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Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

BooksJournals

    • Channelopathies

      • 1st Edition
      • November 16, 2000
      • F. Lehmann-Horn + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 4 8 9 0
      • Paperback
        9 7 8 0 4 4 4 5 4 5 0 5 3
      • eBook
        9 7 8 0 0 8 0 5 2 8 8 5 4
      This book describes human hereditary ion channel diseases of voltage- and ligand-gated ion channels covering the diverse fields of medicine myology, neurology, cardiology, and nephrology requiring a wide and interdisciplinary readership. Interesting parallels in pathogenetic mechanisms of disease are especially emphasized to interest even highly specialized readers in entities outside of their fields. Each author has written an objective overview of his or her particular subject in a way that should allow the reader within a short period of time to obtain a comprehensive picture of the present state of art.

    • Volume Transmission Revisited

      • 1st Edition
      • Volume 125
      • November 7, 2000
      • L.F. Agnati + 3 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 3 1 4 5
      • eBook
        9 7 8 0 0 8 0 9 2 9 2 9 3
      Volume Transmission Revisited describes the mounting evidence that cells of the central nervous system are able to communicate via a host of chemical signals that flow through the extracellular space. Volume transmission (VT) constitutes a novel and complementary communication system to classical synaptic transmission. The new modality, which does not require specific connections between cells, leads to a reconsideration of the spatial relationships of neurons and glia, brings a new dimension to network modelling and is relevant to both short term interactions and long term tonic states of the brain.The reader will find 29 chapters describing many of the major discoveries in VT during the last decade.The most striking feature of this publication is the collecting together of many compelling examples of the ubiquitous nature of VT. These point to its increasing relevance from basic neuroscience research to clinical practice. Those working in other areas will find numerous invaluable examples of how leading investigators have gone about assembling evidence for VT.

    • Glutamate

      • 1st Edition
      • Volume 18
      • November 3, 2000
      • J. Storm-Mathisen + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 3 9 5 7 1
      • eBook
        9 7 8 0 0 8 0 5 3 2 5 7 8
      The volume presents a comprehensive and up-to-date treatise of the glutamatergic synapse and its environment. Particular emphasis is on the localizations of the molecular constituents of the synaptic machinery. Immunogold and other high-resolution methods are used extensively. Each chapter presents new data that have not previously been reviewed. The material presented forms the basis for work directed to understanding the functional properties of excitatory synapses in greater depth, to discover mechanisms of neurological and psychiatric disorders and novel methods for treatment. Chapter 1 deals with the transmitter molecule itself, mechanisms of release and pathways for glutamate synthesis. The anatomy of glutamatergic nerve projection pathways in different brain regions is dealt with. In Chapter 2, focus is on aspartate, the enigmatic congener of glutamate, and its possible role in excitatory neurotransmission. Chapters 3 through 6 deal with glutamate receptors. Metabotropic glutamate receptors are presented in Chapter 3. Chapter 4 presents an in situ hybridization atlas of the different classes of ionotropic glutamate receptors. The localizations of these receptors at the regional and synaptic level are presented in Chapter 5. The ways in which the receptors are brought to the synapse and held in position are the subject of Chapter 6. Chapter 7 deals with the enzymes responsible for formation and catabolism of glutamate. In Chapter 8, the regulation of extracellular glutamate levels by glutamate transporters is discussed. The final two chapters of the volume focus on two "model synapses" that, due to special features, lend themselves particularly well to demonstrating properties of glutamatergic synapses. The hair cell-to-afferent nerve terminal synapses in the inner ear (Chapter 9), with their supporting cells, share essential properties with glutamatergic synapses in the central nervous system. The salient features of the latter are illustrated by the synapses of the giant reticulo-spinal axons of the lamprey, used to unravel molecular mechanisms of the cycling of synaptic vesicles (Chapter 10).

    • Neural Plasticity and Regeneration

      • 1st Edition
      • Volume 128
      • October 26, 2000
      • F.J. Seil
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 2 0 9 4
      • eBook
        9 7 8 0 0 8 0 9 2 9 2 3 1
      While a cure for spinal cord injury remains elusive, the contents of this volume convey a sense of progress towards this goal. More has been learned about the primary and secondary consequences of spinal cord injury and more is being understood about recovery mechanisms that are intrinsic to the nervous system and that might be further encouraged. Expanding the control capacity of uninjured portions of the nervous system may be one approach to improving the functional capabilities of those afflicted with this disorder. New therapies in the form of transplantable cells that can encourage growth or myelination or prevent secondary damage or that can substitute for injured cells appear promising for future applications. Genetic and tissue engineering studies give us further hope, and under continuous development are novel drugs with greater specificity and fewer detrimental effects and improved delivery methods for such drugs. The volume is organized into six topic sections, including I) Strategies for Spinal Cord Injury Repair, II) Plasticity of the Injured Spinal Cord: Retraining Neural Circuits to Promote Motor Recovery, III) Impact of Neuroprosthetic Applications on Functional Recovery, IV) Neurotrophins and Activity-Dependent Plasticity, V) Candidate Cells for Transplantation into the Injured CNS and VI) New Directions in Regeneration Research. Both clinical and experimental animal studies are presented in the first three sections, while predominantly basic research is the focus of the second half of the book.

