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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Epigenetic Shaping of Sociosexual Interactions: From Plants to Humans

      • 1st Edition
      • Volume 86
      • August 20, 2014
      • English
      • Hardback
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      Epigenetic Shaping of Sociosexual Interactions: From Plants to Humans is the first attempt to interpret the higher social functions of organisms. This volume covers an extraordinarily wide range of biological research and provides a novel framework for understanding human-specific brain functions.
    • Biomolecular Modelling and Simulations

      • 1st Edition
      • Volume 96
      • September 30, 2014
      • English
      • Hardback
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      Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.
    • Protides of the Biological Fluids

      • 1st Edition
      • May 18, 2014
      • H. Peeters
      • English
      • eBook
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      Protides of the Biological Fluids contains the proceedings of the XXIVth Colloquium on Protides of the Biological Fluids held in Brugge, Belgium in 1976. Contributors explore relevant findings about protides of biological fluids and discuss topics such as pregnancy-associated proteins, carcino-fetal and carcinoplacental proteins, and molecular amplification. This volume consists of 151 chapters organized into three sections and begins with a discussion of the problems of specific placental and fetal proteins as well as the appearance of these proteins in maternal serum. The biochemistry and structure of human placental lactogen is considered together with its possible application in the diagnosis of abnormal pregnancy and the role of pregnancy specific proteins especially with regard to immunization during pregnancy. The next section focuses on oncofetal proteins, with particular reference to the biological significance of alpha-fetoprotein, its appearance during various types of cancer, and its increase in abnormal pregnancy. The isolation and properties of CEA and related antigens such as TPA, and the importance of their assay in early cancer detection as well as in follow-up studies of patients after surgery or therapy are described. The final section explores the use of molecular amplification in detection of trace amounts of proteins. It explains how radio-immunoassay, RIA, or ELISA can amplify a basic reaction between two molecules and increase its specificity as well as its limits of detection. This book will be of interest to scientists, students, and researchers working in the fields of biology and biochemistry.
    • Cell-wide Metabolic Alterations Associated with Malignancy

      • 1st Edition
      • Volume 543
      • June 7, 2014
      • English
      • Hardback
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      • eBook
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      This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.
    • The Structure and Function of Muscle V4

      • 2nd Edition
      • April 24, 2014
      • Geoffrey Bourne
      • English
      • Paperback
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      The Structure and Function of Muscle discusses relevant issues that directly affect both the structure and function of the muscular system. These issues are approached from different perspectives, such as biochemical and molecular. This book discusses several factors that can affect the condition and performance of the muscular system, both externally (parasitic and viral infections, nutritional deficiency, drugs) and internally (genetics and muscular degeneration). It also presents several types of myopathies and their distinctive traits compared to other diseases with similar symptoms. This text contains relevant information about the causes and effects of the afflictions of the muscular system. Students, medical practitioners, and researchers specializing in mycology will find this book invaluable.
    • Lymphokines

      • 1st Edition
      • June 5, 2014
      • Edgar Pick
      • English
      • Paperback
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      Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycyt... acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.
    • The Central Nervous System Control of Respiration

      • 1st Edition
      • Volume 209
      • April 17, 2014
      • English
      • Hardback
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      Respiration is one of the most basic motor activities crucial for survival of the individual. It is under total control of the central nervous system, which adjusts respiratory depth and frequency depending on the circumstances the individual finds itself. For this reason this volume not only reviews the basic control systems of respiration, located in the caudal brainstem, but also the higher brain regions, that change depth and frequency of respiration. Scientific knowledge of these systems is crucial for understanding the problems in the many patients suffering from respiratory failure.
    • Reconstituting the Cytoskeleton

      • 1st Edition
      • Volume 540
      • March 11, 2014
      • English
      • Hardback
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      • eBook
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      This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cytoskeletal structure, including such topics as rotational movement of formins studied by fluorescence polarization microscopy, in vitro assembly assays for bacterial actin filaments, and modulators of microtubule plus end growth.
    • Advances in Planar Lipid Bilayers and Liposomes

      • 1st Edition
      • Volume 20
      • July 15, 2014
      • English
      • Hardback
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      Although the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the "Advances in Planar Lipid Bilayers and Liposomes’ (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes, controlled release of functional molecules, drug delivery to cancer cells, pharmaceutical formulations to food products, the applications are simply enormous. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.
    • Progress in Lipid Research

      • 1st Edition
      • May 9, 2014
      • Ralph T. Holman
      • English
      • Paperback
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      Progress in Lipid Research, Volume 18 focuses on the advancements of processes, methodologies, and approaches involved in lipid research. The selection first elaborates on lipid composition of marine and estuarine invertebrates; role of acylcoenzyme A: cholesterol O-acyltransferase in cholesterol metabolism; and synthesis of acyl lipids in plant tissues. Discussions focus on fatty acid synthesis, turnover of complex lipids, arterial wall and atherosclerosis, cholesteryl ester metabolism, and solubilization. The text then examines the effects of ethanol ingestion on lipid metabolism, including fatty acid oxidation and ketogenesis, lipid peroxidation, plasma triacylglycerols and lipoproteins, phospholipid metabolism, and cholesterol and bile acids. The publication takes a look at lipid metabolism in liver and selected tissues and in the whole body of ruminant animals and the effect of caval shunts on lipid metabolism. Topics include adaptation and regulation of lipid metabolism in the whole animal, lipid metabolism in specific tissues, and the effects of caval shunts on tissue lipids. The text also ponders on lipid metabolism in the neonatal ruminant, as well as transfer of lipids across the placenta, maternal contribution to fetal lipid requirements, and placental lipid metabolism. The selection is a dependable source of data for readers interested in lipid research.