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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Animal Models of Disease Part B

      • 1st Edition
      • Volume 188
      • June 14, 2024
      • English
      Animal Models of Disease, Part B, Volume 188 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Using C. Elegans as a model for Neurodegenerative disease: Methodology and Evaluation, Modelo Animal de Esclerosis Multiple: Encefalomielitis Autoimmune Experimental (EAE, New mouse model to study aneurysm development, Spinal Nerve Ligation: An Experimental Neuropathic Pain Model in Rats and Mice, Identifying therapeutic compounds for Autosomal Dominant Optic Atrophy (ADOA) through screening in the nematode C. elegans, Eµ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia, and much more.Other chapters cover Purification and characterization of kidney-infiltrating leukocytes in a mouse model of lupus nephritis, Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models, Assessing motor development and function in mouse models of neurodevelopmental disorders, Analysis of Gut Microbiota profile targeted to multi hypervariable regions of 16S rRNA in hypertensive heart failure rat model, and more.

    • Mitophagy in Health and Disease

      • 1st Edition
      • November 28, 2024
      • John J. Lemasters
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 2 6 0 3
      • eBook
        9 7 8 0 4 4 3 1 5 2 6 1 0
      Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention.This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role.

    • Nanostructured Drug Delivery Systems in Infectious Disease Treatment

      • 1st Edition
      • July 12, 2024
      • Sarwar Beg + 4 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 3 3 7 4
      • eBook
        9 7 8 0 4 4 3 1 3 3 3 6 7
      Nanostructured Drug Delivery Systems in Infectious Disease Treatment explores a broad range of promising approaches for the treatment of infectious diseases using the latest advancements in nanomedical technologies. The book opens with an introduction about infectious diseases and global burdens. There is also specific discussion and assessment of the global impact of viruses with an emphasis on COVID-19, Zika, and Ebola. Subsequent chapters provide detailed information about various novel nanotherapeutic strategies used for delivering drugs for the treatment of various types of viral, bacterial, and fungal disorders. This will be a valuable resource for graduates, researchers, industry professionals, and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner for the treatment of infectious diseases.

    • Mitochondrial Transplantation and Transfer

      • 1st Edition
      • August 3, 2024
      • Gokhan Burcin Kubat + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 8 5 8 9
      • eBook
        9 7 8 0 4 4 3 1 8 8 5 9 6
      Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, a volume in the Translational and Applied Bioenergetics series, offers a detailed overview of mitochondrial transplantation across fundamental biology, disease and early therapeutics research. Here, more than twenty experts in the field discuss transplantation and transfer of healthy mitochondria and define future steps to improve new therapeutic applications across a variety of diseases. Emphasis is placed on the physiology of mitochondrial transfer, isolation processes and their applications, transfer methods, and diagnostic and treatment use across cardiovascular, metabolic, and neurological diseases, among other disease types. Step-by-step instruction is provided around research protocols and methods discussed, along with careful attention to the ethical implications of mitochondrial transplantation research and application.

    • Thematic Approaches to COVID-19

      • 1st Edition
      • June 1, 2024
      • Rajkumar Rajendram + 3 more
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 8 3 1 2
      • eBook
        9 7 8 0 4 4 3 1 8 8 3 2 9
      Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.Linking Neuroscience and Behavior in COVID-19 examines the effect of both the virus and the pandemic on behavior and mental health. Chapters look at the burden of the COVID-19 pandemic on those with pre-existing conditions, including Parkinson's disease and multiple sclerosis. The ongoing consequences of the pandemic on the mental health of the broad populace are discussed. As well as the neurological effects of the virus itself, chapters discuss psychological concerns including depression and anxiety. Finally, the chapters also include aspects relevant to managing care and the treatment of conditions. A broad range of conditions preceding, caused by, or emerging for the first time during the pandemic are also detailed.Internation... and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide.Management... Body Systems, and Case Studies in COVID-19 describes the assessment and treatment of patients infected with the novel coronavirus that causes the varied symptoms of COVID-19. Detailing this multisystem disease and the organs and tissues affected, this volume features chapters on several body systems. Conditions affecting the respiratory, hematological, hepatobiliary, renal, gastrointestinal, nervous, musculoskeletal, and cardiovascular systems are addressed. The fundamental role of telemedicine during the pandemic is also discussed. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

    • Advances in Microbial Physiology

      • 1st Edition
      • Volume 84
      • June 3, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 4 0 9
      • eBook
        9 7 8 0 4 4 3 2 9 5 4 1 6
      Advances in Microbial Physiology, Volume 84 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include Mycobacterial Efflux systems, New insights in bacterial organophosphorus cycling: from human pathogens to environmental bacteria, Link between gut sulfidogenic bacteria and disease, The Formate-H2 Axis and its Importance for Microbial Physiology, Physiology of diazotrophs, Antibiotic efficacy, and Microbial metabolites as modulators of host physiology.

