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Elsevier

Books in Life sciences

  • Health Data Processing

    Systemic Approaches
    • 1st Edition
    • Marius Fieschi
    • English
    Health Data Processing: Systemic Approaches focuses on the design of health information systems and touches on the main themes of medical informatics and public health. The book is written for health professionals in practice or training, and is especially useful for decision-makers or future decision-makers in the field of health information systems. Users will find sections on the question of reusing data for other purposes, protection of individual liberties that this data and technologies make more acute, and the irruption of large masses of genetic data and its related problems. This book develops the methodological and conceptual aspects related to these issues.

  • Safety Risk Management for Medical Devices

    • 1st Edition
    • Bijan Elahi
    • English
    Safety Risk Management for Medical Devices demystifies risk management, providing clarity of thought and confidence to the practitioners of risk management as they do their work. Written with practicing engineers, safety management professionals, and students in mind, this book will help readers tackle the difficult questions, such as how to define risk acceptance criteria and how to determine when to stop risk reduction. This book delivers not only theory, but also practical guidance for applying the theory in daily risk management work. The reader is familiarized with the vocabulary of risk management and guided through a process to ensure compliance with the international standard ISO 14971—a requirement for all medical devices. This book outlines sensible, easily comprehensible, and state-of the-art methodologies that are rooted in current industry best practices. Opening chapters introduce the concept of risk, the legal basis for risk management, and the requirements for a compliant risk-management process. The next group of chapters discusses the connection between risk management and quality systems, usability engineering and biocompatibility. This book delves into the techniques of risk management, such as fault tree analysis and failure modes and effects analysis, and continues with risk estimation, risk control, and risk evaluation. Special topics such as software risk management, clinical investigations, and security are also discussed. The latter chapters address benefit-risk analysis, and production and postproduction monitoring. This book concludes with advice and wisdom for sensible, efficient, and successful safety risk management of medical devices.

  • Microalgae in Health and Disease Prevention

    • 1st Edition
    • Ira Levine + 1 more
    • English
    Microalgae in Health and Disease Prevention is a comprehensive reference that addresses the historical and potential use of microalgae, its extracts, secondary metabolites, and molecular constituents for enhancing human health and preventing diseases. Each chapter features an overview, and the book includes coverage of microalgae biology, harmful algae, the use of microalgae in alcohol and food, and as sources of macronutrients, micronutrients, vitamins, and minerals. The historical use of microalgae, in addition to its potential use as a nutraceutical and cosmeceutical, is also addressed. The book provides coverage of relevant, up-to-date research as assembled by a group of contributors who are dedicated to the advancement of microalgae use in health, diet and nutrition.

  • Encyclopedia of Reproduction

    • 2nd Edition
    • Michael K. Skinner
    • English
    Encyclopedia of Reproduction, Second Edition, Six Volume Set comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field.

  • New Concepts in the Management of Septic Perianal Conditions

    • 1st Edition
    • Riyadh Mohammad Hasan + 1 more
    • English
    New Concepts in the Management of Septic Perianal Conditions provides a comprehensive review of the medically important basic and clinical aspects of perianal diseases in adults. This book presents current, medically important information in the rapidly changing field of anorectal diseases, including significant topics like perianal abscess and fistula. It provides an accurate source of clinically relevant information that is presented clearly and succinctly, making it perfect for the diagnosis, treatment and management of septic perianal conditions.

  • Mitosis and Meiosis Part B

    • 1st Edition
    • Volume 145
    • English
    Mitosis and Meiosis, Part B, Volume 145, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are chapters on Mitotic live cell imaging at different time scales, the characterization of mitotic spindle by multi-mode correlative microscopy, STED microscopy of mitosis, Correlating light microscopy with serial block face scanning electron microscopy to study mitotic spindle architecture, quantification of three-dimensional spindle architecture, Imaging based assays for mitotic chromosome condensation and dynamics, and more.

