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Elsevier

Books in Life sciences

  • Climate Change and Agricultural Ecosystems

    Current Challenges and Adaptation
    • 2nd Edition
    • Olubukola Oluranti Babalola + 3 more
    • English
    Fully revised to include the latest scientific developments, Climate Change and Agricultural Ecosystems: Current Challenges and Adaptation, Second Edition continues to provide vital insights into the complex and dynamic relationship between climate, agriculture, soil and plants. Building on its proven value in guiding real-world application as well as inspiring further research, this new edition includes new insights and practices. Agricultural ecosystems are highly dependent on weather and climate for the production of necessary foods to sustain human life. Despite leading cutting-edge tools and technologies for developing improved varieties, genetically modified organisms, and irrigation systems, climate change is still a major constraint to agricultural productivity. It takes years to assess the impacts of climate change and vulnerability to it and to prepare proper countermeasures against it. Developing countermeasures drawn based on scientific diagnosis and assessment of the impacts of climate change on agriculture are essential in establishing the vision and administrative policies of future agriculture. Climate Change and Agricultural Ecosystems focuses on recent research and updates on interactions between agriculture, ecosystems, environment, and climate change bringing together ideas and innovations of the latest scientific findings on climate change and enriched by renowned researchers knowledge and experience in this field. It reflects the importance of acting now on climate change: to eliminate hunger; to enable the agriculture sectors to adapt to climate change.

  • Parasitic Protozoa Membranes

    Structure, Singularities and Host-Pathogen Interaction
    • 1st Edition
    • Volume 95
    • English
    Parasitic Protozoa Membranes: Structure, Singularities and Host-Pathogen Interaction, Volume 95 in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Hormesis, Brain Aging and Metabolism

    • 1st Edition
    • Volume 295
    • English
    Hormesis, Brain Aging and Metabolism, Volume 295 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Aging and brain metabolism, Calorie restriction: brain physiological and biological aspects, Intermittent fasting and ketone bodies, Physical exercise and brain health: running x sedentary lifestyle, Phytochemicals and brain health, Environmental enrichment and neuroplasticity, Hormesis and brain disease, Neuroinflammation and hormesis, and more.Additional chapters cover Glucocorticoids and Neuroinflammation and Hormesis and cancer.

  • Fruit Microbiome

    Emerging Aspects in Postharvest Disease Management
    • 1st Edition
    • Ajay Kumar + 2 more
    • English
    Fruit Microbiome: Emerging Aspects in Postharvest Disease Management covers all areas of microbial ecology and serves as a basis for innovative methods of microbiome engineering and the incorporation of probiotics on fruit nutritional quality. Emphasizing the latest advancements in the fruit microbiome and applications in biocontrol perspectives, the book includes advanced and recent insights into the development of microbial pesticides that will be helpful for those seeking ways to protect and improve plant health and yield protection.Phyto-mic... plays a crucial role in maintaining the health and productivity of all plants, including fruit plants whose yield contributes to global food security. Fruit also harbors numerous microbial communities as an epiphytes or endophytes, and theses microbes play a vital role in protecting them from pathogen invasion during pre-or- postharvest storage. Further, the development and commercialization of several biocontrol products derived from fruits microbiome have proven relevant in broader plant disease management.

  • Pharmacoepigenetics

    • 2nd Edition
    • Volume 10
    • Ramón Cacabelos
    • English
    Pharmacoepigenetics, Second Edition, Volume Ten in the Translational Epigenetics series, is a comprehensive reference on the role of epigenetics and epigenomics in drug discovery and development. Here, leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.This new edition has been fully revised to address recent advances in epigenetics, from new natural and synthetic compounds with epigenetic effects to the role of epigenetics in the pathogenesis of a growing number of complex diseases, including further cancers, cardiovascular disorders, and brain disorders. Newly identified molecular components in the functional architecture of the epigenetic machinery, as well as practical and relevant pharmacoepigenetics topics related to COVID-19 and other world health challenges are also discussed.

  • Therapies for Treatment-Resistant Depression

    Neuropharmacology and Neurostimulation
    • 1st Edition
    • James Murrough + 1 more
    • English
    Therapies for Treatment-Resistant Depression: Neuropharmacology and Neurostimulation provides readers with an authoritative, comprehensive and targeted treatment guide. The first section reviews the essential knowledge and methods of clinical neuroscience and neuropsychopharmacol... techniques as they apply to novel treatment discovery for depression. This is followed by detailed chapters on ketamine, esketamine, other glutamate modulators in development, GABA modulators, neuropeptides, anti-inflammatory agents, and other classes of novel therapeutics under study for TRD and related mood disorders.The last section consists of a set of chapters of special interest that includes current and future research directions, development of psilocybin-based interventions and other psychedelic compounds currently under study for TRD and advances in biomarker-guided and personalized treatment. Edited by world renowned experts in the field, this book is the ultimate resource for researchers and clinicians.

