surface chemistry* The stabilization of highly reactive species by metal coordination* Chiral synthesis* The formulation of multiple bonds between carbon and the other elements and between the elements themselvesThis book is an essential reference work for the academic and industrial chemist and will provide up-to-date material at the cutting edge of chemistry research.

  • Theoretical and Mathematical Models in Polymer Research

    Modern Methods in Polymer Research and Technology
    • 1st Edition
    • Volume 5
    • Alexander Grosberg
    • English
    In this book, Professor Alexander Grosberg, one of the pioneers and leaders in the field of theoretical polymer science has selected the most important topics within polymer science and matched them with experts whocan clearly present the state of the art of each.Using this book readers will learn the fundamental concepts, as well as the techniques that are currently employed on the frontier of science.

  • Chemistry and Biology

    • 1st Edition
    • Volume 51
    • English
    Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind.

  • Analytical Profiles of Drug Substances and Excipients

    • 1st Edition
    • Volume 25
    • English
    Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the American Association of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.

  • The Combinatorial Index

    • 1st Edition
    • Barry A. Bunin
    • English
    With the explosion of combinatorial solid-phase methods, access to information has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a medicinal chemistry problem. The Combinatorial Index is an answer to that problem. This compendium of methods from the primary literature provides quick and convenient access to reliable synthetic transformations as well as information on linkers and analytical methods. Each synthetic procedure is preceded by a section entitled"Points of Interest,"which highlights the strengths and weaknesses of the various studies. The index also covers the use of solution-based synthesis for the generation of molecular diversity.

  • Trends in Drug Research II

    • 1st Edition
    • Volume 29
    • H. van der Goot
    • English
    This volume of Pharmacochemistry Library comprises the text of invited lectures presented at the 11th Noordwijkerhout-Came... Symposium Trends in Drug Research, held in Noordwijkerhout, The Netherlands, from 11-15 May 1997. In the programme attention has been given to the generation of new biological target systems and the generation of new lead molecules, with presentations on e.g. combinatorial chemistry, compound libraries, database search, high throughput screening and molecular biology. Other topics discussed were the perspectives for new medicines for the gastro-intestinal tract, the major developments in the search for effective anti-HIV drugs and new aspects in synthetic approaches. In a special session three topics which currently draw much attention were discussed: How to deal with the major problem of resistance against antimirobial agents? Can the apoptosis mechanism be used as a drug target? Is the newly observed phenomenon of inverse agonism a general principle and has it consequences for drug development (and use?)

  • Advances in Inorganic Chemistry

    • 1st Edition
    • Volume 45
    • English
    Advances in Inorganic Chemistry presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bioinorganic to solid state. This acclaimed serial features reviews written by experts in the area and is an indispensable reference to advanced researchers. Each volume of Advances in Inorganic Chemistry contains an index, and each chapter is fully referenced.

  • Stable Isotopes in Pharmaceutical Research

    • 1st Edition
    • Volume 26
    • T.R. Browne
    • English
    Stable isotope techniques offer advantages in safety, sensitivity, specificity, and economy for many types of pharmaceutical investigations when compared to conventional techniques. Nevertheless, pharmaceutical researchers are slow to embrace stable isotope techniques.This book assembles in one place comprehensive reviews of the many applications of stable isotopes and the background material necessary to understand the application. This approach is a deliberate attempt to encourage the usage of stable isotopes in pharmaceutical research. A bonus to the reader is the high standard of contributions from a very talented and diverse group of investigators.

  • Handbook of Chemometrics and Qualimetrics

    Part A
    • 1st Edition
    • Volume 20A
    • English

  • Theoretical Organic Chemistry

    • 1st Edition
    • Volume 5
    • C. Párkányi
    • English
    This volume is devoted to the various aspects of theoretical organic chemistry. In the nineteenth century, organic chemistry was primarily an experimental, empirical science. Throughout the twentieth century, the emphasis has been continually shifting to a more theoretical approach. Today, theoretical organic chemistry is a distinct area of research, with strong links to theoretical physical chemistry, quantum chemistry, computational chemistry, and physical organic chemistry.The objective in this volume has been to provide a cross-section of a number of interesting topics in theoretical organic chemistry, starting with a detailed account of the historical development of this discipline and including topics devoted to quantum chemistry, physical properties of organic compounds, their reactivity, their biological activity, and their excited-state properties.

