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Elsevier

Books in Life sciences

  • ​​Environmental Greenness and Cardiovascular Health​

    • 1st Edition
    • William W. Aitken
    • English
    Environmental Greenness and Cardiovascular Health provides a comprehensive understanding of how environmental factors, particularly green spaces, impact cardiovascular health. The book bridges environmental science and medical research, offering insights into how greenness contributes to the prevention and management of cardiovascular diseases.Environment... Greenness and Cardiovascular Health begins with an introduction to cardiovascular disease and environmental factors, followed by discussions on defining and measuring greenness, historical perspectives, and the physiological and psychological benefits of green spaces. It also covers urban planning, disparities in access to green spaces, longitudinal studies, future research directions, and policy implications. Environmental Greenness and Cardiovascular Health benefits researchers, medical practitioners, urban planners, and policymakers by providing the latest methodologies, practical examples, and policy recommendations. It serves as an essential resource for understanding the intersection of environment and health, promoting informed strategies for improving cardiovascular health through environmental interventions.

  • Next-Generation Cereal-Based Foods and Beverages: Breakthroughs in Technology, Sustainability, and Health

    • 1st Edition
    • Volume 117
    • English
    Next-Generation Cereal-Based Foods and Beverages: Breakthroughs in Technology, Sustainability, and Health, Volume 117 offers an in-depth examination of the latest advancements in cereal science, processing techniques, and health-oriented applications. This volume gathers insights from global experts, focusing on functional ingredient development, foodomics, and novel analytical methods aimed at improving nutritional quality, safety, and sensory features of cereal-based products. The book delves into breakthroughs in extrusion, fermentation, and milling technologies, emphasizing the significance of non-starch carbohydrates, bioactive compounds, and plant-based protein alternatives in driving sustainable food systems.It also covers consumer behavior, regulatory issues, and industry challenges, making it an essential resource for scientists, food industry professionals, and policymakers committed to creating the next generation of health-enhancing and environmentally friendly cereal foods and beverages.

  • The Scientific Basis of Fatigue

    • 1st Edition
    • Colin R. Martin + 3 more
    • English
    Fatigue is a prevalent problem and adequate treatment is challenging because many conditions, disorders, medications, and lifestyle factors can cause fatigue. The Scientific Basis of Fatigue combines evidence-based research and clinical treatment protocols to provide a comprehensive reference to fatigue. This book is divided into seven distinct sections, starting with an introduction section defining the distinctions between physical and mental fatigue. The second and third sections detail the various conditions in both physical and mental fatigue including COVID, Parkinson disease, and depression. The next section reviews the current research on molecular and cellular aspects and models of fatigue. The final two sections review options for diagnosis and treatments for fatigue and provides a detailed resource section for further review.

  • New Opioid Receptor Modulators and Agonists

    Relevance for Pain and Opioid Use Disorder Management
    • 1st Edition
    • Alan David Kaye + 1 more
    • English
    New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research.It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.

  • Mitochondrial Signaling and Regulation

    Immune Responses and Diseases
    • 1st Edition
    • Seyyed Shamsadin Athari + 1 more
    • English
    Mitochondrial Signaling and Regulation: Immune Responses and Diseases delves into the latest research on molecular pathophysiology mechanisms and cell signaling pathways in the pathogenesis of diseases via mitochondrial regulation. This comprehensive study underscores the importance of mitochondria in cellular processes and their role in disease development. Early chapters discuss the crucial role, regulation, and crosstalk of mitochondria, highlighting their significance in maintaining cellular health. The exploration of mitochondria mutations and mitochondria-related diseases follows, providing a detailed understanding of the genetic aspects involved.Final chapters focus on mitochondria's involvement in immune responses and allegro-inflammation... presenting the intricate connections between mitochondrial function and the immune system. The book also explores the use of biotechnology in developing new treatments and targeted therapies against mitochondrial dysfunction. This resource sets the foundation for new classifications, prevention methods, therapies, and treatments of mitochondria-related diseases, making it invaluable for scientists and researchers dedicated to this field.

  • Food and Agro-Industrial Wastes

    Sustainable Impacts, Transformation and Added Value of By-products
    • 1st Edition
    • Mika Sillanpää + 2 more
    • English
    Food and Agro-Industrial Wastes: Sustainable Impacts, Transformation and Added Value of By-Products offers an in-depth look at the potential of recycling food and agro-industrial waste into valuable products. This book presents the concept of sustainable development through responsible consumption and production, and introduces practical methods to transform waste into new, value-added products. It delves into various industries, such as meat, dairy, and crop processing, highlighting the ways in which residues like leaves, stems, and husks can be repurposed. Moreover, the book explores the valorization and safety of fruit and vegetable waste, including peels and skins, to enhance food products.Real-life case studies showcase how bioactive compounds, nutraceuticals, and other bio-based enzymes can be derived from waste, providing insights into innovative food product development. This comprehensive guide is an essential resource for anyone interested in sustainable waste management and the creation of functional, eco-friendly products. Globally, it is estimated 1.3 billion tons of food, valued at $1 trillion is wasted a year, according to the United Nations and the Food and Agriculture Organization. (FAO) In addition, billions of tons of agro-industrial waste from agriculture and food processing activities are generated yearly, putting a strain on natural resources, and negatively effecting the environment.

