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Elsevier

Books in Virology

Offering comprehensive coverage of virus structure, replication, and immune response, this portfolio supports virologists, clinicians, and researchers. It features emerging viruses, vaccine development, and antiviral therapies, addressing global challenges such as pandemics, viral resistance, and zoonotic transmission, fostering innovations in disease prevention and control.

  • Cytomegalovirus

    From Biology to Clinical Aspects
    • 1st Edition
    • Adriana Calderaro
    • English
    Cytomegalovirus: From Biology to Clinical Aspects delves into the intricate world of Cytomegalovirus (CMV), offering a comprehensive exploration of its fundamental biology and clinical implications. This book serves as an essential resource for understanding CMV from its epidemiology and infection routes to its pathogenesis and immunity. It addresses the virus’s impact on various demographics and provides insights into diagnostic and treatment strategies. The book covers critical aspects such as vulnerability indicators, cellular damage, laboratory detection, and management strategies. It stands out as a valuable reference for current clinical practices and fundamental scientific knowledge on CMV, offering methods to interpret diagnostic results.

  • Viruses

    Molecular Biology, Host Interactions, and Applications to Biotechnology
    • 2nd Edition
    • Paula Tennant + 2 more
    • English
    Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology, Second Edition provides an update on recent developments and perspectives, including coverage on the history of viruses, their structure, the organization of their genomes, and strategies in replication and expression. It emphasizes their diversity and versatility, how they cause disease, and how their human, animal, and plant hosts react. Sections also explore the beneficial aspects of viruses and how they can be utilized as tools and targets for biotechnological applications. This edition will appeal to a wide audience, including academics, researchers, and students studying the molecular biology and applications of viruses.Advances in technologies and enhanced surveillance have facilitated the monitoring of virus evolution, transmission dynamics, and pathogenesis. Coupled with the experiences of the COVID-19 pandemic, we have a better understanding of the interconnectedness of human, animal, and environmental health and the impact viruses have on society and the economy. This new release updates on many critical aspects of viruses and recent research.

  • Viral Hemorrhagic Fevers

    Epidemiology, Pathogenesis, Management, and Preparedness
    • 1st Edition
    • Agiesh Kumar Balakrishna Pillai + 2 more
    • English
    Viral Hemorrhagic Fevers: Epidemiology, Pathogenesis, Management, and Preparedness covers the causative agents, outbreaks, and clinical management of emerging and re-emerging viral hemorrhagic fevers. Coverage includes a range of topics from basic virology, epidemiology, and disease pathogenesis of emerging and re-emerging hemorrhagic fever viruses. The book examines host-virus interactions, immune pathogenesis, and recent trends in disease diagnostics. It also covers current state-of-the-art in understanding molecular mechanisms of disease pathogenesis, the potential of molecular markers for disease prognostics, early prediction of disease outcome, advancements in diagnosis and drug development, and strategies in pandemic preparation, mitigation, and responses in public health security.With chapters written and compiled by a team of well-known virologists, clinicians as well as regulatory and public health experts. This book is a comprehensive guide that will help users understand the transmission, pathogenesis, and clinical management of emerging and re-emerging viruses causing hemorrhagic diseases.

  • Leveraging Viruses for the Treatment of Viral Diseases and Cancer

    Improving Host Fitness Through Virus-Host Genetic Combinations
    • 1st Edition
    • Tibor Bakacs
    • English
    Leveraging Viruses for the Treatment of Viral Diseases and Cancer: Improving Host Fitness by Combinations of Virus and Host Genes gives a comprehensive overview on the impact of using naturally or intentionally attenuated viruses - which are apathogenic to people - to control viral diseases and cancer. It examines the potential of exploiting, developing, and using apathogenic viruses as therapeutic tools. Sections cover the COVID-19 pandemic and the need for a post-Infection Plan B to combat SARS-CoV-2 infections as gaps in testing and vaccination create the perfect conditions for a new variant of concern to emerge.More generally, the book also provides specific examples of the use of apathogenic viruses to treat other infectious diseases. It discusses the process of manufacturing viral therapies and how infectious disease treatments can be repurposed to improve other therapies like for cancer. With contribution from an international group of contributors, Leveraging Viruses for the Treatment of Viral Diseases and Cancer is useful references for those engages in study and development of infectious diseases and ways to combat them.

