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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Alternative Splicing

    Recent Advances in Health and Disease
    • 1st Edition
    • Sayeed ur Rehman A. Kalam + 1 more
    • English
    Alternative Splicing: Recent Advances in Health and Disease offers a comprehensive study of this cellular process, its fundamental characteristics, latest advances, and clinical utilization. Opening with an introduction to alternative splicing and its function in generating transcriptome and protein diversity, the book considers the role of this process across a range of diseases and disorders, including cardiovascular disease, cancer, obesity, and viral infections. Key methods used to study alternative splicing are also investigated, including high-throughput sequencing-based methods, bioinformatics tools, computational methods, single-cell sequencing techniques and mass-spectrometry based proteomics.This is followed with analysis of therapeutic approaches associated with alternative splicing. This is an ideal reference for those involved in investigating alternative splicing and its impact to health and disease, and is therefore relevant to researchers across cell biology, molecular biology, pharmacology and related areas.

  • Imaging of Foreign Bodies, Aesthetic Implants, and Mal-Positioned Medical Devices in Humans

    • 1st Edition
    • Ajay K. Singh
    • English
    Imaging of Foreign Bodies, Aesthetic Implants, and Mal-Positioned Medical Devices in Humans offers an essential resource for radiologists, surgeons, emergency physicians, and related specialists involved in diagnosing and managing foreign bodies and medical device complications. This reference addresses the growing complexity of foreign body detection across diverse anatomical regions, emphasizing the need for precise imaging protocols and interpretation skills. It systematically covers the full spectrum of clinical presentations, from ingested and aspirated objects to iatrogenic and traumatic foreign bodies, integrating advanced imaging modalities such as plain radiography, CT—including innovative techniques like dual-energy CT—MRI, and ultrasound. The content is structured into detailed chapters, each providing insights into typical imaging signs, modality-specific advantages and limitations, and management strategies tailored to complex cases. The book aims to enhance diagnostic accuracy, reduce uncertainty, and facilitate prompt, appropriate intervention, ultimately improving patient outcomes. Its comprehensive scope and focus on emerging imaging technologies make it an indispensable tool for clinicians facing daily challenges in foreign body detection and management, as well as for researchers and educators seeking a current, authoritative reference.

  • Introduction to Structural Bioinformatics

    • 1st Edition
    • Yang Zhang + 2 more
    • English
    Introduction to Structural Bioinformatics offers a complete overview on the fundamental concepts and methodologies of structural bioinformatics and computational structural biology. The book is divided into three sections, beginning with a discussion of the key principles of bioinformatics and fundamental aspects, including bioinformatics databases, multiple sequence alignment, and machine learning. Section two then moves on to structural bioinformatics, where topics include Monte Carlo simulation, protein structure prediction, RNA structure prediction, and protein design. The final section of the book focuses on experimental structural determination, where chapters focus on techniques including X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy. This is an ideal guide on key principles, methods, and the most up-to-date developments across structural bioinformatics and computational structural biology. It will be a comprehensive reference for postgraduate students, instructors, and researchers working in these and adjacent subjects.

  • Multiple Faces of Takotsubo Syndrome

    Clinical Presentations, Mechanisms and Advanced Diagnostic Insights
    • 1st Edition
    • Luca Saba + 1 more
    • English
    Multiple Faces of Takotsubo Syndrome: Clinical Presentations, Mechanisms and Advanced Diagnostic Insights offers a thorough review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. The book begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. Then, clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement.A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. The book offers invaluable benefits to scientists, researchers, and clinicians alike.

  • Management of Chronic Kidney Disease and Its Complications

    • 1st Edition
    • Thakur Gurjeet Singh + 4 more
    • English
    Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.Management of Chronic Kidney Disease and Its Complications is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.