  • Sparkling Beverages

    Champagne and Beyond
    • 1st Edition
    • Gérard Liger-Belair
    • English
    Sparkling Beverages: Champagne and Beyond offers a complete overview of the physicochemical processes at work in a sparkling beverage. In order to achieve effervescence in a glass of champagne, precise knowledge fluid dynamics and CO2 solubility are necessary. This reference covers these concepts, as well as historical contexts and modern-day production methods of simple sparkling waters and sugar-free sparkling soft drinks to more complex alcoholic beverages, such as beers or sparkling wines. The book breaks down the science behind the fizz in our drinks while also examining sensory experiences associated with opening, smelling, and testing sparkling beverages.Written by a true expert on the topic and complete with beautiful, original photography, this unique, interdisciplinary work will interest researchers and industry producers alike.

  • Seafood 4.0

    Digital, Physical, and Biological Innovations from Sea to Table
    • 1st Edition
    • Abdo Hassoun + 1 more
    • English
    Seafood 4.0: Digital, Physical, and Biological Innovations From Sea to Table serves as a comprehensivesource of information about the fourth industrial revolution (Industry 4.0) innovations and relevanttechnologies used in fisheries, aquaculture, and the seafood industry. The book is divided into fivesections, each exploring recent groundbreaking innovations and technological advances that enhanceseafood quality, safety, and traceability. These advancements hold strong potential to reduce seafoodwaste and production costs while simultaneously improving marine sustainability, enabling effectivemanagement of this valuable food resource across the entire seafood value chain from sea to table.The chapters address the current challenges and future research directions needed to accelerate theadoption of Industry 4.0 technologies in the seafood sector. Additionally, the book sets the stage forthe next wave of innovation, paving the way for the future revolution of Seafood 5.0.Promoting multidisciplinary collaboration and accelerating the adoption of Industry 4.0 technologies,this book highlights how these innovations can lead to smart production, processing, supply chainmanagement, and consumer engagement, making it a valuable resource for anyone involved in theseafood supply chain, from production to consumption.

  • Innovation in Cell Death Research

    • 1st Edition
    • Volume 217
    • English
    Innovation in Cell Death Research, Volume 217 covers topics relating to the identification of unique signaling pathways, the discovery of biomarkers and innovative treatment strategies, neurodegenerative diseases, and immune-related disorders. Chapters in this new release include Cell Death Triad: Integrating Apoptotic, Autophagic, and Necrotic Cell Death Mechanisms, Advances in Cell Death Detection and Imaging, Informatic and data science for the cell death researches, Visualizing and Mapping Cell Death: Biochemical Tools, Techniques and Assays, and the Role of Autophagy in Cell Death and Survival: Mechanisms and Therapeutic Implications.Other sections cover the Role and Relation of Cell Death in Cancer Disease, Exploring Pyroptosis: From molecular mechanisms to cancer therapeutics, Current findings and potential applications of cell death research in ovarian cancer, PHAGEPTOSIS: A BACTERIAL CELL DEATH PROGRAM INDUCED BY CRISPR-CAS SYSTEMS, Cell death mechanisms in Drosophila: Responses to infectious challenges, and much more.

  • Encyclopedia of Evolutionary Biology

    • 2nd Edition
    • Claudia Augusta De Moraes Russo + 1 more
    • English
    Encyclopedia of Evolutionary Biology, Second Edition, Four Volume Set is a comprehensive resource containing approximately 215 chapters that covers all fundamental topics in evolutionary biology. Featuring a consistent chapter structure, this encyclopedia ensures easy navigation across the volumes. Each chapter effectively links concepts to specific systems and examples, making it an invaluable tool for anyone interested in applying evolutionary thinking to their field of study. This edition includes new or expanded topics such as human evolution, including cultural evolution and language, paleontology, the origins of life, mass extinction events, epigenetics, and metagenomics.The encyclopedia also delves into the evolution of behavior, game theory, kin selection, optimality, human microbiomes, and the diversification of viruses. With its broad coverage, this essential resource will engage readers across various educational levels, emphasizing the central role of evolutionary biology in the life sciences. It caters to a wide range of readers, from students to experienced professionals, by offering both introductory chapters and in-depth analyses.

  • Protein Termini Part B

    • 1st Edition
    • Volume 719
    • English
    Protein termini represent a major route to protein regulation. From the moment the very first amino acid of a polypeptide chain exits the ribosome there is potential for steering from the cellular environment. This volume of <i>Methods in Enzymology Modifications and Targeting of Protein Termini</i> focuses on Protein N-termini and C-termini and their modifications which include acetylation, arginylation, myristoylation and oxidation. Also, the impact of terminal modifications is covered, in particular the impact on protein turnover and the ubiquitin E3 ligases which specifically recognize protein N-termini (N-degrons) and C-termini (C-degrons). In addition to the detailed methods and laboratory protocols, the chapters include informative overviews and reviews of the different subfields.

