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The Retina A Model for Cell Biology Studies Part_1
- 1st Edition - November 12, 2012
- Editor: Ruben Adler
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 1 2 1 6 4 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 4 0 7 2 - 0
The Retina: A Model for Cell Biology Studies, Part I, is the first of a two-part series that details developments in the study of retinal cell biology. The book begins with some… Read more
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Request a sales quoteThe Retina: A Model for Cell Biology Studies, Part I, is the first of a two-part series that details developments in the study of retinal cell biology. The book begins with some basic information about retinal structure and development followed by a discussion of the advantages of the retina as a model system for cell biology studies. It reviews some of the major events in the maturation of the retina pertinent to the assembly of neuronal circuits. The book describes studies of neuronal assembly in order to demonstrate that adhesion-based neuronal assembly may be the most elaborated example of a wider class of morphogenetic phenomena categorized as ""adhesion-guided multicellular assembly"" systems. The remaining chapters discuss in vivo and in vitro studies on trophic interactions in retinal development and in retinal degenerations; cell motility in the retina; molecular properties of vertebrate rod cells; the role of cyclic nucleotides in the metabolism and function of the retina; and the cellular and molecular aspects of photosensitive membrane turnover.
Contributors
Preface
Issues and Questions in Cell Biology of the Retina
I. Introduction
II. The Adult Retina
III. The Developing Retina
IV. The Pathological Retina
V. Concluding Remark
References
The Development of Retinal Networks
I. Introduction
II. The Development of Retinal Layers
III. Neurochemical Differentiation in the Retina
IV. Maturation of Retinal Networks
V. Summary
References
Differential Adhesion in Neuronal Development
I. Introduction
II. Neuronal Guidance Systems: Biological Studies
III. Molecular Mechanisms of Adhesion
IV. Neuronal Recognition and Differential Adhesion
References
Trophic Interactions in Retinal Development and In Retinal Degenerations. In Vivo and In Vitro Studies
I. Introduction
II. The Regulation of Neuronal Survival
III. The Search for "Trophic" and Other Regulatory Factors
IV. The Search for Molecules Controlling Survival and Differentiation of Retinal Neurons: In Vitro Studies
V. Concluding Remarks
References
Cell Motility in the Retina
I. Introduction
II. The Structural Machinery: The Cytoskeleton
III. Force-Producing Mechanisms
IV. Vertebrate Retinomotor Movements
V. Invertebrate Retinomotor Movements
VI. Cytoskeleton and Motility in RPE Cells
VII. Morphological Aspects of Retinal Synaptic Modulation
VIII. Alignment of Photoreceptors
IX. Concluding Remarks
References
Molecular Dynamics of the Rod Cell
I. Structure of the Rod Cell
II. Disk Membrane of the Rod Cell Outer Segment
III. Rhodopsin: The Photoreceptor Protein
IV. Light-Dependent Biochemistry of the Rod Cell
References
Cyclic Nucleotides in Retinal Function and Degeneration
I. Introduction
II. Cyclic Nucleotide Metabolism in Rod-Dominant Retinas
III. Cyclic Nucleotides in Cone-Dominant Retinas
IV. Abnormalities in Cyclic Nucleotide Metabolism in Retinal Degenerations
V. Future Prospects
References
Photosensitive Membrane Turnover: Differentiated Membrane Domains and Cell-Cell Interaction
I. Introduction
II. Synthesis and Assembly of Photosensitive Membrane
III. Disk Shedding and Phagocytosis
IV. Regulation of Membrane Turnover
V. Summary
References
Index
- No. of pages: 380
- Language: English
- Edition: 1
- Published: November 12, 2012
- Imprint: Academic Press
- Paperback ISBN: 9780124121645
- eBook ISBN: 9780323140720
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