  • Drops and Bubbles in Interfacial Research

    • 1st Edition
    • Volume 6
    • D. Mobius + 1 more
    • English
    The shape of drops and bubbles is the centre of interest for many interfacial scientists. This book describes the most recent accomplishments to make use of drops and bubbles in fundamental research and application.After a general introduction into the mechanics of liquid menisci, chapters are dedicated to methods based on drops or bubbles. The chapters about the three main drop experiments provide the theoretical basis, a description of experimental set-ups, specific advantages and disadvantages, correction and calibration problems, experimental examples and their interpretation: pendent and sessile drop, drop volume, and spinning drop technique. The chapter about capillary pressure methods summarises different techniques and gives examples of applications, for instance measurements under microgravity.The maximum bubble pressure technique as a particular capillary pressure method is described, with emphasis on the most recent developments which made this technique applicable to extremely short adsorption times, down to the range of milliseconds and less. Problems connected with aerodynamics and hydrodynamics are discussed and used to show the limits of this widely used standard method.The oscillating bubble technique provides information not available by other techniques, for example about the dilational rheology of adsorption layers and relaxation processes at the interface. The description of rising bubbles in surfactant solutions will contain the hydrodynamic basis as well as the theoretical description of the effect of interfacial layers on the movement of bubbles. Besides the theoretical basis experimental data, such as water purification, flotation processes etc. and the relevance for practical applications will be presented. The chapter about lung alveols demonstrates how important bubbles built by biological membranes are in everyday life. The relevance for medicine and biology as well as model studies is discussed.An important example for the application of drops is metallurgy, where the surface tension of metals and alloys is an important parameter for many applications. The chapters on drop shape analysis by using fibre technique and on force measurements between emulsion droplets are of much practical relevance.Lists of references and symbols are given separately at the end of each chapter while a common subject index is given at the end of the book.

  • Methods for Structure Elucidation by High-Resolution NMR

    Applications to Organic Molecules of Moderate Molecular Weight
    • 1st Edition
    • Volume 8
    • G. Batta + 2 more
    • English
    Nuclear Magnetic Resonance Spectroscopy (NMR) is now widely regarded as having evolved into a subscience. The field has become immensely diverse, ranging from medical use through solid state NMR to liquid state applications, with countless books and scientific journals devoted to these topics. Theoretical as well as experimental advance continues to be rapid, and has in fact accelerated by many novel innovations. This multi-authored book focuses on the latest developments in the rapidly evolving field of high resolution NMR, specifically with a view to applications on the structure elucidation of organic molecules of moderate molecular weight. Conceptually it differs from basic educational texts, hard-core scientific papers and regular review articles in that each chapter may be regarded as the authors' personal account of their special insights and results that crystallised after several years of research into a given topic. The book revolves around several themes and offers a handful of scientific "gems" of various colors, reflecting the great diversity of NMR. It contains 16 loosely connected chapters written by some of today's most accomplished NMR scientists in the world. Each chapter is a unique synthesis of the authors' previous research results in the given field, and thus projects special insights. Much emphasis has been given to the latest developments in NMR, in particular to selective pulses and pulsed field gradients. As a part of the series "Analytical Spectroscopy Library", with subsequent editions coming along this book should provide a platform for future research accounts of similar flavor. The material is presented in a mostly non-mathematical fashion, and is intended mainly for chemists, application NMR scientists and students with already some background in NMR. Some of the chapters slightly overlap in the discussed topics, which is particularly exciting in terms of gaining insight into the same area from different angles.

  • Advanced Problems in Organic Reaction Mechanisms

    • 1st Edition
    • Volume 16
    • English
    The Elsevier Tetrahedron Organic Chemistry Series is a topical series of monographs by world-renowned scientists in several fields of organic chemistry. The Tetrahedron Organic Chemistry Series has been very successful in providing some of the very best scholarly works in these topical areas that have proven to be of lasting quality as indispensable reference sources. These books have provided the practicing researcher, student and scholar with an invaluable source of comprehensive reviews in organic chemistry, predominantly in the areas of synthesis and structure determination, including:* Reagents* Reaction mechanisms* Molecular Diversity* Asymmetric Synthesis* Multi-dimensional nmr* Enzymatic Synthesis* Organometallic Chemistry* Biologically Important Molecules

