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Books in Life sciences

  • Vesicle Trafficking in Eukaryotes

    • 1st Edition
    • Volume 93
    • English
    Current Topics in Membranes, Volume 93 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Receptor-mediated endocytosis in kidney cells during physiological and pathological conditions, Membrane transport and endocytosis in malaria parasites, Impact of Coat Protein on Evolution of Ilarviruses, and Membrane Contact Sites.
  • TRP Channels as Therapeutic Targets

    Advances in Basic Science and Clinical Use
    • 2nd Edition
    • Arpad Szallasi
    • English
    TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. Chapters are completely updated, withe new topics on TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. This is a great reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline will also find this book helpful for biologic principles of action.
  • Applied Multivariate Statistical Analysis in Medicine

    • 1st Edition
    • Jingmei Jiang
    • English
    Applied Multivariate Statistical Analysis in Medicine provides a multivariate conceptual framework that allows readers to understand the interconnectivity and interrelations among variables, which maintains the intrinsic precision of statistical theories. With a strong focus on the fundamental concepts of multivariate statistical analysis, the book also gives insight into the applications of multivariate distribution in biomedical fields. In 14 chapters, Applied Multivariate Statistical Analysis in Medicine covers the main topics of multivariate analysis methods widely used in health science research. The content is organized progressively from fundamental concepts to sophisticated methods. It begins with basic descriptive statistics in multivariate analysis and follows with parameter estimation, in addition to the hypothesis testing of a multivariate normal distribution, which has heavy applications in biomedical fields where the relationships among approximately normal variables are of great interest. Keeping mathematics to a minimum, considerable emphasis is placed on explanations and real-world applications of core principles to maintain a good balance between introducing theory and cultivating problem-solving skills. This book is a very valuable reference text for clinicians, medical researchers, and other researchers across medical and biomedical disciplines, all of whom confront increasingly complex statistical methods during the analysis and presentation of their results.
  • Principles of Immunotherapy in Breast and Gastrointestinal Cancers

    Activity, Mechanisms of Resistance and New Sensitization Strategies
    • 1st Edition
    • Michele Ghidini
    • English
    Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance, and New Sensitization Strategies presents updated research findings on immunotherapy, with a special focus on the mechanisms of resistance of those cancer types and how to overcome them.The book discusses topics such as tumor cell-intrinsic and -extrinsic mechanisms of cancer resistance to immunotherapy; the role of currently available biomarkers; strategies to overcome therapeutic resistance; sensitizing agents for cancer resistance to cell-mediated immunotherapy; and immunotherapeutic approaches, mechanisms of resistance, and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer.It is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it.
  • Neurologic Channelopathies

    • 1st Edition
    • Volume 203
    • English
    Neurological Channelopathies, Volume 203 begins with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations, but that also have potential for common treatment approaches, considering classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter considers Pathophysiological underpinnings - genetic or immunological; Clinical presentations; Diagnostic approach; and Treatment and management.In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological... and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the topics at hand.
  • Siderophore and Related Natural Products Biosynthesis

    • 1st Edition
    • Volume 702
    • English
    Methods in Enzymology Volume 702 highlights new advances in the field, with this new volume presenting interesting topics on Siderophore and related natural products biosynthesis
  • Imagerie des urgences neuroradiologiques