  • Feedback Control and Adaptive Learning in Optical-Tweezer Robotics

    • 1st Edition
    • Xiang Li + 2 more
    • English
    Feedback Control and Adaptive Learning in Optical-Tweezer Robotics is a comprehensive guide to merging robotic feedback control with optical trapping techniques in cell manipulation. It begins by providing foundational knowledge in dynamic modeling and control theory, essential for understanding optical-tweezer robotics' complexities. The book explores optical trapping principles, discussing traditional approaches' constraints and challenges. It then introduces a unified control methodology designed for dynamic adaptation to cell movement and escape scenarios, highlighting the importance of closed-loop control strategies in navigating the interaction between optical forces and robotic manipulation.Additio... the book delves into adaptive learning algorithms for real-time adjustments in unknown trapping stiffness, addressing challenges like limited field of view, stochastic disturbances, and handling multiple cells. It integrates open-access simulations and real-world experiments to reinforce theoretical concepts, offering practical examples. This unified approach's potential impact on biomedicine, biotechnology, and microscale robotics is emphasized, making it an invaluable resource for readers in these fields.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 132
    • English
    Advances in Applied Microbiology, Volume 132 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • Development of Sensory Organs

    • 1st Edition
    • Volume 165
    • English
    Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Robotics and Artificial Intelligence for Reproductive Medicine

    • 1st Edition
    • Guanqiao Shan + 3 more
    • English
    Robotics and Artificial Intelligence for Reproductive Medicine provides fundamental principles underpinning robotic and AI techniques used for reproductive medicine. The book provides the state-of-the-art technical advances in clinical infertility treatment, along with the outlook on future challenges and opportunities of robotics and AI in reproductive medicine. It covers robotics, AI, computer vision, biomedical engineering, and reproductive medicine.

  • Artificial Intelligence in Food Science

    Transforming Food and Bioprocess Development
    • 1st Edition
    • Tanmay Sarkar + 1 more
    • English
    Artificial Intelligence in Food Science: Transforming Food and Bioprocess Development covers the AI and machine learning techniques that are reshaping the food science landscape, introducing innovative solutions to improve food processing, safety, and sustainability. This book delves into the transformative potential of these cutting-edge technologies, exploring how they optimize food production, enhance bioprocess development, and tailor products to meet specific consumer needs. By integrating AI, researchers and industry professionals can address challenges such as resource efficiency and quality assurance, paving the way for a more sustainable and technologically advanced food system.Beyond optimization, the book examines AI applications in predicting food trends, analyzing complex datasets, and developing personalized nutrition plans. It provides insights into how AI enhances food storage, packaging design, and even consumer engagement through predictive models. With detailed case studies and forward-thinking perspectives, this book serves as a comprehensive guide for harnessing AI's power to revolutionize food science and bioprocess innovations.

  • Deep Learning in Drug Design

    Methods and Applications
    • 1st Edition
    • Qifeng Bai + 2 more
    • English
    Deep Learning in Drug Design: Methods and Applications summarizes the most recent methods, and technological advances of deep learning for drug design, which mainly consists of molecular representations, the architectures of deep learning, geometric deep learning, large models, etc., as well as deep learning applications in various aspects of drug design. This book offers a comprehensive academic overview of deep learning in drug design. It begins with molecular representations, CNNs, GNNs, Transformers, generative models, explainable AI, large models, etc. Next, it covers deep learning applications like protein structure prediction, molecular interactions, ADMET prediction, antibody design, and so on. Finally, a separate chapter is dedicated to the introduction of the ethics and regulation of artificial intelligence in drug design. This book is ideal for readers aiming to learn and implement deep learning methods and applications in drug design and related fields.Deep Learning in Drug Design: Methods and Applications is particularly helpful to undergraduate, graduate, and doctoral students in need of a practical guide to the principles of the discipline. Established researchers in the area will benefit from the detailed case studies and algorithms presented.

  • Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma

    • 1st Edition
    • Rajeev Sharma + 4 more
    • English
    Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that are required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach. In 18 chapters, this title sets forth the rationales for promising therapies like immunotherapy, including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy.In addition, the book reviews potential novel agents, the current status of preclinical and clinical trials, and the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • The Times They are A-Changin´: On Cannabinoids and Psychedelics´ Therapeutic Potential and Social Impact

    • 1st Edition
    • Volume 296
    • English
    Cannabinoids and Psychedelics: A Therapeutic Revolution, Volume 296 offers original research, reviews, and essays, including basic science and clinical studies on cannabinoids and psychedelics. This includes basic works on the neurotransmitter systems, the effects of drugs on animal and human perception, and emotion and cognition. Chapters in this new release include Chemical diversity, receptor binding affinity and pharmacology of phytocannabinoids: insights into neuronal mechanisms, Does cannabis work for insomnia?, Testing NPSs as harm reduction strategies, Cannabis-based products in Brazil: regulation for quality improvement, Anti-prohibitionist social movement in Brazil and the strength of the Marijuana Marches, and much more.Other chapters include discussions on Philopsychedelia: The Reflorescence of Psychedelic Philosophy, Psychedelics in Palliative Care: Transcending Death and Alleviating Spiritual Suffering, High dreams: inhaled DMT increase lucid dreams and nightmares, Malaise in the psychedelic revolution: when and for whom this movement brings opportunities, and the Neurophenomenology of psychedelic-induced mystical experiences.

