
Cerebrospinal Fluid and Subarachnoid Space
Volume 1: Clinical Anatomy and Physiology
- 1st Edition - October 8, 2022
- Imprint: Academic Press
- Editors: R. Shane Tubbs, Joe Iwanaga, Elias B. Rizk, Anthony V. D'Antoni, Aaron S. Dumont
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 9 5 0 9 - 3
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 9 5 1 0 - 9
Cerebrospinal Fluid and Subarachnoid Space: Volume 1: Clinical Anatomy and Physiology is the first book devoted to the comprehensive clinical anatomy of the cerebrospinal fluid f… Read more

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Request a sales quoteCerebrospinal Fluid and Subarachnoid Space: Volume 1: Clinical Anatomy and Physiology is the first book devoted to the comprehensive clinical anatomy of the cerebrospinal fluid for neurosurgeons, neurologists, and neuroscientists. Knowledge of the cerebrospinal fluid (CSF) and the subarachnoid space is necessary for almost all fields of medicine. The book covers a wide swath of topics related to CSF with a focus on topics relevant to neuroscience specialists including researchers, neurologists, neurosurgeons, and neuroradiologists. Topics span from neuroanatomy, neurophysiology, CSF in different disease states and more. Various fresh and fixed cadaveric photographs helps readers obtain a better understanding of anatomy and complications related to CSF.
- First comprehensive book devoted to clinical anatomy of cerebrospinal fluid and subarachnoid space
- Edited by neuro-anatomists and neurosurgeons, giving it a multimodal perspective
- Nerves and vessels color-coded to differentiate from other tissues
Practitioners and researchers in neurology, neurosurgery and neuroanatomy Spine surgeons, anatomists, medical students, resident, fellows, nurses
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter 1. Cerebrospinal fluid physiology
- Introduction
- CSF secretion
- CSF circulation
- Cerebrospinal fluid absorption
- Conclusions
- Chapter 2. Development of the ventricles, choroid plexus and CSF outflow system: comparative perspective
- Introduction
- The brain ventricular system (BVS)
- Neuroanatomy of the brain ventricular system in zebrafish
- Development of the choroid plexus (CP)
- Development of the CP vasculature
- Development of the CP stroma
- The CSF outflow system
- Chapter 3. The cerebral ventricles
- Lateral ventricles
- Foramen of Monro
- Third ventricle
- Aqueduct of Sylvius
- Fourth ventricle
- Foramen of Magendie
- Foramen of Luschka
- Chapter 4. Franciscus Sylvius (1614–72) and his aqueduct
- Anatomy of the aqueduct of Sylvius
- Chapter 5. The foramen of Monro
- Introduction
- History
- Embryology
- Microsurgical anatomy of the foramen of Monro
- Superficial landmarks for the foramen of Monro
- Pathology
- Treatment
- Conclusions
- Chapter 6. The anatomy and history of the foramina of Luschka
- Introduction
- Chapter 7. François Magendie (1783–1855) and his foramen
- Chapter 8. The subarachnoid space
- Introduction
- The carotid-chiasmatic walls
- Double membranes (types A, B)
- Triple membranes
- Subarachnoid space within the fallopian canal
- Chapter 9. The basal subarachnoid cisterns
- Introduction
- Discussion (surgical anatomy approaches, treatment)
- Chapter 10. Anatomy of the arachnoid granulations
- Introduction
- Histology
- Function
- Variations of the arachnoid granulations
- Location
- Other
- Chapter 11. Ectopic arachnoid granulations
- Introduction
- Chapter 12. The choroid plexus
- Introduction
- Anatomy
- Function of the choroid plexus
- Conclusion
- Chapter 13. Choroid plexus of the fourth ventricle
- Introduction
- Conclusions
- Chapter 14. The choroidal fissure and choroidal fissure cysts
- Introduction
- Conclusions
- Chapter 15. Subarachnoid trabeculae
- Overview
- Morphology and structure
- Size and distribution
- Material and properties
- Structural mechanics
- Solid-fluid interaction
- Role of trabeculae in the SAS
- Summary
- Chapter 16. The blood brain barrier
- Introduction
- Development of the blood brain barrier
- Anatomy of the BBB
- Normal physiology of the blood brain barrier
- Blood brain barrier in pathological conditions
- Conclusion
- Chapter 17. The glymphatic system
- Introduction
- Discussion
- Conclusions
- Chapter 18. Transport of ions across the choroid plexus epithelium
- Barrier-function of the choroid plexus
- Transcellular solute transport
- The Na+-K+-ATPase
- The Na+/H+ exchangers, NHE
- The Na+-channels, ENaC
- The Na+-K+-2Cl− cotransporter 1, NKCC1
- The K+-Cl− cotransporters
- The K+ channels
- The Cl− channels
- The Na+-dependent HCO3− transporters, NBCe2, NCBE, and NBCn1
- The anion exchanger 2, AE2