  • Cancer Nanotechnology

    • 1st Edition
    • Volume 139
    • English
    Advances in Cancer Research, Volume 139, provides invaluable information on the exciting and fast-moving field of cancer research. Original reviews are presented on a variety of topics relating to the rapidly developing intersection between nanotechnology and cancer research, with unique sections in the new release focusing on Exosomes as a theranostic for lung cancer, Nanotechnology and cancer immunotherapy, Ultrasound imaging agents and delivery systems, Dendronized systems for the delivery of chemotherapeutics, Thermosensitive liposomes for image-guided drug delivery, Supramolecular Chemistry in Tumor Analysis and Drug Delivery, Gold nanoparticles for delivery of cancer therapeutics, and Single cell barcode microchip for cancer research and therapy.

  • Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders

    • 1st Edition
    • Elizabeth B. Torres
    • English
    Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders provides a new and unifying methodological framework, introducing new objective biometrics to characterize patterns of sensory motor control underlying symptoms. Its goal is to radically transform the ways in which disorders of the nervous system are currently diagnosed, tracked, researched and treated. This book introduces new ways to bring the laboratory to the clinical setting, to schools and to settings of occupational and physical therapy. Ready-to-use, graphic user interfaces are introduced to provide outcome measures from wearable sensors that automatically assess in near real time the effectiveness of interventions. Lastly, examples of how the new framework has been effectively utilized in the context of clinical trials are provided.

  • Atlas of Hematopathology

    Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches
    • 2nd Edition
    • Faramarz Naeim + 3 more
    • English
    Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches, Second Edition, will appeal to both a wide range of people undergoing training in a variety of medical fields and practicing non-hematopathologis... For clinicians, fellows and residents, correct diagnosis (and therefore correct treatment) of diseases depends on a strong understanding of the molecular basis for the disease, making this book a crucial resource. This atlas contains hundreds of high-quality color images that mirror the findings that fellows and clinicians encounter in practice. In addition, it provides information in a quick, simple and user-friendly manner, attracting both those in training and non- experts. Residents, fellows, practicing clinicians, and researchers in pathology, hematology and hematology/oncology will find this a useful resource.

  • Epigenetics and Psychiatric Disease

    • 1st Edition
    • Volume 157
    • English
    Epigenetics and Psychiatric Disease, Volume 157, the latest volume in the Progress in Molecular Biology and Translational Science series, includes recent developments on a variety of topics, including the Epigenetic landscapes of the adversity-exposed brain, Chromosomal conformations and epigenomic regulation in schizophrenia, Progress in the epigenetics of depression, the epigenetics of circadian rhythms in imprinted neurodevelopmental disorders, DNA methylation mediating substance abuse, mechanisms and therapeutic opportunities, DNA methylation in animals model of psychosis, Epigenetics of early life stress, Epigenetic drugs for mood disorders, and more.

  • The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World

    • 1st Edition
    • Donald W. Duszynski + 2 more
    • English
    The fundamental concept of The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World is to provide an up-to-date reference guide to the identification, taxonomy, and known biology of apicomplexan intestinal and tissue parasites of carnivores including, but not limited to, geographic distribution, prevalence, sporulation, prepatent and patent periods, site(s) of infection in the definitive and (if known) intermediate hosts, endogenous development, cross-transmission, pathology, phylogeny, and (if known) their treatments. These data will allow easy parasite recognition with a summation of virtually everything now known about the biology of each parasite species covered. The last (very modest) and only treatise published on this subject was in 1981 so this book fills a fundamental gap in our knowledge of what is now known, and what is not, about the coccidian parasites that infect and sometimes kill carnivores and/or their prey that can harbor intermediate stages, including many domestic and game animals.

  • Marine enzymes and specialized metabolism - Part B

    • 1st Edition
    • Volume 605
    • English
    Marine enzymes and specialized metabolism - Part B, Volume 605 in the Methods in Enzymology series, highlights experimental methods on diverse marine enzymes involved in the construction of bioactive natural product molecules. Unique sections in this new release include discussions on polysaccharide-degra... enzymes from marine gastropods, radical SAM epimerases from sponge microbes, DMS/P demethylase in bacteria, reconstitution of particulate methane monooxygenase into membrane mimetics, the structure and function of cyanobactin enzymes, marine cyanobacterial polyketide beta-branching enzymology, marine cyanobacterial PKS-NRPS enzymology and structural biology, biochemical profiling of DMSP lyases, and more.

