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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Commercializing the Stem Cell Sciences

      • 1st Edition
      • October 16, 2012
      • Olivia Harvey
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 6 0 2
      • eBook
        9 7 8 1 9 0 8 8 1 8 1 4 0
      Promising new developments in biomedical technology such as stem cell science are widely endorsed by governments keen to reduce spiralling healthcare costs, clinicians focused on patient care, and patients demanding revolutionary new treatments. Commercializing the stem cell sciences offers a comparative analysis of the commercial methods adopted in the global stem cell industries. It seeks to establish whether there is an optimum commercial model and to examine what emerging companies can learn from their predecessors. Following an introduction to stem cell sciences and the problems involved in their commercialization, the book begins with a discussion of stem cell treatments from a global perspective, and the role of innovation in the commercialization of biotechnology in general. In the second half of the book, chapters focus on the different strategies that can be employed and their relative risks and values, before a conclusion that looks at potential new developments in the field.

    • The Design and Manufacture of Medical Devices

      • 1st Edition
      • October 16, 2012
      • J. Paulo Davim + 1 more
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 7 2 5
      • eBook
        9 7 8 1 9 0 8 8 1 8 1 8 8
      Medical devices play an important role in the field of medical and health technology, and encompass a wide range of health care products. Directive 2007/47/EC defines a medical device as any instrument, apparatus, appliance, software, material or other article, whether used alone or in combination, including the software intended by its manufacturer to be used specifically for diagnostic and/or therapeutic purposes and necessary for its proper application, intended by the manufacturer to be used for human beings. The design and manufacture of medical devices brings together a range of articles and case studies dealing with medical device R&D. Chapters in the book cover materials used in medical implants, such as Titanium Oxide, polyurethane, and advanced polymers; devices for specific applications such as spinal and craniofacial implants, and other issues related to medical devices, such as precision machining and integrated telemedicine systems.

    • Therapeutic Antibody Engineering

      • 1st Edition
      • October 16, 2012
      • William R Strohl + 1 more
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 4 2 7 1
      • Hardback
        9 7 8 1 9 0 7 5 6 8 3 7 4
      • eBook
        9 7 8 1 9 0 8 8 1 8 0 9 6
      The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering.

    • Translational Endocrinology of Bone

      • 1st Edition
      • October 11, 2012
      • Gerard Karsenty
      • English
      • Hardback
        9 7 8 0 1 2 4 1 5 7 8 4 2
      • eBook
        9 7 8 0 1 2 4 1 5 8 5 9 7
      The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and others are being tested for diseases as different as osteoporosis, type-2 diabetes, and hypo-fertility. This book is a timely reference for both basic and clinical researchers in bone biology and endocrinology.

    • Metal Transporters

      • 1st Edition
      • Volume 69
      • October 5, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 3 9 0 3
      • eBook
        9 7 8 0 1 2 3 9 4 6 1 0 2
      This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others.

    • Challenges and Opportunities of Next-Generation Sequencing for Biomedical Research

      • 1st Edition
      • Volume 89
      • October 4, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 2 8 7 6
      • eBook
        9 7 8 0 1 2 3 9 8 2 7 3 5
      Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This volume features articles on Challenges and Opportunities of Next-Generation Sequencing for Biomedical Research.

    • Protein Folding in Silico

      • 1st Edition
      • October 4, 2012
      • Irena Roterman-Konieczna
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 1 7 6
      • Paperback
        9 7 8 0 0 8 1 0 1 6 7 1 8
      • eBook
        9 7 8 1 9 0 8 8 1 8 2 5 6
      Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks.

    • Applications of Viruses for Cancer Therapy

      • 1st Edition
      • Volume 115
      • October 3, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 8 3 4 2 8
      • eBook
        9 7 8 0 1 2 3 9 8 3 6 9 5
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "Applications of viruses for cancer therapy". With outstanding and original reviews, this volume covers topics such as Cancer Terminator Viruses and Approaches for Enhancing Therapeutic Outcomes, esign of improved oncolytic adenoviruses, and Adenovirus-based immunotherapies for cancer.

    • Advances in Genetics

      • 1st Edition
      • Volume 79
      • October 2, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 3 9 5 8
      • eBook
        9 7 8 0 1 2 3 9 8 2 8 4 1
      The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes imporatnt reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

    • Natural Product Biosynthesis by Microorganisms and Plants, Part A

      • 1st Edition
      • Volume 515
      • October 1, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 2 9 0 6
      • eBook
        9 7 8 0 1 2 3 9 4 6 2 7 0
      This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The first of 3 volumes covering Natural product biosynthesis by microorganisms and plants, it has chapters on such topics as Kinetics of plant sesquiterpene synthases, Terpenoid biosynthesis in fungi, and plant Type III polyketide synthases.

Related subjects

Biochemistry biophysics

Biotechnology

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Life sciences general

Molecular biology cellular biology and genetics

Physiology