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Elsevier

Books in Microbiology and virology

Elsevier's Microbiology & Virology collection provides comprehensive coverage of viruses and microorganisms, addressing their impact on human, animal, and plant health. It includes topics such as prevention, treatment, and research of viral diseases like coronaviruses, flaviviruses, and viral hemorrhagic fevers. The collection delves into fields like Bacteriology, Mycology, and Microbial genetics, focusing on their roles in environmental, agricultural, and health-related contexts. This resource serves as a vital tool for scientists, facilitating the study of viruses and microorganisms and enabling the development of effective strategies for infectious disease prevention, diagnosis, and control.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 56
    • English
    Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. This volume contains 12 comprehensive reviews, including: Uses of Trichoderma spp. to alleviate or remediate soil and water pollution; Lincosamides, chemical structure, biosynthesis, mechanism of action, resistance and applications; Polysaccharide breakdown by anaerobic microogranisms inhabiting the mammalian gut; and Novel aspects of signaling in Streptomyces development.

  • Advances in Applied Microbiology

    Sick Building Syndrome
    • 1st Edition
    • Volume 55
    • English
    Sick Building Syndrome” (SBS) is the term commonly used for symptoms resulting from problems with indoor air quality. This thematic volume in the series examines the microbiological aspects of Sick Building Syndrome, with an emphasis on the mycology of this phenomenon. Focusing on the mechanisms by which Sick Building Syndrome occurs, this book details the current status of technologies for the detection and identification of the causative agents.

  • Infection and Autoimmunity

    • 1st Edition
    • Nancy Agmon-Levin + 2 more
    • English
    Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmuni... association/inductio... Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.

  • Advances in Parasitology

    • 1st Edition
    • Volume 57
    • English
    The Advances in Parasitology series contains in-depth reviews on current topics of interest in contemporary parasitology. It includes medical studies on parasites of major influence, such as trypanosomiasis and scabies, and more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 49
    • English
    First published in 1967, Advances in Microbial Physiology is one of Elsevier's most renowned and acclaimed series. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to publish topical and important reviews, interpreting physiology in its broadest context, to include all material that contributes to our understanding of how microorganisms and their component parts work.

  • Cheese: Chemistry, Physics and Microbiology, Volume 1

    General Aspects
    • 3rd Edition
    • Patrick F. Fox + 3 more
    • English
    The market for cheese as a food ingredient has increased rapidly in recent years and now represents upto approximately 50% of cheese production in some countries. Volume one is entitled General Aspects which will focus on general aspects on the principles of cheese science. This title contains up-to-date reviews of the literature on the chemical, biochemical, microbiological and physico-chemical aspects of cheese in general. Cheese: Chemistry, Physics, and Microbiology Two-Volume Set, 3E is available for purchase as a set, and as well, so are the volumes individually.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 54
    • English
    Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive.

  • Staphylococcus Aureus

    Molecular and Clinical Aspects
    • 1st Edition
    • D A Aldeen + 1 more
    • English
    Staphylococcus aureus is resident in skin and nasal membranes with a formidable pathogenic potential to cause a variety of community and hospital acquired infections. This authoritative survey covers the impact of genome sequences into our understanding of MRSA and MSSA pathogenesis. World specialists from America, Germany, Japan, Sweden and the UK contribute knowledge and experience which will be welcome to researchers, practitioners and postgraduate students of immunology, microbiology, bacteriology and pharmacology worldwide.

  • Microbiology of Waterborne Diseases

    Microbiological Aspects and Risks
    • 1st Edition
    • English
    This comprehensive text describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. It also details the methods for detecting and identifying waterborne microorganisms, the ways in which they are removed from water, and the risks they present to water users. This handbook will serve as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students.

  • Encyclopedia of Endocrine Diseases

    • 1st Edition
    • Luciano Martini
    • English
    The Encyclopedia of Endocrine Diseases is an authoritative reference developed by 16 international experts who recruited the world's top scientists for contributions. This stellar reference work focuses on nearly 500 endocrine diseases addressing everything from acromeglay, diabetes, hypertension, osteoporosis, thyroid disease, Von Hippel-Lindau Disease, unexplained weight loss, to androgen related disorders. This encyclopedia is an essential addition to any library collection written to be accessible for both the clinical and non-clinical reader. Associate Editors include: Eli Y. Adashi, John P. Bilezikian, George P. Chrousos, Junichi Fukata, Julianne Imperato-McGinley, Hiroo Imura, Antonio Liuzzi, Frank L. Moore, Daniel Porte, Jens F. Rehfeld, Ellis Samols, Gustav Schonfeld, Pierre C. Sizonenko, Wilmar M. Wiersinga. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedire...

