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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • Essentials of Translational Pediatric Drug Development

      • 1st Edition
      • July 22, 2024
      • Elke Gasthuys + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 8 4 5 9 4
      • eBook
        9 7 8 0 3 2 3 9 0 4 2 9 2
      Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development. The book covers all key aspects from different stakeholder perspectives, providing a literature overview and careful reflection on state-of-the-art approaches. It will be an ideal guide for researchers in the field who are designing and performing high quality, innovative pediatric-adapted drug development by helping them define needs/challenges and possible solutions that advance and harmonize pediatric drug development.Despite the broad consensus that children merit the same quality of drug treatment as any other age group, children remain frequently neglected during drug research and development. Even with the adoption of multiple legislations addressing this problem, the lack of efficacy and safety data of marketed as well as newly developed drugs still remain in the pediatric population.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 63
      • October 4, 2024
      • English
      Progress in Medicinal Chemistry, Volume 63 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this release include Harnessing conformational drivers in drug design, Recent Advances in the Medicinal Chemistry of Heterobifunctional Derivatives for Protein Homeostasis, and A Decade of Antimalarial Drug Discovery: New Targets, Tools and Molecules.

    • Rang y Dale. Farmacología

      • 10th Edition
      • May 15, 2024
      • James M. Ritter + 4 more
      • Spanish
      • Paperback
        9 7 8 8 4 1 3 8 2 6 9 0 5
      • eBook
        9 7 8 8 4 1 3 8 2 7 5 7 5
      Nueva edición del texto clásico en Farmacología y de referencia para los estudiantes de Medicina en el que se aborda de forma exhaustiva, pero clara y organizada el mecanismo de acción de los fármacos más comúnmente usados, tanto a nivel molecular o celular, como de los mecanismos fisiológicos sobre los que actúan.Se ha mantenido la organización general del libro, dividido en 6 grandes secciones en las que se ofrece una descripción de los efectos y usos de los diferentes fármacos junto con su acción sobre las vías de señalización subyacentes a todos los procesos fisiológicos que ocurren en el ser humano. En cuanto a las novedades, si bien todos los capítulos se han actualizado, algunos de ellos han sufrido grandes cambios. Así cabe destacar: Cap 5 (se han incluido un mayor número de fármacos RNA), Cap 24 (recientes avances en la medición de la presión de oxígeno), Cap 40 (se ha puesto el foco en el Alzheimer y la demencia vascular y la asociada a los cuerpos de Levy), Cap 43 (nueva sección destinada al tratamiento del dolor crónico), Cap 51 (nuevos diagramas que ilustran los lugares de acción de los antibióticos a nivel de los ribosomas), Cap 53 (información sobre el modo de replicación de los retrovirales y una sección específica de Covid19) y Cap 57 ( gran y amplia cobertura de los nuevos fármacos anticancerosos). Se ha introducido dos nuevos capítulos. Uno de ellos dedicado a la Farmacología ocular y otro dedicado al tratamiento farmacológico de la migraña en el que se incluyen los nuevos antagonistas de CGRP y su uso profiláctico para la migraña. La nueva edición incluye acceso al e-book en español en el que se incluye contenido adicional (casos clínicos y preguntas de autoevaluación) también en español.

    • TRP Channels as Therapeutic Targets

      • 2nd Edition
      • August 22, 2024
      • Arpad Szallasi
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 6 5 3 0
      • eBook
        9 7 8 0 4 4 3 1 8 6 5 4 7
      TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. Chapters are completely updated, withe new topics on TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. This is a great reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline will also find this book helpful for biologic principles of action.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 62
      • November 17, 2023
      • Jonathan Bentley + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 7 0 3 7
      • eBook
        9 7 8 0 4 4 3 1 3 7 0 4 4
      Progress in Medicinal Chemistry, Volume 62 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors.

    • Privileged Scaffolds in Drug Discovery

      • 1st Edition
      • July 19, 2023
      • Bin Yu + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 6 1 1 0
      • eBook
        9 7 8 0 4 4 3 1 8 6 1 2 7
      Privileged Scaffolds in Drug Discovery is the most complete and up-to-date work in the area. Covering a wide range of privileged structures, it is a perfect reference for scientists involved in targeted drug development.The editors recruited experts from several prestigious Chinese institutions to cover the areas of antiviral drugs, chalcone, pyrimidine, (benz)imidazoles, natural product-derived privileged scaffolds, N-Sulfonyl carboxamides, kinase inhibitors, antitumor molecules, antineurodegenerativ... drugs, triazoles, oxazolidinone, indole and indoline scaffolds, tigliane diterpenoids, peptide and peptide-based drugs, quassinoids, and others including pseudonatural products, macrocycles, stable peptides and peptidomimetics. The book also explores scaffolds in drug molecules approved in recent years.Privileged Scaffolds in Drug Discovery is a complete reference for researchers in drug discovery and organic synthesis, in academic and corporate settings, who are investigating privileged structures upon which to base new drugs. Researchers in medicinal chemistry and chemical biology will also find the contents of this book valuable.

    • Medicinal Chemistry of Anticancer Drugs

      • 3rd Edition
      • April 28, 2023
      • Carmen Avendaño + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 5 4 9 0
      • eBook
        9 7 8 0 1 2 8 1 9 6 5 2 6
      This third edition of Medicinal Chemistry of Anticancer Drugs, provides an updated resource for students and researchers from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. This new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theranostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point of view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature.

    • Recent Developments in Anti-Inflammatory Therapy

      • 1st Edition
      • February 17, 2023
      • Parteek Prasher + 4 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 9 8 8 5
      • eBook
        9 7 8 0 3 2 3 9 1 4 1 6 1
      Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation.

    • Pulmonary Pharmacology

      • 1st Edition
      • Volume 98
      • August 1, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 8 8 0 0
      • eBook
        9 7 8 0 4 4 3 1 8 8 8 1 7
      Pulmonary Pharmacology, Volume 98 provides in-depth reviews on the latest progresses about respiratory drug discovery and development. Topics covered in this volume include corticosteroids, monoclonal antibodies, tyrosine kinase inhibitors and phosphodiesterase inhibitors for the treatments of asthma, COPD or pulmonary fibrosis, with perspective on the development of novel therapeutic strategies such as renin-angiotensin system modulators, mitochondrial function modulators, and non-antibacterial macrolides. Part of the volume is devoted to senotherapy for lung ageing in respiratory diseases, and novel pulmonary delivery technologies, including inhaled biologics.

    • New Approaches Towards Novel Antibacterial Agents

      • 1st Edition
      • Volume 60
      • October 27, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 7 1 1 2
      • eBook
        9 7 8 0 4 4 3 1 3 7 1 2 9
      New Approaches Towards Novel Antibacterial Agents, Volume 60 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

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