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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Mononuclear Non-heme Iron Dependent Enzymes Part B

      • 1st Edition
      • Volume 704
      • September 17, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 3 4 6 4 7 7
      • eBook
        9 7 8 0 4 4 3 3 4 6 4 8 4
      Mononuclear Non-heme Iron Dependent Enzymes, Volume 704, Part B focuses on methods for studying, characterizing, and leveraging the chemistry of mononuclear non-heme iron dependent enzymes. Chapters in this new release include Observing extradiol dioxygenases in action through a crystalline lens, Methods used to determine the structure of the oxygenase component of naphthalene 1,2-dioxygenase, Expression, purification, kinetics, and crystallization of non-heme mononuclear iron enzymes: biphenyl, phthalate, terephthalate dioxygenase, Substitution of the Mononuclear, Non-heme Iron Cofactor in Lipoxygenases for Structural Studies: Non-heme iron enzyme dependent reactions, and much more.Other sections cover Cyclopropanation and aziridination catalyzed by non-heme iron and 2-oxogluatarate dependent enzymes, Expression, purification, and characterization of non-heme Iron-dependent mono-oxygenase OzmD in Oxazinomycin Biosynthesis, Isonitrile Biosynthesis by a Non-Heme Iron(II)-Dependent Oxidases/Decarboxyla... Functional analysis of an a-ketoglutarate-depe... non-heme iron oxygenase in fungal meroterpenoid biosynthesis, Spectroscopic and Computational Studies of a Bifunctional Iron- and 2-oxoglutarate Dependent Enzyme, AsqJ, and much more.

    • Non-Traumatic Acute Surgical Problems

      • 1st Edition
      • September 16, 2024
      • Constantine P. Spanos
      • English
      • Paperback
        9 7 8 0 4 4 3 3 3 8 3 3 5
      • eBook
        9 7 8 0 4 4 3 3 3 8 3 4 2
      Non-Traumatic Acute Surgical Problems: An Infographic Guide is curated to offer a comprehensive understanding of acute surgical challenges, excluding trauma. Tailored specifically for medical students navigating their surgical rotations and seasoned instructors in the field, this guide serves as an indispensable resource. Each chapter serves as a path through the intricacies of acute surgical conditions with clarity and depth. Contents provide insight into the complexities of acute cholecystopathy, appendicitis, and acute pancreatitis, providing invaluable insights into diagnosis and sophisticated management strategies. This book navigates through the labyrinth of gastrointestinal bleeding scenarios, encompassing upper, lower, and variceal bleeding, as well as formidable challenges like caustic ingestion and esophageal perforation. Contents further cover vascular emergencies, unraveling the mysteries of aortic dissection, peripheral arterial embolism, and hypercoagulability, while mastering essential principles for timely and effective intervention. Coverage includes the subtleties of urological emergencies such as renal colic, pyelonephritis, and testicular torsion, alongside gynecological conditions including ectopic pregnancy and pelvic inflammatory disease.With a wealth of information, thoughtfully structured in an accessible format, this book not only empowers but emboldens its readers. Equipped with knowledge, insight, and confidence, individuals traversing the realm of acute surgical problems are fortified to navigate the challenges of real-world clinical settings with unwavering competence and assurance.

    • Childhood Obesity

      • 1st Edition
      • September 13, 2024
      • Luis Moreno
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 9 7 5 7
      • eBook
        9 7 8 0 4 4 3 2 1 9 7 4 0
      Childhood Obesity: From Basic Knowledge to Effective Prevention brings together field experts, taking a multifactorial approach to understand the scope and various causes of the issue and offer the latest in treatment and prevention strategies and resources. Beginning with basic concepts and definitions, chapters progress to cover worldwide prevalence and trends, genetic and epigenetic origins, metabolic programming, and neuroendocrine control of appetite and satiety. Further, this book examines social determinants and lifestyle behaviors contributing to risk factors as well as complications associated with childhood obesity.Final chapters discuss multidisciplinary treatment, strategies for prevention, and current worldwide policies aimed to address obesity in children. This fundamental reference is a vital resource for both researchers and practicing clinicians in pediatric medicine.