  • The Flaviviruses: Pathogenesis and Immunity

    • 1st Edition
    • Volume 60
    • English
    Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 53
    • English
    Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive.

  • Advances in Virus Research

    • 1st Edition
    • Volume 62
    • English
    The Advances in Virus Research series covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology.This eclectic volume contains six reviews covering topics relating to plant viruses, evolution of viruses with hosts and cell recognition by viruses.

  • Advances in Parasitology

    • 1st Edition
    • Volume 55
    • English
    First published in 1963, Advances in Parasitology contains comprehensive reviews in all areas of interest in contemporary parasitology. Now edited by J.R. Baker, R. Muller, and D. Rollinson, and supported by an international editorial board, Advances in Parasitology includes medical studies on parasites of major influence, such as typanosomiasis and scabies, and reviews of more traditional areas, such as zoology, taxonomy, and life history. This index volume chronicles the contents of Volumes 28 through 52 and includes a cumulative subject index and contributor list.

  • The Flaviviruses: Detection, Diagnosis and Vaccine Development

    • 1st Edition
    • Volume 61
    • English
    Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research.

  • Cryptosporidium: From Molecules to Disease

    • 1st Edition
    • R.C.A. Thompson + 2 more
    • English
    In the relatively short period since Cryptosporidium was recognised as a human pathogen, and that it could be transmitted in water as well as directly between animals and people, it has been the subject of intense investigations. Its status as an opportunistic pathogen, especially in AIDS patients, and the lack of effective anti-cryptosporidial drugs have served to emphasise the public health importance of this organism. This has to some extent overshadowed the fact that Cryptosporidium is also an important pathogen of domestic animals and wildlife. In recent years, the application of molecular biology and culture techniques have had an enormous impact on our understanding of the aetiological agents of cryptosporidial infections and our ability to study the causative agents in the laboratory. As a consequence, a wealth of information and novel data has been produced during the last 3-4 years, particularly in the areas of taxonomy, biology, pathogenesis, epidemiology - particularly zoonotic and water borne transmission, and treatment.It is thus very timely to bring together in this book the international research community involved to review the major advances in research and identify the important research priorities for the future, thus enabling as wide an audience as possible to benefit from and share in this comprehensive look at Cryptosporidium and cryptosporidiosis.

  • Advances in Antiviral Drug Design

    • 1st Edition
    • Volume 4
    • E. De Clercq
    • English
    The fourth volume of Advances in Antiviral Drug Design is keeping up with the recent progress made in the broad field of antiviral drug research and encompasses six specific directions that have opened new avenues for the treatment of HIV and other virus infections.First, as the introductory chapter, the different new anti-HIV agents that are now in preclinical or clinical development are reviewed by E. De Clercq. This includes new NRTIs, NNRTIs and PIs, but also HIV entry/fusion inhibitors as well as integrase inhibitors, and some of these agents, such as the NRTI emtricitabine [(-)FTC] and the PI atazanavir, may soon be licensed for clinical use.Second, high expectations are vested in the potential therapeutic usefulness of inhibitors of HIV integration, a point of no return in the life cycle of HIV, and this approach is highlighted by D.J. Hazuda and S.D. Young.Third, as all currently available PIs can be described as "peptidomimetic", and, therefore, expected to demonstrate overlapping virus-drug resistance and side effect profiles, it would be interesting to see how a non-peptidic protease inhibitor such as tipranavir behaves, and this is covered by D. Mayers, K. Curry, V. Kohlbrenner and S. McCallister.Fourth, neuraminidase inhibitors such as zanamivir (that has to be inhaled) and oseltamivir (that can be administered via the oral route) have gained a definitive status as antiviral drugs useful for both therapy and prophylaxis of influenza A and B virus infections; as they target a specific influenza viral enzyme, neuraminidase (or sialidase), they may be expected to block newly emerging influenza viruses as well, and the design of neuraminidase inhibitors has received due attention of H. Jin and C.U. Kim.Fifth, while the major current efforts in antiviral drug development have shifted from herpesviruses towards HIV and hepatitis viruses [hepatitis B virus (HBV), hepatitis C virus (HCV)], it is interesting to note that by switching from the classical five-membered sugar or acyclic nucleoside strategy, J. Wang, M. Froeyen and P. Herdewijn have gone "upstream" in designing six-membered carbocyclic nucleosides as potential anti-herpesvirus agents.Sixth, following up on the nucleotide prodrug strategy introduced above under ix, to deliver the biologically active nucleotides inside the cells, C. Meier has elaborated on a particular class of such pronucleotides, namely that of the cyclosaligenyl pronucleotides, an approach that should have far reaching implications for compounds effective against HIV, HBV and other viruses.The six topics covered in this fourth volume of Advances in Antiviral Drug Design are in the front line of the present endeavors towards the design and development of new therapeutic agents for virus infections. They pertain to the combat against three of the most important viral pathogens of current times: HIV, HBV, influenza virus and herpesviruses.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 48
    • English
    First published in 1967, Advances in Microbial Physiology is one of Academic Press's most renowned and acclaimed series. The Editors have always striven to provide a diverse range of top-quality papers on all aspects of microbial physiology. Coverage of 'holistic' topics or whole cell studies such as ion fluxes, stress responses and motility have gone hand-in-hand with detailed biochemical analyses of individual transport systems, electron transport pathways and many aspects of metabolism. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to publish topical and important reviews, interpreting physiology in its broadest context, to include all material that contributes to our understanding of how microorganisms and their component parts work. In 1999, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 5.35, with a half life of 8 years, placing it 5th in the highly competitive category of Microbiology; testimony to the high regard in which it is held.

