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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Enzymatic Basis of Detoxication Volume 1

      • 1st Edition
      • December 2, 2012
      • William B. Jakoby
      • English
      • Paperback
        9 7 8 0 1 2 3 9 5 8 8 3 9
      • eBook
        9 7 8 0 3 2 3 1 3 7 9 8 0
      Enzymatic Basis of Detoxication, Volume I focuses on the catalytic mechanisms and physiological expression of the enzymes that are involved in the detoxication of foreign compounds. The book explores foreign compound metabolism at the level of what specific enzymes can do. This book is organized into three sections and comprised of 17 chapters. The discussion begins with an overview of detoxication and covers both catalytic and non-catalytic removal of foreign substances, along with the general properties of the enzymes that are active in detoxication. The reader is then introduced to the physiological aspects of detoxication, paying particular attention to the kinetic aspects of metabolism and elimination of foreign compounds in animals, human genetic variation in detoxication enzymes, and how such enzymes are induced. The next section focuses on mixed function oxygenase systems and includes chapters on cytochrome P-450 and the detoxication reactions it catalyzes. The book also considers other oxidation-reduction systems, with reference to alcohol dehydrogenase, aldehyde reductase, aldehyde oxidizing enzymes, ketone reductases, xanthine oxidase and aldehyde oxidase, glutathione peroxidase, and superoxide dismutases. The final chapter is devoted to monoamine oxidase, its properties, substrate specificity, inhibitors, kinetics and mechanism, and multiple forms. Pharmacologists, toxicologists, and biochemists will find this book extremely helpful.
    • Sea Mammals and Oil: Confronting the Risks

      • 1st Edition
      • December 2, 2012
      • Joseph Geraci
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 4 0 0 7
      • eBook
        9 7 8 0 3 2 3 1 5 7 1 2 4
      Sea Mammals and Oil: Confronting the Risks summarizes the effects of spilled petroleum, or “oil”, on five groups of marine mammals, including seals, whales and dolphins, sea otters, polar bears, and manatees. It poses questions concerning the extent of oil spill effects on marine mammals; the vulnerability of each species; and the probable effects to humans, domestic animals, and laboratory animals. After an introduction to the composition and fate of petroleum and spill-treating agents in the marine environment, the book discusses the use of risk assessment and mathematical/compute... models in evaluating the effects of oil in marine mammal populations. Chapters 3 to 11 examine the ecological perspectives, physiologic, and toxic effects of oil on five mammal groups. The effect of oil on their behavior and the detection and avoidance of oil spill are also discussed. With a strong focus on risk assessment, this book is ideal for petroleum chemists and technologists, marine biologists, and veterinary medicine researchers.
    • Early Brain Damage V1

      • 1st Edition
      • December 2, 2012
      • C.R. Almli
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 4 6 9 6
      • eBook
        9 7 8 0 3 2 3 1 5 2 7 1 6
      Early Brain Damage, Volume 1: Research Orientations and Clinical Observations, is the first of two volumes that provide a comprehensive overview of the many facets of research on the topic of brain damage sustained early in life. The present volume features a collection of chapters oriented toward early brain damage in human clinical populations. It is organized into four parts. Part I presents research strategies and theoretical issues, such as intermodal compensation and evolutionary considerations, relating to early brain-damage phenomena. Part II presents research on animal models of infant neuropathological conditions such as hypoxia, fetal radiation, locomotor hyperactivity, and attentional disorders. Part III is concerned with short-term and long-term neurological effects of brain damage in children, including chapters on perinatal asphyxia, behavioral consequences of cerebral insult sustained during infancy, and correlates of early generalized brain dysfunction in children. Part IV presents chapters on cerebral lateralization and higher-order functions as they are altered by early brain damage. This book was written for researchers and professionals interested in the topic of brain damage, and especially those interested in the developmental brain-damage issues emanating from laboratory animal studies and human case reports.
    • Enzymatic Basis of Detoxication Volume 2