  • Prokineticins

    From the Gastrointestinal Tract to Neuroinflammation
    • 1st Edition
    • Roberta Lattanzi + 1 more
    • English
    Prokineticins: From the Gastrointestinal Tract to Neuroinflammation explores the intricate biology and pathophysiological roles of prokineticin peptides, from developmental processes in the heart and brain to the regulation of homeostasis in health and disease. Beginning with an introduction to prokineticins, the book moves on to discuss physiological functions across the human body, including the regulation of circadian rhythm, food intake, heart and kidney function and the reproductive system. Chapters then cover the prokineticin system in neurogenesis dysfunction, obesity and diabetes, reproductive system disorders and cardiovascular diseases.The prokinetcin system is also explored in the context of neurodegenerative disease and traumatic brain injury, pain, inflammation, infection and cancer. It also investigates natural and pharmacological inhibitors of PK receptors and closes with a look towards future research perspectives.

  • Wound Microenvironment Responsive Smart Dressing for Effective Healing

    • 1st Edition
    • Mohit Kumar + 4 more
    • English
    Wound Microenvironment Responsive Smart Dressing for Effective Healing presents a cutting-edge scientific exploration of phytoconstituent-bas... smart wound dressings engineered to accelerate and improve tissue repair. Bridging the therapeutic wisdom of traditional herbal medicine with advanced biomaterials, nanotechnology, polymer science, and bioengineering, this volume highlights how natural bioactive compounds can be transformed into clinically viable wound therapies. The book provides an integrated understanding of the molecular and cellular mechanisms governing wound healing, and demonstrates how stimuli-responsive delivery platforms—sensitive to pH, temperature, enzymes, ROS, or glucose—can enable precise, controlled release of phytochemicals directly at the wound site. These innovative systems overcome limitations of conventional formulations, such as instability, poor solubility, low bioavailability, and lack of targeted action. With contributions spanning smart hydrogels, nanocarriers, microneedles, 3D/4D printing, and AI-assisted wound monitoring, this multidisciplinary reference offers both foundational principles and translational guidance. Case studies and globally inclusive perspectives ensure broad relevance for researchers, clinicians, and formulation scientists working toward next-generation wound management solutions.

  • Pheochromocytoma, Paraganglioma and Adrenocortical Carcinoma: Physiopathology and Diagnosis

    • 1st Edition
    • Volume 133
    • English
    Volume 133 provides a comprehensive and up-to-date overview of three of the most challenging endocrine neoplasms—pheochromo... paraganglioma, and adrenocortical carcinoma. Bringing together contributions from internationally recognized experts, this volume explores the latest advances in tumor biology, genetics, molecular mechanisms, and endocrine pathophysiology, while offering a practical approach to modern diagnostic strategies. Readers will find detailed discussions on hereditary syndromes, genotype–phenotype correlations, biochemical testing, imaging modalities, histopathological assessment, molecular profiling, and emerging biomarkers that are reshaping the diagnosis and risk stratification of adrenal tumors. Integrating cutting-edge scientific discoveries with clinical practice, this volume serves as an essential resource for endocrinologists, oncologists, endocrine surgeons, pathologists, radiologists, nuclear medicine specialists, geneticists, researchers, and trainees seeking to improve the diagnosis and understanding of these rare but clinically significant endocrine malignancies. With its multidisciplinary perspective and strong translational focus, Volume 133 is an indispensable reference for clinicians and scientists dedicated to advancing adrenal tumor care and research.

  • Protein Misfolding

    • 1st Edition
    • Timir Tripathi
    • English
    Protein Misfolding explores the structural and biochemical foundations of protein misfolding, highlighting its wide-reaching implications for cellular function, disease progression, and biomedical innovation. This book provides a comprehensive understanding of how proteins deviate from their native conformations and the resulting biological consequences. Focusing on both physiological and pathological misfolding, the volume covers essential topics such as folding quality control, molecular chaperones, degradation pathways, and proteostasis. It presents in-depth analyses of protein aggregation mechanisms, amyloid formation, and misfolding-associate... diseases including Alzheimer's, Parkinson's, and prion-related disorders. Additional chapters explore structural approaches to understanding misfolded states, computational modeling of aggregation kinetics, and current efforts to design therapeutics that restore folding homeostasis or prevent toxic accumulation. The book also addresses the cellular response to misfolding stress and the integration of folding dynamics with cellular signaling pathways.This book is a valuable resource for researchers, educators, and professionals in biochemistry, structural biology, molecular medicine, biotechnology, and related disciplines. It supports efforts to understand the fundamental principles of protein structure and function, while offering insight into emerging therapeutic strategies and future research directions in disease-focused protein science.