  • Frontiers in Viral Hepatitis

    • 1st Edition
    • R.F. Schinazi + 2 more
    • English
    Frontiers in Viral Hepatitis provides a compilation of the research from over 40 key opinion leaders in the field of Hepatitis. The book focuses on the latest advances in the search for new, more effective therapeutic options and related topics in viral hepatitis. These include regulatory issues, epidemiology, and emerging viruses; immunology and vaccines; viral hepatitis B and C infections in children; genetics pathology and viral diagnosis; cell systems and animal models; novel therapeutics for hepatitis B and C; resistance and therapeutic strategies in humans; and prevention and treatment options for hepatocellular carcinoma.The breadth of information published in this volume provides insight into current prevention and treatment options. Recent advances in our understanding of the molecular biology, immunology and pathogenesis of hepatitis viruses have accelerated at a remarkable rate, offering a more comprehensive perspective on hepatitis.

  • The Flaviviruses: Structure, Replication and Evolution

    • 1st Edition
    • Volume 59
    • English
    Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Structure, Replication and Evolution is the first volume of The Flaviviruses and presents the latest research covering the conceptual advances on aspects such as the characterization of virus structure, cellular receptors, mechanisms of virus entry, host and viral components of the RNA replicase.

  • The Evolution of Parasitism - A Phylogenetic Perspective

    • 1st Edition
    • Volume 54
    • English
    Parasitology continues to benefit from taking an evolutionary approach to its study. Tree construction, character-mapping, tree-based evolutionary interpretation, and other developments in molecular and morphological phylogenetics have had a profound influence and have shed new light on the very nature of host-parasite relations and their coevolution. Life cycle complexity, parasite ecology and the origins and evolution of parasitism itself are all underpinned by an understanding of phylogeny. The Evolution of Parasitism - A Phylogenetic Perspective aims to bring together a range of articles that exemplifies the phylogenetic approach as applied to various disciplines within parasitology and as applied by parasitologists. Unified by the use of phylogenies, this book tackles a wide variety of parasite-specific biological problems across a diverse range of taxa.

  • Advances in Parasitology

    • 1st Edition
    • Volume 56
    • English
    Advances in Parasitology is a serial containing in-depth reviews on current topics of interest in contemporary parasitology. It includes medical studies on parasites of major influence, such as trypanosomiasis and scabies, and more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications.

  • Viral Hepatitis Molecular Biology Diagnosis and Control

    • 1st Edition
    • Volume 10
    • English
    The last forty years have witnessed the discovery of five human hepatitis viruses: hepatitis virus A, B, C, D, and E, and two related blood-borne viruses: GB virus C and TT virus. Viral Hepatitis provides a comprehensive overview of the latest developments and research studies in human viral hepatitis. Written by leading international scientists in the field, this book covers topics ranging from the history of these viruses to their molecular biology, diagnosis, epidemiology and control. It will be an invaluable reference source for hepatitis researchers, reference and diagnostic laboratories, clinicians, public health officers and graduate and medical students.

