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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Extracellular Vesicles from Basic Research to Clinical Applications

      • 1st Edition
      • Volume 94
      • October 5, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 4 9 6 9
      • eBook
        9 7 8 0 4 4 3 2 9 4 9 7 6
      Extracellular Vesicles from Basic Research to Clinical Applications, Volume 94 covers theses lipid bilayer particles containing proteins, glycoproteins, mRNA, other small RNA species, and lipids formed and released by various pathogens. Chapters in this update include Extracellular Vesicles release from protozoa parasite and animal model, EVs from parasite and biomarkers, Translational Medicine – Use of EVs as therapy, EVs and viruses and their interaction with cells, EVs and Toxoplasma gondii, EVs and Fungi, Biogenesis of EVs in parasites, Extracellular vesicles, EVs and Leishmania, EVs in neuropsychiatry, EVs and Bacteria.Other sections cover EVs and sleep deprivation, EVs and cancer, Extracellular vesicles and methods to isolation, purification, and characterization.
    • Molecular Biology of B Cells

      • 3rd Edition
      • January 10, 2024
      • Tasuku Honjo + 4 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 5 8 9 5 0
      • eBook
        9 7 8 0 3 2 3 9 5 8 9 6 7
      Molecular Biology of B Cells, Third Edition provides a comprehensive reference on how B cells are generated, selected, activated, and engaged in antibody production. These developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. The book offers an integrated view of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. This new edition provides updated research on B cell development and function, the use of therapeutic antibodies in cancer and infectious disease, and more. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, this updated release is a definitive resource, vital for researchers across molecular biology, immunology, and genetics.
    • Atlas of Hematopathology with 100 Case Studies

      • 1st Edition
      • June 3, 2024
      • Faramarz Naeim + 2 more
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 8 3 8 1
      • eBook
        9 7 8 0 4 4 3 1 8 8 3 9 8
      Atlas of Hematopathology with 100 Case Studies is a practical guide useful for pathologists and hematologists, residents and fellows, laboratory directors, researchers, and students in the field of hematology, cytogenetic, and molecular pathology. The book offers important information to practicing physicians and those in pathology and hematology training to improve their diagnostic skills. It covers the most important aspects of hematopathology, including classifications, clinical symptoms, hematopathologic features, diagnostic criteria, differential diagnosis, and the use and importance of ancillary testing, such as immunohistochemistry... flow cytometry, and cytogenetics.
    • RNA Therapeutics Part B

      • 1st Edition
      • Volume 204
      • March 6, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 5 4 4 3
      • eBook
        9 7 8 0 4 4 3 2 3 5 4 5 0
      RNA Therapeutics, Part B, Volume 204 updates on a new class of medication based on RNA molecules, with chapters on a variety of topics, including RNA therapeutics for cardiovascular disorders, RNA therapeutics for kidney injury, RNA therapeutics for beta-thalassemia, RNA therapeutics for infectious diseases, RNA therapeutics for reproductive diseases, Potential of RNA and transcriptomic data to drive drug repurposing for various diseases, RNA therapeutics for glioma/glioblastoma, RNA therapeutics for regenerative medicine, Advances in the liposome-based delivery systems for RNA therapeutics in cancer, Advances in the polymeric nanoparticulate delivery systems for RNA therapeutics in cancer, and more.
    • Translational Bioinformatics

      • 1st Edition
      • Volume 139
      • March 6, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 1 9 3 4 8 4
      • eBook
        9 7 8 0 4 4 3 1 9 3 4 9 1
      Translational Bioinformatics is an emerging field in the direction of biomedical research. High throughput technologies can be applied to the generated biological data to develop the vaccine and personalized medicine. This volume consists of the chapters from different stalwart of the field covering the topics such as drug development, vector engineering, vaccine development and translational genomics. Chapters covered in this volume discuss the translational research related with cancer, Alzheimer disease and cardiovascular diseases. This volume includes the chapter describing the importance of computational resources and chemoinformatics for the translational health research. How Omics studies are helping to translate the laboratory data into the development of tools which are beneficial in the clinics have been described. How translational bioinformatics helpful in plant genomics to improve the crops have also been included in this volume. This volume has a chapter which describes the secrets of resistance development and further how these resistance are associated with human infectious diseases. This volume will be useful to the early career researcher in the development of research idea and develop their methodologies in the direction of bioinformatics and it will also give the insight to translate their findings.
    • Chemokine Receptors in Health and Disease