  • Monosaccharide Sugars

    Chemical Synthesis by Chain Elongation, Degradation, and Epimerization
    • 1st Edition
    • Zoltan Gyorgydeak + 1 more
    • English
    In a single volume, Monosaccharide Sugars critically summarizes the applied and potentially useful strategies for the synthesis and degradation of monosaccharides by chain-elongation, degradation, and epimerization. These methodologies permit the synthesis of rare or unnatural monosaccharides that are frequently employed as chiral building blocks in natural products synthesis, as well as for producing sugar derivatives labeled with radioactive isotopes. Representative and well-established experimental procedures are provided to illustrate the potential of the synthetic transformation.Degra... of carbohydrates also represents an invaluable tool for the structural elucidation of certain natural products, suchas glycosides, antibiotics, and polysaccharides. When describing the individual methods, unique supplementary collections of the prepared sugar derivatives are shown in tabular form. This compendium will eliminate tedious literature searches for those engaged in research and teaching on the chemistry and biochemistry of saccharides and other natural products, and also for those working on the medicinal and metabolic investigation of related substances of biological importance.

  • Low-temperature Combustion and Autoignition

    • 1st Edition
    • Volume 35
    • M.J. Pilling
    • English
    Combustion has played a central role in the development of our civilization which it maintains today as its predominant source of energy. The aim of this book is to provide an understanding of both fundamental and applied aspects of low-temperature combustion chemistry and autoignition. The topic is rooted in classical observational science and has grown, through an increasing understanding of the linkage of the phenomenology to coupled chemical reactions, to quite profound advances in the chemical kinetics of both complex and elementary reactions. The driving force has been both the intrinsic interest of an old and intriguing phenomenon and the centrality of its applications to our economic prosperity. The volume provides a coherent view of the subject while, at the same time, each chapter is self-contained.

  • Applied Process Design for Chemical and Petrochemical Plants: Volume 2

    • 3rd Edition
    • Ernest E. Ludwig
    • English
    This latest edition covers the technical performance and mechanical details of converting the chemical and petrochemical process into appropriate hardware for distillation and packed towers. It incorporates recent advances and major innovations in distillation contacting devices and features new generations of packing. In addition, this new edition reflects the significant progress that has been made in process design techniques in recent years. Volume 2's example calculation techniques guide in the preparation of preliminary and final rating designs. In some instances, the book includes manufacturers' procedures and notes clearly indicate when manufacturers should verify results.

  • Advances in DNA Sequence-specific Agents

    • 1st Edition
    • Volume 3
    • M. Palumbo
    • English
    In this volume the entire focus is devoted to the macromolecule target specificity of DNA interactive developmental therapeutic agents of current interest. A brief introduction to DNA interactive anticancer agents is included for readers who may benefit from an overview surrounding the developments that have contributed to our general understanding of this field. The following nine chapters have been carefully chosen so that they describe topics which are at the forefront of development in DNA-targeted cancer chemotherapy. Issues that have been addressed include the mechanisms of selective DNA topoisomerase I and II poisoning by antitumor agents (Chapters 1 and 2), sequence-specific recognition of DNA by groove-binding drugs and drug-conjugates (Chapters 3 and 4), recent developments in nitrogen mustard alkylating agents and their potential use for antibody-directed enzyme-prodrug therapy (Chapter 5), nonclassical platinum anticancer complexes, including dinuclear and trans-platinum derivatives (Chapter 6), DNA cleaving antitumor chromoproteins containing reactive enediyne moieties, which exhibit interesting free-radical chemistry along with selective targeting (Chapter 7), the potential of new sequence-specific antisense and antigene therapy in oncology (Chapter 8), and finally the conceivable chemotherapeutic use of mimetics of the DNA structure, obtained by substitution of the sugar-phosphate natural chain with a peptide backbone, the so-called peptide nucleic acids (Chapter 9). Important approaches being currently investigated for selective cancer treatment, such as gene therapy and immunochemotherapy, are not discussed in this volume since they fall beyond its scope.

  • Advances in Amino Acid Mimetics and Peptidomimetics

    • 1st Edition
    • Volume 1
    • A. Abell
    • English
    Peptidomimetics are compounds which mimic the biological activity of peptides while offering the advantages of increased bioavailability, biostability, bioefficiency, and bioselectivity against the natural biological target of the parent peptide. Examples of peptidomimetics have been isolated as natural products, synthesized as libraries from novel subunits, and designed on the basis of X-ray crystallographic studies and through an intricate knowledge of the biological mode of action of natural peptides. They offer challenging synthetic targets and are increasingly important medicinal agents and biological probes. As a consequence, peptidomimetics embrace much of what is modern medicinal and organic chemistry. This volume highlights some recent and exciting developments in the area.