  • Transfusion Medicine for Pathologists

    A Comprehensive Review for Board Preparation, Certification, and Clinical Practice
    • 1st Edition
    • Brian Castillo + 4 more
    • English
    Transfusion Medicine for Pathologists: A Comprehensive Review for Board Preparation, Certification, and Clinical Practice is a concise study guide designed to complement standard textbooks in the field of clinical pathology. Pathology residents and fellows of transfusion medicine will find this book useful as a preparation tool for their exams. In addition, the book is a valuable timesaver for busy residents looking for a focused and compact study guide on transfusion medicine that will also be ideal for practicing pathologists who cross-cover transfusion medicine in their clinical practice.

  • Analytical Methods for Food Safety by Mass Spectrometry

    Volume I Pesticides
    • 1st Edition
    • Guo-Fang Pang
    • English
    Analytical Methods for Food Safety by Mass Spectrometry, Volume One: Pesticides systematically introduces the Pesticide and Veterinary Drug Multiresidues Analytical Methods. Volume One includes discussions on 20 pesticide multiresidues chromatic-MS (GC-MS and LC-MS/MS) analytical techniques that have the capability of detecting over 800 pesticides and chemicals in 10 categories of agricultural products, including fruits, vegetables, grains, teas, Chinese medicinal herbs, edible fungus mushrooms, fruit and vegetable juices, animal tissues, aquatic products, raw milk and milk powders, and drinkable water. This book also includes chromatic-MS analytical parameters, linear equations and GPC chromatic behavior parameters for over 800 pesticides. This valuable book can be used as reference for not only university students, but also technical personnel of different specialties who are engaged with study and applications, such as food safety, agricultural environment protection, pesticide development, and utilization in scientific research units, institutions and quality inspection organizations.

  • Fibroblast Growth Factors

    • 1st Edition
    • Xiaokun Li
    • English
    Fibroblast Growth Factors presents research and results from the leading global research group on FGF, providing up-to-date and comprehensive coverage of the field. The book describes the history, basic research and growth engineering technology involved with FGFs, while also introducing detailed research methods. It comprises eight chapters that detail successes and problems in relation to wound healing of engineered growth factors and considers injury repair and regeneration, non-mitogenic mutants, structure modification, pathology, physiology, pharmacology, development, FGF/FGFR inhibitors, bioengineering, and new drug development. It will serve as a key reference book for researchers working on FGFs.

  • Food Fortification in a Globalized World

    • 1st Edition
    • M.G.Venkatesh Mannar + 1 more
    • English
    Food Fortification in a Globalized World outlines experiences over the past 50 years—and future potential—for the application of food fortification across a variety of foods in the industrialized and developing world. The book captures recent science and applications trends in fortification, including emerging areas such as biofortification, nutraceuticals and new nutrient intake recommendations, standards, policy and regulation. The book proposes a balanced and effective food fortification strategy for nations to adopt. In covering the most technical scientific details in an approachable style, this work is accessible to a range of practitioners in industry, government, NGOs, academia and research. Food fortification has become an increasingly significant strategy to address gaps in micronutrient intakes in populations with measurable impact in both industrialized and developing countries. While the positive impacts are well recognized there are new concerns in some countries that excessive fortification of foods, outdated nutritional labeling rules and misleading marketing tactics used by food manufacturers may result in young children consuming harmful amounts of some vitamins and minerals.

  • Studies on Hepatitis Viruses

    Life Cycle, Structure, Functions, and Inhibition
    • 1st Edition
    • Satya Prakash Gupta
    • English
    Studies on Hepatitis Viruses: Life Cycle, Structure, Functions, and Inhibition presents the latest on this systemic infection that predominantly affects the liver with inflammation that can be acute or chronic. Hepatitis viruses have been the subject of intense study in the last twenty years, with a wealth of information related to their lifecycle, structure, functions and inhibition being presented. This book compiles the most important developments and research, giving users a very useful guide on this evolving area of virology and medicinal chemistry.