  • Federated Quantum Convolutional Neural Networks in Healthcare

    Enhancing Privacy and Efficiency
    • 1st Edition
    • Abhishek Kumar + 3 more
    • English
    Federated Quantum Convolutional Neural Networks in Healthcare: Enhancing Privacy and Efficiency explores the innovative intersection of quantum computing and federated learning in the context of healthcare. As medical data grows exponentially and privacy concerns intensify, this book addresses the urgent need for secure, scalable AI solutions that enable collaborative data analysis without compromising patient confidentiality. It offers a detailed examination of the theoretical foundations of quantum machine learning and federated systems, complemented by practical case studies spanning medical imaging, genomics, and disease diagnosis. The content delves into architecture design, security protocols, and optimization techniques, equipping researchers and practitioners with the tools to develop privacy-preserving AI models tailored for medical applications. The book also discusses regulatory considerations, deployment challenges, and future research directions, positioning itself as a vital resource for advancing healthcare AI. Its comprehensive approach bridges fundamental science and real-world implementation, empowering healthcare professionals, data scientists, and policy makers to harness next-generation quantum federated systems for improved patient outcomes and data security. This resource is essential for those seeking to implement cutting-edge AI technologies in healthcare, ensuring secure, efficient, and collaborative medical data analysis.

  • Agentic AI for Healthcare 5.0

    Intelligent Agents, Autonomous Systems, and Governance Frameworks
    • 1st Edition
    • Ondrej Krejcar + 5 more
    • English
    Agentic AI for Healthcare 5.0: Intelligent Agents, Autonomous Systems, and Governance Frameworks is an edited volume that examines how autonomous agents reshape healthcare toward Healthcare 5.0. It integrates foundations, clinical and operational applications, and governance concerns to provide a cohesive, practitioner-informe... perspective. The book covers foundational agentic models, decision-making, and cyber-physical infrastructures; it then presents application-focused chapters on autonomous clinical decision support, patient monitoring, medical robotics, and hospital workflow orchestration, followed by chapters on distributed learning, semantic interoperability, digital twins, and cybersecurity. For researchers in bioinformatics, clinicians, and policymakers, it clarifies when and how agentic AI adds value, supports safe deployment, and informs governance. It equips readers with evaluation frameworks, design patterns, and policy guidance to advance responsible adoption of intelligent agents in Healthcare 5.0.

  • Nanofibers in Cancer Management

    Therapeutic Delivery Perspectives
    • 1st Edition
    • Bhupendra G. Prajapati + 1 more
    • English
    Nanofibers in Cancer Management: Therapeutic Delivery Perspectives provides an authoritative academic resource on the role of nanofibers in advancing cancer therapy. It consolidates fundamental principles and translational strategies to address limitations of conventional treatments. The book explores polymer chemistry, fabrication techniques, and smart nanofiber systems tailored for major cancers, including breast, lung, liver, colorectal, prostate, pancreatic, ovarian, melanoma, oral, and CNS tumors. It emphasizes drug encapsulation, sustained release, localized delivery, and regulatory considerations, supported by evidence-based insights and global expertise. Readers benefit from a structured, modular approach that bridges material science and clinical application. This resource equips researchers, clinicians, and graduate students with practical knowledge to innovate targeted therapies and overcome challenges such as multidrug resistance and systemic toxicity.

