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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Nuclear Proteins

      • 1st Edition
      • Volume 143
      • January 23, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 6 4 5
      • eBook
        9 7 8 0 4 4 3 2 9 5 6 5 2
      Advances in Protein Chemistry and Structural Biology, Volume 143 in the series, covers reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design. Chapters in this new release include Therapeutic insight into the role of nuclear protein HNF4α in liver carcinogenesis, Structural mechanism of nucleoporins in cancer disease, Identification of nuclear matrix proteins (novel genes) in bladder cancer using Bioinformatic approaches, A comparative study of nuclear proteins of different cancers - A systematic review, Role of lamins in cellular physiology and cancer, and much more.Other chapters cover Nuclear Hormone Receptors as Drug Targets: Advancements and Future Prospects, Proteins binding to tandemly repeated DNA: familiar strangers, HMGB1, R-loops and genome stability, Nuclear tau accumulation in Alzheimer's Disease, and Histone deacetylase's (HDACs) regulates Tau function in Alzheimer's Disease.
    • Encyclopedia of Bioinformatics and Computational Biology

      • 2nd Edition
      • March 25, 2025
      • Shoba Ranganathan + 2 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 5 5 0 2 7
      • eBook
        9 7 8 0 3 2 3 9 5 5 0 3 4
      Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery.In the era of molecular diagnostics, targeted drug design, translational medicine and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well as mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Artificial Intelligence, Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology, and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can help us better prepare for such future events.This Encyclopedia comprises three sections, covering Methods, Topics, and Applications. The methodologies and algorithms underpinning BCB are described in the Methods section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked “how to” questions.Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definitions of terminology and lucid explanations by field experts.
    • Recent Advances in Liver Cirrhosis Related Complications

      • 1st Edition
      • July 9, 2025
      • Xingshun Qi + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 9 3 8 2
      • eBook
        9 7 8 0 4 4 3 2 1 9 3 7 5
      Recent Advances in Liver Cirrhosis Related Complications provides comprehensive coverage on the contemporary management of liver cirrhosis related complications and future directions for the field. Content covers epidemiology, diagnosis, risk stratification, and pathophysiology. Contents include coverage of the gut microbiota, ascites, and gastrointestinal bleeding as well as the challenges of hepatic encephalopathy, acute kidney injury, bacterial infections, coagulation abnormality, and venous thromboembolism, amongst others. This is the perfect resource for practicing gastroenterologists and hepatologists as well as family physicians and investigators who are skilled at the management of liver cirrhosis and its complications.
    • Explainable AI in Healthcare Imaging for Medical Diagnoses

      • 1st Edition
      • March 29, 2025
      • Tanzila Saba + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 9 7 9 3
      • eBook
        9 7 8 0 4 4 3 2 3 9 7 8 6
      In an era where Artificial Intelligence (AI) is revolutionizing healthcare, Explainable AI in Healthcare Imaging for Precision Medicine addresses the critical need for transparency, trust, and accountability in AI-driven medical technologies. As AI becomes an integral part of clinical decision-making, especially in imaging and precision medicine, the question of how AI reaches its conclusions grows increasingly significant. This book explores how Explainable AI (XAI) is transforming healthcare by making AI systems more interpretable, reliable, and transparent, empowering clinicians and enhancing patient outcomes.Through a comprehensive examination of the latest research, real-world case studies, and expert insights, this book delves into the application of XAI in medical imaging, disease diagnosis, treatment planning, and personalized care. It discusses the technical methodologies behind XAI, the challenges and opportunities of its integration into healthcare, and the ethical and regulatory considerations that will shape the future of AI-assisted medical decisions.Key areas of focus include the role of XAI in improving diagnostic accuracy in fields such as radiology, pathology, and genomics and its potential to enhance collaboration between AI systems, healthcare professionals, and patients. The book also highlights practical applications of XAI in personalized medicine, showing how explainable models help tailor treatments to individual patients, and discusses how XAI can contribute to reducing bias and improving fairness in medical decision-making.Writ... by leading experts in AI, healthcare, and precision medicine, Explain[S3G1] able AI in Healthcare Imaging for Precision Medicine is an essential resource for researchers, clinicians, students, and policymakers. Whether you are looking to stay at the forefront of AI innovations in healthcare or seeking to understand how explainability can build trust in AI systems, this book provides the insights and knowledge needed to navigate the evolving landscape of AI in medicine. It invites readers to explore how XAI can revolutionize healthcare and precision medicine, shaping a future where AI is both powerful and trustworthy.
    • Artificial Metalloproteins

      • 1st Edition
      • Volume 720
      • October 1, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 4 1 5 7 3 9
      • eBook
        9 7 8 0 4 4 3 4 1 5 7 4 6
      Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-... Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more.Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.
    • Targeted Protein Degradation Technologies

