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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

    • Pharmacology for Student and Pupil Nurses and Students in Associated Professions

      • 2nd Edition
      • June 6, 2016
      • Bernard R. Jones
      • English
      • Paperback
        9 7 8 0 4 3 3 1 7 5 4 3 8
      • eBook
        9 7 8 1 4 8 3 1 4 1 3 1 2
      Pharmacology for Student and Pupil Nurses and Students in Associated Professions is based on lectures that have been updated and presented to nurses in training for the State Registration and State Enrolment Examinations and to Students in Dispensing. This book describes therapies and drug trends in the industry, as well as many types of drugs, their administration, dosage, usage, and effects. Functions of the pertinent human anatomy are included to illustrate the absorption of these drugs. This book includes a section on patient counseling; the use of the International System of Units (SI); and the immune-response process related to specialized fields of treatment. Patient counseling is undertaken for patients who will continue treatment at home. The nurse gives proper advice on the administration of the patient's medicine. SI was adopted to enhance the standardization of the unit of measurement for volume, weight, temperature, and length. This standard includes the use of the terms Celsius, millimole, and joule and the way of writing abbreviations and numbers in the Metric system. The immune-response process deals with the mechanism and related aspects concerning the two groups of cytotoxics, antimitotics and antimetabolites. The side effects of these drugs when used, for example, in chemotherapy, are discussed. This book will prove useful to pharmacists, student pharmacy technicians, professors of pharmacology, practitioners of general medicines, and specialists with interests in drug therapy.
    • Bacterial Endotoxins

      • 1st Edition
      • June 14, 2016
      • Solomon Kadis + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 4 6 4
      • eBook
        9 7 8 1 4 8 3 2 1 5 8 9 1
      Microbial Toxins, Volume V: Bacterial Endotoxins covers the physiology, pathology, and immunology of bacterial endotoxins. The book discusses the relationship of lipopolysaccharide structure to bacterial virulence; the importance of blood-group and Forssman antigenic determinants in interactions between human and microbes; and the chemical modification of endotoxin and inactivation of its biological properties. The text also describes the effects of endotoxic lipopolysaccharides on the complement system; the host-dependent detoxification of bacterial endotoxin; and the metabolic effects of bacterial endotoxins. The release of vasoactive agents and the vascular effects of endotoxin are also considered. The book further tackles the febrile response to endotoxin; some major aspects and the relationship between shock and endotoxemia; as well as the effects of lipopolysaccharides (endotoxins) on the susceptibility to infections. The text also encompasses the role of hypersensitivity and tolerance in reactions to endotoxins. Pathologists, immunologists, physiologists, and microbiologists will find the book invaluable.
    • Current Concepts in Kinin Research

      • 1st Edition
      • June 6, 2016
      • Gert L. Haberland + 1 more
      • English
      • Hardback
        9 7 8 0 0 8 0 2 3 7 6 1 9
      • eBook
        9 7 8 1 4 8 3 1 5 9 0 9 6
      Current Concepts in Kinin Research contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Paris on July 22, 1978. The book is organized into four parts. Part I explains the functions and mechanisms of the kinin system. Part II focuses on kallikreins and the methods of their determination. Part III describes the intrinsic blood clotting and plasma kinin formation. The last part deals with the characterization of plasma kininogens.
    • Introduction to the Principles of Drug Design

      • 1st Edition
      • June 14, 2016
      • H. J. Smith + 1 more
      • English
      • Paperback
        9 7 8 0 7 2 3 6 0 6 7 2 7
      • eBook
        9 7 8 1 4 8 3 1 8 3 5 0 3
      Introduction to the Principles of Drug Design provides a framework of fundamental drug design and principles into which drugs following on developments may be fitted. This book presents the rationales behind the design of drugs. Organized into nine chapters, this book begins with an overview of how the body handles a drug in terms of absorption, metabolism, distribution, and excretion. This text then examines the critical drug activity at the receptor site, which is usually related to blood and other distribution fluid levels. Other chapters consider the factors involved in binding a drug, metabolite, or substrate to a receptor. The final chapter deals with the design of chemotherapeutic agent for clinical use in the treatment of human infections. This book is intended for use in undergraduate pharmacy courses in medicinal chemistry and as an aid in similar courses in biochemistry and pharmacology. Graduates in chemistry just entering the pharmaceutical industry will also find this book useful.
    • Fungal Toxins