  • Genomic Medicine in Emerging Economies

    Genomics for Every Nation
    • 1st Edition
    • George P. Patrinos + 1 more
    • English
    Originally thought to be available only to the world’s wealthiest nations, genomic medicine has developed into a broad range of clinical methods and technologies whose concrete applications are also revolutionizing health systems in many of the world’s resource-limited nations. Genomic Medicine in Emerging Economies: Genomics for Every Nation provides in-depth analysis and key examples of the implementation of medical genomics in low-income nations across the globe, demonstrating how this advancing medical science has already transformed health systems and led to improved patient care in Indonesian, Chilean, Malaysian, Argentinian, Chinese, Sri Lankan, and Colombian populations among others. In addition to defining tools, diagnostics, and treatment pathways at the population-wide level for medical geneticists, genomic researchers, and public health workers to apply in their own work, this book offers an essential, case-study based approach needed to understand how genomic medicine can be used to improve disease-management in a diverse range of economic and social contexts.

  • The Neuroscience of Empathy, Compassion, and Self-Compassion

    • 1st Edition
    • Larry Charles Stevens + 1 more
    • English
    The Neuroscience of Empathy, Compassion, and Self-Compassion provides contemporary perspectives on the three related domains of empathy, compassion and self-compassion (ECS). It informs current research, stimulates further research endeavors, and encourages continued and creative philosophical and scientific inquiry into the critical societal constructs of ECS. Examining the growing number of electrocortical (EEG Power Spectral, Coherence, Evoked Potential, etc.) studies and the sizeable body of exciting neuroendocrine research (e.g., oxytocin, dopamine, etc.) that have accumulated over decades, this reference is a unique and comprehensive approach to empathy, compassion and self-compassion.

  • Post-Authorization Safety Studies of Medicinal Products

    The PASS Book
    • 1st Edition
    • Ayad K. Ali + 1 more
    • English
    Post-Authorization Safety Studies of Medicinal Products: The PASS Book bridges the gap in the literature by providing a complete look at post-authorization safety studies and important pharmacoepidemiology and pharmacovigilance aspects. It covers various types and limitations of active surveillance programs, including the use of large databases and disparate data sources for rapid signal detection, as well as novel and advanced design and analysis approaches for causal interference from observational data. This book serves as an important reference for pharmacovigilance scientists and pharmacoepidemiologi... who are searching for the appropriate study design to answer safety research questions. Readers will be able to effectively and efficiently design and interpret findings from post-authorization safety studies with the goal of improving the benefit-risk balance of a drug in order to optimize patient safety.

  • Asiatic Liver Fluke - From Basic Science to Public Health, Part A

    • 1st Edition
    • Volume 101
    • English
    Asiatic Liver Fluke - From Basic Science to Public Health, Volume 101, is a well-known and respected outlet for detailed and comprehensive reviews written by experts covering all aspects of parasitology. This latest release covers topics of interest, including the Taxonomy, ecology and population genetics of Opisthorchis viverrini and its intermediate hosts, the Epidemiology, geospatial analysis of Opisthorchis viverrini infection and climate change effects in the Mekong basin, Reservoir species and transmission of Opisthorchis viverrini, The draft genome of Opisthorchis viverrini, Functional genomics and genetic manipulation of Opisthorchis viverrini, Microbiomes and liver fluke infection, and more.

  • Applications of Nanocomposite Materials in Drug Delivery

    • 1st Edition
    • Inamuddin + 2 more
    • English
    Applications of Nanocomposite in Drug Delivery discusses and explores the applications of nanocomposites in the area of drug delivery. Starting with a scientific understanding of drug delivery fundamentals, the book explores the utility of nanocomposites in the area of controlled, transdermal, osteo-articular tuberculosis and stimulus sensitive drug delivery applications. The book intricately details and discusses a variety of methods for their preparation, while also highlighting specific applications of nanocomposites in targeted drug delivery.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 103
    • English
    Advances in Applied Microbiology, Volume 103, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters on antimicrobial resistance in Campylobacter species, microbial source tracking, modeling phage bacteria interactions, and bacterial anaerobic synthesis gas (syngas) and CO2 + H2 fermentation. Each eclectic volume in this series is supplemented by thematic volumes in areas such as Archaea and sick building syndrome.