      • 1st Edition
      • June 27, 2025
      • Jiangjiang Qin + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 8 1 6 3
      • eBook
        9 7 8 0 4 4 3 2 1 8 1 7 0
      Targeted Protein Degradation Technologies offers a comprehensive exploration of the field of targeted protein degradation, from its latest scientific advancements to its potential therapeutic applications. This book begins with a foundational introduction to the mechanisms of protein degradation, followed by an in-depth look at both protease-mediated and lysosome-mediated degradation pathways. The text delves into a range of cutting-edge technologies, including PROTAC, AbTAC, molecular glues, hydrophobic tagging, LYTAC, GlueTAC, and AUTAC. It then explores the development of degraders for specific proteins, such as signal transduction receptors, membrane proteins, and transcription factors. This book concludes with a focused discussion on the clinical applications of targeted protein degradation and provides an insight into the future directions for this field.This book serves as an invaluable resource for researchers and professionals in molecular biology, cell biology, and related disciplines, particularly those involved in protein degradation and the development of novel therapeutic strategies.
    • Protides of the BIological Fluids

      • 1st Edition
      • April 28, 2025
      • H. Peeters + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 4 7 0 0
      • eBook
        9 7 8 1 4 8 3 2 7 9 5 0 3
      An International Review Series Devoted to Proteins and Related Studies, Volume 36: Protides of the Biological Fluids documents the proceedings of the 36th Colloquium held in 1989. This book discusses the structure of the human IgA subclasses and allotypes; comparison of normal values of IgG subclasses; and structural genetic alterations in Ig subclass deficiencies. The interleukin cascade for the regulation of IgA synthesis and immune responses; phenotypic and functional changes during T cell activation; and flow cytometric analysis of sequential tumor biopsies during therapy are also elaborated. This text likewise covers the serum and fecal proteins during Crohn's disease and isolation and properties of apolipoprotein A for therapeutic use. This publication is recommended for students and specialists conducting work on the study of proteins and techniques of their isolation, purification, and immunological quantitation.
    • Revolutionizing Digital Healthcare Through Artificial Intelligence and Automation

      • 1st Edition
      • September 30, 2025
      • Alex Khang
      • English
      • Paperback
        9 7 8 0 4 4 3 3 6 4 3 4 1
      • eBook
        9 7 8 0 4 4 3 3 6 4 3 5 8
      Revolutionizing Digital Healthcare Through Artificial Intelligence and Automation: Principles, Technologies, and Applications is a transformative exploration of how Artificial Intelligence (AI) and automation technologies are reshaping the healthcare landscape. In an era where precision, efficiency, and accessibility in medical services are paramount, this book delves into cutting-edge advancements in AI-powered diagnostics, wearable smart devices, and automated patient care systems. It stands as a beacon for innovators and healthcare professionals who aim to harness technology to streamline processes, improve patient outcomes, and create sustainable solutions in an ever-evolving industry.Beyond its focus on AI and automation, the book also examines the ethical implications and challenges of integrating technology into healthcare. It discusses strategies for implementing these technologies while ensuring patient privacy, maintaining human connection in care delivery, and navigating regulatory hurdles. With detailed case studies and forward-looking insights, the text provides a comprehensive roadmap for leveraging digital tools to shape the future of healthcare.
    • Drug Delivery Landscape in Cancer Research

      • 1st Edition
      • April 3, 2025
      • Ranjita Shegokar + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 9 1 6 8 5
      • eBook
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      Drug Delivery Landscape in Cancer Research examines the combined impact of prevention, diagnosis, and treatment of cancer. With a strong focus on the status, challenges, and prospects of cancer drug delivery technology, the book examines clinical translation-related knowledge and the development of different organ related cancers. In 22 chapters, it describes current and new drug delivery systems in twenty different cancers and gives insights into drug delivery strategies and tumor microenvironment management in oral and ocular cancers. This book is a timely and valuable resource for health professionals, scientists, researchers, health practitioners, students, and anyone who wants to broaden their knowledge.
    • Biomedical and Clinical Cryogenics

      • 1st Edition
      • April 4, 2025
      • Hussam Jouhara + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 3 0 1 1 8 6
      • eBook
        9 7 8 0 4 4 3 3 0 1 1 9 3
      Biomedical and Clinical Cryogenics: Theory, Current Technology Advances, and Future Perspectives presents the complexity of cryogenic engineering applications in both medical and clinical settings. The book demonstrates both a comprehensive and up-to-date understanding of ongoing, new applications and their cutting-edge breakthroughs within the biomedical engineering sector. It contributes to the rapidly emerging and expanding field of cryogenics by emphasizing the complexity of associated mechanisms and interactions. In six chapters, this book collects, investigates, and critically discusses state-of-the-art cryogenic practices, along with the challenges and perspectives of the most common applications.By using cryogenics sciences, new milestones in medicine and human-life expectancy can be significantly increased. Since this is highly interdisciplinary content, this book is a valuable resource for biomedical engineers, health professionals, scientists, researchers, students, and all those who wish to broaden their knowledge in the allied field.