  • The Handbook of Dopamine

    • 1st Edition
    • Volume 32
    • Stephanie J. Cragg + 1 more
    • English
    The Handbook of Dopamine captures current understanding of dopamine biology in the brain, including anatomical organization of dopamine neurons, their molecular and genetic diversity, synaptic and circuit connectivity, receptor function and signalling, through to diverse roles in behaviors and finally, dysfunction in disease. This volume compiles a comprehensive set of perspectives from a large number of leading scientists working in dopamine research. The volume describes the current state-of-the-field, summarizing knowledge that has been transformed in the last decade through the advent and application of sophisticated new technologies.

  • Advanced Technologies for Coupled Enhancement of Gas-Solid Separation

    • 1st Edition
    • Chunxi Lu + 1 more
    • English
    Advanced Technologies for Coupled Enhancement of Gas-Solid Separation systematically explains the principles of cyclonic separation, the structural characteristics of equipment, the flow field in the separator, and new concepts and methods of coupled enhancement on cyclonic separation. The book provides basic theories and design methods as well as several new technologies and representative industrial application cases. This reference can be used by scholars, engineers, technicians, and students in the field of oil refining, petrochemical, coal chemical, and pan-chemical manufacturing.

  • Regenerative Hepatology and Liver Transplantation

    • 1st Edition
    • Volume 2
    • Paulo Martins + 1 more
    • English
    Regenerative Hepatology and Liver Transplantation is the second volume in the Regenerative and Transplant Medicine series. This volume is essential as no field in the biomedical sciences has more interest than organ transplantation regarding regenerative medicine, primarily because of the urgent need to improve transplant outcomes and increase transplantation rates is critical to treat the many patients suffering from liver disease.The goal of this book is to bridge regenerative hepatology and transplant medicine, by illustrating the state of the art of clinical liver transplantation, as well as of the progress of regenerative medicine (RM) investigations aiming at the bioengineering, regeneration, and repair of the liver.This volume is necessary and would be placed well in the current global trend toward increasing organ donation utilizing such cutting-edge technologies. Written by the world’s experts in the field of liver diseases, it is a perfect reference for transplant operators, researchers, regenerative medicine operators, tissue engineering operators, biotech operators, and those in academia, industry, and regulatory agencies working to advance the field.

  • Bleeding Disorders During Pregnancy

    Critical Care Obstetrics
    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Bleeding Disorders During Pregnancy is a volume in the Critical Care Obstetrics series. It is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women with various health compromises that include bleeding. The authors have gathered the best evidence-based material explicitly focused on severe complications in pregnant patients and postpartum. Among the chapters, the book covers medical–surgical complications that any patient can present, such as obstetrics, hemorrhage, hypovolemic shock, and other bleeding complications specific to pregnancy.

  • Role of Antioxidants in Abiotic Stress Management

    • 1st Edition
    • Zaid Ulhassan + 2 more
    • English
    Role of Antioxidants in Abiotic Stress Management covers the antioxidant defense system in plants, providing key insights on how to generate tolerant varieties that can adapt to harsh environmental conditions without adverse impacts on crop productivity. The book covers a broad range of antioxidant responses, describing how global climate changes and the overexploitation of natural or anthropogenic resources creates abiotic stressors. The potential impacts of factors such as heavy metals/metalloids, drought/water deficit, salinity, extreme temperatures, anoxia, and high light intensity are covered, along with discussions on how to improve crop growth and development at different stages.Written by a team of international experts, this book provides an important reference on morphological, physiological, biochemical, metabolic, anatomical and molecular responses of plants under stress factors.

  • Neural Interfaces

    • 1st Edition
    • Davide Valeriani + 1 more
    • English
    Neural Interfaces is a comprehensive book on the foundations, major breakthroughs, and most promising future developments of neural interfaces. The book contains the foundational topics of neural technologies, such as what is a brain signal and how to record them. It provides step-by-step tutorials on how to start with small projects and use machine learning to identify specific brain patterns. It also reviews recent advances that promise to guide future developments, including minimally invasive neural technologies. Through a mix of introductory and cutting-edge research, this book is a unique resource to those with an interest in neural interfaces and the latest technologies.

  • Reactive Oxygen Species in Cardiometabolic Syndrome, Neuronal Diseases and Cancer

    From Bench to its Potential Therapeutics
    • 1st Edition
    • Esma R. Isenović + 1 more
    • English
    Reactive Oxygen Species in Cardiometabolic Syndrome, Neuronal Diseases and Cancer: From Bench to its Potential Therapeutics systematically summarizes findings concerning the biochemical properties of various reactive oxygen species (ROS). The book opens with foundational coverage of ROS, ROS signaling, as well as the role of ROS in controlling gene expression. Subsequent chapters cover molecular mechanisms of ROS, regulation of gene expression, and antioxidant supplementation with cardiometabolic syndrome, various neuronal diseases, and cancer. It concludes with recent findings on therapeutic modulations of intracellular levels of ROS, which may significantly impact the development of novel agents for treating the conditions covered.This is a must-have reference for scientists and medical professionals seeking to enhance their knowledge of ROS research and the impact on treatments for cardiometabolic syndrome, neuronal diseases, and cancer.

  • IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care

    • 1st Edition
    • Tuan Anh Nguyen
    • English
    IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care explores the latest advances in nanotechnology, artificial intelligence, Internet of Medical Things (IoMT), digital twin, and wireless sensor networks for real-time cancer care, enabling efficient decision-making and treatment. The book examines how data from medical nanosensors can be integrated with the technology of digital twins for cancer forecasting and monitoring, providing accessible smart insights via remote and mobile devices. By combining the strengths of smart nanotechnology, IoT-based platforms, WSN technologies, and DT, a powerful medical system can be developed for smart cancer care.This system can help in early diagnosis, targeted drug delivery, real-time monitoring, and personalized treatment, ultimately improving patient outcomes.

  • Phytomicrobiome and Stress Regulation

    • 1st Edition
    • Azam Khan + 3 more
    • English
    Phytomicrobiome and Stress Regulation, a volume in the Microbiome Research in Plants and Soil series, provides an in-depth examination of how plant-associated microbial communities mitigate various stresses. The book explores the complexities of abiotic and biotic stresses faced by plants, emphasizing the importance of the phytobiome in stress alleviation. This comprehensive overview sheds light on the significant role that microbial composition and diversity play in driving ecological functions and enhancing plant resilience. In addition to addressing stress mitigation, the book highlights advances in applied crop microbiology and the dynamic responses of microbial communities to environmental changes.It underscores the impact of these communities on soil functioning and ecosystem health, making it a critical resource for understanding future climate change scenarios and their implications for plant health. Through detailed studies and evidence-based insights, the book aims to foster a more complete understanding of the intricate relationship between plants and their microbial allies.

  • Cardiac Sarcoidosis

    A Multi-discipline Approach
    • 1st Edition
    • Robert Phillip Baughman + 2 more
    • English
    In the past 5 years, there has been a tremendous increase in interest regarding diagnosis and management the cardiac involvement in sarcoidosis. This includes new imaging techniques, new evidence-based guidelines regarding diagnosis and treatment, as well as results of registries providing information regarding the outcome of disease. With this new information, the diagnosis and treatment of cardiac sarcoidosis has become better served. Many centres are now developing multi-disciplinary clinics and conferences to evaluate and treat these patients. These clinics highlight the problem that many different specialities are involved in the care of these patients. A book focusing on the different aspects of the disease will give a reference source for these efforts.Cardiac Sarcoidosis: A Multi-discipline Approach focuses on an important aspect of sarcoidosis: cardiac involvement. From pathology to diagnosis and screening of the disease through treatment options, the book comprehensively reviews known knowledge and explores emerging topics in the field, accompanied by illustrative cases and evidence-based recommendations in outlining the best disease management practices. The book is written by international experts in the field and serves as an essential reference for both clinicians and researchers on cardiac sarcoidosis.

  • Motion Control of Soft Robots

    • 1st Edition
    • Wenyu Liang + 3 more
    • English
    Motion Control of Soft Robots provides an overview of the general concepts and most recent technological updates in soft robot motion control. The book provides systematic coverage of theoretical and practical aspects in system modeling and motion control strategies, presenting novel ideas, methods, and future outlook related to motion control of soft actuators and robots, including model-based control, model-free control, and bioinspired control. This book is useful for researchers, engineers, and students of robotics who can expect to learn how to design and implement various techniques to obtain solutions to control problems in soft robot control and nonlinear system control.

  • Quantum Health AI

    The Revolution of Medicine, Public Health, and Global Health by Quantum Computing-Powered Artificial Intelligence
    • 1st Edition
    • Dominique J. Monlezun
    • English
    Quantum Health AI: The Revolution of Medicine, Public Health, and Global Health is the first comprehensive book defining the transformation of the global health ecosystem by the fusion of our most powerful technologies—quantum computing and artificial intelligence—while defending an actionable human-centred approach to doing so responsibly, equitably, and sustainably. We can continue to watch wars, diseases, poverty, polarization, cyber-crime, and climate change only worsen. Our strongest technologies can remain centralized in a small number of companies and countries for their profit and power. Or we can cooperatively put quantum AI to work for the health of all of us, by better managing this technology’s overarching strategic competition between democracies and autocracies, along with the public and private sectors (balancing human security with national security, economic growth with household livelihoods, individual rights with the common good). This book draws on the decade plus of original research and first-hand perspective of the world’s first triple doctorate-trained physician-data scientist and AI ethicist. It unpacks the history, science, values, and political economics framing and driving quantum AI (including its physics, metaphysics, ethics, governance, computing, sensing, communication, materials, and security), the global health ecosystem (healthcare systems, public health agencies, biotechnology companies, and development institutions), and their growing integration, wins, and challenges. This one-stop book provides a global, inclusive, and practical guide for understanding and shaping these societal and technological trends. It thus empowers health, technology, and policy students, practitioners, professionals, researchers, and leaders in organizations, universities, companies, and governments—ultimate... to make and maintain the human-centred quantum AI safeguarding and advancing humanity’s health, home, and future.