      • 1st Edition
      • Volume 388
      • September 10, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 2 1 7 2 9
      • eBook
        9 7 8 0 4 4 3 2 2 1 7 3 6
      This volume reviews the current research in Chemokine Receptors and their role in physiological processes in the body, as well as their role in different pathological conditions. Chemokine Receptors are important for the migration of different types of cells, including immune cells to lymphoid organs and non-lymphoid organs thanks to the interaction with chemokines. The presence of different chemokine receptors on the cells’ surface was studied in normal states and diseases, some of them correlating with migration of subsets that play pro-disease roles or other help controlling the condition. Currently, state-of-the-art technology is helping researchers to better identify gene and protein expression of chemokine receptors at the single cell level. This large new data reveals the complexity of co-expression of various markers in the same cells and as well among different types of cells. Moreover, chemokine receptors are also helpful to identify different stages among subsets, and their correlation with better or worst responses in disease. Finally, treatments designed to inhibit or to block chemokine receptors are designed and tested at the preclinical and clinical level with different results. Here, we focus on the main chemokine receptors described in the current literature that play a role in health and diseases such as infections, autoimmune disorders, and cancer.
    • Clinical Application of Repurposed Drugs

      • 1st Edition
      • Volume 207
      • June 28, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 4 1 1 4 7
      • eBook
        9 7 8 0 4 4 3 2 4 1 1 5 4
      Clinical Application of Repurposed Drugs, Volume 207 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Drug repurposing for viral disease, Drug repurposing for bacterial infections, Drug repurposing for parasitic protozoan diseases, Drug repurposing for fungal infections, Drug repurposing for treating anxiety and depression, Drug repurposing for personalized medicine, Drug repurposing for cancer, Drug Repurposing: A multi targeted approach to treat cardiac disease from existing classical drugs to modern drug discovery, and much more.Additional chapters cover Drug repurposing in MASLD and MASH-cirrhosis: targets and treatment approaches based on pathways analysis, Drug repurposing for respiratory infections, Drug repurposing for rare disease, Drug repurposing for neurological disorders, Drug repurposing for metabolic disorders: scientific, technological and economic issues, Drug repurposing for regenerative medicine and cosmetics: scientific, technological and economic issues, and Exploring Cutting-Edge Omics-Driven Strategies for Drug Repurposing – An Insight into the Tools of the Trade.
    • Advances in Marine Biology

      • 1st Edition
      • Volume 97
      • September 20, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 7 4 6 5
      • eBook
        9 7 8 0 4 4 3 2 9 7 4 7 2
      Advances in Marine Biology, Volume 97, the latest release in this serial that highlights new advances in the field, including comprehensive chapters written by an international board of authors.
    • Myeloid-Derived Suppressor Cells

      • 1st Edition
      • Volume 184
      • March 19, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 8 0 7 1
      • eBook
        9 7 8 0 4 4 3 2 1 8 0 8 8
      Myeloid-Derived Suppressor Cells, Volume 184 in the Methods in Cell Biology series includes comprehensive protocols to assess the role of myeloid-derived suppressor cells (MDSCs), an immature, heterogenous cell population from the myeloid lineage with a potent immunosuppressive activity in a variety of diseases. This volume includes interesting protocols that address the Detection of myeloid-derived suppressor cells by flow cytometry, Determination of murine myeloid-derived suppressor cells by flow cytometry, Isolation of Myeloid-Derived Suppressor Cells (MDSC) from Endometriotic Mice Model and their Immunomodulatory Functions, Simple protocol for measuring CD11b+ GR-1+ (Ly6C+/Ly6G+) myeloid cells from a minimum volume of mouse peripheral blood, and much more.Additional chapters cover Assessment of myeloid-derived suppressor cell differentiation ex vivo, Single clonal tracking on biomimetic microtextured platforms for real-time guided migration analysis of myeloid-derived suppressor cell dissemination characteristics ex vivo, Isolation and immunosuppressive functions of myeloid-derived suppressor cell-derived exosomes, Characterization of lysosomal acid lipase in Ly6G+ and CD11c+ myeloid-derived suppressor cells, In Vitro Osteoclastogenesis Assessment using Murine Myeloid-derived Suppressor Cells, Estimating Nitric Oxide (NO) from MDSCs by Griess Method, and In vitro generation of myeloid-derived suppressor cells (MDSCs) from hematopoietic progenitor cells (HPCs).
    • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

      • 7th Edition
      • November 14, 2024
      • Reed E. Pyeritz + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 2 5 3 1 1
      • eBook
        9 7 8 0 1 2 8 1 2 6 7 9 0
      **Selected for 2025 Doody’s Core Titles® in Clinical Genetics**For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world’s most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the seventh edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, and genetic counseling. Volumes 3–11 cover diagnosis, management, and treatment of both rare and common disorders in all organ systems. Students, medical providers, and researchers all benefit from the latest information about the role of the genome in health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals across the full spectrum of applications to medicine.In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to endocrine, skin, connective tissue and skeletal disorders, with emphasis on understanding the genetic mechanisms underlying these conditions, diagnostic approaches, and treatment methods that make use of current genomic technologies and translational studies.With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics, seventh edition, bridges the gap between high-level molecular genetics and genomics and practical application and serves as an invaluable clinical tool for the health professionals and researchers.