  • Chemistry of the Elements

    • 2nd Edition
    • N. N. Greenwood + 1 more
    • English
    When this innovative textbook first appeared in 1984 it rapidly became a great success throughout the world and has already been translated into several European and Asian languages. Now the authors have completely revised and updated the text, including more than 2000 new literature references to work published since the first edition. No page has been left unaltered but the novel features which proved so attractive have been retained. The book presents a balanced, coherent and comprehensive account of the chemistry of the elements for both undergraduate and postgraduate students. This crucial central area of chemistry is full of ingenious experiments, intriguing compounds and exciting new discoveries. The authors specifically avoid the term `inorganic chemistry' since this evokes an outmoded view of chemistry which is no longer appropriate in the final decade of the 20th century. Accordingly, the book covers not only the 'inorganic' chemistry of the elements, but also analytical, theoretical, industrial, organometallic, bio-inorganic and other cognate areas of chemistry. The authors have broken with recent tradition in the teaching of their subject and adopted a new and highly successful approach based on descriptive chemistry. The chemistry of the elements is still discussed within the context of an underlying theoretical framework, giving cohesion and structure to the text, but at all times the chemical facts are emphasized. Students are invited to enter the exciting world of chemical phenomena with a sound knowledge and understanding of the subject, to approach experimentation with an open mind, and to assess observations reliably. This is a book that students will not only value during their formal education, but will keep and refer to throughout their careers as chemists.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 70
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 69
    • English
    This volume includes the third, and final, part of a trilogy on acyclonucleosides by E.S.H. El Ashry and Y. El Kilany which began in Volume 67. This chapter covers tri-, tetra-, and penta- seco-nucleosides. These compounds are of considerable interest due to their relationship to newer anti AIDS drugs. Other chapters deal with the use of organohypervalent iodine reagents in the synthesis of organic compounds, a review of the conformational analysis of saturated 6-membered oxygen containing rings, comprising the oxanes, the various dioxanes, trioxanes, and tetroxanes, and heteropentalenes with fused imidazoles of 1,2,4-triazole rings.

  • Synthetic and Stereochemical Aspects

    • 1st Edition
    • Volume 2
    • Philip Page
    • English
    The impact of organosulfur chemistry, especially in the areas of heterocyclic chemistry, stereocontrolled processes, and asymmetric synthesis, has led to a resurgence of interest in the field. This book is the secondin a series intended to provide coverage of topics of current interest throughout the whole range of organosulfur chemistry. Each volume is comprised of five or six chapters, each consisting of an in-depth, self-contained review in a well-defined area. This volume and its predecessor Organosulfur Chemistry, Synthetic Aspects will prove valuable references for researchers and practitioners in organic chemistry.

  • Chemistry and Biology

    • 1st Edition
    • Volume 50
    • English
    Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 32
    • James A. Bristol
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.

  • Fundamentals of Inorganic Chemistry

    An Introductory Text for Degree Studies
    • 1st Edition
    • J Barrett + 1 more
    • English
    This work is a foundation course text for first and second year undergraduates in which description and understanding of inorganic chemistry are fully integrated. It covers the main underlying theoretical ideas, taking account of the level of mathematical ability among present-day students commencing university study. Each chapter provides "worked example" problems, supported by additional problem-exercises which test comprehension and serve for revision or self-study.

  • Structure and Chemistry (Part E)

    • 1st Edition
    • Volume 19
    • Atta-ur Rahman
    • English

  • Macromolecular Crystallography, Part B

    • 1st Edition
    • Volume 277
    • John N. Abelson + 1 more
    • English
    Macromolecular Crystallography, Part B is the"linch-pin"of the ongoing revolution in structural biology. In the past decade, fundamental transformations of nearly every technical aspect of structure determination by X-ray diffraction have taken place. The contributions of this volume and its companion Volume 276 emphasize the revision and extension of statistical tools that underly all phases of structure determination, the practical and conceptual impact of synchrotron radiation, horizon phase-determination methods, and computerized automation.

  • Advances in Supramolecular Chemistry

    • 1st Edition
    • Volume 4
    • G.W. Gokel
    • English
    Part of a series which presents reports of efforts in all areas of supramolecular science, this volume discusses a variety of topics in the field.

