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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Theory and application of Microbiological Assay

      • 1st Edition
      • December 2, 2012
      • William Hewitt
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 7 2 1 5
      • eBook
        9 7 8 0 3 2 3 1 5 5 2 8 1
      Theory and Application of Microbiological Assay first presents an overview of microbiological assay, including general principles, basic techniques, capabilities, and limitations. This book also explains when to use a certain microbiological assay for specific analysis, citing examples to further clarify the matter. Some chapters discuss the test organisms and solutions, wherein test solutions are the final dilutions at a series of two or more concentrations that have been prepared from reference standard and unknown for application to the test system. Other chapters explore the various aspects of agar diffusion assays, tube assays, and diffusion assays. The book further looks into the quality control procedures, assay design and evaluation, and assay replication. This book will serve as an introduction to newcomers to the field and as a reference source for established workers in microbiological assay.
    • Human Cholinesterases and Anticholinesterases

      • 1st Edition
      • December 2, 2012
      • Hermona Soreq
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 2 6 6 9
      • eBook
        9 7 8 0 3 2 3 1 5 5 7 3 1
      Human Cholinesterases and Anticholinesterases summarizes the many fundamental concepts of human cholinesterases (ChEs) and their inhibitors. This book is divided into three chapters that represent human cholinesterase research studies from different points of view. Chapter 1 deals with the biochemical and biological background of human ChEs. This chapter also examines the molecular polymorphism, genomic origin, genetic variants, and biological roles of these enzymes. Chapter 2 provides the molecular characterization of human ChE genes and their multileveled regulation, with a special emphasis on butyrylcholinesteras... Chapter 3 discusses the scientific, ecological, and clinical implications of the studies presented in the previous chapters. Protein scientists, engineers, and researchers will find this work invaluable.
    • Regulation of HMG-CoA Reductase

      • 1st Edition
      • December 2, 2012
      • Benjamin Preiss
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 7 0 8 6
      • eBook
        9 7 8 0 3 2 3 1 5 5 1 4 4
      Regulation of HMG-CoA Reductase is a nine-chapter text that focuses on the research developments in the regulation of HMG-CoA reductase enzyme and cholesterol biosynthesis. This book deals first with the role of cholesterol in the regulation of its own biosynthesis and the work involving compactin and related competitive inhibitors of HMG-CoA reductase. The subsequent chapters examine the reversible phosphorylation of HMG-CoA reductase in hormonal and other short-term physiological changes and the structure and properties of the enzyme, including evidence for modulation of enzyme activity and structure unrelated to phosphorylation. These topics are followed by discussions on the regulation of reductase in the biosynthesis of ubiquinone, dolichols, and isopentenyl-tRNA and the regulation of reductase activity in extrahepatic tissues. This text further explores the contributions made through the use of cultured cells and their genetic manipulation, with emphasis on the great potential of this approach. The concluding chapters address the status of the low-density lipoprotein pathway and related mechanisms. These chapters also consider the regulation of human hepatic HMG-CoA reductase and the special problems inherent in work with human tissues. Enzyme scientists and researchers and graduate students will find this book invaluable.
    • Genetics of Bacterial Diversity

      • 1st Edition
      • December 2, 2012
      • David A. Hopwood + 1 more
      • English
      • eBook
        9 7 8 0 0 8 0 9 8 4 0 8 7
      While other texts in this area deal almost solely with the "workhorse strain" Escherischia coli, Genetics of Bacterial Diversity is the first to deal with genetics and molecular biology of the wide range of other bacteria, which carry out a whole spectrum of important scientific, medical, agricultural, and biotechnological activities. Taking genetic diversity as its theme it illustrates a range of interesting phenomena such as genetic systems controlling pathogenicity, symbiosis, chemotaxis, metabolic characteristics, and differentiation. With each chapter written by acknowledged experts, this definitive book contains up-to-the-minute information on this rapidly developing field.Written by leading experts, this text--aimed at graduate-level students and above--describes the genetics and molecular biology of a wide range of bacteria.
    • The Physiology and Pharmacology of the Microcirculation

      • 1st Edition
      • December 2, 2012
      • Nicholas Mortillaro
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 4 2 9 3
      • eBook
        9 7 8 0 3 2 3 1 4 7 4 7 7
      The Physiology and Pharmacology of the Microcirculation, Volume 1 discusses the biochemistry, metabolism, pharmacology, and physiology of the general microcirculation. This volume is organized into nine chapters that explore the microcirculation in several organ systems, such as brain, eye, heart, and kidney. The introductory chapters treat the biochemistry of isolated elements of the microvasculature, with special emphasis on the central nervous system. These chapters also explore the microvascular element and the vascular smooth muscle, focusing on their ultrastructural characteristics, innervation, and contraction-relaxati... and the effects of both endogenous and pharmacological vasoactive substances on vascular smooth muscle. The subsequent chapters deal with the exchange mode of the microcirculation; the mechanisms involved in the regulation of transcapillary fluid exchange; and the permeability of capillaries to small and large molecules in a variety of tissues. A discussion on the control mechanisms modulating microcirculatory dynamics is also included. The remaining four chapters are organized to deal with the microcirculation process in selected organs.
    • Extracellular Matrix Genes

