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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Molecular Diagnostics and Treatment of Pancreatic Cancer

      • 1st Edition
      • April 14, 2014
      • Asfar Azmi
      • English
      • Paperback
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      Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted. Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design.
    • The Biochemistry of Development

      • 1st Edition
      • May 17, 2014
      • Jean Brachet
      • P. Alexander + 1 more
      • English
      • Paperback
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      The Biochemistry of Development focuses on advances in chemical embryology. The book first discusses gametogenesis, including the processes of oogenesis and spermatogenesis. The text describes fertilization and related aspects, such as physical, morphological, and metabolic changes during fertilization. The selection also underscores the process of cleavage. Concerns include morphology and cytochemistry of dividing eggs; importance of nucleic acids and proteins; formation of the furrow; and biochemistry of cleavage. The text also looks at the chemical embryology of invertebrate eggs. Examinations are done on the eggs of worms, mollusks, sea urchins, and ascidians. The book also evaluates the chemical embryology of vertebrate eggs. RNA and protein metabolism of intact eggs; chemical nature of inducing substances; and physical properties of inducing agents are underscored. The text also offers information on the biochemistry of differentiation and the biochemical interactions between the nucleus and the cytoplasm during morphogenesis. The selection is highly recommended for readers wanting to study chemical embryology.
    • Clinical Biochemistry of Domestic Animals

      • 3rd Edition
      • June 28, 2014
      • Jiro J. Kaneko
      • English
      • eBook
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      Clinical Biochemistry of Domestic Animals, Third Edition, represents a major revision of the previous editions. Since the publication of the first edition of ""Clinical Biochemistry of Domestic Animals,"" veterinary clinical biochemistry has enjoyed a virtual explosion of new knowledge commensurate with the increased importance of companion animals, the livestock industry, and experimental animals. This third edition brings together some of the most important areas of clinical biochemistry pertinent to these sectors. For this purpose, new chapters on the reproductive hormones and clinical enzymology have been added, in addition to a rewriting of the chapters on renal function and plasma proteins and extensive revisions of all other chapters. The volume contains 18 chapters and opens with discussions of carbohydrate and lipid metabolism and associated disorders. This is followed by separate chapters on serum proteins and the dysproteinemias; porpyhrins; clinical enzymology; liver, pancreatic, and kidney function; and the physiology and pathophysiology of body fluids. Subsequent chapters deal with pituitary, adrenal, and thyroid function; skeletal muscle function; calcium, phosphorus, magnesium, and iron metabolism; the mechanisms of homeostasis; and cerebrospinal fluid physiology.
    • Stem Cells

      • 2nd Edition
      • May 23, 2014
      • Christine L. Mummery + 3 more
      • English
      • Paperback
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      The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies.
    • Cellular Endocrinology in Health and Disease

      • 1st Edition
      • February 12, 2014
      • Alfredo Ulloa-Aguirre + 1 more
      • English
      • Hardback
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      Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. Among these are those whose function was not obvious until recently, including the endocrine functions of bone and the adipose tissue. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and P. Michael Conn, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts.
    • Techniques in Protein Chemistry

      • 1st Edition
      • June 28, 2014
      • John W. Crabb
      • English
      • eBook
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      Techniques in Protein Chemistry V highlights current methods in peptide and protein mass spectrometry, sequence and amino acid analysis, fragmentations, separations, protein folding and modeling, peptide and protein NMR, and peptide synthesis. This volume emerged from the manuscripts presented at the Seventh Symposium of the Protein Society, held in San Diego on July 24-28, 1993. This volume is organized into eight parts encompassing 61 chapters. The first part surveys the peptide and protein characterization, detection, and analysis by mass spectrometry. The subsequent parts describe the structural characterization and analysis of posttranslational processing events, as well as the characterization of protein and amino acid sequences using several analytical techniques. Other parts explore other analytical methods for peptide and protein separations; some aspects involved in protein design and functional domain analysis; and the evaluation of protein conformation, folding, and modeling. The last parts contain research papers on NMR analysis of peptide and protein solution structures. These parts also look into topics related to peptide synthesis and peptide libraries. This book is intended primarily for protein and analytical chemists.
    • Biomolecular Electronics

      • 1st Edition
      • April 3, 2014
      • Paolo Facci
      • English
      • Hardback
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      Biomolecular Electronics – the electrical control of biological phenomena – is a scientific challenge that, once fully realized, will find a wide range of applications from electronics and computing to medicine and therapeutic techniques.This new arena of biomolecular electronics is approached using familiar concepts from many areas such as electrochemistry, device electronics and some mechanisms of gene expression level control. Practical techniques are explored by which electrical and electronic means can be used to control biological reactions and processes. Also, the current and future applications for this new and expanding field are discussed.This book is aimed at scientists and engineers involved in both research and commercial applications across fields including bioelectronics, bionanotechnology, electrochemistry and nanomedicine – providing a state-of-the-art survey of what's going on at the boundary between biology and electronic technology at the micro- and nano- scales, along with a suggestive insight into future possible developments.
    • Advances in Lipid Research

      • 1st Edition
      • Volume 4
      • November 25, 2014
      • Rodolfo Paoletti + 1 more
      • English
      • Paperback
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      Advances in Lipid Research, Volume 4 provides information pertinent to the actions of catecholamines to lipid metabolism. This book discusses lipid metabolism in microorganisms wherein one relates specifically to the fatty acids of microorganisms and the other to general aspects of lipid metabolism in microorganisms. Organized into seven chapters, this volume begins with an overview of some of the contributions of lipid research to the understanding of the clotting mechanism. This text then examines the extent to which dietary carbohydrate interferes in lipid metabolism. Other chapters consider the lipid-mobilizing effects of adrenomimetic agents, which are highly specific for the depot type of adipose tissue. This book discusses as well a number of areas of bacterial lipid biochemistry that are under investigation. The final chapter deals with the procedures for assessing the purity of labeled lipids by organic synthesis, biosynthesis, and isotope exchange techniques. This book is a valuable resource for biochemists, scientists, and research workers.
    • Structure and Function of Biological Membranes

      • 1st Edition
      • June 28, 2014
      • Lawrence I. Rothfield
      • English
      • Paperback
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      Structure and Function of Biological Membranes explains the membrane phenomena at the molecular level through the use of biochemical and biophysical approaches. The book is an in-depth study of the structure and function of membranes. It is divided into three main parts. The first part provides an overview of the study of the biological membrane at the molecular level. Part II focuses on the detailed description of the overall molecular organization of membranes. The third part covers the relationship of the molecular organization of membranes to specific membrane functions; discusses catalytic membrane proteins; presents the role of membranes in important cellular functions; and looks at the membrane systems in eukaryotic cells. Biochemists, cell physiologists, biologists, researchers, and graduate and postdoctoral students in the field of biology will find the text a good reference material.
    • Disorders of Mineral Metabolism

      • 1st Edition
      • May 10, 2014
      • Jack W. Coburn + 1 more
      • English
      • Paperback
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      Disorders of Mineral Metabolism, Volume II: Calcium Physiology is a nine-chapter text that deals with the normal function of calcium, with much emphasis on a host of intracellular functions. This volume discusses the calcium absorption, excretion, and homeostasis, as well as the hormonal modifiers of its metabolism. The role of connective tissue and bone, the major storehouse of body calcium, is reviewed in terms of collagen metabolism. This book will prove useful to biochemists, pathophysiologists, and workers in the medical field.