    • Cutting Edge Artificial Intelligence, Spatial Transcriptomics and Proteomics Approaches to Analyze Cancer

      • 1st Edition
      • Volume 163
      • September 12, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 6 5 0 5
      • eBook
        9 7 8 0 4 4 3 2 9 6 5 1 2
      Cutting Edge Artificial Intelligence, Spatial Transcriptomics and Proteomics Approaches to Analyze Cancer, Volume 163 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting topics on the Impact of thermal processing on food flavonoids, Bioinformatics and bioactive peptides from foods: does it work together?, Food off-flavor volatiles generation, characterization and advances in novel strategies for mitigating off-flavor perception, Innovations in Food Packaging for a Sustainable and Circular economy, Upcycling of seafood side streams for circularity, Edible insects in foods, Effect of novel food processing technologies on Bacillus cereus spores, and more.

    • CRISPR-Cas-Based Genome Editing for Treating Human Diseases-Part A

      • 1st Edition
      • Volume 208
      • September 11, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 5 8 8 6
      • eBook
        9 7 8 0 4 4 3 3 1 5 8 9 3
      CRISPR-Cas-Based Genome Editing for Treating Human Diseases-Part A, Volume 208 represents CRISPR-Cas systems for genome editing. Currently, CRISPR-Cas systems are proven a key technology for targeted genome editing, which is acting as a simple, rapid, and cost-effective solution. CRISPR-Cas9 system is being used in microbial genome editing, mammalian genome editing, disease models, and more. It has shown potential in human disease treatment. However, it is not easy to find CRISPR-Cas systems genome editing in a single source.This volume offers CRISPR-Cas systems for human diseases, bacterial disease, gut microbiome editing, viral disease, protozoan disease, fungal disease, stem cell therapy, CRISPR in epigenetics, CRISPR in cancer, autoimmune and blood disorders. In addition, it highlights a number of aspects of the CRISPR-Cas systems that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

    • Fundamentals of Recombinant Protein Production, Purification and Characterization

      • 1st Edition
      • September 10, 2024
      • Deepti Yadav + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 8 3 8 8 4
      • eBook
        9 7 8 0 3 2 3 9 8 5 8 4 0
      Fundamentals of Recombinant Protein Production, Purification and Characterization is organized into nine chapters in a logical fashion that cover an introduction to recombinant proteins and expression in different host expression systems, extraction, purification and analysis of proteins. This important reference features protocols, along with the advantages and disadvantage of each expression hosts and characterization technique (presented in tabular format) and offers detailed coverage of all aspects of protein production and processing (upstream and downstream processing) in one place. Finally, the book ends with different characterization techniques. Production of recombinant proteins for biotechnological and therapeutic applications at a large scale is an essential need of mankind. With the huge application potential of therapeutic and industrial proteins, there has been increasing demand for effective and efficient bioprocessing strategies. Recent progress around recombinant DNA technologies and bioprocessing strategies has paved the way for efficient production of recombinant proteins. Important factors such as insolubility and cost of production need to be considered for large scale production of these recombinant proteins.

    • Myopathies and Tendinopathies of the Diabetic Foot

      • 1st Edition
      • September 10, 2024
      • Claude Pierre-Jerome
      • English
      • Hardback
        9 7 8 0 4 4 3 3 3 9 7 7 6
      • eBook
        9 7 8 0 4 4 3 1 3 3 2 9 9
      Myopathies and Tendinopathies of the Diabetic Foot: Anatomy, Pathomechanics, and Imaging is a unique reference of valuable instructive data that reinforces the understanding of myopathies and tendinopathies related to diabetes-induced Charcot foot. Diabetic myopathies usually precede other complications (i.e., deformity, ulceration, infection) seen in the diabetic foot. Oftentimes, these myopathies may be isolated especially during their initial stage. In the absence of clinical information relevant to diabetes, the solitaire occurrence of myopathies may lead to confusion, misinterpretation, and misdiagnosis. The misdiagnosis can cause delay of management and consequent high morbidity. This book emphasizes the complications of diabetic myopathies and tendinopathies and all their aspects, including pathophysiology, pathomechanics, imaging protocols, radiological manifestations, histological characteristics, and surgical management.Diabetes type II and its complications (diabetic myopathies and tendinopathies) have reached a dreadful high incidence worldwide. Likewise, the need for better understanding of these complications becomes indispensable. In this book, the readers of all genres will find all they need to know about these conditions. This book serves as a classic academic reference for educators, healthcare specialists, healthcare givers, and healthcare students.

    • Mononuclear Non-heme Iron Dependent Enzymes

      • 1st Edition
      • Volume 703
      • September 10, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 3 0 4 2
      • eBook
        9 7 8 0 4 4 3 3 1 3 0 5 9
      Mononuclear Non-heme Iron Dependent Enzymes, Volume 703 focuses on methods for studying, characterizing, and leveraging the chemistry of mononuclear non-heme iron dependent enzymes. Chapters in this new release include Photoreduction for Rieske oxygenase chemistry, Insights into the Mechanisms of Rieske Oxygenases from Studying the Unproductive Activation of Dioxygen, Non-heme iron and 2-oxoglutarate enzymes catalyze cyclopropane and azacyclopropane formations, Obtaining precise metrics of substrate positioning in Fe(II)/2OG dependent enzymes using Hyperfine Sublevel Correlation Spectroscopy, Xe-pressurization studies for revealing substrate-entrance tunnels, and much more.Additional chapters cover A tale of two dehydrogenases involved in NADH recycling, Rieske oxygenases and/or their partner reductase proteins, Expression, assay and inhibition of 9-cis-epoxycarotenoi... dioxygenase (NCED) from Solanum lycopersicum and Zea mays, Biocatalysis and non-heme iron enzymes, In vitro analysis of the three-component Rieske oxygenase cumene dioxygenase from Pseudomonas fluorescens IP01, Structure and function of carbazole 1,9a-dioxygenase, Characterization of a Mononuclear Nonheme Iron-dependent Mono-oxygenase OzmD in Oxazinomycin Biosynthesis, and much more.

    • Chemokine Receptors in Health and Disease

      • 1st Edition
      • Volume 388
      • September 10, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 2 1 7 2 9
      • eBook
        9 7 8 0 4 4 3 2 2 1 7 3 6
      This volume reviews the current research in Chemokine Receptors and their role in physiological processes in the body, as well as their role in different pathological conditions. Chemokine Receptors are important for the migration of different types of cells, including immune cells to lymphoid organs and non-lymphoid organs thanks to the interaction with chemokines. The presence of different chemokine receptors on the cells’ surface was studied in normal states and diseases, some of them correlating with migration of subsets that play pro-disease roles or other help controlling the condition. Currently, state-of-the-art technology is helping researchers to better identify gene and protein expression of chemokine receptors at the single cell level. This large new data reveals the complexity of co-expression of various markers in the same cells and as well among different types of cells. Moreover, chemokine receptors are also helpful to identify different stages among subsets, and their correlation with better or worst responses in disease. Finally, treatments designed to inhibit or to block chemokine receptors are designed and tested at the preclinical and clinical level with different results. Here, we focus on the main chemokine receptors described in the current literature that play a role in health and diseases such as infections, autoimmune disorders, and cancer.

    • Unveiling the History of Transplantation

      • 1st Edition
      • September 9, 2024
      • Shi Chen
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 1 0 2 9
      • eBook
        9 7 8 0 4 4 3 2 9 1 0 3 6
      Unveiling the History of Transplantation: An Illustrated Review of the Boundaries, Fantasies and Realities covers the key international figures involved in organ transplantation and related fields. It includes a discussion of the contributions of many Nobel Prize winners in Physiology and Medicine. The book introduces the whole process of transplantation and the latest research progress of cell, tissue, and organ transplantation: from initial exploration to maturity and on to widespread application. A key feature of this resource is that it includes a large number of unique historical photos and material related to organ transplantation as collected by the author from libraries worldwide.

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