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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Microbial Transformations of Steroids

      • 1st Edition
      • June 28, 2014
      • William Charney + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 0 4 3 4
      • eBook
        9 7 8 1 4 8 3 2 6 1 5 5 3
      Microbial Transformations of Steroids: A Handbook aims to provide those who wish to use microbial transformations of steroids with a single source book starting from 1937 to the present. The handbook first offers information on the history of the microbial transformations of organic compounds, including earliest works on the study of nonsteroids and steroids; significance of discovery of anti-inflammatory action of cortisone; first hydroxylations and dehydrogenations; manufacture of natural and synthetic corticosteroids; and trends in research. The text then ponders on chemical classification of microbial transformations of steroids, as well as the role of enzymes in microbial transformations and the classes of reactions. The publication elaborates on the construction and use of the table. Topics include order of the table, nomenclature, description of the transformation leading to the product, yield, organism, and constants. The book also focuses on taxonomy and use of the table, including system of classification, specific notes on divisions of the table, and source of cultures. The handbook is a valuable source of data for readers interested in the microbial transformations of steroids.

    • The Plasma Proteins

      • 1st Edition
      • May 12, 2014
      • Frank W Putnam
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 1 3 5 6
      • eBook
        9 7 8 1 4 8 3 2 5 8 6 7 6
      The Plasma Proteins, Volume I: Isolation, Characterization, and Function focuses on the reactions, properties, characteristics, and transformations of plasma proteins. The selection first offers information on the fractionation and isolation of purified components by precipitation methods and electrophoretic and ultracentrifugal analysis of normal human serum. Discussions focus on correlation of electrophoretic and ultracentrifugal results, electrophoretic analytical methodology and results, parameters influencing protein solubility, and techniques for the separation of proteins by precipitation methods. The text then ponders on the chromatography of plasma proteins and chemical composition and molecular parameters of purified plasma proteins. The manuscript elaborates on plasma albumin and macroglobulins and high molecular weight antibodies. Topics include immunological properties, physical and chemical properties of normal and pathological macroglobulins, purity, homogeneity, and variability, denaturation behavior, and sulfhydryl groups, mercaptalbumin, and the mercury dimer. The book then examines glycoproteins and metal-binding plasma proteins and cation transport. The selection is a highly recommended reference for biochemists and clinicians interested in plasma proteins.

    • Biochemistry of Glucuronic Acid

      • 1st Edition
      • May 12, 2014
      • Neal E. Artz + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 1 2 0 1 2
      • eBook
        9 7 8 1 4 8 3 2 2 5 4 4 9
      Biochemistry of Glucuronic Acid provides a comprehensive study of the metabolic importance of glucoronic acid. This book presents the physiological role of glucoronic acid as a detoxifying agent. Organized into four chapters, this book begins with an overview of the naphthoresorcinol test, which is the most accurate colorimetric method for the determination of glucoronic acid. This text then explores the occurrence of glucoronic acid, which is found in many plant gums, in oxycellulose, as well as in conjugated form in low concentrations in normal blood and urine. Other chapters consider the mechanisms for the formation of glucoronic acid in the body. The final chapter deals with detoxication as any chemical change occurring in the body that brings about the conversion of a foreign compound of known structure to a derivative that is excreted in the urine. This book is a valuable resource for biochemists.

    • Advances in Lipid Research

      • 1st Edition
      • Volume 7
      • June 28, 2014
      • Rodolfo Paoletti + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 1 8 6 3
      • eBook
        9 7 8 1 4 8 3 2 1 5 2 9 7
      Advances in Lipid Research reviews advances in lipid research and covers topics ranging from lipid histochemistry and control of plasma and liver triglyceride kinetics by carbohydrate metabolism and insulin. Lipid metabolism in tissue culture cells is also discussed, along with the carcinogenicity of steroids and the chemical and biological properties of heated and oxidized fats. Comprised of five chapters, this volume begins with an introduction to the histochemistry of lipids in both its qualitative and quantitative aspects, followed by an analysis of the roles of carbohydrate metabolism and insulin in relation to their control of the metabolism of plasma and liver triglycerides. Lipid metabolism in many tissue culture systems is the subject of the next chapter. The experimental and theoretical aspects of the connection between cancer and steroids are also examined. The last chapter deals with the possible harmful effects of heating dietary fats and how heating may alter the chemical and biological properties of fats. Attention is paid to auto-oxidation, carcinogenicity, and the interaction of heated fats with other dietary components. This monograph will be useful to students, practicing professionals, and research workers in biology and biochemistry.

    • Catecholamines and Stress

      • 1st Edition
      • May 8, 2014
      • Earl Usdin + 2 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 8 7 8 7 7
      Catecholamines and Stress covers the proceedings of the International Symposium on Catecholamines and Stress, held in Bratislava, Czechoslovakia on July 27-30, 1975. This book mainly focuses on catecholamines and stress, presenting papers specifically discussing the brain, neurohumoral regulation in stress, and changes induced by stress. A set of papers tackle the catecholamine synthesizing and degrading enzymes under stress. Other papers are devoted to topics on catecholamine synthesis and degradation under stress; release, level, and excretion of catecholamines in stress; and catecholamines and stress in man. This text will be invaluable to students and experts in physiology, biology, and related fields.