      • 1st Edition
      • June 15, 2016
      • Alex Ciegler + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 4 7 1
      • eBook
        9 7 8 1 4 8 3 2 1 5 9 0 7
      Microbial Toxins, Volume VI: Fungal Toxins covers information on the evaluation of the chemical, biological, and biomedical aspects of the fungal toxins. The book discusses the historical structure chemistry, production, analysis, detoxification, biosynthesis, pharmacology, toxicology, and molecular biochemistry of aflatoxins and related compounds. The text also describes the isolation, analysis, production, chemistry, biological effects, and biogenesis of the ochratoxins, as well as the bioproduction, biosynthesis, and chemical properties of misclellaneous Aspergillus toxins. Various species of storage fungi, including yellowed rice toxins, luteoskyrin and related compounds, chlorine-containing compounds, citrinin, and citreoviridin are also considered. The book further tackles the physical and chemical properties and the biological activity of the rubratoxins; the biosynthesis and biochemical effects of patulin, penicillic acid, and other carcinogenic lactones; as well as the structure, production, biosynthesis, and biological effects of cyclopiazonic acid and related toxins. The text also encompasses bioproduction, properties, chemical structure, and biological activity of miscellaneous Penicillium toxins. Microbiologists, biochemists, epidemiologists, pharmacologists, toxicologists, medical students and people involved in other related fields will find the book useful.
    • Perspectives in Basic and Applied Toxicology

      • 1st Edition
      • October 27, 2016
      • Bryan Ballantyne
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 7 7 2 4
      • eBook
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      Perspectives in Basic and Applied Toxicology features a collection of essays on various aspects of toxicology. It aims to relate fundamental knowledge of toxicology to its application in assessing relevance of that information to the causation of adverse health effects, predicting hazardous situations, defining protective and precautionary measures, and the recognition and management of intoxication in humans. Another objective of this volume is to encourage those with responsibility for the training of toxicologists to instill a greater concern about ethical and moral issues as fundamental to the practice of toxicology as a profession with wide-ranging social implications. This book is organized into 14 chapters. The coverage of these chapters include assessment of chemical hazards in the workplace, the relation between animal studies and epidemiology in the context of industrial toxicology, carcinogenicity testing in animals, and biochemical evaluation of neurotoxicity. This book will be of interest to undergraduate and graduate toxicologists, pharmacologists, physicians, industrial hygienists, and other health professionals.
    • Mustard Lung

      • 1st Edition
      • May 3, 2016
      • Mostafa Ghanei + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 3 9 5 2 6
      • eBook
        9 7 8 0 1 2 8 0 3 9 7 9 3
      Mustard Lung: Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients brings together the details regarding pathophysiology, medication, and protective issues to provide a comprehensive look at health problems associated with sulfur mustard injury. It provides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function. By providing guidelines and approaches for the diagnosis, pathogenesis, and treatment of SM injury cases, this book is helpful for a wide range of medical researchers and clinicians. For decades, chemical respiratory disorders were diagnosed and managed traditionally similar to other chronic respiratory diseases. However, the exact nature of chemical respiratory disorders is different and needs to be treated as such.
    • A Comprehensive Guide to Toxicology in Nonclinical Drug Development

      • 2nd Edition
      • November 3, 2016
      • Ali S. Faqi
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 6 2 0 4
      • eBook
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      A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings.
    • Neurotoxicity of Nanomaterials and Nanomedicine

      • 1st Edition
      • September 28, 2016
      • Xinguo Jiang + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 5 9 8 5
      • eBook
        9 7 8 0 1 2 8 0 4 6 2 0 3
      Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials.
    • Fundamentals of Toxicology

      • 1st Edition
      • August 24, 2016
      • PK Gupta
      • English
      • Paperback
        9 7 8 0 1 2 8 0 5 4 2 6 0
      • eBook
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      Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty.