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Books in Life sciences

MRI Atlas of the Infant Rat Brain
Brain Segmentation
1st Edition
August 21, 2022
Dusica Bajic + 2 more
English
MRI Atlas of the Infant Rat Brain: Brain Segmentation features an entirely new coronal, sagittal and horizontal set of tissue cut in regular 9 µm intervals with accompanying photographs of MRI data and color drawings of selected brain regions in the three planes. The use of the single brain allows for greater consistency between sections, while color masking offers advances in manual segmentation techniques with increased refinement in the definition of brain areas. Readers will benefit from uniform and consistent manual tissue segmentation of MRI data in an infant rat brain. This volume provides readers the first infant rat brain MRI atlas and a valuable resource in research analyses of the developing brain for structural and functional MRI analyses.
Genetics and Neurobiology of Down Syndrome
1st Edition
August 21, 2022
Bani Bandana Ganguly
English
Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development.
Handbook of Neuro-Oncology Neuroimaging
3rd Edition
August 21, 2022
Herbert B. Newton
English
With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology.
PDE Modeling of Tissue Engineering and Regenerative Medicine
Computer Analysis in R
1st Edition
August 20, 2022
William E. Schiesser
English
PDE Modeling of Tissue Engineering and Regenerative Medicine: Computer Analysis in R presents the formulation and computer implementation of mathematical models for the forefront research areas of tissue engineering and regenerative medicine. The mathematical model discussed in this book consists of a system of eight partial differential equations (PDEs) with dependent variables. The computer-based example models are presented through routines coded in R—a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Includes detailed examples that the reader can execute on modest computers.
Autophagy Dysfunction in Alzheimer's Disease and Dementia
1st Edition
August 20, 2022
Tadanori Hamano + 1 more
English
Autophagy Dysfunction in Alzheimer’s Disease and Dementia provides an overview for researchers and clinicians on the mechanisms involved in protein degradation in Alzheimer’s. The book discusses the implication of autophagy dysfunction in these diseases and how it causes degenerated proteins, including aggregated tau and aggregated amyloid protein. Other sections explores the possibilities of potential drug development through autophagy modulation, making this a great resource on the study of how autophagy dysfunction has been linked to the accumulation of misfolded proteins that cause death of neurons in Alzheimer’s and other neurodegenerative diseases.
Phytoconstituents and Antifungals
1st Edition
August 20, 2022
Awanish Kumar
English
Phytoconstituents and Antifungals covers a wide range of specific information on various phytoconstituents, their antifungal mode and the diagnosis and management of fungal infections. The book offers encouragement and empowers readers to re-embrace their knowledge of phytoconstituents and their various antifungal activities against most opportunistic pathogenic fungi as fungal diseases cause an estimated 1.5+ million deaths annually and over one billion people suffer from severe fungal disease. In this complex scenario, it is now clear that global warming and accompanying climate changes have resulted in increased incidence of many fungal infections. On the basis of all these factors, concerns on the occurrence of a pandemic fungal origin in the near future have been raised. In this context, to stop forgetting and underestimating fungal diseases is mandatory.
System Vaccinology
The History, the Translational Challenges and the Future
1st Edition
August 20, 2022
Vijay Kumar Prajapati
English
Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.
The Chromosome 22q11.2 Deletion Syndrome
A Multidisciplinary Approach to Diagnosis and Treatment
1st Edition
August 19, 2022
Donna M. McDonald-McGinn
English
The Chromosome 22q11.2 Deletion Syndrome: A Multidisciplinary Approach to Diagnosis and Treatment serves as the first comprehensive, user-friendly resource on the etiology, prognosis, and recurrence risk associated with the chromosome 22q11.2 deletion syndrome. Leading international contributors cover the background, genetics, testing methods, and pathophysiology of 22q11.2DS, placing emphasis on a strong foundation for multidisciplinary treatment strategies. Written by specialists in every applicable subspecialty, such as, cardiology, immunology, endocrinology, gastroenterology, hematology, ophthalmology, neurology, and psychiatry, among other fields. This book presents an authoritative resource with full color images that enhance concept illustration and aid in real-time decision-making. As 22q11.2 deletion syndrome has become a model for understanding rare and frequent anomalies, numerous medical issues, cognitive and behavioral phenotypes, and later onset conditions, this text will become the go to resource for clinicians, researchers, trainees, and motivated family members, in gaining a full understanding of this complex chromosomal disorder.
Oral Delivery of Therapeutic Peptides and Proteins
1st Edition
August 18, 2022
Puneet Tyagi + 1 more
English
Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.
Sex and Gender Differences in Neurological Disease
1st Edition
Volume 164
August 18, 2022
English
International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

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