  • Aging in Ophthalmology

    • 1st Edition
    • Jorge L Alio MD + 2 more
    • English
    Aging in Ophthalmology examines the aging process of the eye and how this affects the future of ophthalmology. With a strong focus on therapeutic options, the book shows the latest improvements in medical and surgical possibilities. It describes both the risks of the aging of the eye, the aging of different parts of the eye (like the retina, lens, and iris), therapeutic approaches to limit the aging processes of the eye, along with a glance into the future. This book is a valuable resource for ophthalmologists of all subspecialties and researchers interested in the aging process in the human eye.

  • Sports Physician Handbook

    • 4th Edition
    • Yannis P. Pitsiladis + 3 more
    • English
    Sports Physician Handbook, the fourth edition of the Team Physician Manual: International Federation of Sports Medicine (FIMS), covers all key areas of activity and intervention, from the preparticipation examination to rehabilitation, drug testing, care of the young athlete, the female athlete, and environmental issues. The book also surveys major classifications of sports injuries, offering clear advice on field side assessment, diagnosis, and treatment. It further examines best practices in broader aspects of sports medicine, such as injury prevention and the psychology of recovery. Sports Physician Handbook continues the tradition of high-caliber authorship, featuring contributions from world-leading physicians and scientists. In short, the fourth edition represents a "must-have" reference for any doctor, scientist, physical therapist, or medical professional working in sport.

  • CRISPR Technology for Combating Plant Pests and Pathogens

    • 1st Edition
    • Jen-Tsung Chen
    • English
    CRISPR Technology for Combating Plant Pests and Pathogens improves the understanding of CRISPR-mediated crop protection, presenting innovative strategies for developing disease-resistant crops that can withstand a variety of biotic stresses.In agricultural food production, a range of stressors continues to challenge crop production globally. Fortunately, modern crop breeding approaches have developed rapidly, including the promising technology of plant genome editing. Leading to improvements in disease resilience or stress-tolerant crops, CRISPR/Cas9 is among the mainstream genome editing technologies for plant breeding precision and efficiency.CRISPR Technology for Combating Plant Pests and Pathogens offers in-depth summaries curated by leading experts and professors in the field of agricultural biotechnology, providing the essential knowledge needed to advance research and applications in crop resilience.

  • Sustainable Plant Foods

    A Scientific Approach to Alternative Food Sources
    • 1st Edition
    • Sajad Ahmad Wani + 2 more
    • English
    Sustainable Plant Foods: A Scientific Approach to Alternative Food Sources delves into plant-based nutrition and its transformative potential for human health and the environment. By addressing the detrimental effects of animal agriculture on well-being and ecological balance, the book advocates for a shift towards plant-based alternatives. It emphasizes the importance of sustainable diets for improving human health and nutrition while contributing to a more sustainable planet. The book explores new developments and challenges in plant-based alternatives. It covers the nutritional benefits, sensory appeal of underutilized fruits, vegetables, legumes, and strategies for developing clean-label alternatives to eggs, meat, cheese, and milk.

  • Soil Pollution

    From Monitoring to Remediation
    • 2nd Edition
    • Teresa Rocha-Santos + 2 more
    • English
    Soil Pollution: From Monitoring to Remediation, Second Edition provides a comprehensive overview of the causes of soil pollution, distribution, transport, and fate of pollutants and transformation of pollutants in soil and metabolite accumulation. Soil pollution has increased over the last decades and may pose a risk for human and ecological health. The book expands and updates on current knowledge with an increased focus on PFAs and micronanplastics. The new edition also includes a new chapter on the One Health initiative.In this book, researchers and students in soil science will find appropriate and comprehensive information on organic, inorganic, and nanoparticle pollutants in soil, methodologies for their monitoring, and data reporting processes in order to gain adequate insights of pollution problems caused by these pollutants.

  • Comprehensive Toxicology

    • 4th Edition
    • Charlene McQueen
    • English
    Comprehensive Toxicology, Fourth Edition, Fifteen Volume Set continues the legacy that began with the first edition in 1997, serving as an indispensable reference for toxicology researchers. This edition focuses on understanding the mechanisms by which chemicals affect biological systems and cause adverse health effects. Edited by a distinguished editorial board and featuring 400 in-depth contributions from experts around the globe, this comprehensive work spans fifteen volumes and nearly 9,000 pages, covering all major organ systems and general principles of toxicology. This extensively revised edition includes around 30 new chapters on modern testing strategies and novel in vitro models, such as organ-on-a-chip systems.It also explores computational approaches, new risk and safety assessment methods, harmonization, artificial intelligence, and the microbiome. As the most authoritative resource in toxicology, it continues to support researchers, faculty, and students in toxicology, as well as professionals in medical, veterinary, food, environmental, chemical, and pharmaceutical industries and international regulatory agencies.

  • Lipid Analysis in Biology, Health, and Disease

    • 1st Edition
    • Sanjoy K. Bhattacharya
    • English
    Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered.Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.