  • Biology

    A Human Health Perspective
    • 1st Edition
    • Harry E. Peery + 2 more
    • English
    Biology: A Human Health Perspective offers important medical case histories and complex color illustrations, interacts with the reader, and asks questions throughout. Sections cover the basic chemistry of biology and cell origins, and energy and protein processing before discussing cell reproduction, genetics, evolution, and their place in public healthcare. Clinical applications and medical terminology are also included across chapters, and pioneering medical developments such as holographic surgery, robotic neurosurgery, and tractography are featured.This textbook, along with supporting ancillary materials such as PowerPoint slides, solution manuals and quiz banks is a vital resource for all undergraduate students studying biology or for those looking to develop a career in a health profession who need a basic understanding of the field.

  • Tissue Organization in Development

    • 1st Edition
    • Volume 171
    • English
    Tissue Organization in Development explores how cells coordinate, communicate, and arrange themselves to build functional tissues during embryonic and postnatal development. The book brings together current perspectives on the molecular, cellular, and mechanical principles that govern tissue patterning, morphogenesis, and structural organization across developing systems. Covering key topics such as cell fate specification, cell–cell interactions, extracellular matrix dynamics, polarity, migration, and tissue remodeling, it highlights how complex biological form emerges from coordinated developmental processes. This volume provides a valuable resource for researchers, students, and professionals interested in developmental biology, cell biology, and tissue formation.

  • Machine Learning in Enzymology

    • 1st Edition
    • Volume 742
    • English
    This volume surveys cutting-edge machine learning–based approaches for the study of enzyme catalysis, dynamics, and design. It brings together computational and experimental approaches that integrate molecular simulation, machine learning, and high-throughput data to interrogate enzymatic catalysis at multiple scales. The chapters in the volume highlight how data-driven frameworks complement physics-based models to advance mechanistic understanding and enable rational enzyme engineering.

  • Omics Approaches in Rhizosphere Microbiology: Part A

    • 1st Edition
    • Volume 60
    • English
    Omics Approaches in Rhizosphere Microbiology: Part A series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Hyperspectral Imaging

    • 2nd Edition
    • Jose Manuel Amigo + 1 more
    • English
    Hyperspectral Imaging, Second Edition builds on the foundational insights of the first edition, covering core analytical frameworks and introducing new algorithms, hardware technologies, and cutting-edge applications. By incorporating the latest research findings and case studies, sections provide readers with enhanced tools and techniques for effective hyperspectral and multispectral image analysis across diverse scientific, industrial, and field domains. The book also addresses evolving challenges and fresh opportunities in the field, ensuring that users are equipped with the most current knowledge and practices. It underscores the continued relevance and transformative potential of hyperspectral and multispectral imaging in contemporary research and industry.Graduate students, academics, early researchers, and industry scientists across various disciplines working with hyperspectral and multispectral images, including analytical chemistry, remote sensing, vegetation and crops, food and feed production, forensic sciences, biochemistry, medical imaging, pharmaceutical production, art studies, cultural heritage, and more will find this update extremely useful.

  • Glial Mechanisms in Sleep and Circadian Biology

    • 1st Edition
    • Marcos G. Frank
    • English
    Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep.Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

  • The Role of Machine Learning and Artificial Intelligence in Revolutionizing Healthcare

    • 1st Edition
    • Prashant Kesharwani + 1 more
    • English
    Revolutionizing Healthcare: The Role of Machine Learning and Artificial Intelligence describes the complexity of healthcare data that necessitates the expanding use of artificial intelligence (AI). This book offers an explicit accounting of vital aspects on artificial intelligence in healthcare, discussing perspectives of the technologies explored based on findings outlined in highly organized tables, illustrative figures, and flow charts. It brings together novel applications of artificial intelligence in healthcare and helps readers define major gaps in knowledge that can lead to significant scientific discoveries.In addition, the book covers computational drug design, genomic data mining, nanomedicines, medical devices, cosmeceuticals, biosensors, genome counseling, quality control, clinical trials, and cybersecurity. Researchers, students, and scientists will find the book provides foundational and practical knowledge, along with the most advanced AI applications in healthcare.

