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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Handbook of Material Biodegradation, Biodeterioration, and Biostablization

    • 3rd Edition
    • George Wypych + 2 more
    • English
    Handbook of Material Biodegradation, Biodeterioration, and Biostabilization, Third Edition provides extensive information on the microorganisms involved in the biodegradation of materials, along with the biocides which are permitted for use according to the most up-to-date worldwide legislation. The book focuses on protecting materials and products against colonization and subsequent degradation of their properties. Mechanisms of biodegradation and biodeterioration, results of biodeterioration, and methods of biostabilization are covered for a large number of products, making the title relevant for a range of industries and applications, including construction, coatings/paints, medical and pharmaceutical applications, and electronics. It also covers 13 groups of bacteria, 7 groups of fungi, and 4 groups of protozoa involved in biodegradative processes. In addition, the health and safety aspects of biocide application are covered in detail, as well as the personal protection of practitioners who are required to use them. The contents and the most-up-to-date information make this book essential for almost all the fields of applied chemistry.

  • The Cardiac Conduction System

    Evolution, Development, and Therapeutic Potential
    • 1st Edition
    • Bjarke Jensen + 1 more
    • English
    The Cardiac Conduction System: Evolution, Development, and Therapeutic Potential, the latest release in the Hot Topics in Physiology series, provides the reader a thorough and comprehensive review of this intricate system. The book covers conventional topics: anatomy, electrophysiology, and key cellular characteristics, as well as emerging topics: patient specific computer modelling, induced pluripotent stem cells, and in vivo editing as state-of-the-art treatment strategy. Given the exhaustive coverage of topics, this book is "go-to reference" for the cardiac conduction system for years to come.This volume was published in association with the International Union of Physiological Sciences (IUPS). It is an ideal reference for academics and researchers in anatomy, physiology, cardiology, electrophysiology, biomedical engineering and medical education at Undergrad, Masters, PhD, and Post-Doc levels.

  • The Resistance of Cervical Cancer to Chemotherapy and its Reversal

    • 1st Edition
    • Volume 9
    • S. Muthusami
    • English
    The Resistance of Cervical Cancer to Chemotherapy and its Reversal provides a holistic understanding of cervical cancer development, immune-evading mechanisms of HPV, immunotherapies available, methods to study cervical cancer and the development of newer drugs. Content shows the involvement of signaling pathways during chemoresistance in cervical cancer, the involvement of genes in drug resistance, and introduces long noncoding RNAs as novel biomarkers.In 10 chapters, this book first provides an introduction and history of cervical cancer; next, it discusses the influence of viruses on cervical cancer and finally, it describes therapies to overcome chemotherapy resistance in cervical cancer. This is the perfect reference to provide the fundamental base of knowledge needed for oncologists, pharmacologists, translational investigators, immunotherapists, scientists, and clinicians interested in building a comprehensive understanding of the field.

  • Mathematical Concepts and Methods in Modern Biology

    Using Modern Discrete Models
    • 2nd Edition
    • Raina Robeva
    • English
    Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models, Second Edition presents an updated, quantitative framework for analyzing, predicting, and modulating complex biological systems. Structured around project-based learning and problem-solving, it integrates essential mathematical concepts and methods in the context of key biological questions. Topics include gene regulatory and neuronal networks, CpG islands, plant population growth, interacting populations, phylogenetics, and phylogenomics. Modeling tools span discrete dynamical systems (including deterministic and stochastic Boolean networks), ordinary differential equations, projection matrices, agent-based modeling, polynomial ideals, Gröbner bases, tropical algebra, and other algebraic approaches. Computation is supported by a range of software tools, including some developed for this book, as well as open source, freely available, and proprietary platforms. Updated code examples and step-by-step instructions illustrate software use, making this a valuable resource for health professionals, scientists, researchers, and students in related fields.

  • Epigenetic Regulations in Gastrointestinal Cancers

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 1 more
    • English
    Epigenetic Regulations in Gastrointestinal Cancers offers a comprehensive exploration of the genomic and epigenomic alterations that underpin the aggressive nature of gastrointestinal (GI) cancers. . By synthesizing the latest research and insights into the role of the tumor microenvironment and cellular signaling pathways, this book aims to elucidate the multifaceted nature of GI cancer neoplasia and propose innovative therapeutic strategies. Addressing critical challenges in GI cancer research and treatment, this book serves as a vital resource for researchers and clinicians striving to bridge the gap between basic research and clinical application. It tackles the complexities of GI cancer mechanisms by integrating knowledge from diverse fields, thereby providing a holistic understanding essential for effective therapeutic development. Through real-world case studies and expert contributions, the book highlights successful treatment regimens that leverage epigenetic insights, thereby fostering dialogue among multidisciplinary teams and promoting collaborative approaches to cancer care. Moreover, the book emphasizes the importance of staying abreast of rapid advancements in the field of cancer research. With contributions from leading experts and an accompanying online platform featuring interactive resources, readers will have access to the latest insights and developments in GI cancer research. By identifying specific epigenetic targets and innovative strategies for overcoming treatment resistance, this book aspires to enhance patient outcomes in GI cancers and contribute to the ongoing evolution of personalized medicine in oncology.

