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Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Sciences collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

  • Multifunctional Nano pharmaceuticals for Biomedical Applications

    • 1st Edition
    • Sushil K. Kashaw + 3 more
    • English
    Multifunctional Nanopharmaceuticals for Biomedical Applications is an essential resource for researchers interested in the transformative potential of nanotechnology in drug delivery and disease treatment. This comprehensive guide not only covers the latest advancements in multifunctional nanopharmaceuticals, but also addresses the pressing need for innovative solutions for unmet medical challenges. With the rapid evolution of nanomedicine, this book serves as a crucial tool for researchers, students, healthcare professionals, and industry experts alike, bridging the gap between fundamental concepts and their real-world applications.The contents of the book are organized into three parts: Foundations and Platforms, Advanced Platforms and Emerging Technologies, and Clinical Considerations and Future Perspectives. Each chapter explore key topics such as the fundamentals of nanotechnology and drug delivery, PEGylated lipid carriers for cancer theranostics, and the latest in biomimetic nanomicells and nanorobots. With detailed discussions on design strategies, formulation techniques, and regulatory aspects, readers will gain a thorough understanding of the complexities and innovations in this dynamic field. The exploration of clinical applications and future trends equips readers with the knowledge to navigate the evolving landscape of nanomedicine.Multifu... Nanopharmaceuticals for Biomedical Applications empowers readers to harness cutting-edge technologies for effective therapies, paving the way for a new era of personalized, precise, and potent medicine. Corporate researchers in pharma will benefit from the multiple case-studies developed by authors, showing the application of nanotechnology in healthcare.

  • Pharmaceutical QbD with Design of Experiments

    Statistical Tools and Applications in Drug Delivery Systems
    • 1st Edition
    • Khushwant Yadav
    • English
    Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

  • Artificial Intelligence in Precision Drug Design, Volume 2

    Advanced Applications
    • 1st Edition
    • Khalid Raza
    • English
    Artificial Intelligence in Precision Drug Design, Volume 2: Advanced Applications explores the transformative role of AI in modern drug discovery and development, presenting cutting-edge research and methodologies that integrate machine learning, network pharmacology, and computational modeling to accelerate therapeutic innovation. It covers a wide range of applications, including AI-driven drug repurposing, combination therapies, cancer immunotherapy, neuroscience, vaccine development, and molecular dynamics, but also delves into emerging technologies such as quantum computing, large language models, and graph neural networks. Designed for academics, this volume provides researchers, clinicians, and graduate students with a resource on the latest AI methodologies in precision medicine.Users will find this to be a great resource that supports evidence-based innovation, fosters interdisciplinary collaboration, and equips them with insights to advance personalized healthcare solutions.

  • Protein-Based Nanoparticles in Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Protein-based Nanoparticles in Drug Delivery is a comprehensive book aimed at pharmaceutical scientists and researchers both in academia and corporate environments focused on nanotechnology drug delivery and pharmaceutical-relat... disciplines. The book covers the design and characterization of various protein nanoparticles, sheds light on the power of an endogenous substance as a drug delivery system, and highlights the possible future trends in the use of protein-based drug delivery. It covers in-depth novel applications of protein-based drug delivery from fundamental to most current use cases. The book comprises three parts. Part one is devoted to the foundations of protein-based drug delivery, including nanocarriers development, drug encapsulation, targetability, and in vivo properties. Part two explores the applications of protein-based nanoparticles in drug delivery, covering topics such as protein nanoparticles in cancer therapy, genetic material delivery, and nanocarriers based on milk protein, silk, and gliadin. Part three addresses recent advances and regulatory aspects of protein-based nanoparticles in drug delivery, including clinical translation, challenges, biological toxicity, and environmental hazards associated with protein-based nanoparticles. Protein-based Nanoparticles in Drug Delivery provides a complete journey of protein-based drug delivery, offers an in-depth understanding of the design and characterization of various protein nanoparticles, and highlights possible future trends in this field. Pharmaceutical scientists will benefit from the novel applications of protein-based nanoparticles drug delivery approaches in the biological field. Nanotechnologists, biologists, chemists, physicists, engineers, and clinicians will also benefit from the foundational content provided as a basis to support communication and tackle the multidisciplinary challenges associated with research in this exciting field.

  • Artificial Intelligence in Precision Drug Design, Volume 1

    Foundations and Core Techniques
    • 1st Edition
    • Khalid Raza
    • English
    Artificial Intelligence in Precision Drug Design, Volume One: Foundations and Core Techniques offers a comprehensive introduction to the transformative role of AI in modern drug discovery. The book lays the groundwork for understanding how machine learning, deep learning, and generative models are reshaping the development of precision therapeutics. It explores foundational topics such as AI-driven molecular screening, pharmacokinetics, ADMET modeling, toxicity prediction, and omics integration. In addition, sections address ethical, philosophical, and epistemological dimensions, ensuring a well-rounded perspective. Each chapter, authored by global experts, combines theoretical insights with real-world case studies to bridge the gap between AI and life sciences.Designed for graduate students, researchers, and professionals in bioinformatics, biomedical sciences, and pharmaceutical R&D, this volume equips readers with essential knowledge and tools to navigate the evolving landscape of AI in drug design. It empowers interdisciplinary learners to apply cutting-edge AI techniques to real-world biomedical challenges.

