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Books in Neurology

  • Neuromuscular Junction Disorders

    • 1st Edition
    • Volume 91
    • A. G. Engel
    • English
    This volume provides concise and comprehensive information on neuromuscular disorders, including rapid advancements in the understanding of the neurobiology of neuromuscular transmission. In addition, clinicians will find timely discussions on the various forms of these disorders that have been discovered due to increased study within the field. New observations into the immunopathogenesis of myasthenia gravis, and the molecular mechanisms underlying the links between activity and patterns of gene expression, particularly in muscle, are also explored, along with novel information on the understanding of the pathophysiology of the heterogeneous group of peripheral nerve hyperexcitability syndromes. Each of these valuable insights, and their accompanying explanations, provides a framework on which new therapeutic strategies can be built to aid in the enhancement and restoration of normal function in neuromuscular junction disorders.

  • Psychiatric Controversies in Epilepsy

    • 1st Edition
    • Andres Kanner + 1 more
    • English
    Psychiatric Controversies in Epilepsy addresses controversial clinical issues of the psychiatric aspects of epilepsy. The book explores the reasons behind the poor communication between psychiatrists and neurologists and suggests potential remedies to this important problem, and two chapters are devoted to examining whether psychiatrists and neurologists are properly trained to recognize and treat conditions that both disciplines commonly encounter in clinical practice. Identification of the causes behind the high rate of comorbidity between epilepsy and mood, anxiety, psychotic and attention deficit disorders is given high priority in the volume, and a specific review of the evidence of common pathogenic mechanisms that may be operant in epilepsy and these psychiatric disorders is included. Recently identified bidirectional relationship between mood disorders and epilepsy and its implication in the course and response to treatment of the seizure disorder are also explored. Several chapters are devoted to rectify common misunderstandings of the use of psychotropic drugs in patients with epilepsy, including the use of antidepressant and central nervous system stimulants. Finally, one chapter explores the possibility of organic causes of psychogenic non-epileptic seizures.

  • Dementias

    • 1st Edition
    • Volume 89
    • Charles Duyckaerts + 1 more
    • English
    This volume provides a comprehensive understanding of the biology of dementias, including information on advancements in the way these disorders are perceived and studied. From earlier assumptions that cognitive deficits were simply age related, this handbook progresses into complex discussions of the diseases that affect the cortex of the human brain. Clinicians will find extensive diagnostic and research perspectives on a variety of interesting topics, including neuropathology, physiopathology, biology, clinics, and imaging information on all, or most, of the dementing disorders currently known. In addition, chapters devoted to legal and ethical issues give practitioners and health care workers an informative view on complex dementias and the way these disorders affect patients and families. Clinicians in all levels of expertise will find useful and synthetic information.

  • Disorders of Consciousness

    • 1st Edition
    • Volume 90
    • G. Bryan Young + 1 more
    • English
    This volume encompasses a variety of topics pertaining to patients with altered levels of consciousness, including valuable differences between disorders. Neurologists, researchers, and clinicians will find a comprehensive accounting of the distinctions between disorders that cause these altered states. Beginning with basic concepts of consciousness and neurobiology, this handbook progresses into more targeted and complex areas of discussion, including important technological advancements that have occurred in neuroimaging. Neurologists who are frequently called upon for prognostication and to guide management of patients with these disorders will find invaluable information, including chapters discussing comatose states in children and pregnant women, encephalopathic patients, nutrition disorders, and vegetative and minimally conscious states. In addition, chapters devoted to philosophical backgrounds and ethical implications involving patients with impaired consciousness, are thoroughly presented.

  • Neurologie du comportement

    La dimension neurologique de la neuropsychologie
    • 1st Edition
    • Armin Schnider
    • French
    À la confluence de la neurologie, de la neuropsychologie et de la psychiatrie, la neurologie comportementale est une spécialité qui s'intéresse aux troubles cognitifs, émotionnels et comportementaux dus à des atteintes cérébrales. Elle explore les mécanismes, la base anatomique et les étiologies des dysfonctionnements des fonctions supérieures du cerveau, telles que la mémoire, le langage, la pensée spatiale et le raisonnement. Conçu dans une approche clinique, cet ouvrage constitue une introduction approfondie à la neurologie du comportement. Après un rappel des bases anatomiques du cerveau, chaque chapitre traite successivement des principaux troubles : • État confusionnel et troubles de l'attention • Syndromes frontaux • Aphasies et syndromes apparentés • Troubles du traitement spatial • Agnosies • Troubles mnésiques • Syndromes calleux • Démences Ces troubles sont d'abord définis, puis passés au crible de l'analyse anatomoclinique afin d'en examiner les causes et l'évolution. Pour chacune de ces pathologies, les techniques d'évaluation sont détaillées en fonction du contexte clinique. Aussi, cet ouvrage présente un réel intérêt pratique et pédagogique à travers l'étude de nombreux cas cliniques, des propositions de tests adaptés, et de multiples schémas anatomiques et tableaux récapitulatifs.