  • Rabies

    Scientific Basis of the Disease and Its Management
    • 5th Edition
    • Alan C. Jackson + 1 more
    • English
    Rabies: Scientific Basis of the Disease and its Management, Fifth Edition is an authoritative reference that delves into the virological, clinical, and public health facets of rabies. This new edition provides insights into the molecular virology, pathogenesis, diagnosis, immunology, treatment, epidemiology, and public health strategies for managing rabies. It also includes discussions on the One Health approach to rabies, global implications, and setbacks due to the COVID-19 pandemic. Furthermore, the book serves as an essential resource for physicians, veterinarians, public health advisors, epidemiologists, and research scientists, offering current information on diagnosing, treating, controlling, and preventing this deadly infectious disease.

  • Adenoviral Vectors for Gene Therapy

    • 3rd Edition
    • David T. Curiel + 1 more
    • English
    Adenoviral Vectors for Gene Therapy, Third Edition, provides detailed, comprehensive coverage of gene delivery vehicles based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, as platforms for gene therapy and gene editing, as well as for oncology approaches, making them class leading agents in the gene-advanced therapies arena.The fully updated and expanded third edition covers the basic biology of adenoviruses and highlights the potential use of adenoviral vectors for the treatment of disease, including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for veterinary applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine applications, and oncolytic adenoviruses for antitumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

  • Neuropsychiatric Complications of HIV

    A Challenging Health Concern
    • 1st Edition
    • Anchal Singh
    • English
    Neuropsychiatric Complications of HIV: A Challenging Health Concern examines these neuropsychiatric complications prevalent in those who are HIV positive, providing clinical correlation, translational significance, and details guides to neurocognitive assessment, brain imaging, and related neuropharmacology. Written for clinicians, researchers, and students working with HIV and AIDS, the book begins with the biology of HIV, a complete look at available ARTs and antibodies, as well as diagnostics tools for HIV.It continues on to the epidemiology of NeuroAIDs and the manifestations of it—cognitive deficits, dementia, depression, agitation, psychosis, and cognitive slowing.

  • Understanding the Pandemic

    Pathophysiology, Transmission, and Treatment of COVID-19
    • 1st Edition
    • Shampa Chatterjee + 7 more
    • English
    Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of COVID-19 aims to cover all aspects of COVID-19 infection from the virus, transmission, pathogenesis, immune-inflammation response, systemic injury, organ damage, associated factors, and comorbidities that drive mortality. Organized into ten sections, the book aims to provide a comprehensive examination of the impact of COVID-19. The book begins a review of coronaviruses, their structure and mechanism of action. The book goes on to discuss the immune response to the virus and its effect on various organs. It examines clinical cases based on an observations and postmortem studies.Other topics include the long-term effects of COVD-19, vaccines, and public health response.

  • Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques

    • 1st Edition
    • Mohammad Sufian Badar + 4 more
    • English
    Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques offers new insights and demonstrates how machine learning (ML), artificial intelligence (AI), and (Internet of Things (IoT) can be used to diagnose and fight COVID-19 infection. Sections also discuss the challenges we face in using these technologies. Chapters cover pathogenesis, transmission, diagnosis, and treatment strategies for COVID-19, Artificial Intelligence and Machine Learning, and Blockchain /IoT Blockchain technology, examining how AI can be applied as a tool for detection and containment of the spread of COVID-19, and on the socioeconomic and educational post-pandemic impacts of the disease.This is a multidisciplinary resource for those engaged in researching COVID-19 and how emerging technologies are being used as tools for detection, transmission and treatment strategies.

  • Aquaculture Virology

    • 2nd Edition
    • Frederick S.B. Kibenge + 1 more
    • English
    In 2018, the International Committee on Taxonomy of Viruses (ICTV) approved significant changes leading to a comprehensive taxonomic scheme, allowing the global organization of the virus world (also known as virus megataxonomy). Aquaculture Virology, Second Edition updates the current knowledge on aquatic animal viruses so that all virus families (including those with many newly discovered aquatic animal viruses and those with previously unclassified aquatic animal viruses that have been now assigned) are available under one cover, increasing the number of book chapters from 37 in the first edition to 44 chapters in the second edition. The aims, philosophy, target audience, focus, and format of this second edition of Aquaculture Virology remain unchanged. Like the first edition, this book is a systematic and concise resource useful to anyone involved with or looking to move into aquaculture and fisheries. Clinical veterinarians, aquaculture disease practitioners, biologists, farmers, and all those in industry, government, or academia interested in aquatic animal virology will find this book extremely useful.