      • 1st Edition
      • December 2, 2012
      • William B. Jakoby
      • English
      • Paperback
        9 7 8 0 1 2 3 9 5 9 1 8 8
      • eBook
        9 7 8 0 3 2 3 1 3 8 2 0 8
      Enzymatic Basis of Detoxication, Volume II, reviews the state of knowledge on foreign compound metabolism at the level of what specific enzymes can do. The book attempts to provide a holistic view of the information gleaned from work with specific, purified enzymes encompassing as many mammalian sources as have been studied. The book is organized into two parts. Part I on conjugation reactions and related systems includes studies on the properties of glucuronide formation; the physiological function, assay, and purificatgion of function of bilirubin-glucuronos... glucuronosyltransfer... the roles of N- and O-methylation reactions and glutathione transferases in detoxication; and amino acid conjugation. Part II presents studies on hydrolytic systems, covering the role of epoxide hydrolase, carboxylesterases, and amidases in detoxication and the regulatory effects of these enzymes. This book provides pharmacologists and toxicologists with the biochemical view of detoxication, and biochemists with the corresponding pharmacological and toxicological aspects.
    • The Principles and Practice of Human Physiology

      • 1st Edition
      • December 2, 2012
      • O.G. Edholm
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 4 3 0 1
      • eBook
        9 7 8 0 3 2 3 1 4 3 4 5 5
      The Principles and Practice of Human Physiology reflects the progress of human physiology and presents developments through instrumentation and field work. This book is a continuation of previous texts on human physiology and survival, but focuses more on the aspect of human endeavor. The text comprises of 12 chapters with an additional article at the beginning (written by one of the authors) and a postscript regarding human experimentation and the ethics of it. Chapter 1 lays the foundation with a discussion on the history of human physiology. The succeeding chapters tackle and focus on aspects of physiology such as work, thermal, underwater, locomotor and postural, and stress. A chapter on instrumentation and physiological measurements is also featured in the text. The book will be a good source of valuable information to many students and professionals in the field of physiology, biology, medicine, and pharmacology.
    • NK Cells and Other Natural Effector Cells

      • 1st Edition
      • December 2, 2012
      • Ronald B. Herberman
      • English
      • eBook
        9 7 8 0 3 2 3 1 3 9 7 1 7
      NK Cells and Other Natural Effector Cells reviews the state of knowledge on NK cells and other natural effector mechanisms. The coverage of immune effector systems ranges from basic studies on their nature, regulation, and mechanisms of action to important practical issues such as their role in host resistance, their modulation by therapeutic intervention, and alterations of their activity in disease. The book is organized into 12 parts. Parts I and II examine the characteristics of NK cells and other natural effector cells, respectively. Part III focuses on the cell lineage of NK and related effector cells, providing evidence for or against T cell lineage, for or against macrophage lineage, and for or against other or separate lineage. Part IV deals with the genetics of natural resistance in the mouse and rat. Part V presents studies on the regulation of cytotoxic activity. Part VI examines the specificity of natural effector cells, covering the nature of target cell structures and the nature of recognition receptors in effector cells. Part VII discusses the cytotoxicity by cultured lymphoid cells while Part VIII turns to the mechanisms of cytotoxicity. Part IX deals with natural cell-mediated reactivity against primary tumor cells and against non-tumor targets. Part X examines NK cell tumors or the presence of NK cells at the site of tumor growth. Part XI presents clinical studies with natural effector cells. Part XII provides evidence for in vivo reactivity of natural effector cells.
    • The Retina A Model for Cell Biology Studies Part_1