  • Antiviral Nucleosides

    Chiral Synthesis and Chemotherapy
    • 1st Edition
    • C.K. Chu
    • English
    • Up-to-date review on the chemistry and biology of nucleosides• Modern synthetic methodology• Comprehensive coverage of antiviral nucleosidesThis book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive reviews on their chiral synthesis.

  • Advances in Parasitology

    • 1st Edition
    • Volume 53
    • English
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Now edited by J.R. Baker, R. Muller, and D. Rollinson, and supported by an international editorial board, Advances in Parasitology includes medical studies on parasites of major influence, such as typanosomiasis and scabies, and reviews of more traditional areas, such as zoology, taxonomy, and life history. Eclectic volumes are supplemented by thematic volumes on such topics as Remote Sensing and Geographical Information Systems in Epidemiology.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 47
    • English
    The Editors of the Advances in Microbial Physiology series have always striven to provide a diverse range of top-quality papers on all aspects of microbial physiology. Coverage of 'holistic' topics or whole cell studies such as ion fluxes, stress responses and motility have gone hand-in-hand with detailed biochemical analyses of individual transport systems, electron transport pathways and many aspects of metabolism. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to publish topical and important reviews, interpreting physiology in its broadest context, to include all material that contributes to our understanding of how microorganisms and their component parts work.

  • Virus Structure

    • 1st Edition
    • Volume 64
    • English
    Virus Structure covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structures and the basic principles that have emerged from these studies. Among the topics covered are Hybrid Vigor, Structural Folds of Viral Proteins, Virus Particle Dynamics, Viral Gemone Organization, Enveloped Viruses and Large Viruses.

  • Viral Vectors for Treating Diseases of the Nervous System

    • 1st Edition
    • Volume 55
    • David S. Latchman
    • English
    Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. Viral Vectors for Treating Disease of the Nervous System describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-associated virus, Herpes Simplex Virus, lentivirus, and other retroviruses. It also discusses the potential application of such viruses in treating brain tumors, Parkinson's disease, and other diseases of the nervous system.

  • Antigenic Variation

    • 1st Edition
    • Alister G. Craig + 1 more
    • English
    The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 52
    • English
    An eclectic volume of topical reviews on all aspects of applied microbiology. It contains 14 comprehensive reviews of current research in applied microbiology.

  • Viral Gastroenteritis

    • 1st Edition
    • Volume 9
    • U. Desselberger + 1 more
    • English
    Viruses are increasingly recognised as the cause of acute gastroenteritis in man, particularly in children. This book provides overviews and updates on current issues relating to basic research, clinical diagnosis, immunology, epidemiology, treatment and prevention of infections with gastroenteritis viruses.Data are presented and interpreted by leading research groups in 33 chapters spread over 6 sections. The book will be of interest to virologists, gut physiologists, immunologists, epidemiologists, vaccinologists, paediatricians and physicians (infectious diseases), and public health physicians. It will also capture the interests of medical and natural science students and postdoctoral scientists at various levels of their careers.

  • Whisky

    Technology, Production and Marketing
    • 1st Edition
    • Graham Stewart + 1 more
    • English
    Whisky: Technology, Production and Marketing explains in technical terms, the science and technology of producing whisky, combined with information from industry experts on successfully marketing the product. World experts in Scotch whisky provide detailed insight into whisky production from the processing of raw materials, to the fermentation, distillation, maturation, blending, production of co-products and quality testing, as well as important information on the methodology used for packaging and marketing whisky in the twenty-first century. No other book covers the entire whisky process from raw material to delivery to the market in such a comprehensive manner and with such a high level of technical detail.

  • Handbook of Secondary Fungal Metabolites, 3-Volume Set

    • 1st Edition
    • Richard J. Cole + 2 more
    • English
    This three-volume set is a desirable reference for a wide range of specialists who study secondary fungal metabolites ranging from pharmaceutical house researchers, agricultural researchers, those involved in food and feed control regulation, and veterinary researchers. It discusses in depth the molecular formula of, the molecular weights of, and fungal/plant source indexes of secondary fungal metabolites.