  • Pathogenic Viruses and Armamentarium Design

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Pathogenic Viruses and Armamentarium Design covers the latest developments in viral target elucidation and viral control using wet and dry lab strategies. The control and combat strategies and their implementation compiled in this book are invaluable in aiding the understanding of viral disease progression and for designing new strategies against existing and evolving viruses.This important resource is a comprehensive compilation of antiviral approaches designed and devised using computational and other laboratory techniques. This book is a useful reference for scientists, researchers, industry professionals, advanced students, and postgraduates in virology, biotechnology, infection biology, biochemistry, and pharmaceutical sciences who engaged in the study of pathogenic virus and the development of prophylactics and therapeutics against viral infection.

  • Management, Body Systems, and Case Studies in COVID-19

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    Management, Body Systems, and Case Studies in COVID-19 describes the assessment and treatment of patients infected with the novel coronavirus that causes the varied symptoms of COVID-19. Detailing this multisystem disease and the organs and tissues affected, this volume features chapters on several body systems. Conditions affecting the respiratory, hematological, hepatobiliary, renal, gastrointestinal, nervous, musculoskeletal, and cardiovascular systems are addressed. The fundamental role of telemedicine during the pandemic is also discussed. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

  • Features, Transmission, Detection, and Case Studies in COVID-19

    • 1st Edition
    • Rajkumar Rajendram + 2 more
    • English
    Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

  • Linking Neuroscience and Behavior in COVID-19

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    Linking Neuroscience and Behavior in COVID-19 examines the effect of both the virus and the pandemic on behavior and mental health. Chapters look at the burden of the COVID-19 pandemic on those with pre-existing conditions, including Parkinson’s disease and multiple sclerosis. The ongoing consequences of the pandemic on the mental health of the broad populace are discussed. As well as the neurological effects of the virus itself, chapters discuss psychological concerns including depression and anxiety. Finally, the chapters also include aspects relevant to managing care and the treatment of conditions. A broad range of conditions preceding, caused by, or emerging for the first time during the pandemic are also detailed.

  • International and Life Course Aspects of COVID-19

    • 1st Edition
    • Rajkumar Rajendram + 2 more
    • English
    International and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide.

  • Thematic Approaches to COVID-19

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.Linking Neuroscience and Behavior in COVID-19 examines the effect of both the virus and the pandemic on behavior and mental health. Chapters look at the burden of the COVID-19 pandemic on those with pre-existing conditions, including Parkinson's disease and multiple sclerosis. The ongoing consequences of the pandemic on the mental health of the broad populace are discussed. As well as the neurological effects of the virus itself, chapters discuss psychological concerns including depression and anxiety. Finally, the chapters also include aspects relevant to managing care and the treatment of conditions. A broad range of conditions preceding, caused by, or emerging for the first time during the pandemic are also detailed.Internation... and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide.Management... Body Systems, and Case Studies in COVID-19 describes the assessment and treatment of patients infected with the novel coronavirus that causes the varied symptoms of COVID-19. Detailing this multisystem disease and the organs and tissues affected, this volume features chapters on several body systems. Conditions affecting the respiratory, hematological, hepatobiliary, renal, gastrointestinal, nervous, musculoskeletal, and cardiovascular systems are addressed. The fundamental role of telemedicine during the pandemic is also discussed. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

  • Bioreactor Design Concepts for Viral Vaccine Production

    • 1st Edition
    • Surajbhan Sevda + 1 more
    • English
    Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production.

  • Fundamentals of Viroid Biology

    • 1st Edition
    • Charith Raj Adkar-Purushothama + 5 more
    • English
    Fundamentals of Viroid Biology provides a comprehensive introduction to emerging research on viroids and their biology. The book is organized into three parts, with sections that discuss historical perspectives as well as information on classifications, structure, life cycle and replication and viroid movement. The book goes on to discuss viroid diseases and their geographic distributions across Asia, Europe, Africa, Australia, North and South America. Viroid pathogenesis and viroid-host interaction rounds out the coverage which includes viroid associated disease symptoms and viroid regions associated and viroid-host protein and translations. Detection and disease control strategies are also covered. Contributed by an international group of renown contributors in viroid research, this book is a useful introductory reference to advanced undergraduates and graduate and postgraduate students. It is also ideal for early career researchers and scientists engaged in the study of viroid biology, virology, plant virology and microbiology.