      • 1st Edition
      • December 2, 2012
      • Charles Boyd
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 4 5 4 0
      • eBook
        9 7 8 0 3 2 3 1 5 7 6 6 7
      Extracellular Matrix Genes provides some of the interesting complexities of the structure of the entire family of extracellular matrix genes. This book illustrates the permanent role that molecular biology and molecular genetics play in the detailed understanding of the normal biology of extracellular matrix. Organized into 10 chapters, this book begins with an overview of the structural and sequence aspects of the entire family of genomic sequences with a view to establishing common functional domains among collagens and their genes. This text then examines the status of the literature concerning human types. III and V. Other chapters consider the FACIT collagen gene family. This book discusses as well the development in understanding the structure of small proteoglycan core proteins and their role in proteoglycan biosynthesis and function as a result of their molecular cloning and expression. The final chapter deals with mutations in collagen genes. This book is a valuable resource for biochemists.
    • Times, Cells, and Aging

      • 2nd Edition
      • December 2, 2012
      • Bernard Strihler
      • English
      • Paperback
        9 7 8 0 1 2 3 9 4 1 7 7 0
      • eBook
        9 7 8 0 3 2 3 1 6 1 6 9 5
      Time, Cells, and Aging, 2nd Edition presents the mechanics of cell function and the relevant implications of the molecular-genetic view to the aging phenomena. This book explores the biology of the aging process. Comprised of 11 chapters, this edition starts with an overview of the causes and mechanisms underlying the gradual deterioration of structure and function characteristics of aging. This text then examines the two aspects of the behavior of man, including the reasoned conscious behavior and the greater dependence on reaction patterns predicted on the successful responses of the past. Other chapters explore the relationship between aging and mortality rate in animals, which is a result of an organism’s deceasing ability to function optimally in carrying out his vital functions. The final chapter deals with the implementation of a research plan relevant to understanding the primary mechanisms of the aging process. This book is a valuable resource for gerontologists, biologists, and molecular biologists.
    • Physiology of the Amphibia

      • 1st Edition
      • December 2, 2012
      • Brian Lofts
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 4 6 4 6
      • eBook
        9 7 8 0 3 2 3 1 4 3 7 9 0
      Physiology of the Amphibia, Volume III consists of 10 chapters beginning with a discussion on amphibian color changes and the various aspects of the molting cycle. Possessing a skin more suitable for life in the water, the amphibians need to prevent excessive water loss from their body to the environment; hence, an additional mechanism for reducing the hazards of desiccation in many anuran species is described. This book also tackles the physiology of amphibian cells in culture. Furthermore, the animals' nervous, visual, and auditory systems; their immunity; and metamorphosis are explained in this text. This reference will be useful to general biologists and to students with interests in animal physiology.
    • Sequence Analysis in Molecular Biology

      • 1st Edition
      • December 2, 2012
      • Gunnar Von Heijne
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 7 0 6 0
      • eBook
        9 7 8 0 3 2 3 1 6 0 2 8 5
      Sequence Analysis in Molecular Biology: Treasure Trove or Trivial Pursuit presents the methods for sequence analysis of DNA and proteins. This book contains eight chapters that consider the sequence analysis either directly on a microcomputer or using one of the main sequence/programs data banks. This book starts with a description of the main nucleic acid and protein sequence data banks, followed by a short section on the ""housekeeping aids"" that the computer can provide during a sequencing project. Chapters 4 and 5 deal with nucleic acid and protein sequence analysis. Chapter 6 treats algorithms for homology searching and sequence alignments. Chapter 7 presents some selected examples of how computer modeling can help decide whether an observed sequence pattern is significant or not, and how computer simulation is sometimes used to get a feeling for the behavior of intrinsically complex sequence-dependent processes. Chapter 8 contains some comments on the role of theoretical sequence analysis in molecular biology. This book is directed toward molecular biologists.
    • Water Relations of Foods

      • 1st Edition
      • December 2, 2012
      • R Duckworth
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 3 7 1 7
      • eBook
        9 7 8 0 3 2 3 1 4 2 8 6 1
      Water Relations of Foods consists of proceedings of an international symposium on “Water Relations of Foods” held in Glasgow, in September 1974. Organized into seven sections, the book presents the various papers delivered in the symposium. It describes the physical chemistry of water in simple systems as well as in the more complex food component systems (carbohydrates, lipids, and proteins), with emphasis on the nature of the intermolecular forces involved. It also reports the various techniques used to measure the state of water in food and in model systems made up of food components. Furthermore, the book discusses water activity and the growth of food spoilage and pathogenic organism; water relations of enzymic and non-enzymic deteriorative reactions in food; effects of freezing and thawing of water in food systems; and the significant aspects of food quality as affected by water in the system. Lastly, the modification of the state of water in foods is addressed. This publication will indeed help advance the understanding on this field of interest.