    • Redox Signaling

      • 1st Edition
      • Volume 162
      • July 30, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 4 4 4 0
      • eBook
        9 7 8 0 4 4 3 2 9 4 4 5 7
      Advances in Cancer Research, Volume 162 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

    • Computational Biology for Stem Cell Research

      • 1st Edition
      • January 12, 2024
      • Pawan Raghav + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 2 2 2 3
      • eBook
        9 7 8 0 4 4 3 1 3 2 2 1 6
      Computational Biology for Stem Cell Research seamlessly bridges the gap between the worlds of biomedical sciences and in silico computational methods. This book serves as a valuable resource for researchers and students, enabling them to grasp and delve into the intricacies of hematopoietic Stem Cells (HSCs) and mesenchymal Stem Cells (MSCs) through the lens of computational biology. This perspective sheds light on stem cell transplantation, translational research, and unique properties of stem cells like self-renewal and differentiation. In addition to introducing readers to stem cell-focused bioinformatics tools, this resource offers a clear pathway for effortlessly merging in silico methods with traditional in vitro and in vivo approaches.Computati... Biology for Stem Cell Research combines science and technology to showcase how computational methods transform stem cell research by reducing costs and enhancing investigations. The chapters uncover various approaches, from machine learning to genome analysis, for studying networks, protein interactions, dynamics, and the preprocessing of large datasets. The book aims to give readers a broad view of the advanced computational tools and methods extensively employed in stem cell research. Additionally, the book emphasizes the ongoing studies and tools yet to be developed for furthering stem cell research.

    • Intelligent Computing Techniques in Biomedical Imaging

      • 1st Edition
      • August 23, 2024
      • Bikesh Kumar Singh + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 9 9 9 2
      • eBook
        9 7 8 0 4 4 3 1 6 0 0 0 4
      Intelligent Computing Techniques in Biomedical Imaging: Methods, Case Studies, and Applications provides comprehensive and state-of-the-art applications of Computational Intelligence techniques used in biomedical image analysis for disease detection and diagnosis. The book offers readers a stepwise approach from fundamental to advanced techniques using real-life medical examples and tutorials. The editors have divided the book into five sections, from prerequisites to case studies. Section I presents the prerequisites, where the reader will find fundamental concepts needed for advanced topics covered later in this book. This primarily includes a thorough introduction to Artificial Intelligence, probability theory and statistical learning. The second section covers Computational Intelligence methods for medical image acquisition and pre-processing for biomedical images. In this section, readers will find AI applied to conventional and advanced biomedical imaging modalities such as X-rays, CT scan, MRI, Mammography, Ultrasound, MR Spectroscopy, Positron Emission Tomography (PET), Ultrasound Elastography, Optical Coherence Tomography (OCT), Functional MRI, Hybrid Modalities, as well as pre-processing topics such as medical image enhancement, segmentation, and compression. Section III covers description and representation of medical images. Here the reader will find various categories of features and their relevance in different medical imaging tasks. This section also discusses feature selection techniques based on filter method, wrapper method, embedded method, and more. The fourth section covers Computational Intelligence techniques used for medical image classification, including Artificial Neural Networks, Support Vector Machines, Decision Trees, Nearest Neighbor Classifiers, Random Forest, clustering, extreme learning, Convolution Neural Networks (CNN), and Recurrent Neural Networks. This section also includes a discussion of computer aided diagnosis and performance evaluation in radiology. The final section of Intelligent Computing Techniques in Biomedical Imaging provides readers with a wealth of real-world Case Studies for Computational Intelligence techniques in applications such as neuro-developmental disorders, brain tumor detection, breast cancer detection, bone fracture detection, pulmonary imaging, thyroid disorders, imaging technologies in dentistry, diagnosis of ocular diseases, cardiovascular imaging, and multimodal imaging.

    • Transfusion Medicine and Hemostasis

      • 4th Edition
      • November 16, 2024
      • Beth H. Shaz + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 6 0 1 4 4
      • eBook
        9 7 8 0 3 2 3 9 6 0 1 5 1
      **Selected for 2025 Doody’s Core Titles® in Laboratory Medicine**Transfusio... Medicine and Hemostasis: Clinical and Laboratory Aspects, Fourth Edition continues to be the only "pocket-size" quick reference for pathology and transfusion medicine for residents and fellows. It is helpful to all physicians and allied health professionals who order and administer blood components, cellular therapies, specialized factors for hemostatic abnormalities, coagulation testing, and those who consult and care for these often very ill patients. This book is ideal for pathology, medicine, surgery, and anesthesia residents, transfusion, hematology, and anesthesia fellows, and certified and specialized practitioners, as well as medical technologist in transfusion, cellular therapy, hematology, and coagulation. This new edition covers the many new developments that have occurred since the previous edition to include new blood products, new indications, or clinical conditions in which blood products are used. Similarly, new hemostasis testing is introduced as well as new clinical scenarios due the COVID-19 pandemic that area relevant to hemostasis and transfusion medicine. This includes COVID coagulopathy, Vaccine Induced Thrombotic Immune Thrombocytopenia, Pediatric reference range in coagulation testing, Platelet rich plasma and MNC products – CAR-T cells.

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