  • Viral Diseases of Field and Horticultural Crops

    • 1st Edition
    • L. P. Awasthi
    • English
    Viral Diseases of Field and Horticultural Crops details the fundamental and applied aspects of the viral diseases of field and horticultural crops. The book opens with a historical introduction to plant virology, important plant virologists, and landmarks. It continues with systematic coverage of viral diseases, their economic significance, disease symptoms, host range, mode of transmission, diagnostic techniques, geographic distribution, epidemiology, yield losses, and control and management of the disease. Contributions from an international group of virologists with a wide range of academic, research, professional, and specialized backgrounds in plant virology makes Viral Diseases of Field and Horticultural Crops a comprehensive and must-have resource for those engaged in the study and research of plant virology, microbiology, and plant pathology particularly viral diseases and their impact on field and horticultural crops.

  • Global Perspectives on the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans

    Zoonotic, Epizootic, and Anthropogenic Viral Pathogens
    • 1st Edition
    • Jayashree Seema Nandi
    • English
    Global Perspectives of the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans: Zoonotic, Epizootic, and Anthropogenic Transmission Viral Pathogens elaborates on the current knowledge surrounding the transmission of zoonotic RNA viruses from different wild animal species to humans, including updates on the reverse transmission of pathogens to humans across the globe, with coverage of rodents, pigs, birds and primates. This reference goes beyond the phenomena occurring in African and American regions to provide further study of zoonotic pathogens from the entire world, including various parts of Asia such as India. The book comprehensively covers new knowledge on many diverse wild primate species for a global perspective on the phenomena of cross-species transmissions of pathogenic RNA viruses. Against the backdrop of the current global Covid-19 pandemic, this reference helps solve the problem of incomplete knowledge on global epidemiology of zoonotic RNA viruses. RNA viruses have pandemic, epidemic and epizootic potentials caused by Influenza viruses, Avian Influenza viruses, and other infectious viruses.

  • Plant RNA Viruses

    Molecular Pathogenesis and Management
    • 1st Edition
    • Rajarshi Kumar Gaur + 2 more
    • English
    Plant RNA Viruses: Molecular Pathogenesis and Management provides wide-ranging coverage on the recognition and signaling events between plants and RNA viruses. The book examines the molecular biology of signaling, host-virus interaction, RNA virus diversity, and how plants and cellular pathogens interact. Sections cover Virus Diversity and Diagnosis, Virus-Host Interactions and Virus Management. Specific chapters discuss classification and nomenclature of viruses, detail the molecular characteristics of viral genomes, highlight the viral manipulation of cellular key regulatory systems for successful virus infection, and discuss the movement of plant viruses into plant cells. Additional topics include RNA plant viruses and host interaction, detection and diversity of plant RNA viruses, and strategies for combating and management of plant viruses. With contributions from an international group of experts, the book is a comprehensive reference for those in research, academia, industry and anybody engaging in the study of plant viruses at the molecular level.

  • Smart Nanomaterials to Combat the Spread of Viral Infections

    Advanced Strategies for the Prevention of Viral Infections
    • 1st Edition
    • Raju Khan + 1 more
    • English
    Smart Nanomaterials to Combat the Spread of Viral Infections comprises nanotechnology-based approaches with detailed preventive and treatment methodology for enabling their application in antiviral systems. This book discusses the role of metal nanoparticles in the treatment of and prevention of viral infections and nanotechnology advancements in antiviral coatings to combat affected surfaces. It also covers the use of nanomaterials for the efficient intracellular delivery of antiviral agents to disinfect and treat viral infections. This is a timely coverage of how nanotechnologies and materials as well as the utilization of artificial intelligence and Internet of things–based smart nano-systems are used to control and manage viral infections during the COVID-19 pandemic. Advances in smart research and future antimicrobial applications round out the book. This book provides a comprehensive overview of smart nanomaterials and advanced nano-system applications to researchers and academics in virology, microbiology, chemistry, material science, nanotechnology, and biotechnology as well as those in industries interested in their virucidal properties to prevent viral infections.

  • Computational Modeling of Infectious Disease

    With Applications in Python
    • 1st Edition
    • Chris von Csefalvay
    • English
    Computational Modeling of Infectious Disease: With Applications in Python provides an illustrated compendium of tools and tactics for analyzing infectious diseases using cutting-edge computational methods. From simple S(E)IR models, and through time series analysis and geospatial models, this book is both a guided tour through the computational analysis of infectious diseases and a quick-reference manual. Chapters are accompanied by extensive practical examples in Python, illustrating applications from start to finish. This book is designed for researchers and practicing infectious disease forecasters, modelers, data scientists, and those who wish to learn more about analysis of infectious disease processes in the real world.