  • Strategies for Sustainable Shrimp Aquaculture

    • 1st Edition
    • Luis Rafael Martínez-Córdova + 1 more
    • English
    Strategies for Sustainable Shrimp Aquaculture explores the varied impacts of shrimp production and the modern approaches to minimizing those impacts. As demand for shrimp grows not only in the food sector, but also in the pharmaceutical, healthcare, and cosmetics sectors, shrimp farming is among the top-growing global aquaculture industries. Given this growth, much research in recent decades has focused on promoting sustainable scale-up of the industry. This book delves into recent advancements in site selection, nutrition, disease prevention, and production systems.Written by a renowned team of shrimp production experts, this book begins by describing relevant considerations of site selection to maximize use of ecosystem services and minimize effluent impacts on surrounding habitats. Early chapters discuss advances in shrimp nutrition and natural feed using phytoplankton, zooplankton, and microorganisms. The book then turns to genetic tools used to protect against disease, as well as advances in disease detection and outbreak control. Final chapters discuss novel shrimp production systems, including low-density systems, multiphase aquaculture, automatic feeding, inland and boutique farms, aquaponics, polyculture, IMTA, and the best strategies for remediation of affected habitats.

  • Sustainable Valorization of Date Palm By-products and Wastes

    • 1st Edition
    • Sajid Maqsood + 2 more
    • English
    Sustainable Valorization of Date Palm Byproduct and Wastes provides a comprehensive resource on the sustainable valorization of date byproducts and waste. Composed of 13 chapters, this book highlights the various green technologies and processing methods that can be used to extract valuable compounds from these byproducts and convert them into high-value products, such as biofuels, animal feed, and functional food ingredients. Bringing together contributions from leading experts in the field of food science and technology, this title provides a valuable resource for professionals and researchers in the industry, as well as policymakers, entrepreneurs, and students.Date palm is a significant crop in many regions of the world, producing large quantities of byproducts and wastes that are often underutilized or wasted.

  • Machine Learning and Artificial Intelligence in Toxicology and Environmental Health

    • 1st Edition
    • Zhoumeng Lin + 1 more
    • English
    Machine Learning and Artificial Intelligence in Toxicology and Environmental Health introduces the fundamental concepts and principles of machine learning and AI, providing clear explanations on applying these methods to toxicology and environmental health. The book delves into predictions of chemical ADMET properties, development of PBPK and QSAR models, toxicogenomic analysis, and the evaluation of high-throughput in vitro assays. It aims to guide readers in adapting machine learning and AI techniques to various research problems within these fields. Additionally, the text explores ecotoxicology assessment, impacts of air pollution, climate change, food safety, and chemical risk assessment.It includes case studies, hands-on computer exercises, and example codes, making it a comprehensive resource for researchers, academics, students, and industry professionals. The book highlights how AI can enhance risk assessment, predict environmental hazards, and speed up the identification of harmful substances.

  • Advances in Parasitology

    • 1st Edition
    • Volume 128
    • English
    Unveiling the Proteolytic Networks of Parasites, Volume 128 presents a cutting-edge exploration of specific proteases across a spectrum of parasitic organisms. Top researchers in the field conduct multifaceted examinations, shedding light on the distinct roles of these proteases within significant parasite groups, including malaria, trematodes, nematodes, and blood-feeding arthropods. Chapters in this new release An Overview of Fasciola hepatica Protein Glycosylation: Complexity, Mechanisms, Biological Importance, and Future Insights, Angiostrongylus infections in carnivores – biology, epidemiology, clinicopathological aspects, diagnostics and prevention, Changing distribution, diversity and health impact of Echinococcus multilocularis in North America and Europe, and much more.Other chapters cover Gastrointestinal parasitic Protozoa infection of mother and child, and their influence on low birth weight and stunting: a systematic literature review and meta-analysis, Hard to make and hard to take: exploring the current and future barriers to the development and implementation of antipoverty vaccines in Sub-Saharan Africa, and Advances, Challenges, and Applications of Laboratory Culture of Digenean Trematode Parasites.

  • Williams. Tratado de endocrinología

    • 15th Edition
    • Shlomo Melmed + 2 more
    • Spanish
    Revisada y exhaustivamente actualizada, Williams. Tratado de endocrinología, 15.ª edición, sigue siendo la principal fuente de información acreditada acerca de los trastornos del sistema endocrino adulto y pediátrico. Autores y editores de renombre mundial tienden puentes entre la ciencia básica y la información clínica, manteniendo al lector al día de los últimos avances en fármacos, terapias y ensayos clínicos, entre otros muchos temas. Este texto esencial constituye un recurso imprescindible para endocrinólogos, cirujanos endocrinos, ginecólogos, internistas, pediatras y otros profesionales que precisan una cobertura actual y completa de este multifacético campo.

  • Massachusetts General Hospital. Psicofarmacología y Neuroterapéutica

    • 2nd Edition
    • Theodore A. Stern + 2 more
    • Spanish
    Información práctica y específica de uno de los principales hospitales y departamentos de psiquiatría del mundo. La segunda edición de Massachusetts General Hospital. Psicofarmacología y Neuroterapéutica es la guía ideal sobre los más actuales tratamientos psicofarmacológicos y somáticos para enfermedades psiquiátricas y neurológicas. Compuesta por capítulos extraídos principalmente de la tercera edición de Massachusetts General Hospital. Tratado de Psiquiatría Clínica, de Stern et al., la presente obra, exhaustivamente revisada, se centra en los tratamientos psicotrópicos actuales, la terapia electroconvulsiva y la neuroterapéutica, lo que la convierte en una herramienta de ágil consulta, ideal para psiquiatras, psicólogos, internistas y enfermeras.