  • Analytical Gas Chromatography

    • 2nd Edition
    • Walter Jennings + 2 more
    • English
    Gas chromatography remains the world's most widely used analytical technique, yet the expertise of a large proportion of chromatographers lies in other fields. Many users have little real knowledge of the variablesin the chromatographic process, the interaction between those variables, how they are best controlled, how the quality of their analytical results could be improved, and how analysis times can be shortened to facilitate the generation of a greater numberof more reliable results on the same equipment. An analyst with a more comprehensive understanding of chromatographic principles and practice, however, can often improve the quality of the data generated, reduce the analytical time, and forestall the needto purchase an additional chromatograph or another mass spectrometer. The Second Edition of Analytical Gas Chromatography is extensively revised with selected areas expanded and many new explanations and figures. The section on sample injection has been updated to include newer concepts of split, splitless, hot and cold on-column, programmed temperature vaporization, and large volume injections. Coverage of stationary phases now includes discussion, applications, and rationale of the increased thermal and oxidative resistance of the newly designed silarylenepolysiloxa... polymers. Conventional and"extended range"polyethylene glycol stationary phases are examined from the viewpoints of temperature range and retention index reliabilities, and the chapter on"Variables"has been completely rewritten. The ways in which carrier gas velocity influences chromatographic performance is considered in detail, and includes what may be the first rational explanation of the seemingly anomalous effects that temperature exercises on gas viscosity (and gas flow). The practical effects that these changes cause to the chromatography is examined in pressure-, flow-, and"EPC-"regulated systems."Column Selection, Installation, and Use"has been completely rewritten as well. The accuracy of theVan Deemter plots has been greatly enhanced; a new program corrects for the first time for the changes in gas density and diffusion that occur during the chromatographic process because of solute progression through the pressure drop of the column. A new section has also been added on meeting thespecial requirements of columns destined for mass spectral analysis. The chapter on"Special Applications"has been expanded to include considerations of"selectivity tuning,"of fast analysis, and the section of Applications has been thoroughly updated and expanded.

  • Annual Reports in Organic Synthesis 1997

    • 1st Edition
    • English
    This handy inexpensive reference tool is an organized annual review of synthetically useful information. It abstracts synthetic reactions from the major chemistry journals of the past year and includes reactions and methods that are new and reasonably general. The reactions are presented in a convenient pictorial format designed for rapid visual retrieval of information. A comprehensive table of contents and a senior author index are included.The Journal of the American Chemical Society has aptly described this publication as an "aid to the harassed organic chemist who cannot keep up with the never-diminishing stream of new primary literature" and hails it "an outstandingly good buy."

  • Gas Purification

    • 5th Edition
    • Arthur L Kohl + 1 more
    • English
    This massively updated and expanded fifth edition is the most complete, authoritative engineering treatment of the dehydration and gas purification processes used in industry today. Of great value to design and operations engineers, it gives practical process and equipment design descriptions, basic data, plant performance results, and other detailed information on gas purification processes and hardware. This latest edition incorporates all significant advances in the field since 1985.You will find major new chapters on the rapidly expanding technologies of nitrogen oxide control, with discussions of regulatory requirements and available processes; absorption in physical solvents, covering single component and mixed solvent systems; and membrane permeation, with emphasis on the gas purification applications of membrane units. In addition, new sections cover areas of strong current interest, particularly liquid hydrocarbon treating, Claus plant tail gas treating, thermal oxidation of volatile organic compounds, and sulfur scavenging processes.This volume brings you expanded coverage of alkanolamines for hydrogen sulfide and carbon dioxide removal, the removal and use of ammonia in gas purification, the use of alkaline salt solutions for acid gas removal, and the use of water to absorb gas impurities. The basic technologies and all significant advances in the following areas are thoroughly described: sulfur dioxide removal and recovery processes, processes for converting hydrogen sulfide to sulfur, liquid phase oxidation processes for hydrogen sulfide removal, the absorption of water vapor by dehydrating solutions, gas dehydration and purification by adsorption, and the catalytic and thermal conversion of gas impurities.