  • Perspectives in Medical Virology

    • 1st Edition
    • Volume 1
    • Brian Evans
    • English

  • Molecular Microbiology Laboratory

    A Writing-Intensive Course
    • 1st Edition
    • Walt Ream + 3 more
    • English
    Molecular Microbiology Laboratory is designed to teach molecular biology techniques to upper level undergraduates majoring in the life sciences. An extremely detailed lab preparation manual for teaching assistants accompanies the lab book and contains a general discussion of scientific writing and critical reading, as well as detailed instructions for preparation and peer review of lab reports. Each experimental unit is accompanied by a number of additional writing exercises based upon primary journal articles. The studies in these articles employ the techniques that the students are learning in the lab exercises, which reinforces their understanding of the material. These are techniques that students in any biological science will need to know, making this manual applicable to any life science curriculum.

  • Advances in Parasitology

    • 1st Edition
    • Volume 52
    • English
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Now edited by J.R. Baker (Royal School of Tropical Medicine and Hygiene, UK), R. Muller (International Institute of Parasitology, UK) and D. Rollinson (The Natural History Museum, UK), supported by an international Editorial Board, Advances in Parasitology includes medical studies on parasites of major influence, such as typanosomiasis and scabies, and reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on such topics as Remote Sensing and Geographical Information Systems in Epidemiology.

  • Functional Microbial Genomics

    • 1st Edition
    • Volume 33
    • English
    Functional Microbial Genomics, edited by two leading experts in the field, provides the researcher with an up-to-date collection of articles on post-genome technologies central to studying the function of microorganisms.Since the release of the first complete genome sequence of a free-living organism in 1995, over 100 microbial genomes have been completely sequenced. The advent of new technologies for post-genomic analyses has allowed the rapid exploitation of this genome sequence information, heralding a golden era in microbial research. Functional Microbial Genomics provides in-depth accounts from scientists working with these new technologies explaining both the techniques and the ways in which they have been applied to the study of gene function in different microbial species.Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research.

  • Bacterial Pathogenesis, Part C: Identification, Regulation and Function of Virulence Factors

    • 1st Edition
    • Volume 358
    • English
    The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences.

  • Histidine Kinases in Signal Transduction

    • 1st Edition
    • Masayori Inouye + 1 more
    • English
    Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions. Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes. An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool.

  • Foodborne Diseases

    • 2nd Edition
    • Dean O. Cliver + 1 more
    • English
    This second edition of Foodborne Diseases deals with four aspects of the topic: principles, infections, intoxications, and prevention. In addition to outlining the various infections like Salmonella, some of the other topics covered are: disease processes in foodborne illness; natural toxicants; seafood toxins; microbiology of food preservation and sanitation; and organizing a safe food supply system. Chapters are clearly illustrated, and this latest edition contains an increased number of diagrams and tables.It also adopts a more global view, and the list of contributors is more international. Extensively indexed and easy-to-read, this work should serve as a reference to anyone with concerns about the global impact of foodborne diseases.

  • Aquatic Ecosystems: Interactivity of Dissolved Organic Matter

    • 1st Edition
    • English
    Aquatic Ecosystems explains the interplay between various movements of matter and energy through ecosystems mediated by Dissolved Organic Matter. This book provides information on how much DOM there is in a particular aquatic ecosystem and where it originates. It explains whether the DOM composition varies from time to time and place to place. It also details how DOM becomes incorporated into microbial food webs, and gives a better, clarifying, understanding to its significance of DOM.

  • Human Papilloma Viruses

    • 1st Edition
    • Volume 8
    • D.J. McCance
    • English
    This book describes up-to-date information on the pathogenesis and molecular biology of human papillomaviruses and describes the mechanistic role of the viruses in epithelial cancers. Included in the book are chapters on the epidemiology of human papillomaviruses, the factors that control replication and transcription and the viral proteins, which are involved in modulating the biology of the host cell leading to cancer. Details of the immune response to the viruses and potential vaccine strategies are discussed.

  • Recent Advances in Nucleosides: Chemistry and Chemotherapy

    • 1st Edition
    • C.K. Chu
    • English
    The book covers up-to-date information on nucleosides and antiviral chemotherapy contributed by the world experts in the field of nucleoside. This book is the result of a meeting honoring Dr. Jack J. Fox, who was one of the pioneers in nucleoside chemistry and chemotherapy. This book consists of 15 excellent chapters in the area, which include topics from recent synthetic methodologies, nucleoside kinase implicated in chemotherapy and drug design, excellent reviews on antiviral agents, nucleoside metabolism/mode of action in parasites, new compounds under clinical and pre-clinical trials, IMPDH inhibitors to review on nucleoside prodrugs.

