ROBOTICS & AUTOMATION
Empowering Progress
Up to 25% off Essentials Robotics and Automation titles
Histopathology of Preclinical Toxicity Studies
Interpretation and Relevance in Drug Safety Evaluation
- 4th Edition - October 7, 2011
- Author: Peter Greaves
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 4 - 5 3 8 5 6 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 4 - 5 3 8 6 1 - 1
The new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the pathology found in drug safety studies in la… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteThe new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. Organized according to organ systems, this revision features a thoroughly updated bibliography and discusses new drug-induced pathologies and applicable species comparisons to aid in the preclinical safety assessment of new medicines. This updated reference is essential for those involved in drug safety evaluation, including pathologists, toxicologists and pharmacologists working in corporate, government, academic and research settings.
- This edition is in full color and features nearly 200 high-quality images
- Provides extended commentary on the relevance of pathological findings and features a fully updated bibliography containing sources for further reading
- Includes new content coverage on the commonly used transgenic animal models that are used in safety assessment, specific tumor types induced by drugs in rodents, and new drug-induced pathologies and lesions
Clinical toxicologists, pathologists, and pharmacologists involved professionally in drug safety evaluation and especially those researchers working in pharmaceutical companies, contract laboratories and in government agencies
Chapter 1. Introduction
References
Chapter 2. Integumentary System
Skin and subcutaneous tissue
References
Chapter 3. Mammary Gland
References
Chapter 4. Hemopoietic and Lymphatic Systems
Blood and bone marrow
Lymphoid system
Lymph nodes
Spleen
Thymus
Lymphoreticular neoplasms
References
Chapter 5. Musculoskeletal System
Bone
Joints
Skeletal muscle
References
Chapter 6. Respiratory Tract
Nose, nasal sinuses, nasopharynx and pharynx
Larynx and trachea
Bronchi and lungs
References
Chapter 7. Cardiovascular System
Heart and pericardium
Systemic blood vessels
Pulmonary blood vessels
References
Chapter 8. Digestive System
Mouth and oropharynx
Salivary glands
Esophagus
Forestomach
Stomach (glandular)
Small intestine
Large intestine
References
Chapter 9. Liver and Pancreas
Liver
Bile ducts, biliary system
Gallbladder
Exocrine pancreas
Endocrine Pancreas
References
Chapter 10. Urinary Tract
Kidney
Urinary bladder
Neoplasia
References
Chapter 11. Male Genital Tract
Prostate gland
Preputial (and clitoral) glands
Epididymis
Testis
References
Chapter 12. Female Genital Tract
Clitoral glands
Vagina
Cervix
Uterus
Ovary
References
Chapter 13. Endocrine Glands
Pituitary gland
Adrenal gland
Thyroid gland
Parathyroid gland
References
Chapter 14. Nervous System and Special Sense Organs
Brain
Spinal cord, spinal nerve roots and peripheral nerves
Eye
Ear
References
Index
- No. of pages: 892
- Language: English
- Edition: 4
- Published: October 7, 2011
- Imprint: Academic Press
- Hardback ISBN: 9780444538567
- eBook ISBN: 9780444538611
PG
Peter Greaves
MBChB, FRCPath, Consulting Pathologist and Honorary Senior Lecturer, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK
Read Histopathology of Preclinical Toxicity Studies on ScienceDirect