  • Complicaciones crónicas de la diabetes mellitus. Perspectivas actuales y nuevas claves fisiopatológicas

    • 1st Edition
    • Didac Mauricio + 1 more
    • Spanish
    Entre las complicaciones de la diabetes se incluyen alteraciones patológicas que suelen relacionarse con el sistema vascular y los órganos diana habituales. Sin embargo, también hay complicaciones menos frecuentes, total o parcialmente independientes de la lesión vascular, que suelen pasarse por alto. Este libro ofrece una visión holística de la enfermedad y aborda no solo sus complicaciones habituales, sino también las afecciones menos conocidas y tratadas que se asocian a la diabetes. También se exponen los avances alcanzados en la comprensión de la arquitectura genómica de las complicaciones de la diabetes y cómo se puede utilizar la medicina de precisión para personalizar el tratamiento. Este libro es una obra exhaustiva sobre el tema, dirigida a endocrinólogos, diabetólogos, médicos de atención primaria e investigadores interesados en las complicaciones de la diabetes y en la información más actualizada al respecto.

  • Generative Artificial Intelligence and Ethics for Healthcare

    • 1st Edition
    • Loveleen Gaur + 1 more
    • English
    Generative Artificial Intelligence and Ethics for Healthcare conducts a deep dive into the potential issues and challenges associated with Generative AI applications. The book begins with foundational concepts of generative AI and then explores ethical theories, including specific case studies in healthcare, and concludes with discussions on policy and future implications. Written for healthcare professionals, policymakers, academics and AI developers, by authors who have a thorough understanding of AI and machine learning in the healthcare.

  • Protein Structure Prediction and Analysis

    • 1st Edition
    • Volume 147
    • English
    Protein Structure Prediction and Analysis, Volume 146 offers a comprehensive exploration of the methodologies, tools, and techniques utilized in the prediction and analysis of protein structures. The book delves into the fundamental principles of protein folding, modeling, and computational simulations, providing insights into the intricate process of predicting the three-dimensional structures of proteins. Sections in this new release include coverage of Current approaches for protein structure prediction and design, Protein Modelling, Prediction servers and applications in molecular modelling, Toward accurate in silico prediction of antigen binding affinities in antibody engineering, Molecular Blueprints: Guiding Drug Discovery through Protein Structure Analysis, and much more.Additional sections focus on Protein Structure Prediction Using Dynamic Speciation Evolutionary Algorithm with Problem Information Aggregation, Tau protein structure and dynamics, Tau interacts with G-protein coupled receptors (GPCRs), How to accurately predict nanobody structure: Classical physics-based simulations or deep learning approaches, Medicinal Chemistry-based Novel Therapeutics for Tauopathies in Alzheimer’s Disease, Mapping the Pathogenic Nexus: Gene Overlap and Protein Interaction Networks in Alzheimer's and Breast Cancer as a Precursor to Protein Structure Prediction and Analysis, and much more.

  • Federated Learning in Metaverse Healthcare

    Personalized Medicine and Wellness
    • 1st Edition
    • Shubham Mahajan + 1 more
    • English
    Federated Learning in Metaverse Healthcare: Personalized Medicine and Wellness explores the integration of the metaverse with healthcare, offering immersive experiences and personalized care. The book introduces federated learning, emphasizing its advantages over traditional centralized machine learning in healthcare. It provides a historical context and discusses the technological advancements that led to the emergence of metaverse healthcare. Privacy-preserving methods crucial for protecting sensitive healthcare data within federated learning environments are also examined, underscoring the importance of secure communication protocols. Other important points include the transformation of healthcare delivery through virtual environments, remote consultations, and immersive experiences.The role of telemedicine in facilitating remote diagnostics and consultations via virtual platforms, and the applications of augmented reality wearables for real-time health monitoring and wellness tracking are detailed. Additionally, the book discusses federated learning's ability to deliver personalized treatment plans tailored to individual patient needs, its role in predictive modeling for disease risks and prevention, as well as virtual health coaches offering personalized guidance for wellness management. The challenges and ethical dilemmas of metaverse healthcare and federated learning, along with potential solutions, are also considered.

  • Domestic and Wild Sheep

    Origins, Genetics and Breeding
    • 1st Edition
    • Menghua Li + 1 more
    • English
    The Characterization of Genus Ovis: Genetics, Domestication and Behavior delves into the diverse world of wild and domesticated sheep. This book offers comprehensive information on the genetics, evolution, diversity, behavior, expansion, breeding, and domestication of sheep. It is a detailed characterization of this ecologically and commercially significant genus. Written by experts who have hosted the World Sheep Conference four times, the book is systematically structured into four sections to guide readers through the various Ovis species, their biological characteristics, genetic markers, and their significance to human populations.Furtherm... it offers new insights into the functional genetics of sheep species, their migrations and expansions in connection with human history, and guidance on successful breeding and husbandry. The book is organized for accessibility to student, academic, and professional audiences, making it an indispensable resource for anyone interested in animal evolution, diversity, behavior, and husbandry.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 116
    • English
    Advances in Food and Nutrition Research, Volume 116 presents the most recent developments in food science, focusing on the latest advances in understanding fundamental mechanisms and control solutions for lipid oxidation in meat. It delves into the interactions of cold plasma with food ingredient functionality, examines plant-based milk's health impacts, and critically analyzes the nutritional consequences of emerging processed foods. Additionally, the book addresses the formation and reduction of polycyclic aromatic hydrocarbons in processed foods and explores innovative technologies for meat waste valorization and the detection of bacterial pathogens using biosensors and phage biocontrol.Titles of notable chapters include Lipid Oxidation in Meat: From Fundamental Mechanisms to Latest Control Solutions, Cold Plasma interactions with Food Ingredients Functionality, Current Research on Plant-Based Milk and Impact on Health, Emerging Processed Food and its Nutritional Consequences: A Critical Analysis, and Polycyclic Aromatic Hydrocarbons in Processed Foods: Formation, Occurrence, Analysis and Reduction.