  • Environmental Virology and Virus Ecology

    • 1st Edition
    • Volume 101
    • English
    Environmental Virology, Volume 101, the latest in the Advances in Virus Research series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Updates to this release include sections on the host landscape and vector behavior, key determinants of plant virus evolution and emergence, plant virome analysis using spatial metagenomics, host range evolution in generalist viruses, the influence of environment, water-mediated spread and transmission of viruses, viruses transmitted by means other than insect vectors, and more.

  • Hemophilia and Von Willebrand Disease

    Factor VIII and Von Willebrand Factor
    • 1st Edition
    • David Green
    • English
    Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor serves as a must-have reference on the important role these essential blood-clotting proteins play in research and clinical medicine. Clinicians and researchers face the daily challenge of staying current on the vast amounts of research that is now generated. The reference to Janus in the title refers to the two roles of the Factor VIII/Von Willebrand Factor Complex: initiation of coagulation and propagation of clot formation. The complex prevents bleeding in hemophilia and Von Willebrand disease but also augments arterial and venous thrombosis.

  • Perinatal Stem Cells

    Research and Therapy
    • 1st Edition
    • Anthony Atala + 4 more
    • English
    Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry.

  • Ancestral DNA, Human Origins, and Migrations

    • 1st Edition
    • Rene J. Herrera + 1 more
    • English
    Ancestral DNA, Human Origins, and Migrations describes the genesis of humans in Africa and the subsequent story of how our species migrated to every corner of the globe. Different phases of this journey are presented in an integrative format with information from a number of disciplines, including population genetics, evolution, anthropology, archaeology, climatology, linguistics, art, music, folklore and history. This unique approach weaves a story that has synergistic impact in the clarity and level of understanding that will appeal to those researching, studying, and interested in population genetics, evolutionary biology, human migrations, and the beginnings of our species.

  • An Overview of FDA Regulated Products

    From Drugs and Cosmetics to Food and Tobacco
    • 1st Edition
    • Eunjoo Pacifici + 1 more
    • English
    Approx.270 pages

  • Biochemical, Physiological and Molecular Avenues for Combating Abiotic Stress in Plants

    • 1st Edition
    • Shabir Hussain Wani
    • English
    Biochemical, Physiological and Molecular Avenues for Combating Abiotic Stress in Plants is a must-have reference for researchers and professionals in agronomy, plant science and horticulture. As abiotic stress tolerance is a constant challenge for researchers and professionals working on improving crop production, this book combines recent advances with foundational content, thus offering in-depth coverage on a variety of abiotic stress tolerance mechanisms that help us better understand and improve plant response and growth under stress conditions. The mechanisms explored in this book include stress perception, signal transduction and synthesis of stress-related proteins and other molecules. In addition, the book provides a critical understanding of the networks of genes responsible for abiotic stress tolerance and their utilization in the development of stress tolerance in plants. Practical breeding techniques and modern genetic analyses are also discussed.

  • The Cellular Secretome and Organ Crosstalk

    • 1st Edition
    • Juergen Eckel
    • English
    The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development.

  • Edible Oleogels

    Structure and Health Implications
    • 2nd Edition
    • Alejandro G. Marangoni + 1 more
    • English
    Edible Oleogels, Structure and Health Implications, Second Edition presents a novel strategy on how to eliminate trans fats from our diets. Topics covered include how to avoid excessive amounts of saturated fat by structuring oil to make it behave like crystalline fat and how to develop trans fat free, low saturate, functional shortenings for the food industry. The major approach to form these materials is covered, helping manufacturers incorporate specific molecules (polymers, amphiphiles, waxes) into oil components. As such, this an ideal resource for those in product development and anyone interested in understanding the role of trans and saturated fats in health and nutrition. In an effort to provide alternatives to trans and saturated fats, scientists have been busy modifying the physical properties of oils to resemble those of fats. Many food products requiring a specific texture and rheology can be made with these novel oil-based materials without causing significant changes to final product quality. Hence, this book provides a valuable resource on new advancements.

