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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Smart Organ-on-Chip Devices

      • 1st Edition
      • April 25, 2025
      • Tiago Albertini Balbino + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 4 0 3 6
      • eBook
        9 7 8 0 4 4 3 1 3 4 0 4 3
      Smart Organ-on-Chip Devices: Dynamic Microfluidic Systems for Cell Culture discusses the concepts to engineer functional stimuli responsive organotypic-on-chip devices and its application in several fields, including drug development, disease modeling, personalized medicine, and tissue engineering. Groundbreaking studies are presented throughout the book sections to reinforce the importance of adding more reliable and robust in vitro platforms able to closely emulate the dynamism of human physiology.The authors present new information regarding in silico studies of cell spheroids within microfluidic devices, as well as step-by-step guidance on key procedures. Written for researchers, practitioners and students using microfluidic devices as platforms, by well-respected scientists from both academia and industry.

    • Cryptic Enzymes and Moonlighting Proteins

      • 1st Edition
      • April 24, 2025
      • Helen Irving + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 7 1 9 6
      • eBook
        9 7 8 0 4 4 3 1 5 7 2 0 2
      Cryptic Enzymes and Moonlighting Proteins, a new volume in the Foundations and Frontiers in Enzymology series, offers a thorough overview of cryptic enzymes and moonlighting proteins in signaling cascades. In early chapters, leading international contributors discuss evolutionary considerations for moonlighting proteins, moonlighting interactions in the extracellular matrix, eukaryotic moonlighting proteins, modulating, moonlighting kinases, moonlighting proteins in neurobiology signaling, metabolic enzymes moonlighting as RNA binding and regulatory proteins. Later, methods-driven chapters discuss practical aspects of identifying hidden moonlighting domains in proteins, computational approaches and bioinformatic tools for the identification of cryptic enzymes, establishing cryptic enzyme interactomes, and assessing contributions of moonlighting proteins to signal cascades.The book also explores recent advances in research and brings together an array of information across different fields to enable better targeting of these exciting proteins and their interactomes. With a clear focus on the role of moonlighting and cryptic enzymes in signal transduction, users will find examples of cryptic enzymes across species, as well as those in human healthy biology and pathogenesis.

    • Apobec Enzymes

      • 1st Edition
      • Volume 713
      • April 21, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 7 8 6 6
      • eBook
        9 7 8 0 4 4 3 3 1 7 8 7 3
      Apobec Enzymes, Volume 713 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Fluorescent shift assay for APOBECs RNA editing, Low Error Sequencing Methods to Detect APOBEC-mediated RNA editing: Circular RNAseq and Safe-Sequencing System, "Safe-Barcode" RNAseq assay for APOBECs RNA editing, DT40 cell system to characterize somatic hypermutation, CH12 cell system to assay AID activity on class switch recombination, Purification of Enzymatically Active APOBEC Proteins from an Insect Cell Expression System, and more.Additional chapters cover Defining genome-wide mutagenic impact of APOBEC3 enzymes, APOBEC-induced mutational assay in yeast, Assays for APOBEC drug discovery, Biochemical assay for the identification of APOBECs inhibitors, An In Vitro Cytidine Deaminase Assay to Monitor APOBEC activity on DNA, Profiling rare C-to-U editing events via direct RNA sequencing, Global quantification of off-target activity by base editors, and so much more.

    • Navigating the Complexities of SARS-CoV-2 Immunobiology

      • 1st Edition
      • Volume 213
      • April 19, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 8 3 2 1
      • eBook
        9 7 8 0 4 4 3 2 3 8 3 3 8
      Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

    • Translational Gastroenterology

      • 1st Edition
      • April 18, 2025
      • Adam E.M. Eltorai + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 4 2 6 8
      • eBook
        9 7 8 0 1 2 8 2 1 4 2 7 5
      Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.

    • Gender Affirming Vaginoplasty

      • 1st Edition
      • April 16, 2025
      • Gennaro Selvaggi + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 7 7 6 0
      • eBook
        9 7 8 0 4 4 3 2 1 7 7 7 7
      Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.

    • Whole Cell Biocatalysis

      • 1st Edition
      • April 16, 2025
      • Sergio Huerta-Ochoa + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 9 9 8 4
      • eBook
        9 7 8 0 4 4 3 2 3 9 9 9 1
      Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.

    • Chest Blunt Trauma

      • 1st Edition
      • April 16, 2025
      • Piergiorgio Solli + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 8 6 6 9
      • eBook
        9 7 8 0 4 4 3 1 3 8 6 7 6
      Chest Blunt Trauma: A Modern Approach to a Multidisciplinary Disease provides novel treatment ideas for cardiothoracic injuries. The book interweaves knowledge of new surgical techniques, better understanding of patho-physiologic effects of injuries, and enhanced intensive care methods to create a holistic strategy of patient support. This text is a welcome addition for any clinician or researcher seeking refreshed information on the management of trauma to the chest wall.While non-operative treatment has long been the standard of care, the book discusses the vast improvements in understanding how to treat cardiothoracic injuries. Innovative surgical techniques, instruments, post-operative care, and the multisystemic nature of this illness.

    • Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers

      • 1st Edition
      • April 15, 2025
      • Ankit Jain + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 9 1 2 5 8
      • eBook
        9 7 8 0 4 4 3 2 9 1 2 6 5
      Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.

    • The Potential of Cancer Biomarkers

      • 1st Edition
      • April 14, 2025
      • Pranav Kumar Prabhakar
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 2 7 9 8
      • eBook
        9 7 8 0 4 4 3 2 9 2 8 0 4
      The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.

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