    • The Antigens

      • 1st Edition
      • May 10, 2014
      • Michael Sela
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 6 4 2 0
      • eBook
        9 7 8 1 4 8 3 2 6 9 8 9 4
      The Antigens, Volume I is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology, structure and function, their initiation of the immune response, and the nature of the products of this response. The nature of the reaction of antigens with antibodies and with sensitized cells is also explored. Comprised of seven chapters, this volume begins with a discussion on the antigenic functions of nucleic acids as well as their immunogenicity, hapten functions, and serologic reactions. The reader is then introduced to the immunochemistry and antigenic determinants of enzymes, along with the structure and phylogeny of immunoglobulins and immunoglobulin allotypes. The evolution of proteins and their structure and function is also considered, paying particular attention to evolution by the random fixation of selectively neutral alleles, the rates of protein evolution, gene duplication, and divergence or convergence. The final chapter is devoted to the chemistry and biology of immunoglobulin E as well as the regulation of formation of their antibodies. This book will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

    • Human Physiology in Extreme Environments

      • 1st Edition
      • November 26, 2014
      • Hanns-Christian Gunga
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 9 4 7 0
      • Paperback
        9 7 8 0 1 2 8 1 0 0 7 4 5
      • eBook
        9 7 8 0 1 2 3 8 6 9 9 8 2
      Human Physiology in Extreme Environments is the one publication that offers how human biology and physiology is affected by extreme environments while highlighting technological innovations that allow us to adapt and regulate environments. Covering a broad range of extreme environments, including high altitude, underwater, tropical climates, and desert and arctic climates as well as space travel, this book will include case studies for practical application. Graduate students, medical students and researchers will find Human Physiology in Extreme Environments an interesting, informative and useful resource for human physiology, environmental physiology and medical studies.

    • The Receptors

      • 1st Edition
      • May 10, 2014
      • P. Michael Conn
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 7 5 5 8
      • eBook
        9 7 8 1 4 8 3 2 7 3 6 8 6
      The Receptors, Volume II deals with receptors for somatostatin, vitamin D, insulin, and animal viruses, as well as for the ?2-adrenergic and Ah systems. The significance of translational modifications of receptor ligands is discussed, along with the mechanisms of receptor-ligand interactions. The role of receptors in development and their regulation by tumors are also considered. Comprised of 12 chapters, this volume begins with a detailed account of the vitamin D receptor, paying particular attention to its biochemical and physical properties as well as its mechanism of action. The discussion then turns to experimental discrimination between alternative mechanistic models for the receptor-mediated stimulation of adenylate cyclase; the role of microaggregation in hormone-receptor-eff... interactions; and the biology and biochemistry of the Ah receptor. Subsequent chapters explore the interactions of animal viruses with cell surface receptors; insulin receptors; determination of the size of neurotransmitter receptors by radiation inactivation-target size analysis; and protein glycosylation and receptor-ligand interactions. This book will be a valuable resource for students and practitioners in fields ranging from cell biology and biochemistry to physiology, endocrinology, and pharmacology.

    • Metabolic Activation of Polynuclear Aromatic Hydrocarbons

      • 1st Edition
      • May 9, 2014
      • Wing-Sum Tsang + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 4 3 3 5
      • eBook
        9 7 8 1 4 8 3 2 8 0 6 7 7
      Metabolic Activation of Polynuclear Aromatic Hydrocarbons deals with the metabolic activation of polynuclear aromatic hydrocarbons and covers topics ranging from the cytotoxic, mutagenic, and carcinogenic effects of arene oxides to the role of secondary metabolites as ultimate carcinogens. The mechanism of binding of metabolites derived from polynuclear hydrocarbons to key cellular sites is also discussed. This book begins with a brief review of the early work on the mechanism of chemical carcinogenesis by polynuclear hydrocarbons, followed by a detailed survey of pertinent literature in the field. The cytotoxic, mutagenic, and carcinogenic effects of arene oxides are analyzed, along with the solvolytic and nucleophilic reactions of benzo[a]pyrene (BaP) diol epoxides. The discussion then turns to the carcinogenicity, mutagenicity, and cytotoxicity of BaP metabolites; the "Bay-region" theory of carcinogenic activity and perturbational molecular orbital theory; and the mechanism of binding of metabolites derived from polynuclear hydrocarbons to key cellular sites. Research on polycyclic aromatic hydrocarbons pertaining to the "Bay-region" theory is also presented. This monograph will be of interest to chemists, biochemists, and oncologists.

    • Advances in Lipid Research

      • 1st Edition
      • Volume 18
      • June 28, 2014
      • Rodolfo Paoletti + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 1 9 7 9
      • eBook
        9 7 8 1 4 8 3 2 1 5 4 0 2
      Advances in Lipid Research, Volume 18 is a seven-chapter text that brings together significant research studies on atherosclerosis. The opening chapter describes the pathological techniques in atherosclerosis research. The succeeding chapters deal with the influence of lipid-lowering drugs on bile acid metabolism and the cholesterol metabolism in ovarian tissue. Other chapters examine the principal role of sulfolipids and the influence of dietary linoleic acids on blood pressure regulation in rats. The closing chapters review the influence of nonnutritive fiber on lipid metabolism and the influence of fiber on lipid-associated diseases. These chapters also consider the techniques for polar lipid analysis. This book will be of great value to lipid chemists, biochemists, and researchers.

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