  • Cann's Principles of Molecular Virology

    • 7th Edition
    • Edward P. Rybicki
    • English
    **Selected for 2026 Doody's Core Titles as an Essential Purchase in Microbiology**Cann's Principles of Molecular Virology, Seventh Edition provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. The new edition provides the history of virology and the fundamentals of the molecular basis of how viruses work. It discusses the interactions which control the structure of virus particles, the ways viruses infect cells, how viruses replicate themselves, and the consequences and pathogenesis of virus infection for host organisms. This fully updated edition also reflects advances made in the field and includes new content on phage therapy, CRISPR as a phage defense / offense system, new ideas about evolution, and giant viruses. With the addition of ancillary resources, Principles of Molecular Virology, Seventh Edition is an essential foundational reference for academics, graduate students, and advance undergraduates in virology, molecular biology, and microbiology as well as researchers entering virology, infectious disease, and immunology research.

  • Viral Infections and Antiviral Therapies

    • 1st Edition
    • Amal Kumar Dhara + 1 more
    • English
    Viral Infections and Antiviral Therapies provides comprehensive coverage of viral infections and their transmission. Coverage includes antiviral agents, therapeutics, their mechanisms and treatment strategies. The book is organized into four sections, including an introduction to antiviral therapies, viral infections and their transmission, antiviral agents and therapeutics, and a market overview and future developments. The chapters in each section of the book discuss various key topics that are contributed to by an international group of leading experts.

  • Viruses and Climate Change

    • 1st Edition
    • Volume 114
    • English
    Viruses and Climate Change, Volume 114 in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters on carbon-cycle and vector-borne viruses. Chapters in this release cover Viruses in the carbon cycle and the impacts on climate change and Climate change and mosquito-borne virus transmission.

  • Pathogenic Coronaviruses of Humans and Animals

    SARS, MERS, COVID-19, and Animal Coronaviruses with Zoonotic Potential
    • 1st Edition
    • Lisa A. Beltz
    • English
    Pathogenic Coronaviruses of Humans and Animals: SARS, MERS, COVID-19, and Animal Coronaviruses with Zoonotic Potential provides relevant information about common human coronaviruses that may mutate to increase their virulence. The addition of animal coronaviruses allows awareness of not only the potential of zoonotic transmission of coronaviruses from wild animals such as bats and rodents, but also from domestic agricultural and companion animals. The book opens with an introductory chapter on viruses, the immune system, coronaviruses, and their classifications, prevention and protection. Sections also cover history, disease, causative virus, immune response, diagnosis, treatment, prevention and surveillance. The book's remaining chapters discuss coronaviruses with possible zoonotic transmission of domestic, semi-domestic animals and companion animals. It concludes with future perspectives of coronavirus mutations, modeling, protective measures and a discussion around pandemics and infectious diseases from around the globe.

  • Oncogenic Viruses Volume 2

    Medical Applications of Viral Oncology Research
    • 1st Edition
    • Moulay Mustapha Ennaji
    • English
    Oncogenic Viruses: Medical Applications of Viral Oncology Research, Volume Two builds on the introductory overview of Volume One, Oncogenic Viruses: Fundamentals of Oncogenic Viruses. It looks at recent advances and medical application of research studies on oncoviruses, including examining oncoviruses on a molecular level, covers diagnostic and prognostic viral biomarkers and identifying biomarkers in specific human cancers, and delves into prevention, treatment and the future of cancer therapy of oncoviruses, antiviral activities and vaccination strategies. Advanced topics and the future direction of oncovirology round out the book. This book is a comprehensive reference for researchers and practitioners engaged in learning more about the role of oncogenic viruses in the pathogenesis of human cancers and how that information can be applied to identify strategies for prevention and treatment.

  • Oncogenic Viruses Volume 1

    Fundamentals of Oncoviruses
    • 1st Edition
    • Moulay Mustapha Ennaji
    • English
    Oncogenic Viruses: Fundamentals of Oncoviruses provides an overview of the history of human oncoviruses, how to discover and define an oncovirus, how viruses cause cancer in general, their oncogenic mechanisms and epidemiology, and the cancer biology of oncoviruses. The book is organized into five main parts that include history and discovery of virus-tumor complications, taxonomy and classification of oncoviruses, oncoviruses around the world, including epidemiology statistics and current methods. Finally, the book looks at the molecular epidemiology of DNA and RNA viruses and their role in the pathogenesis of human cancers.

  • Immunopathology, Diagnosis and Treatment of HPV induced Malignancies

    • 1st Edition
    • Prashant Khare + 1 more
    • English
    Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explains the deep knowledge about molecular mechanism in HPV pathogenesis and recent advanced tools applied in the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other malignancies.