  • E. coli

    Genomics, Evolution and Pathogenesis
    • 1st Edition
    • Michael Donnenberg
    • English
    Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods — such as undercooked meat and unpasteurized fruit juice — and has attracts much attention when serious outbreaks occur. E. coli is capable of causing a wide variety of diseases — from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness. Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 51
    • Allen I. Laskin + 2 more
    • English
    Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive.

  • Advances in Parasitology

    • 1st Edition
    • Volume 51
    • John R. Baker + 2 more
    • English
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Now edited by J.R. Baker (Royal School of Tropical Medicine and Hygiene, UK), R. Muller (International Institute of Parasitology, UK) and D. Rollinson (The Natural History Museum, UK), supported by an international Editorial Board, Advances in Parasitology includes medical studies on parasites of major influence, such as typanosomiasis and scabies, and reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on such topics as Remote Sensing and Geographical Information Systems in Epidemiology. In 1999, the Institute for Scientific Information released figures showing that Advances in Parasitology has an Impact Factor of 4.913, placing it 2nd in the highly competitive category of Parasitology.

  • Influenza

    • 1st Edition
    • Volume 7
    • C.W. Potter
    • English
    Since the influenza virus was first isolated in the laboratory some 70 years ago, the disease has been the subject of intense study, and our knowledge has escalated as the newer techniques of medicine and science have made further advances possible. At the present time, our information of the disease and the virus that causes it is probably more detailed than for any other virus infection, perhaps excluding the human immunodeficiency virus. The subject of influenza divides itself into a number of specialities, and such is the pace of research and the depth of our knowledge, that workers in one area may have little understanding of the advances made in others.This volume of Perspectives in Medical Virology has enlisted twelve internationally recognised researchers on specific aspects on the subject of influenza to write a summary of the important developments in the past and offer their views on the problems that remain to be addressed. It is hoped that their emphasis, reservations and projections are of value to future research, and offer directions for a better understanding of the virus, the disease it causes, the production of vaccines and the development of therapeutic agents so that at some date in the future this infection can be brought under control.

  • Advances in Virus Research

    • 1st Edition
    • Volume 58
    • English
    This latest volume in the Advances in Virus Research series presents articles on topics such as the role of lipid rafts in virus assembly and budding; novel vaccine strategies; treatment of arenavirus infections; the evaluation of drug resistance in HIV infection; perspectives on polydnavirus origin and evolution; bateriophage 29 DNA packaging; the potential of plant viral vectors and transgenic plants for subunit vaccine production; and the interaction of orthopoxviruses with interferon-treated cultured cells. This timely and informative compilation of articles will be of interest to researchers in the fields of virology, immunology, microbiology, and plant science.

  • Bioenergetics

    • 3rd Edition
    • David G. Nicholls + 1 more
    • English
    This new edition of Bioenergetics presents a clear and up-to-date explanation of the chemiosmotic theory and covers mitochondria, bacteria, and chloroplasts. It takes account of the many newly determined structures, such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction. This edition includes additional color figures of protein structures and many newly drawn illustrations designed to enable the reader to grasp the fundamental insights that are derived from knowing the structure. Every chapter has been extensively revised and updated and a new chapter on the study of the bioenergetics of mitochondria in the intact cell is included to satisfy the enormous interest in this topic. Written for students and researchers alike, this book is the most current text on the chemiosmotic theory and membrane bioenergetics available.

  • Viruses and Liver Cancer

    • 1st Edition
    • Volume 6
    • E. Tabor
    • English
    Hepatocellular carcinoma (HCC) is one of the most important complications of chronic viral hepatitis. It usually results in a fatal outcome if not discovered in its earliest stages. Its close association with the hepatitis B and C viruses makes it one of the first human cancers for which there is strong evidence of a viral cause. For this reason it provides a model for studying viral carcinogenesis in humans.In some countries, HCC is one of the most common tumors of adult men. In addition, there is evidence that the incidence of this cancer has doubled in the past 15 to 20 years in many countries, and the incidence has doubled every 20 years for the past half century in Japan. In some studies, the increase has been shown to be due primarily to cases associated with HCV infection.Molecular studies of HCC show that mutations in oncogenes, in various cellular repair pathways, and in tumor suppressor genes together appear to contribute to the development of this cancer. In HCCs associated with hepatitis B virus, the virus itself can interact with tumor suppressor proteins and other cellular signals in ways that probably permit HCC to develop even when there are no mutations in the genes for these signals.This work discusses the latest concepts in molecular biology and the study of HCC which have led to dramatic breakthroughs in our understanding of how it develops.

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