Brody's Human Pharmacology
- 7th Edition - January 31, 2024
- Editors: Lynn Wecker, Susan L. Ingram
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 4 6 7 3 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 4 6 7 4 - 5
Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both… Read more
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Request a sales quoteBrody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives.
What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.
- Contains all the essential aspects of pharmacology – suitable for exam preparation
- Full color illustrations explain important processes and color-coded boxes enhance understanding
- Therapeutic overviews, clinical problems and trade names – everything you need to know
- Self-assessment questions and further reading to reinforce learning
- Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life
- Cover image
- Title page
- Table of Contents
- Any screen, Any time, Anywhere
- Copyright
- Contributors
- Preface
- Dedication and Acknowledgments
- Section 1: Mechanisms of Drug Action and Therapeutic Principles
- 1. Introduction
- Website
- 2. Cellular Receptors and Drug Concentration–Response Relationships
- Abstract
- Biological Sites and Specificity of Drug Action
- General Properties of Cellular Receptors
- Agonists and Antagonists
- Receptor Families, Subtypes, and Signaling Cascades
- Quantitative Relationships
- Self-Assessment Questions
- Website
- 3. Pharmacokinetics
- Abstract
- Absorption and Distribution
- Metabolism and Elimination of Drugs
- Clinical Considerations
- Calculation of Pharmacokinetic Parameters
- Multiple or Prolonged Dosing
- Pharmacogenomics
- Special Populations and Disease Considerations
- Biologics
- Summary
- Self-Assessment Questions
- Further Reading
- 4. Pharmacogenetics
- Abstract
- Genes Affecting Pharmacokinetics: Drug Metabolism and Drug Transporters
- Genes Affecting Pharmacodynamics
- Cancer Pharmacogenetics
- Summary
- Self-Assessment Questions
- Further Reading
- Websites
- 5. Drug Discovery, Development, and Regulation
- Abstract
- Introduction
- Drug Discovery and Development
- Prescription Writing and Regulation
- Summary
- Terms
- Self-Assessment Questions
- Further Reading
- Websites
- Section 2: Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses
- 6. Introduction to the Autonomic Nervous System
- Abstract
- Divisions of the Autonomic Nervous System
- Control of the Autonomic Nervous System
- Functional Responses Mediated by the Autonomic Nervous System
- Neurotransmission in the Autonomic Nervous System
- Neurotransmitters in the Autonomic Nervous System
- Neurotransmitter Receptors in the Autonomic Nervous System
- Drugs Affecting the Autonomic Nervous System
- New Developments
- Self-Assessment Questions
- Further Reading
- Websites
- Cholinergic Drugs
- 7. Muscarinic Agonists, Cholinesterase Inhibitors, and Their Clinical Uses
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 8. Muscarinic Antagonists and Their Clinical Uses
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 9. Nicotinic Agonists and Their Clinical Uses
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- Clinical Relevance for Healthcare Professionals
- New Developments
- Self-Assessment Questions
- Further Reading
- Website
- 10. Neuromuscular Blocking Drugs and Nicotinic Antagonists
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- Adrenergic Drugs
- 11. Adrenergic Agonists and Their Clinical Uses
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 12. Adrenergic Antagonists and Their Clinical Uses
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Mixed-Action β1-Adrenergic Receptor Antagonist and β3-Adrenergic Receptor Agonist
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Section 3: Drug Treatment for Disorders Affecting the Central Nervous System
- 13. The Central Nervous System
- Abstract
- Introduction
- Neurotransmission in the Central Nervous System
- Organization of the Central Nervous System
- Drug Action in the Central Nervous System
- Self-Assessment Questions
- Further Reading
- Website
- 14. Drug Therapy for Alzheimer Disease and Other Cognitive Disorders/Dementias
- Abstract
- Therapeutic Overview
- Pathophysiology
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 15. Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 16. Drug Therapy for Psychoses and Bipolar Disorder
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 17. Drug Therapy for Depression and Anxiety
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 18. Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- Drug Use Disorder and Dependence
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 19. Drug Therapy for Insomnia and the Hypersomnias
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 20. Drug Therapy for Managing Obesity and Eating Disorders
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 21. Treatment of Seizure Disorders
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 22. Drug Therapy for Spasticity Disorders
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 23. Ethanol, Other Alcohols, and Medications for Alcohol Use Disorder
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 24. Psychoactive Compounds and Substance Use Disorder
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Section 4: Drug Therapy for Pain Management
- 25. Introduction
- Abstract
- Neurophysiology of Pain
- Specific Pain Syndromes
- Further Reading
- Website
- 26. General Anesthetics
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 27. Local Anesthetics
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Practitioners
- Self-Assessment Questions
- Further Reading
- Websites
- 28. Opioid Analgesics
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 29. Nonsteroidal Antiinflammatory Drugs and Acetaminophen
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 30. Cannabinoids
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 31. Drug Therapy for Migraine Headache
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Section 5: Treatment of Inflammatory, Allergic and Immunologic Disorders
- 32. Drug Therapy for Gout and Hyperuricemia
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 33. Pharmacological Interventions for Allergic Reactions
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 34. Immunosuppressants for Autoimmune Disorders and Organ Transplantation
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 35. Drug Therapy for Rheumatoid Arthritis
