Skip to main content
Elsevier
View Cart

Books in Neurology

BooksJournals

    • Tinnitus: Pathophysiology and Treatment

      • 1st Edition
      • Volume 166
      • October 31, 2007
      • Aage R. Moller + 4 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 3 1 6 7 4
      • eBook
        9 7 8 0 0 8 0 5 5 4 4 6 4
      Understanding tinnitus and treating patients with tinnitus must involve many disciplines of basic science and clinical practice. The book provides comprehensive coverage of a wide range of topics related to tinnitus including its pathophysiology, etiology and treatment. The chapters are written by researchers and clinicians who are active in the areas of basic science such as neurophysiology and neuroanatomy and in clinical specialties of psychology, psychiatry, audiology and otolaryngology.

    • Neuro-inflammation in Neuronal Death and Repair

      • 1st Edition
      • Volume 82
      • July 25, 2007
      • Stuart Lipton + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 3 9 8 9 6
      • eBook
        9 7 8 0 0 8 0 5 5 0 5 6 5
      Neuroinflammation has been implicated recently in the pathogenesis of many neurodegenerative diseases. The cross-talk between neurons and non-neuronal cells seems to be a critical step in the progression of neurodegeneration and molecules that have a beneficial role may turn into harmful players. Thus, matrix metalloproteinases (MMPs), which are involved in axonal growth and regeneration as well as synaptic plasticity, may also have detrimental effects. Recent evidence has linked MMPs to conditions like ischemia, multiple sclerosis, Alzheimer's disease and suggested that, together with their role in the degradation of extracellular macromolecules, MMPs could work as important signalling molecules from injured neurons to the microglia. Thus, MMP-3 has been shown to induce the release of pro-inflammatory cytokines from microglia via activation of ERK and NF-kB-dependent pathways. Increasing evidence highlights the importance of a balanced cross-talk between neurons and non-neuronal cells and indicates that the presence of reactive astrocytes, the activation of microglia and the release of inflammatory mediators may contribute to the progression of many central nervous system disorders, independently of the nature of the primary pathogenic event. However, many aspects still remain controversial and much more effort is needed to understand the role of neuroinflammatory mediators and processes in these conditions. This volume brings together renowned, international scientists to discuss current knowledge and views on the mechanisms of neuroinflammation, on its role in the context of different neurodegenerative diseases (i.e. Alzheimer's, prion disease, HIV-associated dementia, multiple sclerosis, pain) and on the potential approaches for future therapeutic strategies.

    • Molecular Neurology

      • 1st Edition
      • July 17, 2007
      • Stephen Waxman
      • English
      • Hardback
        9 7 8 0 1 2 3 6 9 5 0 9 3
      • eBook
        9 7 8 0 0 8 0 5 4 6 1 8 6
      Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology.

    • Myopathies and Muscle Diseases

      • 1st Edition
      • Volume 86
      • July 16, 2007
      • Frank L. Mastaglia + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 8 9 9 6
      • eBook
        9 7 8 0 7 0 2 0 3 5 3 7 1
      This volume provides a comprehensive guide to myopathies, including breakthroughs that have led to a wider appreciation of the nature of these muscle diseases. Chapters on congenital muscle disorders, biological changes, and diseases associated with aging are included, along with detailed discussions of mitochondrial myopathies, disorders of carbohydrate and lipid metabolism, and the role of heredity, amongst others. Neurologists, myopathologists, and other professionals dealing with this broad group of diseases will find state-of-the-art information on the clinical investigation and management of patient care, as well as the latest information on the pathological basis and molecular pathogenesis of these diseases.

    • HIV/AIDS and the Nervous System

      • 1st Edition
      • Volume 85
      • July 16, 2007
      • Peter Portegies + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 2 0 1 0 4
      • Paperback
        9 7 8 0 4 4 4 5 2 9 0 4 6
      • eBook
        9 7 8 0 7 0 2 0 3 5 3 6 4
      This volume provides a comprehensive understanding of HIV/AIDS and neuro-AIDS, including a history of the disease, and an explanation of many of the conditions that can arise in afflicted patients, including opportunistic infections, central nervous system tumors, spinal cord disorders, myopathies and progressive encephalopathy, amongst others. Clinicians will gain a greater understanding of the complex mechanisms of the disease. Beginning with a basic introduction to HIV infections and Neuro-AIDS, practitioners will find useful data on advances in molecular biology, neuroepidemiology, neuroimaging, neuropathology, neuropharmacology, as well as information on the development of therapeutic strategies appropriate for the disorder, including groundbreaking retroviral therapies. In addition, the socioeconomic and political constraints that hinder treatment and disease management in developing parts of the world are presented.

    • Trisomie et handicaps génétiques associés

      • 5th Edition
      • June 22, 2007
      • French
      • eBook
        9 7 8 2 9 9 4 0 9 8 0 2 7
      Destiné aux professionnels de santé médicaux et paramédicaux, cet ouvrage aborde de manière concrète et pragmatique tous les aspects de la prise en charge d'un patient atteint de trisomie ou d'un handicap génétique associé. Avec une symptomatologie actualisée, un suivi médical étape par étape et des conseils validés, le lecteur trouvera ici un outil indispensable et à jour pour le suivi de son patient et pour apporter toute l'aide nécessaire à la famille. L'auteur a particulièrement développé dans ce nouvel ouvrage tous les aspects pratiques de l'aide à apporter aux patients atteints de trisomies pour améliorer leur qualité de vie ainsi que des réponses précises aux questions que se posent les parents tout au long des étapes de vie de l'enfant et de la personne concernée (prise en charge précoce, scolarisation, développement affectif et sexuel, activités sportives, relations avec les adolescents et la fratrie, formation professionnelle, loisirs, tabac, alcool, liberté de déplacement, permis de conduire, relation avec l'argent, protection juridique, revenus, habitat, vie en couple, contraception, vieillissement …). En réponse à une forte demande, cet ouvrage, 5e édition totalement renouvelée, étudie notamment la prise en charge des oro praxies, le vieillissement et introduit la notion nouvelle de « périodes phares ou charnières » qui déterminent l'avenir du patient atteint de trisomie.