  • Nanotechnological Applications in Virology

    • 1st Edition
    • Mahendra Rai + 1 more
    • English
    Nanotechnological Applications in Virology explores the use of nanoparticles-based technologies to fight against viruses, also discussing the use of nanoparticles in the preparation of nano masks and as sanitizing agents. The role of nanotechnology against HIV, Hepatitis, Influenza, Herpes, Ebola and Zika using rapid detection and diagnostic techniques is included, as is a brief description of SARS, MERS, the novel Coronavirus, and recent advancements in its treatment process. Other sections cover the formulation of novel nano-vaccines for the treatment and control of viral infections like HIV, Hepatitis and COVID-19. Included toxicological studies of nanoparticles provide readers with a brief overview on global scenarios regarding viral infections. Nanotechnology is the present age technology, with wide usage in different areas of medical science, including drug delivery, gene therapy, antimicrobials, biosensors and bio-labelling. Nanoparticles play a competent role as an anti-infection agent and thus act as efficient antiviral agents.

  • Mathematical Analysis of Infectious Diseases

    • 1st Edition
    • Praveen Agarwal + 2 more
    • English
    Mathematical Analysis of Infectious Diseases updates on the mathematical and epidemiological analysis of infectious diseases. Epidemic mathematical modeling and analysis is important, not only to understand disease progression, but also to provide predictions about the evolution of disease. One of the main focuses of the book is the transmission dynamics of the infectious diseases like COVID-19 and the intervention strategies. It also discusses optimal control strategies like vaccination and plasma transfusion and their potential effectiveness on infections using compartmental and mathematical models in epidemiology like SI, SIR, SICA, and SEIR. The book also covers topics like: biodynamic hypothesis and its application for the mathematical modeling of biological growth and the analysis of infectious diseases, mathematical modeling and analysis of diagnosis rate effects and prediction of viruses, data-driven graphical analysis of epidemic trends, dynamic simulation and scenario analysis of the spread of diseases, and the systematic review of the mathematical modeling of infectious disease like coronaviruses.

  • Essential Human Virology

    • 2nd Edition
    • Jennifer Louten
    • English
    *Textbook and Academic Authors Association (TAA) Textbook Excellence Award Winner, 2024*Essential Human Virology, Second Edition focuses on the structure and classification of viruses, virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses and emerging and dangerous viruses. Additionally, how viruses cause disease (pathogenesis) is highlighted, along with discussions on immune response to viruses, vaccines, anti-viral drugs, gene therapy, the beneficial uses of viruses, research laboratory assays and viral diagnosis assays.Fully revised and updated with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses, the book provides students with a solid foundation in virology.

  • Advanced Biosensors for Virus Detection

    Smart Diagnostics to Combat SARS-CoV-2
    • 1st Edition
    • Raju Khan + 3 more
    • English
    Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2. In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization.

  • Coronavirus Disease

    From Origin to Outbreak
    • 1st Edition
    • Adnan I. Qureshi + 2 more
    • English
    Coronavirus Disease: From Origin to Outbreak provides a comprehensive review of coronaviruses, particularly COVID-19, its transmission, and disease pathology. The book covers the viral structure and genetics of coronaviruses, the pathogenesis and unique characteristics of coronavirus infection, and the evolving nature of our understanding of coronaviruses and disease. It also looks at the history of SARS-CoV and MERS-CoV infections and its global spread. The book examines the effectiveness of various preventive measures and new therapeutic agents that are either currently available or expected to available. Finally, it details the psychological and societal impact the virus and disease has in outbreak regions and what the financial impact an outbreak has on the healthcare system and local economies.

  • Environmental and Health Management of Novel Coronavirus Disease (COVID-19)

    • 1st Edition
    • Mohammad Hadi Dehghani + 2 more
    • English
    Environmental and Health Management of Novel Coronavirus Disease (COVID-19) examines mitigation measures that can be adopted at the time of a novel coronavirus outbreak to lessen environmental contamination and impacts on human health. The book discusses origin, structure and pathogenesis, epidemiology, environmental transmission and the potential spread routes of COVID-19 via surfaces, air, water, wastewater, medical waste and food products. It also covers guidelines and protocols for setting safety conditions to provide adequate health care and reduce the risk of infection in health and non-healthcare settings, along with preventative measures and disinfection technologies. In addition, the book discusses challenges, opportunities and future perspectives, the global crisis, and global consequences on the environment and health. With contributions from experts, this book presents a multidisciplinary reference resource for virologists, microbiologists, public health professionals, environmental health managers and others engaged in the study and mitigation of the environmental and health impacts of the virus.