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Section 6: Drug Treatment for Cardiovascular Diseases
- 36. Introduction to the Regulation of Cardiovascular Function
- Abstract
- Central Control of Autonomic Nerve Activity
- Regulation of Sympathetic Activity
- Further Reading
- Self-Assessment Questions
- Websites
- 37. Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- 38. Diuretics and Drugs That Affect Volume and Electrolyte Content
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 39. Drugs Affecting the Renin-Angiotensin-Aldosterone System
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 40. Calcium-Channel Blockers
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 41. Vasodilators for Hypertensive Crises, Pulmonary Hypertension, and Erectile Dysfunction
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 42. Treatment of Hyperlipidemias and Atherosclerotic Cardiovascular Disease
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 43. Treatment of Myocardial Ischemia and Angina Pectoris
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 44. Treatment of Heart Failure
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 45. Antiarrhythmic Drugs
- Abstract
- Therapeutic Overview
- Cardiac Electrophysiology
- Mechanisms of Action of Antiarrhythmic Drugs
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 46. Anticoagulant, Antiplatelet, and Fibrinolytic Medications
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 47. Drug Therapy for Hemophilia and the Deficiency Anemias
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Section 7: Treatment of Endocrine Disorders
- 48. Introduction to Endocrine Pharmacology
- Abstract
- Introduction
- Hormones
- New Developments
- Clinical Relevance for Healthcare Professionals
- 49. Treatment of Hypothalamic and Pituitary Disorders
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 50. Diagnosis and Treatment of Adrenocorticosteroid Disorders
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 51. Female Hormone Regulation
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 52. Androgens, Antiandrogens, and Their Clinical Uses
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 53. Drug Therapy for the Management of Diabetes
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 54. Drug Therapy for the Management of Thyroid Disorders
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 55. Calcium Regulating Hormones and Other Agents Affecting Bone
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Section 8: Chemotherapy
- Infectious Diseases
- 56. Principles of Antimicrobial Use
- Abstract
- Introduction
- Drug-Bacteria Interactions
- Host-Bacteria Interactions
- Drug-Host Interactions
- Antimicrobial Therapy
- Self-Assessment Questions
- Further Reading
- Websites
- 57. Drugs Targeting Bacterial Cell Walls and Membranes
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 58. Drugs Targeting Bacterial Protein Synthesis
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 59. Drugs Targeting Bacterial DNA
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 60. Antimycobacterial Agents
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 61. Drugs Targeting Resistant Organisms
- Abstract
- Therapeutic Overview
- Multidrug-Resistant Gram-Positive Bacteria
- Multidrug-Resistant Gram-Negative Bacteria
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Parasitic Diseases
- 62. Antifungal Agents
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Website
- 63. Antimalarial and Other Antiprotozoal Agents
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 64. Anthelmintics and Ectoparasiticides
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Viruses
- 65. Antiviral Agents
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 66. Antiretroviral Drugs for HIV
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Cancer
- 67. Principles of Cancer and Antineoplastic Drug Use
- Abstract
- Overview
- Cancer in the Clinic
- Biology of Cancer
- Treatment of Cancer
- Common Problems in the Treatment of Cancer
- New Developments
- Self-Assessment Questions
- Further Reading
- Websites
- 68. Cytotoxic Agents
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 69. Targeted Anticancer Agents
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 70. Immunological and Cell-Based Therapies
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Section 9: Special Considerations
- 71. Therapeutic Use of Hematopoietic Growth Factors
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 72. Gastrointestinal Disorders and Their Treatment
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 73. Pharmacological Interventions for Asthma and Chronic Obstructive Pulmonary Disorders
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 74. Dietary Supplements, Nutraceuticals, and Natural Products
- Abstract
- Therapeutic Overview
- Mechanisms of Action
- Pharmacokinetics
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacovigilance: Side Effects, Clinical Problems, and Toxicity
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 75. Essentials of Toxicology
- Abstract
- Toxicology Overview
- Mechanisms of Action
- Toxicant Interactions
- Emerging Issues
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- 76. Therapeutic Considerations for Pregnant, Pediatric, Geriatric, and Obese Individuals
- Abstract
- Therapeutic Overview
- Relationship of Population Characteristics to Drug Responses
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Further Reading
- Websites
- Appendix
- Answers to Self-Assessment Questions
- Index
- Confidence is ClinicalKey
- No. of pages: 800
- Language: English
- Edition: 7
- Published: January 31, 2024
- Imprint: Elsevier
- Paperback ISBN: 9780323846738
- eBook ISBN: 9780323846745
LW
Lynn Wecker
Professor Lynn Wecker has recently retired from teaching at USF College of Medicine Tampa Florida, and has agreed to stay on for a final edition to help Susan learn the ropes.
Affiliations and expertise
Distinguished University Professor, Departments of Psychiatry and Behavioral Medicine and Molecular Pharmacology and Physiology, Director, Laboratory of Neuropsychopharmacology, USF College of Medicine, Tampa, FloridaSI
Susan L. Ingram
Professor Susan Ingram is a Professor of Neurological Surgery at Oregon University, she is a contributor on the 6th edition and has worked with Lynn on various projects over the years.
Affiliations and expertise
Professor of Neurological Surgery, School of Medicine, Oregon Health & Science University, Portland, Oregon