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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

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341-350 of 389 results in All results

Adverse Reactions to Drugs

  • 2nd Edition
  • January 1, 1976
  • O. L. Wade + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 1 7 7 - 0
Adverse Reactions to Drugs, Second Edition focuses on the problems posed by the adverse responses to drugs, as well as drug interactions, dosage, and drug metabolism. The publication first tackles adverse reactions and factors which predispose to adverse drug reactions. Topics include dose adjustment, overdose, renal failure, cumulation, side effects, drug allergy, cumulative overdose, and delayed effects. The text then ponders on drug interactions, including renal excretion, drug metabolism, mutual toxicity, and interactions affecting transport to site of action. The manuscript examines adverse reactions in dental practice, drugs used in pregnancy, the neonate, and lactation, and problems for the pharmaceutical industry before marketing a new drug. Discussions focus on ethical problems of drug studies in man, pregnancy, hemorrhage, oxygen toxicity, chloramphenicol, drugs and lactation, drugs used in dental practice, and local anesthetics. The book then elaborates on monitoring adverse reactions to drugs and the therapeutic audit and drug regulatory bodies and their problems. The publication is a valuable source of data for doctors and dentists wanting to focus on research on the adverse reaction to drugs.

Beyond Drugs

  • 1st Edition
  • January 1, 1975
  • Stanley Einstein
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 5 7 4 5 - 0
Beyond Drugs is a 12-chapter book that first presents the critical issues and definitions involved in the study of drug abuse. Subsequent chapters describe the effects of drugs, the drug users, and the contemporary drug culture. Other chapters talk about education, prevention, treatment, and legal control efforts of drug abuse. This book will be useful to those who are generally concerned about drug abuse.

Symposium on Clinical Pharmacology

  • 1st Edition
  • January 1, 1975
  • William A. Creasey + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 3 9 4 0 - 1
Symposium on Clinical Pharmacology reviews advances in clinical pharmacology, with emphasis on how to materially improve the efficacy of cancer chemotherapy. Topics range from absorption, protein binding, distribution, and excretion of antineoplastic drugs to factors affecting the biotransformation and activity of antitumor drugs. The transport of tumor-inhibitory agents across cell membranes is also examined, together with factors influencing drug selectivity and the mechanisms of clinical drug resistance. This volume is comprised of 23 chapters and begins with a brief summary of the different kinds of pharmacokinetic models and how detailed kinetic investigations of a drug in animals may provide further insight into modes of its clinical use. The next chapter considers the chief factors in determining the effective concentration of a drug at a receptor site as well as the duration and intensity of drug effect, citing antineoplastic agents as examples. The role of enzymatic activation and inactivation in drug selectivity is also discussed, along with the general mechanisms of clinical resistance to cancer chemotherapy; biochemical and pharmacological principles of combination chemotherapy; and the reaction and effects of nitrosoureas. This book will be of interest to clinicians, pharmacologists, and biochemists.

Radiation Research

  • 1st Edition
  • January 1, 1975
  • Oddvar F. Nygaard + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 7 0 0 7 - 4
Radiation Research: Biomedical, Chemical and Physical Perspectives documents the proceedings of the Fifth International Congress of Radiation Research held in Seattle, Washington, 14-20 July 1974. While the focus of the Congress was on fundamental research, there were several well-attended sessions on the practical aspects of radiation research as it relates to radiotherapy, central station power generation by both nuclear fission and fusion, and the environment. This volume contains 126 papers organized into 31 parts. Beginning with a keynote address and a lecture on the time scale in radiobiology, the subsequent contributions cover a wide range of topics presented over several sessions. Topics discussed during these sessions include energy needs, nuclear power, and the environment; prospects for fusion power; technological applications of radiation; human radiobiology; hazards of radiation exposure relative to other environmental agents; the basic physics of the interactions of radiation with matter; particle penetration phenomena; and radiation effects in frozen media.

Pesticide Chemistry–3

  • 1st Edition
  • January 1, 1975
  • P. Varo
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 4 7 9 - 8
Pesticide Chemistry—3 provides information pertinent to the fundamental aspects of pesticide chemistry. This book discusses the development of pesticide industry and the progress in pesticide toxicology. Organized into 22 chapters, this book begins with an overview of the important findings with respect to the design of inhibitors of acetylcholinesterase. This text then reviews the statistical, analytical, toxicological, and philosophical role of pesticide residue analysis within the evaluation of environment and food problems. Other chapters consider the factors that influence the persistence of pesticides that are common to both soils and plants. This book discusses as well the insect anti-feeding substances contained in plant leaves, which are widely surveyed by monitoring with leaf-disc test. The final chapter deals with the biological tests necessary for investigating the biochemical and toxicity effects of pesticides to individual species in the plant and animal kingdom. This book is a valuable resource for environmentalists, residue chemists, residue analysts, toxicologists, and official crop protection experts.