  • Advances in Tablet Manufacturing Technologies

    • 1st Edition
    • Honey Goel + 2 more
    • English
    Advances in Tablet Manufacturing Technologies consolidates cutting-edge information on the latest technologies in tablet design and manufacturing, addressing the pressing need for innovation in an increasingly complex global market. The book is structured to provide a thorough understanding of tablet technology, beginning with foundational concepts and progressing through specialized topics. Key sections explore the historical context of tablet development, the significance of pharmaceutical excipients, preformulation aspects, and the physics of tablet compression. Subsequent chapters explore advanced topics, including coated tablets, modified-release formulations, organ-specific tablets, and state-of-the-art innovations like 3D printed tablets.Each chapter is enriched with practical examples and case studies, ensuring that readers can apply theoretical knowledge to real-world scenarios. With contributions from a diverse group of national and international experts, this book is an invaluable asset for scientists in academia and industry alike. It elucidates preformulation parameters, outlines regulatory frameworks, and discusses recent advances in excipient technology and in-process testing equipment.

  • Developing Solid Oral Dosage Forms

    Pharmaceutical Theory and Practice
    • 3rd Edition
    • Yihong Qiu + 4 more
    • English
    Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Third Edition is a comprehensive and up-to-date guide for professionals and academics engaged in all aspects of oral dosage form development, from discovery support through commercial manufacturing. This new edition features 13 new or rewritten chapters, along with significant updates to existing content, reflecting the latest advancements in the field, including new theories, scientific findings, approaches, techniques, modeling, and the emerging opportunities offered by AI.This book consists of 44 chapters covering in-depth principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their applications throughout the R&D process and commercial production of oral dosage forms. New chapters address topics such as absorption evaluation of oral dosage forms, formulation principles, and applications based on supersaturation, patient-centric product design, product design through the 505(b)(2) NDA pathway, design of experiments (DoE), process modeling, 3D printing, and machine learning applications in commercial manufacturing. Existing chapters have been updated or completely rewritten to provide advanced information and include practical case studies. Important topics such as amorphous solid dispersions, modified-release delivery, manufacturing technologies, modeling and simulation, fundamentals of dissolution and bioequivalence, IVIVC, biowaivers, regulatory frameworks, and many others are covered.The new edition of this book is an indispensable resource for industry professionals, academic institutions, and regulatory bodies seeking to stay current with advances in solid dosage form development and manufacturing. It offers a thorough understanding of fundamental principles and techniques, along with practical guidance on applying these concepts to real-world challenges.

  • AI Powered Drug delivery to Neuro and Cardiovascular Systems

    Perspectives and Future Challenges
    • 1st Edition
    • Chandra P. Sharma + 2 more
    • English
    AI-Powered Drug Delivery to Neuro and Cardiovascular Systems: Perspectives and Future Challenges is a definitive reference exploring the transformative influence of Artificial Intelligence (AI) in neuro and cardiovascular drug delivery. This book integrates cutting-edge research to explain how AI is poised to reshape clinical protocols, therapeutic strategies, and regulatory standards. By examining advancements in robotics and intelligent systems, it demonstrates how AI enhances precision, personalization, and efficiency in drug delivery for heart and neurological conditions, providing readers with a thorough understanding of these innovations and their potential to revolutionize healthcare practices.The book delves into AI-driven drug design and testing for cardiovascular diseases and explores the application of AI in cardiac drug delivery vehicles. It discusses bioengineered heart and vessel therapeutics, redox homeostasis, and targeted drug replenishment in cardiac matrix remodeling. Additionally, it addresses mitochondrial drug retention, AI-assisted gene therapy for neurodegenerative disorders, and the role of AI in optimizing heart health. The text highlights smart systems for managing cerebrovascular accidents and neuromodulation with pharmacotherapy. Finally, it covers translational challenges, future directions, and the significance of AI-driven prediction models and robotic delivery mechanisms.

  • Fundamentals of Biologicals Regulation

    Vaccines and Biotechnology Medicines
    • 2nd Edition
    • Rebecca Sheets + 6 more
    • English
    Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines, Second Edition serves as an introduction to the international regulatory arena in which biologicals are developed, offering an overview of processes and insights into the scientific concepts underpinning global regulations. This edition provides in-depth coverage of Quality by Design, Combination Products, Risk Management Plans, REMS, and switching from reliance on in vivo to in vitro analytical methods. It reflects new developments and processes accelerated by the COVID-19 vaccine experience, including emergency use authorizations and conditional marking authorizations. New pedagogic elements and case studies have been added to improve learning outcomes.This book provides multiple levels of readership, with guidance on basic concepts, a detailed look at regulatory challenges, and practical insights into how regulators consider regulatory science and regulatory process issues across various regions, with an emphasis on the European Medicines Agency and the U.S. Food and Drug Administration.

  • Basic Principles of Drug Discovery and Development

    • 3rd Edition
    • Benjamin E. Blass
    • English
    Basic Principles of Drug Discovery and Development, Third Edition presents a unique overview of the drug discovery and development program not available elsewhere. Each chapter provides sufficient technical details on the topics covered so that non-experts will have the tools and information necessary to interact and exchange information with colleagues across the entire spectrum of the drug discovery and development process. The drug discovery and development process involves individuals and teams with a wide array of expertise ranging from basic sciences (medicinal chemistry, biology) to applied science (pharmacology, pharmacokinetics, clinical sciences) to business driven fields (regulatory affairs, intellectual property experts, marketing specialists).The success or failure of a program focused on bringing a new medication to market often depends on clear communication between individuals and teams with vastly different expertise. As a result, it is critical that experts in one aspect of drug discovery and development (e.g., medicinal chemists) have a working understanding of the wide range of disciplines that take part in the overall process.

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