  • Nanotheranostics and Precision Oncology

    • 1st Edition
    • Ramish Riaz + 4 more
    • English
    Nanotheranostics and Precision Oncology delves into the merging fields of cancer research and nanotechnology, offering a thorough review of the latest advancements in precision oncology. It begins with an exploration of cancer biology, illuminating the genetic foundations of oncogenesis alongside the cellular and molecular mechanisms driving cancer progression, metastasis, and drug resistance. This resistance remains the foremost challenge in cancer care. Across 28 chapters, the book addresses precision medicine's role in overcoming drug resistance, the importance of biomarkers, the interpretation of genetic analyses, and the shift toward personalized oncology.In addition, the book examines nanotheranostics' applications and mechanisms in cancer diagnosis and treatment, integrating them with precision oncology. It outlines the design, mechanism, and impact of nanoprecision medicine in cancer management. The final section considers the future of nanotheranostics in precision oncology and the challenges of translating these innovations from research to clinical practice. This comprehensive guide serves students, clinicians, researchers, and the pharmaceutical industry involved in nanomedicine, oncology, molecular biology, and precision medicine.

  • Less-Supervised Segmentation with CNNs

    Scenarios, Models and Optimization
    • 1st Edition
    • Jose Dolz + 2 more
    • English
    Less-Supervised Segmentation with CNNs: Scenarios, Models and Optimization reviews recent progress in deep learning for image segmentation under scenarios with limited supervision, with a focus on medical imaging. The book presents main approaches and state-of-the-art models and includes a broad array of applications in medical image segmentation, including healthcare, oncology, cardiology and neuroimaging. A key objective is to make this mathematical subject accessible to a broad engineering and computing audience by using a large number of intuitive graphical illustrations. The emphasis is on giving conceptual understanding of the methods to foster easier learning.This book is highly suitable for researchers and graduate students in computer vision, machine learning and medical imaging.

  • Animal Models of Disease Part D

    • 1st Edition
    • Volume 197
    • English
    Animal Models of Disease, Part D, Volume 197 in the Methods in Cell Biology series presents significant advancements in understanding disease mechanisms through animal models. This volume features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Handbook of Intervention Science

    From Design to Implementation
    • 1st Edition
    • Laura N.Gitlin + 1 more
    • English
    Handbook of Intervention Science: From Design to Implementation discusses multiple approaches for developing and advancing interventions at the individual, family, community, health system, and policy level. The book focuses on creating interventions suitable for diverse populations from racial, ethnical, geographical, and socioeconomical perspectives. Combining best practices with a practical approach, the book enables readers to advance their intervention research. It covers intervention design, data capture in trials, and evaluation. Decision trees help illustrate when to move forward with an implementation relative to the need for further work.

  • Phytoceuticals in Food for Health and Wellness

    Harnessing Plant Therapeutics
    • 1st Edition
    • Tanmay Sarkar + 2 more
    • English
    Phytoceuticals in Food for Health and Wellness: Harnessing Plant Therapeutics emphasizes the growing interest in the potential health benefits of phytochemicals in wellness and product development by uncovering innate bioactive compounds found in plants. Highlighting the diverse classes of phytochemicals, including flavonoids, carotenoids, polyphenols, antioxidants, and alkaloids, this book explores the sources, chemical structures, and distribution in various plants and what role they play in nutrition and disease prevention. Phytoceutical and phytochemical approaches targeting immunity, obesity, cancer, respiratory, gut, cardiovascular, and eye health, and more, will be discussed. Through traditional and modern extraction methods, Phytoceuticals in Food for Health and Wellness: Harnessing Plant Therapeutics also demonstrates how plant bioactives can be used for fortifying foods for optimal nutrition, innovating in product development, and developing the use of phytochemicals in culinary and food manufacturing applications to maximize favor and extend shelf-life.

  • Biliary Tract Neoplasms

    • 1st Edition
    • Timothy M. Pawlik + 1 more
    • English
    Biliary Tract Neoplasms is a state-of-art reference of the multimodality management of bile duct cancer written by leaders in the field. As targeted therapy and clinical trials in this field are exploding, and the incidence of the disease is increasing, now is the time to address the topic in practical manner. This reference addresses surgical approaches to biliary neoplasms, targeted personalized systemic approaches to biliary neoplasms, and other treatment modalities such as radiotherapy and ablation. It is intended for scientists, researchers, clinicians, practicing surgeons, surgical oncologists, transplant surgeons as well as fellows/residents in the surgical space.The book's translational nature and impact of basic science findings that have informed targeted therapy for biliary neoplasms provide the very latest data on surgery, medical, imaging, and multi-modality care of biliary neoplasm to educate and inform care of this patient population.