Marijuana

  • 1st Edition
  • January 28, 1974
  • Loren L. Miller
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 5 8 1 1 - 9
Marijuana: Effects on Human Behavior attempts to synthesize much of the existing experimentation concerning the acute and chronic effects of marijuana and its derivatives on human behavior. The book opens with a chapter on the strategies for conducting research on marijuana. It also describes a clinical study at the University of British Columbia. The next chapter discusses the issues that have beclouded the question of legalization of marijuana in the United States. This is followed by separate chapters on the effects of marijuana on motor and mental performance; marijuana-memory research; a model of attention which can be used to describe the effects of marijuana use on cognition; and the effects of marijuana on neuropsychological functioning and learning. Subsequent chapters examine the behavioral actions of cannabis in man; compare the behavioral actions of cannabinoids in humans with those found in infrahumans, with special reference to acquisition and retention processes, timing behavior, state-dependent learning, and attention; and investigate the long-term effects of cannabis use.

Progress in Chemical Toxicology

  • 1st Edition
  • January 1, 1974
  • Abraham Stolman
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 1 9 2 4 - 0
Progress in Chemical Toxicology, Volume 5 covers topics on the improved isolation and detection procedures and quantitation methods for volatile poisons, stimulants, hallucinogenic drugs, and marihuana. The book discusses the absorption, distribution, and excretion of drugs and poisons and their metabolites; the system for the toxicological analysis of drugs in biological specimens; and the isolation and analysis of phenothiazines. The text also describes the use of fluorescence in toxicology and the toxicology of new synthetic organic polymers used in containers for food, pharmaceutical compounds, and drinkable water. Some microcrystal tests for drugs and advances in polarography as applied to toxicological analysis are also considered. Biochemists, toxicologists, and scientists involved in the study of narcotics will find the book invaluable.

Blood

  • 1st Edition
  • January 1, 1974
  • Walter S. Root + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 7 2 6 4 - 1
Physiological Pharmacology, Volume V: Blood describes the interrelationships between pharmacology and blood. This volume is organized into five parts encompassing 16 chapters that consider the effect of therapeutic agents on the physiology of blood, whether it be coagulation, the white cells, red cells, or platelets. The opening part deals first with the physiology of blood coagulation and the mode of action of anticoagulants. This part also covers the mechanism of thrombogenesis and thrombolysis, as well as the in vivo actions of thrombolytic agents. The subsequent parts initially examine the biochemistry and physiology of platelets, hematopoietic stem cells, and white cells. These topics are followed by discussions of the mechanism of thrombocytosis and clinical manifestations of thrombocythemia, as well as the mechanisms of immunologic drug effect on blood cells. These parts also explore the effects of drugs on myelopoiesis and the physiological and immunological activities of lymphocytes. The closing part reviews the iron, vitamin B12, folic acid, erythropoietin, and transferrin components of red blood cells. This part also examines the mechanism of erythropoietic cellular proliferation and the initiation of hyperoxia. This book is intended primarily to physiological pharmacologists, hematologists, and researchers.

Forensic Toxicology

  • 1st Edition
  • January 1, 1974
  • Bryan Ballantyne
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 3 3 7 - 4
Forensic Toxicology presents the legal and medical aspects of the detrimental effects of chemicals on humans. This book discusses the immediate and long-term consequences of accident or deliberate poisoning, the detection of such poisoning, and the interpretation of the possible importance of demonstrating exogenous substances in biological fluids and tissues. Organized into 14 chapters, this compilation of papers begins with an overview of the fundamental procedure and interpretation in forensic toxicology. This text then examines the ways in which enzymes may be used in the analysis of drugs. Other chapters consider the equipment and reagents required in the rapid tests for drugs in urine. This book presents as well barbiturate poisoning from the viewpoint of the forensic pathologist performing the post mortem over the cause of death. The final chapter deals with further advances in forensic toxicology. This book is a valuable resource for general practitioners, forensic toxicologists, forensic pathologists, and police officers.

Pyrethrum

  • 1st Edition
  • January 1, 1973
  • John Casida
  • English
  • eBook
    9 7 8 - 0 - 3 2 3 - 1 5 4 9 0 - 1
Pyrethrum: the Natural Insecticide covers the papers presented at the 1972 ""International Symposium on Recent Advances with Pyrethrum the Natural Insecticide"" held in conjunction with the American Institute of Biological Sciences Silver Anniversary Meeting at the University of Minnesota, Minneapolis. It deals with all aspects of pyrethrum, including its history, production, chemistry, biochemistry, toxicology, pharmacology, and agricultural applications. The introductory part addresses the early history of pyrethrum, its recognition as a modern insecticide, and its worldwide production. The chemistry and biochemistry parts discuss the composition, isolation, structure, synthesis, biosynthesis, metabolism, and action on enzyme systems of natural pyrethrins extracted from pyrethrum flower. The book also examines the toxicology of pyrethrum and its constituents to mammals, fish, and wildlife, as well as tests for possible teratogenic, carcinogenic, mutagenic, and allergenic activities. Finally, it discusses the domestic and agricultural applications of pyrethrum. Considering its desirable features, researchers find pyrethrum unsurpassed by any type of synthetic organic insecticide and even by the best synthetic analogs or pyrethroids.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation