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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Molecular Basis of Lysosomal Storage Disorders

      • 1st Edition
      • December 2, 2012
      • John Barranger
      • English
      • Paperback
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      Molecular Basis of Lysosomal Storage Disorders contains the proceedings of the 1983 Conference on the Molecular Basis of Lysosomal Storage Disorders, held at the National Institutes of Health in Bethesda, Maryland. The papers focus on the molecular biology of, and therapeutic approaches to, lysosomal storage disorders, such as mucopolysaccharidose... sphingolipidoses, and Gaucher disease. Organized into six sections comprised of 29 chapters, this book begins with an overview of enzymes, activator proteins, and stabilizers that underlie lysosomal storage disorders. It then discusses some developments in enzyme purification, receptors for glycoprotein enzymes, factors that control endocytosis, and the intracellular fate of lysosomal hydrolases. Some chapters explain the enzyme biosynthesis, bone marrow transplantation, and enzyme replacement, along with cell hybridization, chromosome localization, phenotype discrimination, and cloning of genes for human lysosomal enzymes. This book is helpful to biochemists, physiologists, pathologists, geneticists, clinical investigators, and practicing physicians concerned with the study, care, and treatment of patients with hereditary metabolic disorders, as well as undergraduate and graduate level students involved in research in this discipline.
    • Molecular Control of Proliferation and Differentiation

      • 1st Edition
      • December 2, 2012
      • John Papaconstantinou
      • English
      • Paperback
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      • Hardback
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      Molecular Control of Proliferation and Differentiation documents the proceedings of the 35th symposium of The Society for Developmental Biology entitled "Molecular Control of Proliferation and Differentiation," held at Asilomar, Monterey Peninsula, California, June 8-11, 1976. The contributions made by researchers at the symposium are organized into seven parts. Part I presents a paper on cell communication in embryological development. Part II includes studies on growth factors, including fibroblast growth factor and epidermal growth factor. Part III examines the factors affecting nerve cell differentiation and function. It includes papers on nerve growth factor and peptides as central nervous system neurotransmitters. Part IV focuses on cell interactions in blood cell development. It includes studies on factors affecting the differentiation of blood cells and the proliferation of hemopoietic stem cells in vitro. Part V examines cell interactions in the immune system. Part VI deals with cell interactions in organogenesis. Part VII covers the factors effecting differentiation in lower eukaryotes.
    • Viral Transformation and Endogenous Viruses

      • 1st Edition
      • December 2, 2012
      • Albert Kaplan
      • English
      • Paperback
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      Viral Transformation and Endogenous Viruses is a collection of papers presented at the symposium on ""Viral Transformation and Endogenous Viruses"" held at Vanderbilt University on April 1-2, 1974. Contributors discuss the viral function(s) responsible for the transformation of the cells that are infected with oncogenic viruses, emphasizing the type of changes that characterize transformed cells and the regulatory mechanisms that are altered after malignant transformations. This volume is organized into 10 chapters and begins with an overview of DNA-containing tumor viruses, particularly Simian Virus 40 (SV40) and its mutants with DNA deletions, insertions, and duplications. The integration and transcription of adenovirus DNA is considered, along with the characteristics of temperature-sensitiv... mutants of these viruses. The reader is then introduced to the chemistry and biology of RNA-containing tumor viruses, which are useful reagents to study neoplastic transformation both in vivo and in vitro. A major aspect of these viruses concerns the analysis of their genome at the chemical and genetic levels. The last part of the book is devoted to biochemical and genetic analyses of endogenous viruses isolated from avian cells. This book is a valuable resource for scientists and investigators in fields such as pathology, molecular virology, molecular biology, microbiology, oncology, and biochemistry.
    • Stem Cells of Renewing Cell Population

      • 1st Edition
      • December 2, 2012
      • A.B. Cairnie
      • English
      • Paperback
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      Stem Cells of Renewing Cell Populations constitutes the proceedings of the ""Stem Cells in Various Tissues"" symposium, organized as a tribute to Charles P. Leblond on the occasion of his 65th birthday. The pioneering studies of Dr. Leblond on the kinetics of cell populations led him to the identification and analysis of the behavior of the ""stem cells,"" which are at the origin of each cell line. This book focuses on the study of stem cells in various organs, including intestine, epidermis, hematopoietic and lymphoid tissues, and testis, under normal steady state conditions. It examines the behavior of stem cell in these organs, such as cell cycle and differentiation and regulation using several distinct techniques. The concluding part discusses the behavior of hematopoietic stem cell during growth and aging, as well as its distribution and dynamics in tumor-bearing tissues. Workers from many disciplines, including biologists, stem cell biologists, and regenerative medicine researchers will greatly benefit from this book.
    • Handbook of The Biology of Aging

      • 3rd Edition
      • December 2, 2012
      • Edward Schneider
      • English
      • Paperback
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      Handbook of the Biology of Aging, Third Edition presents the methodology for biological aging studies. This book discusses the three main sources of influence on aging, namely, the biological, the psychological, and the social. Organized into six parts encompassing 19 chapters, this edition begins with an overview of the pathophysiology of the processes that lead to the array of age-dependent conditions. This text then examines the clinical studies on aging, with emphasis on study design, subject selection and characterization, and the clinical relevance of the aging changes studied. Other chapters consider various topics related to aging, including circadian rhythms, protein modifications with aging, special senses, and the adrenocortical axis. This book discusses as well the study of immune dysfunction in the aged organism. The final chapter deals with odor deficits as well as subtle taste changes associated with aging. This book is a valuable resource for scientists, gerontologists, graduate students, and professionals.
    • The Laws of Energy Consumption in Nutrition

      • 1st Edition
      • December 2, 2012
      • Max Rubner
      • English
      • Paperback
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      The Laws of Energy Consumption in Nutrition focuses on nutrition education. The book first discusses standard values for measuring calories and the relationship between food intake and energy consumption. Exclusive fat diet; respiratory and calorimetric experiments of short duration; and the effects of protein diet on animals are described. The text also focuses on particular dynamic effect of food substances; the effect of diet on deposit and metabolism at various thermal conditions; and the compensation theory of nutritional effects. The book looks at heat regulation in fasting animals; comparison between the amount of heat that can be saved through regulation and the increase in energy metabolism caused by food intake; and chemical regulation in fed animals at low temperatures. The text discusses chemical and physical heat regulation and their importance to energy change in animals; mechanisms of heat regulation in conditions of full nutrition and starvation in animals; and considerations of heat regulation in human. The book is a vital source of data for readers wanting to study nutrition.
    • Modern Methods in the Analysis and Structural Elucidation of Mycotoxins

      • 1st Edition
      • December 2, 2012
      • Richard J. Cole
      • English
      • Paperback
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      Modern Methods in the Analysis and Structural Elucidation of Mycotoxins presents available methods of analysis and structural elucidation of mycotoxins by recognized experts in the various disciplines. The approach in each chapter of the book is to present each method initially in theoretical terms and then to review the method as it specifically applies to the analysis and/or structural elucidation of mycotoxins. Comprised of 15 chapters, the book's opening chapters deal with screening, sampling, and survey methods for mycotoxins and toxigenic fungi. This is followed by chapters dealing mostly with methods for structural elucidation, such as NMR and X-ray crystallography and IR and UV spectroscopy, as well as biosynthetic techniques. Significant chapters consider the analytical methods for mycotoxin analyses, including enzyme-linked immunosorbent assay system and tandem mass spectrometry. The concluding chapter examines the mycotoxin analytical problem in taxonomic or ecological terms. This book is of value to food and feed researchers, scientists, and manufacturers who are interested in product contamination control.
    • The Islets of Langerhans

      • 1st Edition
      • December 2, 2012
      • S.J. Cooperstein
      • English
      • Paperback
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      The Islets of Langerhans: Biochemistry, Physiology, and Pathology reviews the state of knowledge in the complex phenomena involved in the functioning of the multiendocrine organ, the islet of Langerhans, and the various influences that can lead to its abnormal functioning. The volume highlights major gaps in knowledge and indicates the directions for research on the major functioning of this organ and the defects leading to its major pathology, diabetes mellitus. The book is organized into three parts. Part I provides the necessary background information on the nature and development of the islet of Langerhans. It includes studies on the evolution of knowledge of the ever-increasing number of cell types found in islet tissue; and fetal development of the functional capacities of the islet cells. Part II is devoted to the synthesis and secretion of islet hormones, beginning with a chapter on the membrane transport systems of islet tissue as a prelude to subsequent examination of their role in the regulation of these processes. Part III examines the effects of deleterious conditions and agents on the morphology and function of islet cells. This book is intended for researchers in endocrinology, particularly those interested in pancreatic hormones, graduate students in endocrinology, and medical endocrinologists interested in diabetes. It will also be useful to physiologists and biochemists studying peptide synthesis and secretion.
    • Clinical Biochemistry

      • 1st Edition
      • December 2, 2012
      • Herbert Spiegel
      • English
      • Paperback
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      Clinical Biochemistry: Contemporary Theories and Techniques, Volume 1 is a collection of papers that deals with the biochemistry of aging, managerial techniques, the evaluation of kits, and autoimmune diseases. One paper discusses laboratory management for clinical chemists—the administration of people, the application of budgets, the planning process, and the adoption of decision-making strategies. The government has also issued federal legislations such as the "Clinical Laboratory Improvement Act, 1967" and the "National Heath Planning and Resources Development Act of 1974" which are changing the way laboratories are doing business. Another paper describes areas of safety concerns specific to the environment of the laboratory that require technologies not readily available to the laboratory technician. These safety problems concern radioactivity and infectious etiologic agents. Another paper discusses criteria recommendations for kit selection in clinical laboratories, for example, the list issued by the Center for Disease Control and the standards issued by the National Committee for Clinical Laboratory Standards. Another paper explains the uses of mathematics in clinical chemistry, including the application of the Allen Correction, the Henderson-Hasselbalc... Equations, empirical curve fitting, standard deviation, standard error. Other papers present guidelines in dealing with autoimmune diseases and in determining specific proteins in plasma, cerebrospinal fluid, and other biological fluids. This collection is suitable for clinic and laboratory administrators and managers, for chemical chemists, and investigators or technicians involved in laboratory work.
    • The Recombination of Genetic Material

      • 1st Edition
      • December 2, 2012
      • K Low
      • English
      • Paperback
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      The Recombination of Genetic Material aims to introduce the elementary properties of recombinational phenomena. Genetic recombination is a favorite research topic in biology due to its significance. In fact, a simple recombination event can have a profound effect and sometimes can mean the difference between the survival and the demise of an organism. Examples of this are provided in this book. This work also describes numerous recombination systems, mechanisms of the major types of recombination, and the macroscopic products of this biological process. Molecular analyses of recombination enzymes and substrates that have been identified or implicated are also shown. This book will be valuable as a reference material to those interested in this field of study.