  • Advances in DNA and mRNA-Based strategies for Cancer Immunotherapy: Part B

    • 1st Edition
    • Volume 166
    • English
    Advances in Immunology, Volume 166, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Thyroid Cancer Update, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 54-3
    • Kenneth Burman + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Jacqueline Jonklaas and Kenneth Burman bring their considerable expertise to the topic of Thyroid Cancer Update. Top experts in the field cover novel treatments, screening strategies, and management, along with topics about survivorship and quality of life.

  • ​Theoretical and Clinical Geropharmacology​

    • 1st Edition
    • Volume 104
    • English
    ​Theoretical and Clinical Geropharmacology​, explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. Chapters in this new release include Senotherapeutics: Milestones, innovations, and future prospects, Game Changer: Navigating between challenges and hopes in Geropharmacology, Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disorders, Pharmacological frontiers in senescence: Transforming senescence with drug repurposing, Pharmacological potential of calorie restriction mimetics in mitigating brain aging, Isothiocyanates from cruciferous plants as geroprotectors, and much more.Other chapters cover Cellular parabiosis as a senotherapeutic approach, Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseases, Mitochondria-associa... membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stress, Cellular senescence and senotherapeutics in cardiovascular diseases, Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients, Geropharmacology and gastrointestinal surgery, Oxygen-ozone adjunct therapy in aging and senescence-related disorders, and more.

  • Sorghum and Millets

    Chemistry, Technology, and Nutritional Attributes
    • 3rd Edition
    • John Taylor + 2 more
    • English
    Sorghum and Millets: Chemistry, Technology, and Nutritional Attributes, Third Edition is the leading resource for state-of-art knowledge on grain science and utilization surrounding sorghum and millets. The book covers important scientific knowledge, including basic science—genetics, chemistry, and biochemistry—food chemistry, nutritional quality and health-promoting attributes, agronomy, and food and feed processing technologies. Other sections delve into structure, chemistry, biochemistry, grain components, and the technologies used for food processing. Additionally, it provides holistic and complete information about all technologies in the sorghum and millets food value chain, from genomics-based breeding to grain- and product quality assurance.Sorghum and the millets are the 5th and 6th most important cereal grains in terms of production and are cultivated across the world. They have a very wide range of end-uses as traditional staple foods and beverages, modern processed foods, and with respect to sorghum, industrial applications, including biofuels, and as an animal and aquaculture feedstuff.

  • Environmentally Safe Strategies for Plant Protection Against Biotic and Abiotic Stresses

    • 1st Edition
    • Parissa Taheri
    • English
    Environmentally Safe Strategies for Plant Protection Against Biotic and Abiotic Stresses presents environmentally friendly and safe methods for plant protection against not only biotic stresses caused by various pathogens and pests, but also against abiotic stresses such as salinity, drought, UV radiations, flood, unfavorable temperature, and pH, etc. The book aims to present approaches for both abiotic and biotic stresses, providing a valuable, integrated view to inspire new research as well as to implement and develop new practices.As global demand for organic food and feed products increases, it is necessary to focus on research areas related to discovery, application and demonstrating the modes of action of natural compounds obtained from various plants or mushrooms, as well as beneficial microbes and their metabolites involved in plant protection against biotic and abiotic stresses. These natural compounds, biocontrol agents and their volatile or non-volatile metabolites, which might have direct antagonism against phytopathogens and pests or indirect effect via induction of plant defense, could be formulated and used with high durability to control various environmental stresses in an eco-friendly manner.

  • Computational Biomechanics of Human Joints

    • 1st Edition
    • Abdelwahed Barkaoui + 2 more
    • English
    Computational Biomechanics of Human Joints delves into the intricate details of each joint, exploring anatomical, mechanical, pathological, and therapeutic aspects. The book offers a comprehensive understanding of joint biomechanics by dedicating each chapter to specific joints, detailing their anatomical structure, biomechanical mechanisms, associated diseases, and pathologies. It also covers treatments, surgical interventions, and imaging-based modeling alongside numerical simulation techniques using the finite element method. This approach provides readers with an innovative perspective on the technological advancements in joint biomechanics. In addition to exploring joint-specific details, the book discusses the advantages and limitations of modern techniques.Finally, the book emphasizes the potential for these methods to improve clinical decision-making, optimize personalized treatments, and design medical devices. The integration of advanced modeling and simulation techniques enhances the understanding of the complex mechanisms of joints, contributing significantly to both academic research and practical clinical applications.