    • Psychology of Learning and Motivation

      • 1st Edition
      • Volume 40
      • October 19, 2000
      • English
      • Hardback
        9 7 8 0 1 2 5 4 3 3 4 0 2
      • eBook
        9 7 8 0 0 8 0 5 2 2 7 3 9
      The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter provides a thoughtful integration of a body of work. Volume 40 includes in its coverage chapters on memory, categorization, implicit and explicit learning, and the effects of rewards and punishments on learning.

    • MRI Atlas of the Human Cerebellum

      • 1st Edition
      • August 16, 2000
      • Jeremy D. Schmahmann + 4 more
      • English
      • eBook
        9 7 8 0 0 8 0 5 7 4 0 7 3
      The MRI Atlas of the Human Cerebellum constitutes the most complete, detailed work on the human cerebellum to date. This definitive work provides images in the three cardinal planes (sagittal, transverse, and coronal) at closely spaced intervals of 2 millimeters. The images are derived from MRI scans of one individual and from postmortem sections of another. It is the only such atlas set within the universally accepted framework of the Talairach stereotaxic system, derived from standard landmarks in the brain. The book includes a new nomenclature system (labeling system) which is easier to use, aids in understanding the organization of the cerebellum, and is consistent with earlier work on the anatomy of the cerebellum in animals and the development of the human cerebellum in infants.Recent studies have shown that the cerebellum is involved in much more than motor coordination alone: also in higher functions including memory, language, emotion, and attention, as well as sensory discrimination. This atlas facilitates this new era of study of the cerebellum, allowing investigators to identify cerebellar structures with precision. Everyone concerned with the anatomy, function, or dysfunction of the cerebellum should have a copy.

    • Neurobiology of Addiction

      • 1st Edition
      • July 21, 2000
      • George F. Koob + 1 more
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature.

    • Computational Neuroscience

      • 1st Edition
      • July 8, 2000
      • J.M. Bower
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 5 4 9 1
      • eBook
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      This volume includes papers originally presented at the 8th annual Computational Neuroscience meeting (CNS'99) held in July of 1999 in Pittsburgh, Pennsylvania. The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as experimental preparations and theoretical approaches. The papers published here range across vast levels of scale from cellular mechanisms to cognitive brain studies. The subjects of the research include many different preparations from invertebrates to humans.In all cases the work described in this volume is focused on understanding how nervous systems compute. The research described includes subjects like neural coding and neuronal dendrites and reflects a trend towards forging links between cognitive research and neurobiology. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.

    • Functional Neuroanatomy of the Nitric Oxide System

      • 1st Edition
      • Volume 17
      • June 30, 2000
      • H.W.M. Steinbusch + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 3 5 5 4
      • Hardback
        9 7 8 0 4 4 4 5 0 2 8 5 8
      • eBook
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      This volume of the Handbook of Neuroanatomy is concerned with nitric oxide synthase. In this volume different research areas are presented together, which adds up to the first major review volume on the localization of nitric oxide synthase in the nervous system. The subjects range from developmental aspects in vertebrates to a functional neuroanatomy of the nervous system in vertebrates. This presentation gives an impressive look on the overwhelming presence of NOS in animal organism and the significance of NO - cGMP signaling. By clearly stating the limitations of our present knowledge the book is also a stimulant for further research. This book presents for the first time an overview of NOS and NO-cGMP signaling in the retina and urogenital system. In addition the effects if injuries on the expression of NOS are summarized in a number of models, which has not been done before.The frame of the book is a classical neuroanatomic description of the localization of NOS. Several authors give detailed advice to prevent pitfalls which may occur when different methods to locate NOS are used. In addition, several chapters detail the target structures for NO while describing the localization of NOS at the same time.All these points together make this volume very timely, i.e. overviewing a decade of NO research.

    • Peptide Receptors, Part I

      • 1st Edition
      • Volume 16
      • June 8, 2000
      • A. Bjorklund + 2 more
      • English
      • Hardback
        9 7 8 0 4 4 4 8 2 9 7 2 6
      • eBook
        9 7 8 0 0 8 0 5 3 8 5 8 7
      During the last few years, the pace of research in the field of neuropeptide receptors has increased steadily: new neuropeptides were discovered, and the classification of receptor subtypes has been refined. It thus appeared essential to update the information. Peptide Receptors Part I summarizes current knowledge on ten distinct peptide families.This volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry, and immunocytochemistry images. Application of these classical techniques and of new approaches such as transgenic and knock-out animals has revealed a distinct species and tissue specific variation in receptor subtypes expression and pharmacology in the mammalian central nervous system.The functional role of neuropeptides and their receptors in the CNS has been investigated thanks to the development of potent and selective receptor antagonists and agonists. The development of specific neuropeptide-related molecules will help to get a better understanding of receptor subtype physiology and neuronal distribution and may lead to innovative treatments in a variety of brain disorders.

Related subjects

Behavioral neuroscience

Cognitive neuroscience

Developmental neuroscience and regeneration

Molecular neuroscience

Neural aging

Neuroanatomy

Neurobiology

Neurochemistry

Neuroendocrinology

Neurogenetics

Neuroimmunology

Neurology

Neuropathology

Neuropharmacology

Neurophysiology

Neuroscience general

Neuroscience methodology

Neurotoxicology

Sensory systems