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Features, Transmission, Detection, and Case Studies in COVID-19
1st Edition - June 1, 2024
Editors: Rajkumar Rajendram, Victor R Preedy, Vinood Patel
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 6 4 6 - 8
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 6 4 7 - 5
Neurological Problems in COVID-19 examines the effects of the virus on the brain, as well as its transmission and clinical profile. Beginning with an introduction to the virus and… Read more
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Neurological Problems in COVID-19 examines the effects of the virus on the brain, as well as its transmission and clinical profile. Beginning with an introduction to the virus and its pathogenesis, transmission, and avoidance, sections on neurological symptoms and biomarkers in the brain uniquely describe the effects of this virus on this system. Vaccines and treatment are also discussed. Neurological issues covered include brain hypoxia, Parkinson’s disease, and incidence of COVID-19-related acute ischemic stroke. This volume is relevant for all neurologists and clinicians working to ensure the best outcomes and patient care of patients with COVID-19.
- Describes neurological issues caused by COVID-19, including stroke and loss of taste and smell
- Discusses COVID-19 biology, including pathogenesis, and transmission
- Outlines biomarkers in the brain associated with severity and disease outcomes
- Features individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of neurological symptoms
Neuroscientists, neurologists, clinicians, health scientists, public health workers, doctors, and research scientists.
Section 1: COVID-19: Introductory chapters
SARS-CoV-2 structure and replication
Focused features of the COVID-2019 coronavirus and non structural proteins nsp2 and nsp3 in its pathogenesis
The burden of COVID-19 pandemic: DALYs and beyond
Nursing Homes and COVID-19 Cases
Gender differences and COVID-19: A new narrative
Clinical profiles of COVID-19 patients
The COVID-19 patients in ICU
COVID-19 in the homeless
Section 2: Transmission and avoidance
Authors should begin their chapters by describing the different routes of transmission and steps to minimise this, then focus on the areas covered in their chapter title.
Pregnancy and vertical transmission of COVID-19
Droplets and aerosols and COVID-19
Nosocomial transmission of COVID-19
Geographical "hot zones" for otolaryngological exposure and COVID-19
COVID-2019 coronavirus and transmission during surgery
COVID-2019 coronavirus and superspreaders: lessons from veterinary research
COVID-19 virus transmission and surfaces
Physical distancing and beyond for COVID-19: a new narrative
COVID-19 coronavirus in the environment: wastewater and beyond
Section 3: Neurological Symptoms
Neurological features of COVID-19: a new narrative
Laboratory markers for predicting death from COVID-19
Brain hypoxia in COVID-19
COVID-19 and Parkinson’s disease
The Olfactory System – loss of taste and smell in COVID-19
Acute Ischemic Stroke and COVID 19
Section 4: Treatments and vaccines
Vaccines for the COVID-19 coronavirus
Techniques for development of COVID-19 coronavirus vaccines
Drugs active against COVID-19
Dexamethasone usage for COVID-19
Cytokine storms and use of tocilizumab in COVID-19
Section 5: Biomarkers in the Brain
Detection of SARS-CoV-2 RNA: the SimplexaTM COVID-19 direct assay
Biomarkers of COVID-19 severity
CSF inflammatory biomarkers in COVID-19
microRNAs as COVID-19 biomarkers in the brain
- No. of pages: 600
- Language: English
- Published: June 1, 2024
- Imprint: Academic Press
- Hardback ISBN: 9780323956468
- eBook ISBN: 9780323956475
RR
Rajkumar Rajendram
Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.
Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.
Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.
Affiliations and expertise
Consultant in Internal Medicine, King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi ArabiaVP
Victor R Preedy
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK Visiting Professor, University of Hull, UKVP
Vinood Patel
Vinood B. Patel, BSc, PhD, FRSC, is currently Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of liver disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress in neurological disorders and iron dysregulation in diabetes. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to the use or investigation of active agents or components. These books include The Handbook of Nutrition, Diet, and Epigenetics, Branched Chain Amino Acids in Clinical Nutrition, Cancer: Oxidative Stress and Dietary Antioxidants, Toxicology: Oxidative Stress and Dietary Antioxidants, Molecular Nutrition: Vitamins, The Neuroscience of Pain, Cognitive Behavioural Therapy. He is Editor of the ten-volume series Biomarkers in Disease: Methods, Discoveries and Applications
Affiliations and expertise
Professor, University Westminster, UK