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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • MHPC: Basic Mechanisms and Psychopathology

      • 1st Edition
      • December 2, 2012
      • James Maas
      • English
      • Paperback
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      • eBook
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      MHPG: Basic Mechanisms and Psychopathology discusses the interactions between clinical biological psychiatry and basic neuropsychopharmacol... Composed of 10 chapters, this book focuses on the role of 3-methoxy-4-hydroxyp... (MHPG) in psychiatric disorders, particularly, in depression and mania. The book first examines the enzyme systems that produce MHPG in the brain and the features of these enzymes that could be used to reconcile several contradictions with regard to the origin of urinary MHPG. It then discusses the correlation between changes in impulse flow in central noradrenergic neurons of the locus ceruleus and MHPG levels in brain. The subsequent chapters cover the theoretical issues and empirical data dealing with the interrelationships between plasma and urinary measures of MHPG and central nervous system noradrenergic function. Measurement methods of MHPG in plasma, cerebrospinal fluid, and urine are also presented. The concluding chapters deal with the relevant human studies in patient and nonpatient populations concerning the role of MHPG in depressive disorders, with particular emphasis on clinical studies in childhood and adolescence. This book is of value to clinical biologists, psychiatrists, and neuropsychopharmacol...

    • Organ Culture

      • 1st Edition
      • December 2, 2012
      • J Thomas
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Organ Culture provides information pertinent to the fundamental aspects of the study of autodifferentiation. This book discusses the physiological differentiation, the action of substances that inhibit or stimulate growth, and the interactions of associated organs. Organized into 10 chapters, this book begins with an overview of the differentiation of embryonic organs in natural media. This text then presents the study of differentiation in synthetic solid or liquid media and explains the biochemical and physiological requirements of the tissues. Other chapters consider the problems of sexual differentiation and intersexuality in vitro by providing a comparative study of avian and mammalian embryos. This book analyzes as well the interactions between hormones, inhibitor substances, and receptor organs in vitro. The final chapter deals with the study of organ chimeras in vitro and the related study of the organ culture of malignant tumors. This book is a valuable resource for embryologists and research workers.

    • Regulation of Macromolecular Synthesis By Low Molecular Weight Mediators

      • 1st Edition
      • December 2, 2012
      • Gebhard Koch
      • English
      • Paperback
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      • Hardback
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      Regulation of Macromolecular Synthesis by Low Molecular Weight Mediators contains the proceedings of the Workshop on Regulation of Macromolecular Synthesis by Low Molecular Weight Mediators held at Hamburg on May 29-31, 1979. The book discusses the functions and metabolism of guanosine 3',5'-bis(diphosphat... the purine nucleotides and sporulation; and the highly phosphorylated nucleotide in eukaryotes. The text also describes the alteration of translational mechanisms, as well as 2,5-oligoadenylic acid and interferon.

    • Heredity

      • 1st Edition
      • December 2, 2012
      • I Gunsalus
      • English
      • Paperback
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      • eBook
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      The Bacteria: A Treatise on Structure and Function, Volume V: Heredity explores the role of bacterial genetics in heredity. The book includes chapters on genetic fine structure, genetic replication, and gene-enzyme relationships, along with gene transduction, bacterial episomes, and genetic recombination. This volume is organized into 10 chapters and begins with an overview of conjugation as a mechanism of genetic exchange in bacterial species such as Escherichia coli, Salmonella typhosa, Pseudomonas aeruginosa, Vibrio cholera, and Serratia marcescens. The book then discusses transduction, its uses and evolutionary implications, and the nature of the transducing particle as well as the transduction of galactose genes by bacteriophage lambda. The reader is also introduced to transformation and its use in genetic analysis, along with bacterial episomes and genetic transfer; genetic recombination and other genetic phenomena in streptomycetes; and DNA replication. The book concludes by explaining how bacteria should be defined from a biological standpoint. This book is a valuable source of information for geneticists, biochemists, biologists, and research workers involved in the biological sciences.

    • Early Influences

      • 1st Edition
      • December 2, 2012
      • Gilbert Gottfried
      • English
      • Paperback
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      • Hardback
        9 7 8 0 1 2 6 0 9 3 0 4 9
      • eBook
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      Studies on the Development of Behavior and the Nervous Systems, Volume 4: Early Influences discusses the effect of various exogenous factors on the early development of behavior and the nervous system. This volume is divided into three sections encompassing nine chapters that specifically consider the prenatal and postnatal effects of drugs, radiation, hormones, nutrition, sensory experience, trauma, and environmental enrichment. Section 1 initially describes the principles of teratology as they apply to functional or behavioral manifestations of prenatally administered drugs. This topic is followed by discussions on the radiation effects on developing mammals; the mechanisms of malformation involved; the use of malformed animals to find correlations between developing brain and behavior; and radiation hazard prevention in humans. This section also deals with the influence of hormones early in life upon sex differences in the behavior of adults and the effects of prenatal stress on offspring behavior. Section 2 examines the significance of proper maternal nutrition in early brain development and the evidence for long-term effects of undernutrition during the brain growth spurt. This section also looks into the behavioral implications of the various methods for producing early undernutrition in experimental animals and their possible relevance to the human condition. Section 3 describes the manipulation of early sensory experience, from total removal of sensory input to modification of stimulus quality, and the effects of such manipulations on the auditory, gustatory, olfactory, tactile, and visual systems. This section also provides an overview of auditory maturation and the consequences of acoustic trauma in the adult. This book is of great value to neurodevelopmental biologists and researchers.