  • Fungal Macromolecule Applications in Life Sciences

    Biological Activity and Medical, Industrial, and Agricultural Applications
    • 1st Edition
    • Jameel R. Al-Obaidi + 2 more
    • English
    Fungal Macromolecule Applications in Life Sciences: Biological Activity and Medical, Industrial, and Agricultural Applications provides a comprehensive guide to the diverse applications of fungal macromolecules, such as proteins, lipid carbohydrates, and nucleic acids. Chapters include an introduction to the background and importance of fungal macromolecules in various life science fields, followed by a detailed overview of the methods for isolating, characterizing, and assessing the structural and functional characteristics of fungal macromolecules.The book discusses the practical applications of fungal macromolecules in the biomedical, agricultural, and industry sectors. It explores potential uses of fungal macromolecules as pharmaceuticals, anti-cancer agents, and inhibitors of bacterial biofilm formation as well as in plant disease management, crop development, enzyme production, biosurfactants, and sustainable and functional food production. The book also examines the antimicrobial properties of fungal macromolecules and their role in managing disease and stimulating human immunology.This comprehensive and multidisciplinary coverage makes Fungal Macromolecule Applications in Life Sciences a valuable resource for scientists, professionals, and advanced students across various fields, including microbiology, biotechnology, biochemistry, pharmacology, agriculture, food science, and biomaterials, looking to enhance their understanding of fungal macromolecules in life sciences and bridge the gap between theory and practical application.

  • Regulated Cell Death in Neurodegenerative Disorders

    • 1st Edition
    • Heba Mohamed Mansour + 1 more
    • English
    Regulated Cell Death in Neurodegenerative Disorders is a comprehensive exploration of the mechanisms and implications of RCD within the realm of neurodegenerative diseases. The book delves into various forms of RCD such as apoptosis, necroptosis, ferroptosis, pyroptosis, and autophagy-mediated cell death, shedding light on their specific roles in disorders like Alzheimer’s, Parkinson’s, Multiple sclerosis, Amyotrophic lateral sclerosis, and Huntington’s. Written by leading experts, each chapter offers unique insights into cellular demise, providing valuable information on treatment options and therapeutic targets. The book features 14 chapters that cover molecular, cellular, and pharmacological mechanisms from an applied science perspective.Topics include the importance of chaperones, kinases, growth factors, inflammaging, mitochondrial dynamics, and oxidative stress. It presents targeted strategies to prevent cell death, reflecting ongoing pursuits in understanding and innovating treatments for neurodegenerative diseases. By offering therapeutic strategies to modulate RCD, this book not only shares knowledge but also provides hope for future advancements in combating these debilitating conditions.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 68
    • English
    Advances in Insect Physiology, Volume 68 in the series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Sections in this new release include The immune and non-immune defenses of aphids, Ecology, Evolution, and Mechanisms of Taste in Social Insects, Neuroendocrine regulation of Malpighian tubules, Tick gut physiology, and Drosophila/insect immunity.

  • Designer Poultry Eggs

    Innovations, Applications, and Future Outlook
    • 1st Edition
    • Arup Giri + 2 more
    • English
    Designer Poultry Eggs: Innovations, Applications, and Future Outlook serves as a comprehensive guide to the science and practical applications of improving egg quality. It explores cutting-edge methods for enriching eggs with omega-3 fatty acids, vitamins, and minerals, while simultaneously reducing cholesterol content. This book is ideal for food scientists, nutritionists, and poultry industry professionals who aim to meet consumer demands, improve egg production, and promote sustainable practices. Beyond nutrient enrichment, the book delves into the use of antioxidants and innovative production strategies to create healthier eggs.It also offers insights into future trends, market applications, and the growing role of designer eggs in addressing global nutritional challenges. With actionable knowledge and strategies, this resource empowers readers to adopt sustainable solutions for enhancing egg quality and overcoming production challenges.

  • Retinoids as Anti-cancer Agents in Breast Cancer

    A New Hope for Breast Cancer Treatment
    • 1st Edition
    • Manzoor Ahmad Mir
    • English
    Retinoids as Anti-cancer Agents in Breast Cancer: A New Hope for Breast Cancer Treatment offers a comprehensive overview of the latest research and advancements in using retinoids to treat breast cancer. The book delves into novel approaches, including drug combinations and the development of new pharmaceuticals. It provides an in-depth analysis of current treatment methods, highlighting both challenges and opportunities in the field. Topics covered include the principles and mechanisms of retinoids as anti-cancer agents, preclinical and clinical studies, and advancements in drug delivery systems and nano-formulations.Fu... research directions are also explored, emphasizing new drug combinations, biomarkers for patient selection, and personalized treatment strategies. This book will serve as a platform for students, researchers, oncologists, pharmacologists, and healthcare professionals who want to understand the potential of retinoids in clinical practice.

  • Insect Anatomy

    Structure and Function
    • 1st Edition
    • Bernard Moussian
    • English
    Insect Anatomy: Structure and Function provides both morphological and anatomical descriptions of insect tissues and organs and the underlying genetic mechanisms of their function using updated methods. Insects play important roles in diverse ecosystems, with subsequent, tremendous impacts on human society through disease, agriculture effects, and more. Both beneficial and detrimental insect species continuously challenge agriculture and medicine. Written by international experts of insect morphology and anatomy, this book offers concise descriptions of all parts of an insect’s anatomy, including the brain and nervous system, tracheal system, blood, reproductive organs, and kidney system.