  • Structure-Function Analysis of Edible Fats

    • 2nd Edition
    • Alejandro G. Marangoni
    • English
    Structure-Function Analysis of Edible Fats, Second Edition summarizes the latest approaches in the quantification of the physical structure of fats and its relationship to macroscopic functionality. The book takes a proven, general approach, presenting principles and techniques in a way that can be applied to any lipidic material. As the maturity of the field has increased since the first edition, there is an increased need for more sophisticated quantitative approaches to common problems encountered by industry. This book outlines modern methods used for this purpose by some of the leading authorities in the field today. Edited by expert Alejandro Marangoni, and with contributions from leaders in field, the book features the latest developments, including chapters on Phase Behavior of Fat Mixtures and the Rheology and Mechanical Properties of Fats Methods Used in the Study of the Physical Properties of Fats (including a new section on microscopy).

  • Bipolar Disorder Vulnerability

    Perspectives from Pediatric and High-Risk Populations
    • 1st Edition
    • Jair Soares + 2 more
    • English
    Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.

  • Applied Biomechatronics Using Mathematical Models

    • 1st Edition
    • Jorge Garza Ulloa
    • English
    Applied Biomechatronics Using Mathematical Models provides an appropriate methodology to detect and measure diseases and injuries relating to human kinematics and kinetics. It features mathematical models that, when applied to engineering principles and techniques in the medical field, can be used in assistive devices that work with bodily signals. The use of data in the kinematics and kinetics analysis of the human body, including musculoskeletal kinetics and joints and their relationship to the central nervous system (CNS) is covered, helping users understand how the complex network of symbiotic systems in the skeletal and muscular system work together to allow movement controlled by the CNS. With the use of appropriate electronic sensors at specific areas connected to bio-instruments, we can obtain enough information to create a mathematical model for assistive devices by analyzing the kinematics and kinetics of the human body. The mathematical models developed in this book can provide more effective devices for use in aiding and improving the function of the body in relation to a variety of injuries and diseases.

  • The Paracellular Channel

    Biology, Physiology, and Disease
    • 1st Edition
    • Jianghui Hou
    • English
    The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization.

  • The Cerebellum: Disorders and Treatment

    Handbook of Clinical Neurology Series
    • 1st Edition
    • Volume 155
    • English
    The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies.

  • Bioinformatics Algorithms

    Design and Implementation in Python
    • 1st Edition
    • Miguel Rocha + 1 more
    • English
    Bioinformatics Algorithms: Design and Implementation in Python provides a comprehensive book on many of the most important bioinformatics problems, putting forward the best algorithms and showing how to implement them. The book focuses on the use of the Python programming language and its algorithms, which is quickly becoming the most popular language in the bioinformatics field. Readers will find the tools they need to improve their knowledge and skills with regard to algorithm development and implementation, and will also uncover prototypes of bioinformatics applications that demonstrate the main principles underlying real world applications.

  • The Cerebellum: From Embryology to Diagnostic Investigations

    Handbook of Clinical Neurology Series
    • 1st Edition
    • Volume 154
    • English
    The Cerebellum: From Embryology to Diagnostic Investigations, Volume 154 is designed to update the reader on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Embryology, Anatomy and Function, and (2) Diagnostic investigations: Neuroimaging, and includes content on conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Its companion volume, The Cerebellum: Disorders and Treatment, describes disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice and therapy (including insights into innovative drug and rehabilitative approaches to treat children and adults with cerebellar disorders).

  • Human Prion Diseases

    • 1st Edition
    • Volume 153
    • English
    Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems.

  • Antimicrobial Peptides in Gastrointestinal Diseases

    • 1st Edition
    • Chi Hin Cho
    • English
    Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract.