  • Group B Streptococcus in Pregnancy, Childbirth, and the Neonatal Period

    • 1st Edition
    • Philip Steer + 1 more
    • English
    Group B Streptococcus (GBS) in Pregnancy, Childbirth, and the Neonatal Period brings together field experts to provide a comprehensive understanding of group B streptococcus (GBS), the most common cause of perinatal infection today. It discusses this important bacterium and infection within pregnancy, both obstetric and fetal aspects during labor, and in the infant.The book opens with a global view of GBS, recounting the history and variation in risk factors and outcomes across regions. Subsequent chapters cover not only the biology, epidemiology and pathology, but also intricately describe infection management, treatment, and prevention options. Both early onset as well as late onset GBS disease are discussed.Further, written accounts of lived experiences with varying outcomes are included, along with strategies to aid practitioners in improving care and understanding of babies and families impacted by GBS. The book concludes with clarification of common misconceptions and discussion of future directions in prevention and treatment options. This comprehensive reference offers evidence-based insights aimed at enhancing practice and ultimately improving perinatal outcomes.

  • Genetics of Bone Biology and Skeletal Disease

    • 3rd Edition
    • Rajesh V. Thakker + 3 more
    • English
    Genetics of Bone Biology and Skeletal Disease, Third Edition is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid, and related disorders, and vitamin D and renal disorders.Sections cover bone biology and structure, joint and cartilage biology, principles of endocrine regulation, the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasia, rarer bone disorders, and much more.

  • Cell Shape and Position during Development

    • 1st Edition
    • Volume 166
    • English
    Cell Shape and Position during Development, Volume 166 provides a comprehensive overview of the fundamental roles that cell morphology and spatial organization play in the development of multicellular organisms. This volume brings together leading experts in developmental biology, cell biology, and biophysics to explore how cells acquire specific shapes. Chapters in this new release include Cell shape changes during sperm-egg interactions, Cell shape and position during organ development, Regulation of shape and position during asymmetric cell division, Cell shape dynamics during mouse peri-implantation development and embryo dormancy, Shaping the intestine: the role of cell morphology and spatial dynamics in development, and more.Additional sections Intermediate filaments in cell shape and position, Regulation of adult stem cell behavior by cytoskeletal dynamics and cell shape, Shape changes in gastrulation, and more.

  • Retinoic Acids in Cancer Therapy

    Mechanisms of Sensitivity, Resistance, and Methods of Delivery
    • 1st Edition
    • Volume 23
    • Saeid Ghavami + 2 more
    • English
    Retinoic Acids in Cancer Therapy: Mechanisms of Sensitivity, Resistance, and Methods of Delivery provides an overview of how All-Trans Retinoic Acid (ATRA) kills cancer cells and how some cells survive treatment. Focusing on the cellular pathways and compartments involved in ATRA-mediated inhibition of proliferation, this book also discusses how aggressive tumors develop escape routes conferring retinoic acid resistance.Across 15 chapters, it describes the molecular structure and biological properties of ATRA, explains mechanisms of resistance, and defines ATRA’s efficacy in seven cancer types. It concludes with chapters on ATRA and cancer stem cell biology, strategies to improve treatment, future therapeutic perspectives, and delivery methods to reduce toxicity and enhance anticancer efficacy.Each chapter includes Learning Objectives and a “What We Learn” section, making the book highly accessible for undergraduate, graduate trainees, scientists, physicians, and biotech companies. Adding simple, attractive schemes and informative tables makes it ideal for all interested in the current status of Retinoic Acids in Cancer Therapy. This book serves as a valuable resource for health professionals, scientists, researchers, clinical practitioners, and all those seeking to broaden their knowledge and develop new drugs or therapeutic strategies to improve ATRA’s efficacy in the treatment of resistant cancers.

  • The Gut Microbiome in Precision Medicine

    From Research to Clinical Practice
    • 1st Edition
    • S Rehan Ahmad
    • English
    The Gut Microbiome in Precision Medicine: From Research to Clinical Practice explores the significant role of the gut microbiome in health and disease, particularly within gastrointestinal conditions such as inflammatory bowel disease, irritable bowel syndrome, and colorectal cancer. It covers how understanding and analyzing the gut microbiome can lead to personalized treatments, dietary plans, and precision medicine approaches in gastroenterology. Chapters explore multi-omics integration, examining complex techniques for gut microbiome profiling, including genomics, transcriptomics, proteomics, and metabolomics. Users will find updates on microbiome-based interventions, such as probiotics, prebiotics, and personalized nutrition that highlight practical applications in gastrointestinal disease management. Real-world examples and case studies discuss strategies for overcoming barriers to implementing microbiome analysis. Additionally, it addresses the challenges and opportunities of implementing microbiome analysis in clinical practice, with a special emphasis on its implications for developing countries. Finally, the book covers emerging technologies in microbiome research and their applications in gastroenterology, emphasizing future directions and research priorities.

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