  • Expanded, Contracted & Isomeric Porphyrins

    • 1st Edition
    • Volume 15
    • J.L. Sessler + 1 more
    • English
    The porphyrins are a class of naturally-occurring macrocycles and are ubiquitous in our world. As such, they have been called the Pigments of Life. This auspicious designation reflects their importance in numerous biological functions. Indeed, life as we understand it relies on the full range of biological processes that are either performed by or catalyzed by porphyrin-containing proteins. Chlorophyll-containi... photosynthetic reaction centers in plants, for instance, convert light energy into chemical energy while producing oxygen along the way. It is this oxygen, evolved from photosynthesis, that is transported, stored, and reduced by heme-containing proteins in many organisms, including mammals. Not surprisingly, therefore, these molecules remain of fundamental interest to chemists and biochemists. Indeed, they continue to be intensely investigated by researchers world-wide.Inspired by the importance of the porphyrins, a new research direction has emerged in recent years that is devoted to the preparation and study of non-porphyrin polypyrrole macrocycles. Here, the principal objectives have been to generate completely synthetic systems that bear some structural resemblance to naturally-occurring porphyrin derivatives while being quite different in their specific chemical makeup. Within this context, three different research directions have evolved, namely those involving the syntheses of contracted, isomeric, and expanded porphyrins, respectively. It is the chemistry of these systems that is the subject of this book. Because of the newness of the field, the emphasis of this book will be on synthesis and characterization (all work on porphyrin isomers and much of that associated with expanded porphyrins has only appeared in the last 10 years). One chapter on applications has, however, been included. Also, in the context of the preparative portions of the text, some efforts have been made to explain why various porphyrin analogue targets are of interest.

  • Progress in Heterocyclic Chemistry

    A Critical Review of the 1996 Literature Preceded by Two Chapters on Current Heterocyclic Topics
    • 1st Edition
    • Volume 9
    • Thomas L. Gilchrist + 1 more
    • English
    Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). The volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and articles on new developing topics of interest to heterocyclic chemists.The highlight chapters in Volume 9 are all written by leading researchers in their field and these chapters constitute a systematic survey of the important original material reported in the literature on heterocyclic chemistry in 1996. Additional articles in this volume also review "The Synthesis of Oxazoles from Diazocarbonyl Compounds" and "The Heterocyclic Chemistry Associated with the Herbicide Glyphosate".As with previous volumes in the series, Volume 9 will enable academic and industrial chemists, and advanced students to keep abreast of developments in heterocyclic chemistry in an effortless way.

  • High Performance Liquid Chromatography & Capillary Electrophoresis

    Principles and Practices
    • 1st Edition
    • Andrea Weston + 1 more
    • English
    HPLC and CE: Principles and Practice presents the latest information on the most powerful separation techniques available: high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE). Fundamental theory, instrumentation, modes of operation, and optimization of separations are presented in a concise, non-technical style to help the user in choosing the appropriate technique quickly and accurately. Well- illustrated and containing convenientend-of-cha... summaries of the major concepts, the book provides in-depth coverage of trouble-shooting, improvement of resolution, data manipulation, selectivity, and sensitivity.Graduate students, technicians, and researchers who must use separations with little or no background in analytical chemistry can overcome separation anxiety and get started in obtaining the best possible separations in minimal time. The book will alsobe useful to analytical chemists who need a better understanding of theory and processes.

  • Techniques in Protein Chemistry

    • 1st Edition
    • Volume 8
    • English
    Praise for the Series:"The mainly sharp scientific focus of this set of snapshots is a credit to both the contricutors and the editorial team."--Biotechnolog... and Applied Biochemistry Techniques in Protein Chemistry VIII is the latest volume in this successful series. As a valuable bench-top reference tool for protein chemists, the ten section sof the book are divided by subject area to show the reader which techniques are currently applied to particular problems in protein science. This approach reflects current trends in which specific instruments and methodologies are used in several different areas.