  • Neuropsychology and Behavioral Neurology

    • 1st Edition
    • Volume 88
    • Georg Goldenberg + 1 more
    • English
    This volume presents a comprehensive guide to one of the most important goals of neuroscience, establishing precision structure-function relationships in the brain. Progressing from the early stages of research, specifically the advent of computerized tomography and later, magnetic resonance imaging, this invaluable resource will take clinicians on an all encompassing journey into the ways different fields of neurology can work together to advance our understanding of brain disorders. Complex topics including the neurochemistry of cognition, neuropsychology of aging and dementia, disorders of semantic memory, working memory, and the dysexecutive syndromes, amongst others, are thoroughly discussed and presented. Clinicians will find a state-of-the-art reference guide that can be used to further understand how the fields of neuropsychology and behavioral neurology can complement each other to produce advancements in the neurosciences.

  • Computational Neuroscience in Epilepsy

    • 1st Edition
    • Ivan Soltesz + 1 more
    • English
    Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering.

  • Fundamental Neuroscience

    • 3rd Edition
    • Larry Squire + 6 more
    • English
    Fundamental Neuroscience, Third Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts.Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers!

  • CNS Regeneration

    Basic Science and Clinical Advances
    • 2nd Edition
    • Jeffrey Kordower + 1 more
    • English
    This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury.

  • Metabolic Syndrome and Psychiatric Illness: Interactions, Pathophysiology, Assessment and Treatment

    • 1st Edition
    • Scott D Mendelson
    • English
    Metabolic syndrome is a set of risk factors that includes: abdominal obesity, a decreased ability to process glucose (insulin resistance), dyslipidemia (unhealthy lipid levels), and hypertension. Patients who have this syndrome have been shown to be at an increased risk of developing cardiovascular disease and/or type 2 diabetes. Metabolic syndrome is a common condition that goes by many names (dysmetabolic syndrome, syndrome X, insulin resistance syndrome, obesity syndrome, and Reaven's syndrome). This is the first book to fully explain the relationships between psychiatric illness, Metabolic Syndrome, diet, sleep, exercise, medications, and lifestyle choices. Metabolic Syndrome is a major risk factor in Major Depression, Alzheimer's Disease, Sleep Disorders, Sexual Dysfunction, Fibromyalgia, and several other illnesses of psychiatric significance. Conversely, some psychiatric illnesses tend to predispose patients to Metabolic Syndrome. Of further interest is the fact that some of the medications used in the treatment of psychiatric illnesses have been found to cause or exacerbate Metabolic Syndrome. The author here provides basic information about what genetic predispositions, medical conditions, and lifestyle choices make Metabolic Syndrome more likely to occur. Among the contributing factors that are discussed are genetics, habitual intake of high glycemic index carbohydrates, fructose, saturated fats, trans fatty acids, vitamins, micronutrients, obesity, smoking, and lack of exercise. The author describes the actual mechanisms by which Metabolic Syndrome progresses and causes damage in the body, including the action of insulin and the pathophysiology of insulin resistance. Details are provided on what occurs in the liver, pancreas, muscle, fat cells, and immune system as Metabolic Syndrome progresses. New findings are presented on fat cells, including the fact that they are beginning to be considered as endocrine cells. There is a substantive discussion of leptin, which is one of the important adipocytokines. Also carbohydrate, 'bad fats', inflammation, oxidative damage, over-stimulation of the 'fight or flight' system, and high levels of the stress hormone cortisol can actually cause the manifestations of Metabolic Syndrome. These explanations set the stage for an explanation of the inter-relationships between Metabolic Syndrome, psychiatric illness, dementia and effects of not only diet and life choices, but also the effects of psychiatric medications. Finally, there is an important and unique section on the relationship between Metabolic Syndrome and various psychiatric illnesses, and how they exacerbate each other. The significance of Metabolic Syndrome in Major Depression, Bipolar Affective Disorder, Schizophrenia, fibromyalgia and Polycystic Ovary Disease is vast and it is important to realise the effects of psychiatric medications on Metabolic Syndrome. The author discusses antidepressants, mood stabilizers and the new atypical antipsychotics. There are dramatic differences among medications in the way they affect Metabolic Syndrome and pharmaceutical companies will want to promote patient awareness with this book.

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