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Elsevier

Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

  • Lead

    Chemistry, Analytical Aspects, Environmental Impact and Health Effects
    • 1st Edition
    • José S. Casas + 1 more
    • English
    Lead covers the salient aspects of the chemistry of lead, its environmental impact, and its effects on health. The technical, economic and social importance of Lead, at the present time, is beyond all doubt. However, over the last few decades little attention has been given to its behaviour (the properties and applications of its compounds, the environmental distribution of these derivatives, and their impacts on living creatures), this book addresses that gap. It includes coverage of historical aspects, lead mining and production, metal properties, common lead compounds, uses of lead and its derivatives, coordination chemistry, organometallic chemistry, environmental chemistry, toxicity mechanisms, and treatment strategies for lead poisoning. Finally, describing analytical procedures for the determination of lead in chemical, biological and environmental samples.

  • Hazardous Substances and Human Health

    Exposure, Impact and External Cost Assessment at the European Scale
    • 1st Edition
    • Volume 8
    • Till M Bachmann
    • English
    There is widespread public concern about hazardous chemicals that are contained in air, soil, water and food. Policy has therefore adopted a series of laws and regulations concerning emissions into and concentration levels in different media including food. As policy makers do not only have to consider the protection of the environment but also need to ensure a well-functioning economy at the same time, these limit or target values need to be set in a balanced way. The main problem, however, is to compare the costs for achieving these targets with the benefits to society by having a smaller exposure to hazardous substances (cost-benefit analysis). This book sets out to improve the reliability of cost-benefit analyses particularly of hazardous substances present in air, water, soil and food. It suggests that the human health risk assessment of chemicals is performed in a bottom-up analysis, i.e., following a spatially resolved multimedia modelling approach. In order to support cost-benefit analyses, the approach is accompanied by monetary valuation of human health impacts, yielding so-called external costs. Results for selected priority metals show that these external costs are small compared to those by the classical air pollutants and involve rather long time horizons touching on the aspect of intergenerational equity within sustainable development. When including further hazardous substances, the total external costs attributable to contaminants are expected to be more substantial.

  • Encyclopedia of Toxicology

    • 2nd Edition
    • Bruce Anderson + 9 more
    • English
    The second edition of the Encyclopedia of Toxicology continues its comprehensive survey of toxicology. This new edition continues to present entries devoted to key concepts and specific chemicals. There has been an increase in entries devoted to international organizations and well-known toxic-related incidents such as Love Canal and Chernobyl. Along with the traditional scientifically based entries, new articles focus on the societal implications of toxicological knowledge including environmental crimes, chemical and biological warfare in ancient times, and a history of the U.S. environmental movement. With more than 1150 entries, this second edition has been expanded in length, breadth and depth, and provides an extensive overview of the many facets of toxicology.Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedire...

  • Handbook of Forensic Drug Analysis

    • 1st Edition
    • Fred Smith
    • English
    The Handbook of Forensic Drug Analysis is a comprehensive chemical and analytic reference for the forensic analysis of illicit drugs. With chapters written by leading researchers in the field, the book provides in-depth, up-to-date methods and results of forensic drug analyses. This Handbook discusses various forms of the drug as well as the origin and nature of samples. It explains how to perform various tests, the use of best practices, and the analysis of results. Numerous forensic and chemical analytic techniques are covered including immunoassay, gas chromatography, and mass spectrometry. Topics range from the use of immunoassay technologies for drugs-of-abuse testing, to methods of forensic analysis for cannabis, hallucinogens, cocaine, opioids, and amphetamine. The book also looks at synthetic methods and law enforcement concerns regarding the manufacture of illicit drugs, with an emphasis on clandestine methamphetamine production. This Handbook should serve as a widely used reference for forensic scientists, toxicologists, pharmacologists, drug companies, and professionals working in toxicology testing labs, libraries, and poison control centers. It may also be used by chemists, physicians and those in legal and regulatory professions, and students of graduate courses in forensic science.

  • Pesticide, Veterinary and Other Residues in Food

    • 1st Edition
    • David Watson
    • English
    This wide-ranging text reviews the wealth of recent research on assessing and managing the risks from pesticide, veterinary and other chemical residues in food. After an introductory chapter on the key issues in food toxicology,Part one covers the assessment and management of risks, with individual chapters on genetic susceptibility to dietary carcinogens, good agricultural practice and HACCP systems, targeted and rapid methods for analysing residues in food and ways of assessing the mutagenicity of chemicals in food. Part two looks at veterinary residues, covering their safety, toxicology and detection. Part three examines pesticides, with chapters on surveillance and detection methods for fungicides and herbicides. In the final part, there are chapters summarising a wide range of other chemical residues in food, from xenostrogens/endocri... disruptors and dietary estrogens to polycyclic aromatic hydrocarbons, dioxins and polychlorinated biphenyls.Pesticide, veterinary and other residues in food is a standard reference for all those concerned with ensuring the safety of food.