    • 1st Edition
    • François Cotton
    • French
    La survenue brutale d’un déficit neurologique oriente toujours vers la réalisation en urgence d’une imagerie du système nerveux central par scanner ou IRM. Cet examen est crucial pour la prise en charge thérapeutique du patient. Ce nouveau volume de la collection des « Syllabus de la SFR »(Société française de radiologie) et de la SFNR (Société française de neuroradiologie) propose ainsi un état de l’art de l’imagerie des urgences neuroradiologiques.C... ouvrage propose toute la sémiologie à connaître afin de pouvoir proposer la gamme diagnostique des urgences à rechercher. Il donne les clés pour privilégier la technique d’exploration la plus pertinente. Après un rappel des protocoles d’exploration en fonction des urgences, ou encore des éléments en vue de mieux comprendre la neuroradiologie interventionnelle, sont ainsi évoqués, entre autres, les accidents vasculaires cérébraux, les urgences traumatiques, infectieuses, métaboliques et toxiques, celles en fonction des régions (médullaire, orbitaire, etc.) ou en fonction des traitements sans oublier les spécificités pédiatriques, gériatriques et psychiatriques.Riche... illustré et complet, présenté de façon didactique et rédigé par les meilleurs experts en neuro-imagerie diagnostique et interventionnelle, cet ouvrage constitue la référence actuelle sur le sujet. Il est indispensable pour tous les radiologues confrontés aux urgences neuroradiologiques (vacations scanners ou IRM, permanence des soins, télémédecine) ainsi que pour les neurologues et neurochirurgiens qui prennent en charge ces patients.
  • Neuroscience of Coffee Part B

    • 1st Edition
    • Volume 289
    • English
    Neuroscience of Coffee, Volume 289 is a pioneering volume that delves into the intricate relationship between one of the world's most beloved beverages and the human brain. Offering a comprehensive exploration of the biochemical and physiological mechanisms underlying coffee's impact on the nervous system, this groundbreaking book transcends traditional coffee literature by focusing specifically on the neurological aspects. Chapters in this new release include Coffee and Parkinson's Disease, Coffee and Alzheimer's Disease, Coffee and Multiple Sclerosis (MS), Coffee and Amyotrophic lateral sclerosis (ALS), Exploring the Complex Relationship Between Caffeine Consumption and Schizophrenia: A Review of Epidemiological and Clinical Studies, and much more.Additional chapters explore Coffee, Antioxidants, and Brain Inflammation, Behavioral and Psychological Aspects of Coffee Consumption, From Bean to Brain: Coffee, Gray Matter, and Neuroprotection in Neurological Disorders Spectrum, and Synaptic Modulation by Coffee Compounds: Insights into Neural Plasticity.
  • Critical Heart Condition During Pregnancy

    Critical Care Obstetrics
    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Critical Heart Condition During Pregnancy, a volume in the Critical Care Obstetrics series, provides a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women with various health compromises specific to cardiac complications. The book's chapters reflect the growing scope of critical care obstetrics and the increasing importance and recognition of the hospital structure's field. All intensivists, regardless of primary discipline, must possess a core set of critical care skills that allow them to manage critically ill patients. The authors have gathered the best evidence-based material explicitly focused on cardiac scenarios.This volume presents cardiac medical-surgical complications that any patient can present during and post-partem, such as Arrhythmias, Endocarditis, Cardiogenic Shock, heart failure, and more.
  • Environmental Challenges in Attaining Food Security

    • 1st Edition
    • Volume 9
    • English
    Environmental Challenges in Attaining Food Security, Volume Nine in the Advances in Food Security and Sustainability series, highlights new advances in the field, with this new volume presenting interesting chapter on important topics such as Exacerbation of Food Insecurity in Africa: A Consequence of the Dual Threat of COVID-19 and the Russia-Ukraine Crisis; Rising Environmental Issues: A hindrance to food security; Microplastics in Soil and Water: Unveiling Environmental Risks and Implications; Emerging Contaminants – Categorization, Effect and Treatment; The Potential Impact on Pesticides on Insect Pollinators and Their Ecological Implications, and much more.Additional chapters cover Change in geo-environmental conditions and crop productivity; Pesticide Concentration and Its Impacts: Food security Vs. Food safety; Heavy metals in soil and water: Sources, fate, toxicology and remediation; Salinity stress in Crop Plants: Effects and Eco-friendly management; Salinity Stress: Impact on Plant Growth; Micronutrient bioavailability in contaminated soil and mitigation strategies for toxicity; Decrease in Arable Land and Water; and Nano-enabled sensor modules for detection of agrochemicals in diverse soil, and water systems: Progression and future trends; Monoculture Of Crops.