  • Inoculating Cities

    Case Studies of Urban Pandemic Preparedness
    • 1st Edition
    • Rebecca Katz + 1 more
    • English
    Inoculating Cities: Case Studies of Urban Pandemic Preparedness begins with a brief historical description of infectious disease outbreaks in cities as well as an overview of infectious disease outbreaks since 2000 that hold profound implications for cities and urban environments – such as severe acute respiratory syndrome (SARS) in 2003, H1N1 influenza in 2009, Ebola virus in 2014, Zika virus in 2015, and more recently, COVID-19 in 2020. Each of these outbreaks affected different geographies of the world and underscored the importance of urban pandemic preparedness or urban health security as a means of mitigating the threats posed by infectious diseases. This book describes several of the characteristics of cities that make them uniquely vulnerable to infectious disease threats which include, but are not limited to, their population density, population diversity, internal and external population movements, and inequalities in cities. Finally, the book discusses frameworks and capacities that are essential for preparing cities to prevent, detect, and respond to infectious disease outbreaks. With contributions from experts and researchers with first-hand experiences with infectious disease outbreaks, their impact on the management of disease, and pandemic preparedness in progressively urban societies, Inoculating Cities addresses the unique threats infectious diseases pose to urban environments and surveys innovative models that cities are using to combat these threats.

  • Encyclopedia of Virology

    • 4th Edition
    • Dennis H. Bamford + 1 more
    • English
    Encyclopedia of Virology, Fourth Edition, Five Volume Set builds on the solid foundation laid by the previous editions, expanding its reach with new and timely topics. In five volumes, the work provides comprehensive coverage of the whole virosphere, making this a unique resource. Content explores viruses present in the environment and the pathogenic viruses of humans, animals, plants and microorganisms. Key areas and concepts concerning virus classification, structure, epidemiology, pathogenesis, diagnosis, treatment and prevention are discussed, guiding the reader through chapters that are presented at an accessible level, and include further readings for those needing more specific information. More than ever now, with the Covid19 pandemic, we are seeing the huge impact viruses have on our life and society. This encyclopedia is a must-have resource for scientists and practitioners, and a great source of information for the wider public.

  • Plant Virus-Host Interaction

    Molecular Approaches and Viral Evolution
    • 2nd Edition
    • R.K. Gaur + 3 more
    • English
    Plant Virus-Host Interaction: Molecular Approaches and Viral Evolution, Second Edition, provides comprehensive coverage of molecular approaches for virus-host interaction. The book contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, synergism with pivotal coverage of RNA silencing, and the counter-defensive strategies used by viruses to overcome the silencing response in plants. This new edition introduces new, emerging proteins involved in host-virus interactions and provides in-depth coverage of plant virus genes’ interactions with host, localization and expression. With contributions from leading experts, this is a comprehensive reference for plant virologists, molecular biologists and others interested in characterization of plant viruses and disease management.

  • Innovation in Clinical Trial Methodologies

    Lessons Learned during the Corona Pandemic
    • 1st Edition
    • Peter Schueler
    • English
    Innovation in Clinical Trial Methodologies: Lessons Learned during the Corona Pandemic presents a selection of updated chapters from Re-Engineering Clinical Trials that feature innovative options and methods in clinical trials. The Coronavirus pandemic is an accelerator for digitalization in many industries, including clinical trials. This book considers best practices, alternative study concepts requiring fewer patients, studies with less patient interaction, the design of "virtualized" protocols, and moving from data to decisions. This book will be helpful to pharmacologists, physicians and clinical researchers involved in the process of clinical development and clinical trial design.

  • COVID-19

    The Essentials of Prevention and Treatment
    • 1st Edition
    • Jie-Ming Qu + 2 more
    • English
    COVID-19: The Essentials of Prevention and Treatment elaborates on the ethology, pathogenesis, epidemiology, clinical characteristics, treatment principles, rehabilitation and prevention, and prevention and control measures for COVID-19. Aimed at healthcare workers, and written to be a practical guide, six chapters cover the following aspects of COVID-19: respiratory viruses; pathogenesis; case definitions and diagnosis; treatment; prevention and disease control; and prospects for the management and research of respiratory virus infections. This book gives first-hand information on the prevention, control, diagnosis and treatment of COVID-19.COVID-19 was recognized as a pandemic in March 2020 by the World Health Organization. It is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians working in China, particularly where the outbreak was first identified in Wuhan, have built up knowledge of prevention and control measures, and diagnosis and treatment of this disease. These insights are now globally relevant. The authors of this book are senior physicians specializing in respiratory diseases, pulmonary diseases and critical care medicine, and are all clinical and scientific research experts working in China, with particular experience in Wuhan.