- Carbonic anhydrase
- Transcellular water transport of the CPE
- Paracellular transport of water and solutes
- Net acid/base transport by the choroid plexus
- Divalent cations
- Future perspectives
- Chapter 19. Imaging of the subarachnoid space and cerebrospinal fluid
- Introduction
- CSF flow imaging
- CSF imaging artifacts
- Percutaneous needle access of the SAS
- Imaging of SAS and CSF pathology
- Blood in the SAS
- Cerebrospinal fluid leaks
- CSF infections
- Leptomeningeal carcinomatosis
- Chapter 20. Biomarkers in the cerebrospinal fluid during pregnancy: focus on beta-amyloid and tau in preeclampsia and HELLP syndrome
- Biomarkers in the cerebrospinal fluid
- CSF biomarkers in the maternal brain
- CSF biomarkers in PE and HELLP syndrome
- Summary and outlook
- Index
- Edition: 1
- Published: October 8, 2022
- Imprint: Academic Press
- No. of pages: 340
- Language: English
- Hardback ISBN: 9780128195093
- eBook ISBN: 9780128195109
RT
R. Shane Tubbs
R. Shane Tubbs, MS, PA-C, PhD is a native of Birmingham, Alabama, USA and a is a clinical anatomist, author, editor, educator, and researcher. He is Professor of Neurosurgery, Neurology, Surgery, and Structural & Cellular Biology, Director of Surgical Anatomy at Tulane School of Medicine and Program Director of Anatomical Research in the Clinical Neuroscience Research Center at Tulane University School of Medicine, New Orleans, Louisiana and Department of Neurosurgery and Ochsner Neuroscience Institute Ochsner Health System, New Orleans, LA. He has multiple honorary professorships/faculty positions both in the US and abroad. Dr. Tubbs is President-elect of the American Association of Clinical Anatomists (AACA) and serves as its Journal’s (Clinical Anatomy) Editor-in-Chief. Dr. Tubbs’ research interests are centered around what has been termed “reverse translational anatomy research” where clinical/surgical problems are identified and solved/explained with anatomical studies. This investigative paradigm in anatomy has resulted in over 1,800 peer reviewed publications from his laboratory. Dr. Tubbs’ laboratory has made novel discoveries in human anatomy and in 2018, he was listed as a “hyperprolific author” in the journal Nature. Dr. Tubbs sits on the editorial board of over 10 anatomical journals and over 30 clinical journals and has reviewed for over 150 various scientific journals. He has authored/edited over 50 books and over 80 book chapters primarily in anatomical and neurosurgical textbooks. Lastly, Dr. Tubbs is Chair of the Federative International Programme on Anatomical Terminologies (FIPAT) and oversees six working groups dedicated to this topic. Under his leadership, the second edition of Terminologia Anatomica was just published.
Affiliations and expertise
Professor, Director of Surgical Anatomy, Tulane University School of Medicine, Program Director of Anatomical Research, Clinical Neuroscience Research Center, Department of Neurosurgery, Department of Neurology, Tulane University School of Medicine, Department of Structural and Cellular Biology, Department of Surgery, Tulane University School of Medicine, USAJI
Joe Iwanaga
Joe Iwanaga, DDS, PhD, is a clinical anatomist and an oral and maxillofacial surgeon. He is the author of more than 400 articles in peer-reviewed journals. Dr. Iwanaga is a Councilor-at-Large of the American Association of Clinical Anatomists, and Coordinator of the FIPAT Oral Anatomy Working Group of the International Federation of Associations of Anatomists. He is a Dental, Oral and Maxillofacial Section editor of the journal Clinical Anatomy.
Affiliations and expertise
Associate Professor of Neurosurgery and Neurology at Tulane University School of Medicine, New Orleans, Louisiana, USA.
Associate Professor of Anatomy and Dental and Oral Medical Center at Kurume University School of Medicine, Kurume, Fukuoka, Japan.ER
Elias B. Rizk
Dr. Rizk is a neurosurgeon at the Penn State Hershey Medical Center with a clinical specialty in pediatric peripheral nerve surgery. He has multiple publications on the PNS and is active in basic science research regarding peripheral nerve regeneration.
Affiliations and expertise
Neurosurgeon, Pennsylvania State University, Hershey, PA, USAAD
Anthony V. D'Antoni
Anthony V. D'Antoni works in the Department of Radiology at Weill Cornell Medicine, New York, NY, USA.
Affiliations and expertise
Department of Radiology, Weill Cornell Medicine, New York, NY, USAAD
Aaron S. Dumont
Aaron S. Dumont works at Tulane University in New Orleans, Louisiana, USA.
Affiliations and expertise
Tulane University, New Orleans, Louisiana, USARead Cerebrospinal Fluid and Subarachnoid Space on ScienceDirect