  • Plastics in the Sea

    Occurrence and Impacts
    • 1st Edition
    • Sandra E. Shumway + 1 more
    • English
    Plastics in the Sea: Occurrence and Impacts is a comprehensive reference written by renowned leaders in the field. It synthesizes existing knowledge of how mega-, macro-, micro-, and nanoplastics impact marine environments and marine life, ranging from zooplankton, fishes, and invertebrates to birds, mammals, turtles, manatees, and other megafauna. The chapters provide basic and integrated discussions of the presence, sources, and fates; methodologies for detection, chemistry, and degradation; impacts on organisms and food webs; implications for fisheries and aquaculture; policy and public engagement; and economic and legal implications of plastic pollution. Plastics in the Sea: Occurrence and Impacts is an indispensable resource for marine resource managers, ecotoxicologists, fisheries stakeholders, policymakers, and academic researchers interested in the occurrence, impacts, and mitigation of marine plastic pollution.

  • Metagenomics for Microbiology

    • 2nd Edition
    • Jacques Izard + 1 more
    • English
    Metagenomics for Microbiology, Second Edition unveils the intricate and diverse world of microbial communities, emphasizing their critical roles in health, disease, and ecosystem functionality. This updated edition addresses the significant challenges in the field and introduces promising approaches to make metagenomics research more feasible. Through comprehensive revisions and over five new chapters, readers are equipped with the latest research data and analyses, advancing their understanding of microbial principles. Notably, this edition provides a robust foundation for the design and analysis of omics studies, focusing on technological underpinnings and practical applications. It remains an essential resource for characterizing microbial consortia.

  • Medicine in Homer

    • 1st Edition
    • Eric Altschuler
    • English
    Medicine in Homer explores injuries in the great epic poems of Homer from the perspective of contemporary medical professionals. This foundational text describes injuries included in both Odyssey and The Iliad, drawing on connections to neurology, toxicology, and genetics in ancient Greek times. As human anatomy remains unchanged, a careful study of trauma anatomy in Homer provides a unique window into the epics, their composition, and the development of medicine available today.

  • 100 Rare Tumors of the Digestive System

    A Case-Based Reference for Surgical Pathologists
    • 1st Edition
    • Xiaoyan Liao
    • English
    100 Rare Tumors of the Digestive System: A Case-Based Reference for Surgical Pathologists provides practicing surgical pathologists, gastroenterologists, oncologists, and surgeons with a comprehensive review on the clinical and pathologic features of rarely encountered neoplasms in the digestive system. The book uses a case-based format to cover typical clinical settings, including clinical history, symptoms, laboratory and radiographic findings, and representative histologic and immunologic pictures. This is the perfect reference for clinicians that would like to know more about updated terminology, histopathologic presentation, potential pathogenesis mechanisms, and treatment strategies for digestive disease entities.Scientists and researchers can also reference this book to find disease entities of interest, including pathogenesis, immunophenotype, and molecular findings. Multiple choice questioning is provided for readers to decide on the best diagnosis from a list of mimickers.

  • Healthcare Frontiers in the Metaverse

    Innovations and Impacts
    • 1st Edition
    • Shalli Rani
    • English
    Healthcare Frontiers in the Metaverse: Innovations and Impacts provides a deeper comprehension of the metaverse’s revolutionary effects on patient care, medical education, and operational procedures in the healthcare sector. This book Includes both the fundamentals of patient experience, provider practices, and the overall framework of the healthcare business as the democratization of medical education through virtual simulations and the individualized care enabled by AI-driven diagnostics. In 14 chapters, Healthcare Frontiers in the Metaverse: Innovations and Impacts leads the reader to an introduction to definition, elements, treatment and diagnostic in healthcare in metaverse, the next evolution in social connection, and the successor to the mobile internet. It describes the role of robots and give a view on the future scope and challenges. Healthcare Frontiers in the Metaverse: Innovations and Impacts serves as a road map for technologists and policymakers influencing the direction of healthcare as well as a help book for medical practitioners integrating metaverse technologies into their practice.

  • Biosafety Level 4 (BSL4) – Virus research at the highest level of biosafety and biosecurity

    • 1st Edition
    • Volume 122
    • English
    Advances in Virus Research, Volume 122 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including HERVs in cancer stem cells, Nomenclature for vertical, Modelling of vertically transmitted viruses, Vertical transmission of tomato viruses, and more.

  • Rabies

    Scientific Basis of the Disease and Its Management
    • 5th Edition
    • Alan C. Jackson + 1 more
    • English
    Rabies: Scientific Basis of the Disease and its Management, Fifth Edition is an authoritative reference that delves into the virological, clinical, and public health facets of rabies. This new edition provides insights into the molecular virology, pathogenesis, diagnosis, immunology, treatment, epidemiology, and public health strategies for managing rabies. It also includes discussions on the One Health approach to rabies, global implications, and setbacks due to the COVID-19 pandemic. Furthermore, the book serves as an essential resource for physicians, veterinarians, public health advisors, epidemiologists, and research scientists, offering current information on diagnosing, treating, controlling, and preventing this deadly infectious disease.