  • Applied Plant Virology

    Advances, Detection, and Antiviral Strategies
    • 1st Edition
    • L. P. Awasthi
    • English
    Applied Plant Virology: Advances, Detection, and Antiviral Strategies provides an overview on recent developments and applications in the field of plant virology. The book begins with an introduction to important advances in plant virology, but then covers topics including techniques for assay detection and the diagnosis of plant viruses, the purification, isolation and characterization of plant viruses, the architecture of plant viruses, the replication of plant viruses, the physiology of virus-infected hosts, vectors of plant viruses, and the nomenclature and classification of plants. The book also discusses defense strategies by utilizing antiviral agents and management strategies of virus and viroid diseases. With contributions from an international collection of experts, this book presents a practical resource for plant virologists, plant pathologists, horticulturalists, agronomists, biotechnologists, academics and researchers interested in up-to-date technologies and information that advance the field of plant virology.

  • Rabies

    Scientific Basis of the Disease and Its Management
    • 4th Edition
    • Anthony R. Fooks + 1 more
    • English
    Rabies: Basis of the Disease and Its Management, Fourth Edition is an authoritative reference on the current status of rabies, including the virological, clinical, and public health aspects and management recommendations. Rabies remains one of the most important global public health problems worldwide. Although many important developments have been made over the past century to combat this disease, rabies has become a re-emergent infection in the resource-constrained countries. The Fourth Edition updates this classic reference with comprehensive coverage of the molecular virology, pathogenesis, immunology, vaccines, public health aspects, and epidemiology of rabies and is completely revised, with new chapters that will cover historical developments in rabies intervention strategies, the evolution of rabies virus, modeling rabies control, and on the strategy for rabies elimination. Rabies, Fourth Edition, provides physicians, veterinarians, public health advisors, epidemiologists, and research scientists with a single source for authoritative and up-to-date information on the diagnosis, treatment, control, and prevention of this fatal infectious virus.

  • Human Papillomavirus

    Proving and Using a Viral Cause for Cancer
    • 1st Edition
    • David Jenkins + 1 more
    • English
    Human Papillomavirus: Proving and Using a Viral Cause for Cancer presents a steady and massive accumulation of evidence about the role of HPV and prevention of HPV-induced cancer, along with the role and personal commitment of many scientists of different backgrounds in establishing global relevance. This exercise involved years of personal commitment to proving or disproving an idea that aroused initial skepticism, and that still has difficult implications for some. It remains one of the big successes of medicine that exploited both established medical science dating back to the nineteenth century and new molecular genetic science during a time of transition in medicine.

  • Dengue Virus Disease

    From Origin to Outbreak
    • 1st Edition
    • Adnan I. Qureshi + 1 more
    • English
    Dengue Virus Disease: From Origin to Outbreak provides a detailed accounting of one of the world's fastest growing infections. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. This estimate puts nearly half the world’s population at risk. This book reviews the history, clinical and diagnostic aspects of dengue virus, also presenting our current knowledge on the pathophysiology of severe dengue and addressing the importance of dengue virus infections in those traveling to parts of the world where it is endemic.

  • Virus as Populations

    Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
    • 2nd Edition
    • Esteban Domingo
    • English
    Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere.

  • Emerging and Reemerging Viral Pathogens

    Volume 2: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens
    • 1st Edition
    • Moulay Mustapha Ennaji
    • English
    Emerging and Reemerging Viral Pathogens: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens, Volume Two presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control.

  • Emerging and Reemerging Viral Pathogens

    Volume 1: Fundamental and Basic Virology Aspects of Human, Animal and Plant Pathogens
    • 1st Edition
    • Moulay Mustapha Ennaji
    • English
    Emerging and Reemerging Viral Pathogens: Fundamental and Basic Virology Aspects of Human, Animal and Plant Pathogens, Volume One presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control.

  • Protein Modificomics

    From Modifications to Clinical Perspectives
    • 1st Edition
    • Tanveer Ali Dar + 1 more
    • English
    Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer’s, Huntington’s, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes.

  • Viral Polymerases

    Structures, Functions and Roles as Antiviral Drug Targets
    • 1st Edition
    • Satya Prakash Gupta
    • English
    Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent favorable targets for the design and development of antiviral drugs.

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