  • Mycotoxins in Food

    Detection and Control
    • 1st Edition
    • N Magan + 1 more
    • English
    Mycotoxins, toxic compounds produced by fungi, pose a significant contamination risk in both animal feed and foods for human consumption. With its distinguished editors and international team of contributors, Mycotoxins in food summarises the wealth of recent research on how to assess the risks from mycotoxins, detect particular mycotoxins and control them at differing stages in the supply chain.Part one addresses risk assessment techniques, sampling methods, modelling and detection techniques used to measure the risk of mycotoxin contamination and the current regulations governing mycotoxin limits in food. Part two looks at how the risk of contamination may be controlled, with chapters on the use of HACCP systems and mycotoxin control at different stages in the supply chain. Two case studies demonstrate how these controls work for particular products. The final section details particular mycotoxins, from ochratoxin A and patulin to zearalenone and fumonisins.Mycotoxin... in food is a standard reference for all those concerned with ensuring the safety of food.

  • Teratology in the Twentieth Century

    Congenital Malformations in Humans and How their Environmental Causes were Established
    • 1st Edition
    • H. Kalter
    • English
    This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment.

  • Hallucinogens

    A Forensic Drug Handbook
    • 1st Edition
    • Richard Laing
    • English
    Hallucinogens: A Forensic Drug Handbook is a comprehensive reference for everyone involved in the identification, investigation, and forensic analysis of hallucinogenic drugs. The text begins with a review of the history of these drugs and their abuse, and then takes an in-depth look at the many different types of hallucinogens, their chemical make-up, how they affect users, how they are manufactured and distributed, and how they can be detected and analyzed.Hallucinoge... covers the most commonly abused drugs such as LSD, MDMA ("Ecstasy"), and PCP ("Angel Dust"), as well as many lesser-known chemical substances that cause similar effects. Chapters have been contributed by leading analysts and investigators around the world, and are highlighted with numerous illustrations. This unique handbook will serve is a cross-disciplinary source of information for forensic toxicologists, law enforcement officers, and others involved in the fight against drugs.

  • Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens

    • 1st Edition
    • Richard P. Pohanish
    • English
    The fourth edition of this classic reference by Marshall Sittig presents expansive chemical, health, and safety data for over 1,500 chemicals in the plastics, pharmaceuticals/biot... energy, cleaning solvents, agriculture and other industries. The chemicals are presented alphabetically and classified as a carcinogen, hazardous substance, hazardous waste, or toxic pollutant. Chemical data cover description, exposure limits, harmful effects, first aid, and storage among the other important information included to make appropriate response decisions. Highlights of the expanded information include:• A comprehensive CAS index with the new US, CAS, and RTECS numbers and the DOT ID for all chemicals listed.• The EEC and EINECS international numbers.• International regulatory authority references (US, Canada, Mexico, Europe; federal and local levels).• Chemical formulas.• Detailed physical properties data.• Chemical incompatibility information.• Information about medical surveillance, respirator requirements, first aid, spill, fire and emergency response (including initial isolation and protection action distances), and disposal requirements.• Greatly expanded chemical synonym and trade-name indexes, including international names.• User-friendly synonym listings with cross-references tied to the primary (generic) name.

  • Cellular and Molecular Toxicology

    Volume 14
    • 1st Edition
    • J.P. Vanden Heuvel + 3 more
    • English
    Volume 14 in the series Comprehensive Toxicology extends and complements the previously published 13-volume set. This volume will be available separately.Toxicolog... is the study of the nature and actions of chemicals on biological systems. In more primitive times, it really was the study of poisons. However, in the early 1500s, it was apparent to Paracelsus that "the dose differentiates a poison and a remedy". Clearly, the two most important tenets of toxicology were established during that time. The level of exposure (dose) and the duration of exposure (time) will determine the degree and nature of a toxicological response.Since that time the discipline of toxicology has made major advances in identifying and characterizing toxicants. The growth of toxicology as a scientific discipline has been driven to a large extent by the use of extremely powerful molecular and cell biology techniques. The overall aim of this volume is to demonstrate how these advances are being used to elucidate causal pathways (or linkages) for potential adverse health consequences of human exposure to environmental chemicals or radiation.A unique feature of this volume is its illustration of how carefully-designed studies of the molecular mechanisms of chemical action provide not only understanding of the potential toxicity of the chemical under investigation, but also new insights into the functioning of the biological system used as an experimental model. Each chapter contains a listing of major peer-reviewed articles and reviews and useful web-sites. In addition, each chapter contains a broad introductory section that outlines the subsequent sections. These Introductory and Overview sections are designed to be stand alone chapters, and may be packaged as a textbook in graduate level courses.

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