  • The Physiology of Physical Training

    • 1st Edition
    • Zsolt Radák
    • English
    The Physiology of Physical Training provides complete coverage of the physiological and methodological aspects of physical training, providing essential knowledge for anyone involved in exercise physiology. Physiological processes at the cellular level (and for the whole organism) are covered to better explain particular training methods and convey a deeper knowledge and understanding of training techniques. Coverage of exercise training-induced adaptive responses and the most appropriate training methods to bring about targeted adaptive changes are also included. This is the perfect reference for researchers of physiology/kinesiolo... and human kinetics, practicing coaches, graduate students and sports medicine specialists.

  • An Atlas of Comparative Vertebrate Histology

    • 1st Edition
    • Donald B. McMillan + 1 more
    • English
    Atlas of Comparative Vertebrate Histology looks at the histology of a wide range of vertebrates, representative of all the major classes and families, with examples ranging from amphioxus to primates. The authors focus their microscope on commonly seen vertebrates as well as ‘non-standard’ species, such as lamprey, hagfish, dogfish, skate, rock bass, cod, river catfish, toad, amphiuma, leopard and bull frog, garter and brown snake, Coturnix quail and cowbird. The study of comparative histology in the vertebrates helps students and researchers alike understand how various groups have addressed similar problems, opening doors to interesting research possibilities. Not all vertebrates follow the mammalian model of tissue and organ structure. When dealing with unique species, we see some structures taken beyond their ‘normal’ function. Comparative histology allows us to understand the structural responses underlying the physiology unique to each vertebrate group.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 85
    • English
    Advances in Food and Nutrition Research, Volume 85, provides updated knowledge on nutrients in foods and how to avoid their deficiency, especially the essential nutrients that should be present in the diet to reduce disease risk and optimize health. The book provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits. Readers will find up-to-date information on food science, including raw materials, production, processing, distribution and consumption, with an emphasis on nutritional benefits and health effects. New sections in the updated volume include discussions on the biological and biomedical applications of egg peptides, omega-3 fatty acids and liver diseases in children, the characterization of the degree of food processing in relation to health, the impact of unit operations from farm to fork on microbial safety and quality of foods, new trends in the uses of yeasts in oenology, and more.

  • Planning for a Career in Biomedical and Life Sciences

    Learn to Navigate a Tough Research Culture by Harnessing the Power of Career Building
    • 2nd Edition
    • Avrum I. Gotlieb
    • English
    Planning for a Career in Biomedical and Life Sciences:Learn to Navigate a Tough Research Culture by Harnessing the Power of Career Building, Second Edition, presents useful information, insights and tips to those pursuing a career in the biomedical and life sciences. The book focuses on making educated choices during schooling, training, and the job search in both the academic and non-academic sectors. The book's premise lies in the notion that if users understand the full path of a career in either the biomedical or life science fields, they can proactively plan their career, recognize any opportunities that present themselves, and be well prepared to address important aspects of their own professional development.Topics include choosing a training path, selecting the best supervisor/mentor, and negotiating a job offer. Updates to this edition include an outline of core competencies to achieve success, how to build soft skills and tailor them to specific job opportunities, and how to increase collaborations across disciplines. Additionally, coverage on issues around diversity, health, wellness and work/life balance are expanded. This book is a valuable resource for undergraduate, graduate, medical and postdoctoral students in the biomedical and life sciences, as well as academic faculty and advisors.

  • Chikungunya and Zika Viruses

    Global Emerging Health Threats
    • 1st Edition
    • Stephen Higgs + 2 more
    • English
    Chikungunya and Zika Viruses: Global Emerging Health Threats is the go-to resource for both historical and current information on this important virus that is rapidly increasing its global range. Epidemics since 2005 have spread from Africa and Asia, and through Europe, and an ongoing epidemic has caused nearly two million cases in the Americas. It causes severe crippling arthritis, with symptoms lasting for months or years. As no vaccine or treatment is available, there is international interest in the virus, thus funding opportunities for research have dramatically increased. This book presents our understanding of the virus, bringing comprehensive knowledge in a single source.

