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Elsevier

Books in Life sciences

  • Handbook of Computational Intelligence in Biomedical Engineering and Healthcare

    • 1st Edition
    • Janmenjoy Nayak + 3 more
    • English
    Handbook of Computational Intelligence in Biomedical Engineering and Healthcare helps readers analyze and conduct advanced research in specialty healthcare applications surrounding oncology, genomics and genetic data, ontologies construction, bio-memetic systems, biomedical electronics, protein structure prediction, and biomedical data analysis. The book provides the reader with a comprehensive guide to advanced computational intelligence, spanning deep learning, fuzzy logic, connectionist systems, evolutionary computation, cellular automata, self-organizing systems, soft computing, and hybrid intelligent systems in biomedical and healthcare applications. Sections focus on important biomedical engineering applications, including biosensors, enzyme immobilization techniques, immuno-assays, and nanomaterials for biosensors and other biomedical techniques. Other sections cover gene-based solutions and applications through computational intelligence techniques and the impact of nonlinear/unstructur... data on experimental analysis.

  • Metal and Nutrient Transporters in Abiotic Stress

    • 1st Edition
    • Aryadeep Roychoudhury + 2 more
    • English
    Metal and Nutrient Transporters in Abiotic Stress focuses on the different forms of environmental stress related to heavy metal, metalloid and nutrient deficiency that have the potential to inflict major damages to crop plants, leading to a massive decrease in crop yield and productivity. The book presents the current state of knowledge of the biochemical and molecular regulation of several classes of membrane transporters related to the uptake of metals/metalloids and nutrient elements during different stresses and their probable mechanisms of operation in plant stress tolerance. Metal and Nutrient Transporters in Abiotic Stress provides a comprehensive discussion that will help in mitigating multiple forms of stresses utilizing transporter proteins. Edited by leading experts and written by a global team of knowledgeable contributors, this book will further stimulate research in the field of transporter proteins and will foster further interests for researchers, academicians and scientists worldwide. It is complimented by its companion book titled Transporters and Plant Osmotic Stress.

  • Fibroblast Growth Factor 23

    • 1st Edition
    • Christian Faul + 2 more
    • English
    Fibroblast Growth Factor 23 describes how FGF23 was initially identified as a bone-derived factor targeting the kidney. As such, sections in this comprehensive book cover exciting research that shows that different FGF23 effects require distinct signaling receptors and mediators that differ among target tissues, cover FGF23 initially identified as a bone-derived factor targeting the kidney, look at FGF23 as a regulator of phosphate metabolism and beyond, and cover research on novel concepts of FGF receptor signaling. Additional sections cover biochemistry, pharmacology and nephrology, making this book an ideal reference source on FGF23.

  • Neurology of Vision and Visual Disorders

    • 1st Edition
    • Volume 178
    • English
    Neurology of Vision and Visual Disorders, Volume 178 in the Handbooks of Neurology series provides comprehensive summaries of recent research on the brain and nervous system. This volume reviews alterations in vision that stem from the retina to the cortex. Coverage includes content on vision and driving derived from the large amount of time devoted in clinics to determining who is safe to drive, along with research on the interplay between visual loss, attention and strategic compensations that may determine driving suitability. The title concludes with vision therapies and the evidence behind these approaches. Each chapter is co-written by a basic scientist collaborating with a clinician to provide a solid underpinning of the mechanisms behind the clinical syndromes.

  • Pancreatic B Cell Biology in Health and Disease

    • 1st Edition
    • Volume 359
    • English
    Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more. Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease.

  • The Complex Interplay Between Gut-Brain, Gut-Liver, and Liver-Brain Axes

    • 1st Edition
    • Cristina Stasi
    • English
    The Complex Interplay Between Gut–Brain, Gut–Liver, and Liver–Brain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gut–brain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurolog... disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gut–liver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liver–brain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome.

  • Tumor Microenvironment Regulation of Tumor Expansion

    • 1st Edition
    • Domenico Ribatti
    • English
    Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions. Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs is a key factor in improving treatment outcome, especially in new therapeutic treatments targeting components of the tumor microenvironment. This book is a valuable resource for cancer researchers, clinicians, graduate students, and scientists in many biomedical fields who are interested in the complex relationship between the tumor microenvironment and its context in specific organs.

  • Cellular Networks in Development

    • 1st Edition
    • Volume 143
    • English
    Current Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sections on Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Left-right asymmetry research in Xenopus: Questions solved and new frontiers, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis of Xenopus genomes, Transcriptional regulation during zygotic genome activation, and much more.

  • Reciprocal Translation Between Pathophysiology and Practice in Health and Disease

    • 1st Edition
    • Peter B. Soeters + 1 more
    • English
    Reciprocal Translation Between Pathophysiology and Practice in Health and Disease brings a novel perspective, closing the knowledge gap between normal/abnormal physiology. Chapters describe the basic mechanisms underlying a disease or trauma-related response, describe consequences in practice, and provide insights on how to use information to better understand disease outcomes. Other sections explore how these responses are beneficial and driven by similar hormones and inflammatory immune cell derived modulators. This is a must-have resource for those seeking an authoritative and comprehensive understanding on how to treat the basic mechanisms underlying disease or trauma-related responses.With contributions from Petronella L.M. Reijven.

  • Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations Part 2

    • 1st Edition
    • Volume 33
    • English
    Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations, Part Two, Volume 33 in the Advances in Biomembranes and Lipid Self-Assembly series, highlights new advances in the field, with sections in this new release covering Biomembranes of extracellular vesicles: The protein component, Protocol for isolation of Microvesicles form blood plasma, Urinary Extracellular vesicles at single patient level for clinical research, Treatment of chronic wounds with platelet and extracellular vesicles enriched plasma, Liposome loading and imaging, The Potential of Extracellular Vesicles for Brain Repair, Nucleic acids cargo of extracellular vesicles: Analysis and physiological function, Propolis flavonoids and terpenes, and much more.

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