  • Cytokine-Based Immunotherapy - Part A

    • 1st Edition
    • Volume 396
    • English
    Cytokine-Based immunotherapy, Volume 396, Part A delves into the intricate world of cytokines, vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From their fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. The book includes chapters such as Cytokine-driven cancer immune evasion mechanisms, which explores how cytokines contribute to cancer cells' ability to evade the immune system. Cytokine-based immunotherapy in hematolymphoid malignancies is also explored, discussing the use of cytokines in treating blood cancers.Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.

  • Pain, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 43-3
    • Charles E. Argoff
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Charles E. Argoff brings his considerable expertise to the topic of Pain. Top experts discuss topics related primarily to non-headache pain, including a guide to assessing the person in pain, whether there is a role for acute or chronic opioid therapy; complex pelvic pain and its management; and many more.

  • Formulating and Implementing Pharmaceutical Pricing Policies

    Challenges, Case Studies and Lessons Learned from Medicine Price Control
    • 1st Edition
    • Zaheer-Ud-Din Babar
    • English
    Provides readers with a framework to understand and analyze several medicine pricing policies. Through case studies from countries across geographies and income tiers, this book explores the challenges and opportunities related to price control experiences. Studying global policies this book discusses approaches, strategies, and the underlying pharmaceutical pricing practices used to provide advice for formulating highly effective policies. Alongside the cases, this book covers appropriate research methods for pricing analysis, the essential components of pricing policy, data quality, and the generic structure of a pharmaceutical pricing policy.

  • Biosensing the Future

    Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part A
    • 1st Edition
    • Volume 215
    • English
    Biosensing the Future: Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring, Part A, Volume 215 offers a comprehensive exploration of biosensing technologies and their transformative impact on modern healthcare. Chapters in this new release include Technologies and emerging trends in wearable biosensing, Implantable biosensors: advancements and applications, Neural implants: restoring function and enhancing quality of life, Ingestible biosensors: monitoring health from within, Ingestible biosensors for monitoring digestive health and nutritional monitoring, and much more.Other chapters cover Ingestible biosensors for drug delivery monitoring, Artificial intelligence in wearable biosensing: enhancing data analysis and decision-making, Wearable Privacy, Ethical and regulatory landscape of wearable, ingestible, and implantable technologies, Characterization of skeletal muscle contraction using a flexible and wearable ultrasonic sensor, and more.

  • Immuno-oncology and Immunotherapy Part D

    • 1st Edition
    • Volume 196
    • English
    Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Investigating the endothelial-immune axis in cancer, Establishing Tyro3, Axl, and Mertk Chinese Hamster Ovary (CHO) Reporter Cell Lines for Cancer Immunology and Therapeutic Applications, Amino acid analog-based labelling of the immunomodulatory cancer secretome, Human and mouse iNKT cell expansion and engineering with viral vectors, Next-generation deconvolution of the tumor microenvironment with omnideconv, and much more.Additional sections cover Comprehensive prediction of tumor neoantigens with NextNEOpi, Ex vivo profiling of organotypic tumor spheroids in 3D microfluidic culture, A flow cytometry-based assay for evaluation of T cell activation and degranulation in coculture systems, An adenosine production assay suitable for 2D and 3D cancer cell culture, Determination of lactate in the tumor interstitial fluid, Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils, Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells, and much more.

  • The Neuroscience of Feelings: Brain-Heart Connectivity in Neurodegenerative Diseases

    • 1st Edition
    • Volume 294
    • English
    The Neuroscience of Feelings: Brain-Heart Connectivity in Neurodegenerative Diseases, Volume 294 explores the complex interplay between emotions and brain function+G147, covering topics such as The role of heart-brain connectivity in neurodegeneration: mechanisms and impacts, Cardiovascular influence on cognitive decline: the heart's role in neurodegenerative disorders, Autonomic nervous system dysregulation in neurodegenerative diseases: bridging brain and heart, Heart rate variability as an indicator of brain health in neurodegeneration, and much more.Other sections cover Emotional stress and cardiovascular health: impacts on neurodegenerative disease progression, Exploring heart-brain axis alterations in Parkinson’s disease, Cardiac biomarkers as predictors of cognitive decline in neurodegenerative conditions, Heart-brain synchrony: therapeutic implications for neurodegenerative disease, and Neurocardiology and neurodegenerative diseases: emerging research on emotional regulation and brain-heart connectivity.

  • Sustainability in the Manufacturing of Pharmaceuticals

    • 1st Edition
    • Dimitrios A. Lamprou
    • English
    Sustainability in Pharmaceutical Manufacturing is a groundbreaking reference for the pharmaceutical industry. Currently lagging behind other manufacturing sectors, pharmaceutical production requires significant changes in areas such as manufacturing methods, waste management, packaging, and supply chain. This book compiles cutting-edge research from leading global experts, offering scientific insights and innovative strategies to revolutionize sustainability in pharmaceuticals. It explores the transformative potential of the circular economy, lifecycle management, and resource optimization for maximum efficiency and minimal environmental impact.The book delves into green chemistry, highlighting alternative solvents and methods for drug production. It emphasizes novel microfluidic and additive manufacturing techniques, utilizing bio-based sustainable polymers and materials. Chapters on greener drug discovery, development, and scaling processes provide the most current research at each production stage. This invaluable resource enables researchers in academia and industry to make informed choices, enhancing their manufacturing practices and shaping the future of sustainability in the pharmaceutical sector.