    • Neurobiology of Epilepsy and Aging

      • 1st Edition
      • Volume 81
      • April 16, 2007
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 2 7 8 0
      • Hardback
        9 7 8 0 1 2 3 7 4 0 1 8 2
      • eBook
        9 7 8 0 0 8 0 4 8 9 2 5 4
      This volume in the International Review of Neurobiology series addresses the epidemiology, pathophysiology, and treatment of epilepsy in elderly patients. Demographically, the elderly comprise both the fastest-growing segment of the U.S. population and the adult age group with the highest incidence of epilepsy, yet there are relatively few publications devoted to this clinical subgroup. The intersection of these two complex processes—epilepsy and advancing age—will have an increasing impact on medical and community care. The etiology, prognosis, and differential diagnosis of epilepsy can all be affected by the normal aging process and by the frequent comorbidities encountered in an elderly population. Chapters in this book review the effects of aging on brain function and on drug metabolism and interactions, covering the gamut of research from animal models of aging and epilepsy to clinical trials and outcomes. Topics also include the dangers of misdiagnosing status epilepticus, the special issues encountered in recruiting and retaining elderly clinical trial participants, and the use of antiepileptic drugs in the elderly. In both the clinic and the research laboratory, a better understanding of how epilepsy may differ between younger and older patients will be valuable in determining the best possible care for geriatric patients with epilepsy.

    • Eye Movements

      • 1st Edition
      • March 27, 2007
      • Roger PG van Gompel
      • English
      • Hardback
        9 7 8 0 0 8 0 4 4 9 8 0 7
      • eBook
        9 7 8 0 0 8 0 4 7 4 9 1 5
      Eye-movement recording has become the method of choice in a wide variety of disciplines investigating how the mind and brain work. This volume brings together recent, high-quality eye-movement research from many different disciplines and, in doing so, presents a comprehensive overview of the state-of-the-art in eye-movement research. Sections include the history of eye-movement research, physiological and clinical studies of eye movements, transsaccadic integration, computational modelling of eye movements, reading, spoken language processing, attention and scene perception, and eye-movements in natural environments.

    • Integrating the Neurobiology of Schizophrenia

      • 1st Edition
      • Volume 78
      • February 27, 2007
      • English
      • Hardback
        9 7 8 0 1 2 3 7 3 7 3 7 3
      • Paperback
        9 7 8 0 3 2 3 2 8 3 6 4 9
      • eBook
        9 7 8 0 0 8 0 4 7 5 0 8 0
      This book examines the role that dopamine plays in schizophrenia, examining its role in not only the symptoms of the disease but also in its treatment. It also reviews all neurotransmitters that have been implicated in schizophrenia, exploring the genetic data, clinical data implicating the transmitter, and the preclinical data exploring how a transmitter may interact with dopamine and contribute to the dopaminergic phenotype observed in the illness. This book will serve as an educational tool for instructors, a guide for clinicians, and be of interest to researchers. It is a good reference for researchers specialized in one particular area and interested in learning about other areas of pathology in schizophrenia and how they may all feed into each other. The book concludes with an overall integrative model assembling as many of these elements as possible.

    • Manuel d'EEG de l'adulte

      • 1st Edition
      • February 20, 2007
      • Chantal Hausser-Hauw
      • French
      • Paperback
        9 7 8 2 2 9 4 0 7 1 4 5 4
      • Paperback
        9 7 8 2 2 9 4 7 3 3 7 4 1
      • eBook
        9 7 8 2 9 9 4 1 0 0 6 0 7
      Quelle est la place, aujourd’hui, de l’électroencéphalogr... ? Non invasif et peu coûteux, l’EEG rend compte de l’activité électrique cérébrale du patient à l’instant même où elle est enregistrée et apporte une analyse immédiate du fonctionnement correct du cerveau ou de son atteinte. Sa place dans l’étude du sommeil est primordiale. L’EEG nécessite un minimum de compréhension des principes physiques et des techniques d’enregistrement des rythmes cérébraux et du sommeil. Cet ouvrage a été conçu chapitre par chapitre pour familiariser le lecteur à l’intérêt de l’EEG dans le diagnostic des épilepsies, des complications neurologiques des maladies systémiques, des encéphalopathies, de l’éthylisme, de la grossesse et des effets médicamenteux, des traumatismes crâniens en phase aiguë et chronique. Le rôle médico-légal de l'EEG dans l’anoxie et la mort cérébrale et son aide dans le diagnostic des démences sont également détaillés. L’étude du sommeil des maladies dégénératives est particulièrement développée. Les maladies pour lesquelles l’EEG offre un supplément d’information par rapport à l’imagerie en cas de crises épileptiques, de confusion ou de troubles de la vigilance sont exposées. Une partie est consacrée à l’intérêt de l’EEG en psychiatrie. Enfin, l’ouvrage détaille l’usage de l’EEG lors d’événements transitoires comme la migraine, l’ictus amnésique, la plongée, la privation sensorielle et lors des états volontairement modifiés de la conscience (biofeedback, méditation, hypnose).

Related subjects

Autonomic nervous system

Clinical neuropathology

Clinical neurophysiology

Epilepsy

Neuro ophthalmology

Neuroimaging

Neurological research

Pediatric neurology