      • 1st Edition
      • December 2, 2012
      • Ruben Adler
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 1 6 4 5
      • eBook
        9 7 8 0 3 2 3 1 4 0 7 2 0
      The Retina: A Model for Cell Biology Studies, Part I, is the first of a two-part series that details developments in the study of retinal cell biology. The book begins with some basic information about retinal structure and development followed by a discussion of the advantages of the retina as a model system for cell biology studies. It reviews some of the major events in the maturation of the retina pertinent to the assembly of neuronal circuits. The book describes studies of neuronal assembly in order to demonstrate that adhesion-based neuronal assembly may be the most elaborated example of a wider class of morphogenetic phenomena categorized as ""adhesion-guided multicellular assembly"" systems. The remaining chapters discuss in vivo and in vitro studies on trophic interactions in retinal development and in retinal degenerations; cell motility in the retina; molecular properties of vertebrate rod cells; the role of cyclic nucleotides in the metabolism and function of the retina; and the cellular and molecular aspects of photosensitive membrane turnover.
    • Clinical Biochemistry V3

      • 1st Edition
      • December 2, 2012
      • Herbert Spiegel
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 4 3 0 4
      • eBook
        9 7 8 0 3 2 3 1 5 7 4 2 1
      Clinical Biochemistry: Contemporary Theories and Techniques, Volume 3 broadens the scope of clinical biochemistry, discussing relevant aspects of serology, microbiology, monoclonal antibody techniques, and instrumentation. This volume includes the biochemical monitoring of cancer, use of chemical and physiochemical approaches to detecting and identifying etiological agents in clinical specimens, and monoclonal antibodies in clinical investigations. The serologic methods in disease diagnosis, instrumentation in clinical chemistry, and hemoglobin analysis and hemoglobinopathies are also deliberated. This text likewise covers the conventional microbiological techniques, serology of streptococcal infections, and impact of microprocessors on clinical instrumentation. This book is a good reference for clinicians interested in theories and techniques related to clinical biochemistry.
    • Pollution Ecology of Estuarine Invertebrates

      • 1st Edition
      • December 2, 2012
      • C.W. Jr. Hart
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 3 0 6 4
      • eBook
        9 7 8 0 3 2 3 1 5 1 0 7 8
      Pollution Ecology of Estuarine Invertebrates, as its companion volume ""Pollution Ecology of Freshwater Invertebrates"", aims to present the ecology of estuarine invertebrates and highlight some systematic interpretations. This book also discusses the knowledge about these invertebrates. It is a compilation of existing data at the time of writing, an attempt to introduce ideas and information, and a result of synthesis of systematic interpretations. This book consists of 12 chapters, each with a specific invertebrate as subject area. The invertebrates encompassed in this book are thread and bristle worms, Bryozoa, ostracods, copepods, crabs, shrimps, larval decapods, Cyathura, isopods (other than Cyathura), amphipods, clams, and snails. Each chapter gives a thorough discussion of the featured invertebrate according to some of the organism’s aspects, such as habitat, systematic, zoogeography, pollution ecology, life cycle, physiology, population, taxonomy, and distribution. This book is a valuable source for students, teachers, scientists, or researchers interested in estuarine invertebrates and pollution and study biology, environmental science, zoology, or even marine science.
    • Pheromones and Reproduction in Mammals

      • 1st Edition
      • December 2, 2012
      • John Vandenbergh
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 3 4 0 6
      • eBook
        9 7 8 0 3 2 3 1 5 6 5 1 6
      Pheromones and Reproduction in Mammals reviews current research findings on the role of pheromones in mammalian reproduction. Drawing on both quantitative laboratory studies and selected observational field studies, the book explores how animals actively deploy scent to facilitate sexual interactions and the functions of those scent signals during these interactions. Organized into two sections encompassing nine chapters, this volume begins with an overview of chemical signals and how they influence reproductive behavior in a variety of mammalian species. It then discusses the nature of chemical signals and olfactory perception; the role of chemical communication in mother-young interactions and in the reproduction of primates; how pheromones regulate puberty and the ovarian cycle; and pregnancy blocking by pheromones. The reader is also introduced to hormonal responses to primer pheromones; sensory physiology of pheromone communication; and the role of pheromones in the reproduction of domestic animals such as cattle, swine, sheep, and goats. Biologists and students of biology will find this book extremely informative.