  • Serotonin Receptors and their Ligands

    • 1st Edition
    • Volume 27
    • B. Olivier + 2 more
    • English
    An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds (selectively) acting at serotonin receptors or serotonin transporters either as agonists, partial agonists or antagonists.Structur... - affinity relationships and structure - activity relationships of agonists, partial agonists, and antagonists of 5-HT receptors and uptake sites, are discussed. Structure, sequence homology and the effect of site-directed mutations of 5-HT receptors and the reuptake site on the binding of ligands show the tremendous impact of molecular biology on medicinal chemistry research. Also discussed is the pharmacology and (potential) clinical applications of ligands for the 5-HT receptors and the reuptake site. By developing elegant techniques of cloning and expression of serotonin receptor subtypes, their mutants and chimeras, a unique opportunity was offered to study the binding mode of serotoninergic ligands to their receptors and transporters.The distribution, structure and homologies of serotonin receptor subtypes and the structure of the serotonin transporter are also taken into account.The (potential) therapeutic applications of ligands of the different subtypes are described.Altogether an excellent addition to the Pharmacochemical Library series.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 52
    • English
    Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists in industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 34
    • English
    NMR is used in all areas of modern science, and its applications continue to grow. In 1995 we celebrated the 50th anniversary of the discovery of NMR Spectroscopy and almost 30 years since the appearance of the firstvolume of Annual Reports on NMR Spectroscopy. During these years, a large and diverse collection of topics have been covered, and the contents of Volume 34 are no exception. This volume consists of six chapters covering a wide range of polymer science topics. Each chapter demonstrates the unique ability of NMR to provide information of both general and special interests.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 41
    • English
    This widely-acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964. Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon–metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambienttemperatures to species which are thermally very stable. Organometallics are used extensively in the synthesis of useful compounds on both large and small scales. Industrial processes involving plastics, polymers, electronic materials, and pharmaceuticals all depend on advancements in organometallic chemistry.This book is an essential reference work for the academic and industrial chemist and will provide up-to-date material at the cutting edge of chemistry research.

  • Growth and Properties of Ultrathin Epitaxial Layers

    • 1st Edition
    • Volume 8
    • English
    Although there has been steady progress in understanding aspects of epitaxial growth throughout the last 30 years of modern surface science, work in this area has intensified greatly in the last 5 years. A number of factors have contributed to this expansion. One has been the general trend in surface science to tackle problems of increasing complexity as confidence is gained in the methodology, so for example, the role of oxide/metal interfaces in determining the properties of many practical supported catalysts is now being explored in greater detail. A second factor is the recognition of the potential importance of artificial multilayer materials not only in semiconductor devices but also in metal/metal systems because of their novel magnetic properties. Perhaps even more important than either of these application areas, however, is the newly-discovered power of scanning probe microscopies, and most notably scanning tunneling microscopy (STM), to provide the means to study epitaxial growth phenomena on an atomic scale under a wide range of conditions. These techniques have also contributed to revitalised interest in methods of fabricating and exploiting artificial structures (lateral as well as in layers) on a nanometre scale.This volume, on Growth and Properties of Ultrathin Epitaxial Layers, includes a collection of articles which reflects the present state of activity in this field. The emphasis is on metals and oxides rather than semiconductors.

  • Chemistry and Pharmacology

    • 1st Edition
    • Volume 49
    • English
    Internationally acclaimed for more than 40 years, this Series, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this Series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all naturalproduct chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.

  • Imidazole and Benzimidazole Synthesis

    • 1st Edition
    • M. R. Grimmett
    • English
    Imidazole and Benzimidazole Synthesis is a comprehensive survey of the known methods of syntheses and ring modification. It brings together the multitude of synthesis of the imidazole ring in a systemic way interms of specific bond formation, and recommends the most attractive synthetic approaches. It also collects non-ring-synthetic approaches to classes of compounds such as nitro-, halogeno-, and amino-imidazoles, and covers the synthesis of N-substituted compounds and preparations of specific isomers.

  • Advances in Asymmetric Synthesis

    • 1st Edition
    • Volume 2
    • Bozzano G Luisa
    • English

  • Biotechnological Innovations in Chemical Synthesis

    • 1st Edition
    • BIOTOL + 2 more
    • English
    Demonstrates how biological catalysis can be applied to the production of value added chemicals. Use is made of a diverse range of case studies to give a breadth of experience. It also reveals how bio-systems are being employed to produce a wide range of valuable commodities including antibiotics and other therapeutics, intermediary metabolites such as citrate, malate, gels and other valuable polymers.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 68
    • English
    The first chapter in this volume, by E.S.H. El-Ashry, represents the second part of a trilogy on nucleosides he began in Volume 67. This chapter deals with diseco-nucleosides, or analogs of nucleosides in which thereare two bond disconnections. Other chapters deal with the importance of cyclic sulfates as intermediates in organic synthesis, methlypyridines and other methylazines as precursors to biand polyheterocycles, and the variety of heterocycles in nucleoside analogs in heteromonocyclic bases.

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