  • New Developments in Redox Biology

    Fundamental Roles in Health and Disease
    • 1st Edition
    • Asim K. Duttaroy + 1 more
    • English
    New Developments in Redox Biology: Fundamental Roles in Health and Disease serves as a vital resource for understanding the profound impact of the redox system on human biology. In the book, readers are introduced to the intricate balance of oxidative stress, the delicate mechanisms of antioxidant defense, and their pivotal roles in cellular function. This book meticulously unpacks the connections between redox biology and the progression of health, aging, and disease, offering researchers and enthusiasts alike a window into these complex physiological processes.Aside from illuminating oxidative dynamics, this book delves into emerging trends, therapeutic potential, and the integration of redox principles in developing medical interventions, highlighting its relevance in advancing human health.

  • Myasthenia Gravis, Part A

    • 1st Edition
    • Volume 182
    • English
    Myasthenia Gravis, Part A, Volume 182 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as the Structure of the NMJ and Neuromuscular Transmission, Neuromuscular Junction and the Complement System, Regulation of the Autoimmune Response, The Thymus, Antibodies/Subclasse... (IgG) and Antigens, Cell Models of MG, Mouse Models of EAMG and Passive Immunization, Epidemiology of Myasthenia Gravis, Special Populations: Juvenile, Early, Late, and Very Late-Onset, Blood and Digital Biomarkers in MG, Lambert-Eaton Myasthenic Syndrome, and Congenital Myasthenic Syndromes.

  • Neurotoxicity of Solvents

    • 1st Edition
    • Volume 14
    • English
    Neurotoxicity of Solvents, Volume Fourteen highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers, An ecotoxicological view on solvents neurotoxicity, and The olfactory system as a target of solvent toxicity.

  • Enfermedad vascular cerebral en jóvenes

    • 1st Edition
    • Fernando Barinagarrementeria Aldatz + 1 more
    • Spanish
    Enfermedad vascular cerebral en jóvenes constituye una contribución inédita en lengua española sobre un tema tan específico como trascendente: la enfermedad vascular cerebral (EVC) en la población joven, escrita por autores internacionales líderes en los diferentes aspectos de este complejo tema. En las últimas décadas, la EVC en jóvenes ha dejado de ser una rareza clínica para convertirse en un problema creciente, con implicaciones significativas por lo que hace a su diagnóstico y manejo. El adecuado abordaje clínico y tecnológico es indispensable para la solución de esta compleja patología, y este título ofrece las herramientas necesarias para su estudio. La presente obra proporciona una revisión exhaustiva de los diferentes aspectos de la enfermedad, abordando su incidencia y factores de riesgo, tanto clásicos como nuevos. También se revisan las diferentes etiologías, y se proporciona un marco para la toma de decisiones clínicas y el manejo de los trastornos cerebrovasculares tanto frecuentes como infrecuentes en esta población.

  • Evapotranspiration in Agro-Ecosystems and Forestry

    Spatio-temporal Applications
    • 1st Edition
    • Suat Irmak
    • English
    Evapotranspiration in Agro-Ecosystems and Forestry: Spatio-temporal Applications presents the progress and advances made in terms of science and application of evaporation, transpiration, and evapotranspiration for various vegetation surfaces, water bodies, and bare soil under different soil and crop management (including different irrigation and tillage management) conditions. Sections on forest and wetlands evapotranspiration and grassland evaporative losses are included, as are the fundamentals of original Penman, Penman-Monteith, Shuttleworth-Wallace and ASCE-EWRI and FAO56 Penman-Monteith equations and their derivatives.The book is an excellent resource to better understand the progression and applications and dynamics of most recent evapotranspiration, evaporation and transpiration measurement and modeling technologies. Case studies will be provided in terms of how different technologies are currently deployed, how data are used for providing information and management decisions to the users.

  • Yarrowia Lipolytica Yeast

    From Metabolic Engineering to Biotechnological Applications
    • 1st Edition
    • Mohamed Koubaa + 2 more
    • English
    Yarrowia Lipolytica Yeast: From Metabolic Engineering to Biotechnological Applications gathers all the information about the genetics, uses, extraction, purification, and applications of this non-conventional yeast, not just focusing on the genetics and metabolic engineering, nor on its biotechnological applications. Chapters cover the genetic modifications and techniques used to genetically modify Y. Lipolytica, fermentation conditions, various media used in biotechnological applications, and all value-added compounds that can be produced. Edited by the most renowned researchers of this yeast, this book is of great interest to industries t working on biofuel production or searching for environmentally-frie... natural alternatives for their chemically produced value-added compounds.

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