  • Plant-Based Drug Discovery

    Unveiling Molecular Targets for Metabolic Conditions
    • 1st Edition
    • Mamta Bisht + 2 more
    • English
    Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

  • Biosensing the Future

    Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part B
    • 1st Edition
    • Volume 216
    • English
    Biosensing the Future: Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring, Part B, Volume 216 covers the rapidly evolving field of biosensors, highlighting their transformative role in modern healthcare, disease monitoring, and personalized medicine. Chapters in this new release include Technologies and emerging trends in wearable biosensing, Implantable biosensors: advancements and applications, Neural implants: restoring function and enhancing quality of life, Ingestible biosensors: monitoring health from within, Ingestible biosensors for monitoring digestive health and nutritional monitoring, Ingestible biosensors for drug delivery monitoring, Artificial intelligence in wearable biosensing: enhancing data analysis and decision-making, and much more.Additional sections cover Wearable Privacy, Ethical and regulatory landscape of wearable, ingestible, and implantable technologies, Characterization of skeletal muscle contraction using a flexible and wearable ultrasonic sensor, Wearable Biosensors for Climate Change and Health Research, and much more. The book systematically explores the integration of biosensing technologies into wearable, ingestible, and implantable devices, offering a multidimensional perspective on their applications, advancements, and future directions.

  • Methodology in Radiomics

    Step-by-step Guide in Radiomics Pipeline
    • 1st Edition
    • Salvatore Claudio Fanni + 3 more
    • English
    Methodology in Radiomics: Step-by-step Guide in Radiomics Pipeline is an essential resource for anyone interested in the rapidly evolving field of radiomics. This comprehensive guide delves into the history and fundamental principles of radiomics, providing readers with a clear understanding of how to implement each step in the radiomic pipeline. The book is designed to bridge the gap between radiomics research and clinical practice, making it an invaluable reference for imaging scientists, researchers, and medical professionals. The book not only covers the basics but also includes troubleshooting techniques to overcome common challenges.It discusses current research and future directions, offering insights into the potential of radiomics in clinical settings. This guide ensures that readers are well-equipped to navigate the complexities of radiomics, fostering a deeper understanding of its applications and advances in medical imaging.

  • Nanomedicine Advancements and Intersectional Perspectives for Women's Health

    • 1st Edition
    • Pankaj Sharma + 1 more
    • English
    Nanomedicine Advancements and Intersectional Perspectives for Women's Health provides detailed insights and innovative treatments that specifically address health issues that women face. It provides valuable information and practical solutions based on scientific evidence providing comprehensive information about nanomedicine advancements specifically targeted towards improving health outcomes. It offers clear explanations of complex medical concepts in nanomedicine in a reader-friendly manner to help bridge the knowledge gap on this topic. By providing clear explanations, real-life examples, and practical insights, it empowers readers with valuable information that can help healthcare professionals make informed decisions working in relevant fields as well as researchers new to the field.

  • Pharmacological Targets in Metabolic Diseases

    Challenges and Opportunities
    • 1st Edition
    • Marcos Roberto de Oliveira
    • English
    Pharmacological Targets in Metabolic Diseases: Challenges and Opportunities is a complete reference on possible drug development targets to be leveraged in therapeutic developments. Covering both signaling pathways and specific proteins, the book presents ways to modulate the molecular and cellular alterations observed in metabolic diseases and disorders through the application of new or classical drugs. The comprehensive coverage starts by providing an overview of metabolic diseases and disorders, biological alterations, and pharmacological targets. This section covers targets at both molecular, and subcellular and cellular levels. The next section in the book is focused on pharmaceutical targeting of organs, including a dedicated chapter to the gut-brain axis. Next comes a thorough review of the current advances in metabolic syndrome research. Section VI is focused on inborn errors of metabolism and is followed by a section devoted to natural molecules and their pharmacological potential to treat these conditions. The Editor introduces next a whole section dedicated to the role of the microbiota in metabolic diseases therapeutics. The following sections cover the impact of aging, nanotechnology, the environment, and finally diagnostic techniques in metabolic diseases and disorders. Pharmacological Targets in Metabolic Diseases: Challenges and Opportunities meet the needs of pharmacology researchers looking for a comprehensive and authoritative source of information on possible therapeutic targets to treat these conditions. Research physicians, nutritionists, pharmacists, and biologists can benefit from the detailed information provided at the different levels of targets identified to treat metabolic diseases and conditions.

  • Advances in Applied Mechanics

    • 1st Edition
    • Volume 62
    • English
    Advances in Applied Mechanics, Volume 62 highlights new advances, with this volume presenting interesting chapters written by an international board of authors. Chapters in this release cover higher order discontinuous Galerkin finite element methods for the contact problems, Anisotropic Recovery-Based Error Estimators and Mesh Adaptation Tailored for Real-Life Engineering Innovation, Adaptive mesh refinement on Cartesian meshes applied to the mixed finite element discretization of the multigroup neutron diffusion equations, and more.Other sections cover a posteriori error analysis for Finite Element approximation of some groundwater models Part I: Linear models, a posteriori error estimates for low frequency electromagnetic computations, and more.

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