  • Smart Wheelchairs and Brain-computer Interfaces

    Mobile Assistive Technologies
    • 1st Edition
    • Pablo Diez
    • English
    Smart Wheelchairs and Brain-Computer Interfaces: Mobile Assistive Technologies combines the fields of neuroscience, rehabilitation and robotics via contributions from experts in their field to help readers develop new mobile assistive technologies. It provides information on robotics, control algorithm design for mobile robotics systems, ultrasonic and laser sensors for measurement and trajectory planning, and is ideal for researchers in BCI. A full view of this new field is presented, giving readers the current research in the field of smart wheelchairs, potential control mechanisms and human interfaces that covers mobility, particularly powered mobility, smart wheelchairs, particularly sensors, control mechanisms, and human interfaces.

  • Human Resilience Against Food Insecurity

    • 1st Edition
    • John Michael Ashley
    • English
    Human Resilience against Food Insecurity focuses on the human factors involved in building resilience against food and nutrition insecurity in perpetuity through better managing risks (such as ‘better-spacing’ of children), diversifying the asset portfolio, behavioral change, and communication strategies for to help achieve these goals. The better the coherence and convergence amongst these human factors that promote sustainable food and nutrition security, the lower the need to rectify their absence through post-facto, unsustainable ‘firemen’s work’ of humanitarian assistance and CMAM clinics. The book includes references to countries which are not in the lowest of the categories prescribed in the UNDP Human Development reports, also including minority groups in developed countries, such as the hunter-gatherer Inuit communities of Canada, to provide an inclusive view of the issues and concerns relevant to addressing food insecurity.

  • Human Parasitology

    • 5th Edition
    • Burton J. Bogitsh + 2 more
    • English
    Human Parasitology, Fifth Edition emphasizes a medical perspective that also incorporates functional morphology, physiology, biochemistry and immunology to enhance appreciation of the diverse implications of parasitism. Bridging the gap between classical clinical parasitology texts and traditional encyclopedic treatises, the book will not only appeal to students interested in the medical aspects of parasitology, but also those who are interested in gaining a solid foundation in the biology of parasites. This updated edition has been fully revised to integrate the most recent molecular discoveries about mosquitoes, ticks and other arthropods as vectors, along with the most effective therapeutic regimens for each.

  • Extracellular Matrix and Egg Coats

    • 1st Edition
    • Volume 130
    • English
    Extracellular Matrix and Egg Coats, Volume 130, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on The Human Egg’s Zona Pellucida, the Structure of Zona Pellucida Module Proteins, The Fish Egg’s Zona Pellucidam The Chicken Egg’s Zona Pellucidam The Marsupial Egg’s Zona Pellucida, the Evolution of Zona Pellucida Proteins, The Mouse Egg’s Zona Pellucida, Aspects of ECM, ECM and Morphogenesis, Collagen fibril assembly and function, The Ear's Tectorial Membrane, ECM and Cell Fate, and the Aspects of ECM.

  • Human Microbiota in Health and Disease

    From Pathogenesis to Therapy
    • 1st Edition
    • Bryan Tungland
    • English
    Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion of all the aspects associated with gut microbiota early colonization, its development and maintenance, and its symbiotic relationship with the host to promote health. Chapters illustrate the complex mechanisms and metabolic signalling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, while mediating inflammatory processes involved in the etiology of many chronic disease conditions. Details are provided on the primary etiological factors of chronic disease, the effects of gut dysbiosis and its associated disease conditions, while providing an overview of therapeutic strategies involving dietary fiber and prebiotics, fecal microbiota transplantation therapy and probiotics. Throughout the chapters, a comprehensive review of peer-reviewed animal and human studies is provided as evidence related to the history of human exposure, safety, tolerance, toxicity, nomenclature, and clinical efficacy of utilizing prebiotic fructans, s, as well as probiotic intervention, and dietary modification in the prevention and intervention of chronic disease conditions. With common use today of pharmaceutical medicine in treating symptoms, and frequent overuse of antibiotics in chronic disease within mainstream medical practice, understanding the etiological mechanisms of dysbiosis-induced chronic disease, and natural approaches that offer prevention and potential cures for these diseases is of vital importance to overall human health.

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