    • Immune Surveillance

      • 1st Edition
      • December 2, 2012
      • Richard T. Smith
      • English
      • Paperback
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      • Hardback
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      Immune Surveillance deals with the issues regarding tumor immunology and surveillance, in which the central theme is all about the life span of the mammalian host that is depleted by the environment with mutagenic agents and solutions. The book is divided into six chapters. It includes discussions on the organization and modulation of cell membrane receptors, as well as the origin and expression of membrane antigens. It also covers the topics on the triggering mechanisms for and effector mechanisms activated by the cellular recognition. These topics analyze and evaluate alternatives for the recognition and destruction mechanisms in the knowledge of cell cooperation and requirements for immune recognition. A chapter provides discourse on a solution for the paradox of thriving tumors based on the demonstrable in vitro host immunity. Another discusses the generation of antibody diversity and the theory of self-tolerance. The last chapter explains the evaluation of the evidence for immune surveillance. This reference will be invaluable to those who specialize in immunology.

    • Brainstem Control of Spinal Cord Function

      • 1st Edition
      • December 2, 2012
      • Charles D. Barnes
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Brainstem Control of Spinal Cord Function summarizes the research findings on major bulbospinal control systems. It explores how sensory, reflex-evoking inputs to the central nervous system (CNS) modulate descending control signals and how descending control signals regulate the excitability or gains of the segmental reflex arcs. It also looks at the role of the reticulospinal system in the control of movement, the effects of labyrinth and neck inputs on vestibulospinal and medullary reticulospinal neurons, the behavioral significance of the raphe-spinal system, locus coeruleus control of spinal cord activity, and the influence of allergic encephalomyelitis on monoaminergic neurotransmission. Organized into six chapters, this book begins with an overview of the findings on how human spinal reflexes are modulated. It then discusses the reticulospinal system, its role in the control of movements, and its involvement in responses elicited from several sensory systems. In addition, the book examines the response characteristics of the vestibulospinal and the medullary reticulospinal systems based on experiments on labyrinthine and neck input. Other chapters focus on all aspects, including motor and sensory, of the raphe-spinal system, physiological aspects of coerulospinal neurons, and the mechanisms by which allergic encephalomyelitis results in hindlimb paralysis. This book is a valuable resource for physiologists and students of physiology.

    • Molecular Genetics Pt 3

      • 1st Edition
      • December 2, 2012
      • Herbert Taylor
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Molecular Genetics, Part III: Chromosome Structure explores the structure and modification of DNA, chromatin, and higher order organization and possible subunits of chromosomes at the molecular level. It describes major changes in concepts of chromatin structure and packaging of DNA based on studies of nuclease digests and electron micrographs; the role of restriction endonucleases in molecular genetics; the involvement of DNA topoisomerases in concerted breaking and rejoining of DNA backbone bonds; enzymatic methylation of DNA; and transcriptional units in eukaryotic chromosomes. Organized into seven chapters, this volume begins with an overview of the general properties of type I and type II restriction enzymes, basic aspects of restriction enzyme technology, and applications of restriction enzyme technology to the study of chromosome structure and function. It then discusses recombinant DNA technology; possible biological roles of DNA topoisomerases; recognition and control sequences in nucleic acids; composition and substructure of nucleosomes; analysis of chromosome fibers by electron microscopy; organization of fibers into chromosomes; and functional aspects of organization of chromosome fibers. Molecular biologists, geneticists, scientists, and electron microscopists will find this book extremely helpful.

    • Cellular Basis of Chemical Messengers in the Digestive System

      • 1st Edition
      • December 2, 2012
      • Morton Grossman
      • English
      • Paperback
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      Cellular Basis of Chemical Messengers in the Digestive System contains the proceedings of an international symposium on the cellular basis of chemical messengers of the digestive system held in Santa Monica, California, on January 16, 17, and 18, 1980. The papers explore the entire spectrum of problems related to the cellular aspects of chemical messengers in the digestive system, with emphasis on which amines and peptides serve these functions and in which neurons and endocrine-paracrine cells each kind of chemical messenger is found. This book is comprised of 28 chapters divided into six sections and begins by considering the nature of gut peptides and their possible functions. The discussion then turns to the diffuse neuroendocrine system and the phylogeny of the gastroenteropancreat... neuroendocrine system. Methods such as immunocytochemistry, electron immunohistochemistry... and electron microscopy autoradiography are then described. The following chapters focus on the function and morphology of endocrine-paracrine cells; immunochemical characterization of peptides in endocrine cells and nerves; Langerhans islets as the neuro-paraneuronal control center of the exocrine pancreas; and regulation of metabolism by gastroenteropancreat... peptides. The final section presents experimental results, including in vitro studies of canine pseudo-islets and of the mechanism of gastrin release. This monograph will be of interest to physiologists and other practitioners in the field of medicine.

    • General Cytochemical Methods

      • 1st Edition
      • December 2, 2012
      • J.F. Danielli
      • English
      • Paperback
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      • eBook
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      General Cytochemical Methods, Volume II focuses on methods and techniques employed in the studies of the biochemistry of cells. Composed of eight chapters, the book looks at immersion refractometry of living cells by phase contrast and interference microscopy. Areas considered include interpretation of refractive index measurements as indicator of hydration; immersion refractometry with phase-contrast microscopy; and practical aspects of checking phase-change with interference microscopes. The text continues with the discussions on the Cartesian diver balance method. Particularly noted are the standards, principle, applications, and precision of the method, which has been proven effective in microgasometric measurements. The book also focuses on quantitative determination through a special ""ampulla-diver"" of the cholinesterase activity in cells. Given attention are the materials, methods, and results of experiments. The text also looks at periodate oxidation techniques; acylation and diazonium coupling in protein cytochemistry with special reference to the benzoylation-tetrazo... method; and the use of dinitrobenzene as a cytochemical reagent. The book is a great find for readers interested in studying the biochemistry of cells.

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