  • Biosimilars in Cancer

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Biosimilars in Cancer is a comprehensive resource on the role of biosimilars in treating various cancer types. The book offers a succinct yet thorough overview of current trends in oncology, covering 21 different cancers from liver to breast cancer. Chapters provide detailed insights into trends, fundamental facts, and practical and clinical data, making it an invaluable tool for academics and practitioners. The book empowers researchers and clinicians to enhance understanding and improve patient outcomes through the effective use of biosimilars in oncology. Targeted primarily at pharmaceutical researchers, biomedical scientists, and clinicians, it supports the growing oncology biosimilars market.In addition, the book provides critical insights for those involved in cancer diagnostics and clinical trials, helping them stay ahead in this rapidly progressing field.

  • Health Geography

    Theories, Methods, and Case Studies
    • 1st Edition
    • Peng Jia
    • English
    Health Geography: Theories, Methods, and Case Studies examines the interdisciplinary domain of health geography, systematically integrating geographical science with public health paradigms. The book provides an in-depth analysis of the theoretical foundations, methodological innovations, and practical implications of health geography. Special emphasis is placed on employing geo-spatial technologies, such as Geographic Information Systems (GIS) and remote sensing to enhance disease prevention, health risk assessments, and healthcare resource allocation.By fostering an integrative dialogue among geography, epidemiology, and advanced technological approaches, the book addresses contemporary public health challenges from local to global scales. The book includes over 50 international case studies addressing infectious and chronic diseases, and health resource allocation.

  • Artificial Intelligence (AI) in Cancer Biology

    Advancements in Diagnosis and Treatment
    • 1st Edition
    • Sadhna Aggarwal
    • English
    Artificial Intelligence (AI) in Cancer Biology: Advancements in Diagnosis and Treatment explores the revolutionary impact of AI on cancer biology and oncology. This comprehensive volume delves into AI technologies, including machine learning and deep learning, enhancing our ability to understand, diagnose, and treat cancer with unprecedented precision. The book covers a wide range of topics, from cancer biology fundamentals to AI-driven techniques in diagnosis and personalised treatment. It discusses medical imaging, genomics, drug discovery, and predictive modelling, along with ethical and regulatory considerations, offering a holistic view of AI in cancer research. For academic audiences, this book provides invaluable insights into improving clinical outcomes and patient care. Researchers and clinicians will benefit from the detailed analysis of AI applications, while students and scholars will find a wealth of information to support their studies and future innovations in cancer treatment.

  • Human-AI-Cognitive Intelligence Software, System, and Services for Quality Assurance

    Theories and Methods with Systems Thinking for Behaviour Change in the Medical Decision-Making Pathway
    • 1st Edition
    • Pantea Keikhosrokiani
    • English
    Habit-based Behavior Change Medical Information Support System and Artificial Intelligence: Theories, Methods, and Data Analytics Approach provides a guideline to design and implement Habit-based Behavior Change Support Systems (HBCSS) which can change patient’s unhealthy habits to prevent the development of diseases. It presents theories, methods, management, and data analytics approach required to design, implement, and prescribe the use of HBCSS for several diseases’ management.It discusses topics such as theories of behavior change, ontologies and knowledge management, data mining, privacy and security, descriptive and prescription analytics. In addition, it discusses how to measure habit-change, future directions of the field, and case studies based on real-world examples.It is a valuable resource for clinicians, researchers, students, and member of the biomedical and medical fields who want to learn more about the use of medical systems to improve patients’ health.

  • Fluid Dynamics of Viral Transmission

    • 1st Edition
    • Mehrzad Shams + 1 more
    • English
    Fluid Dynamics of Viral Transmission is an essential exploration into the transmission dynamics of COVID-19, focusing specifically on the airborne spread of respiratory aerosols carrying infectious viruses. In light of the recent global pandemic, it offers crucial insights into the complex interaction between fluid dynamics and viral transmission and provides practical solutions for minimizing risks in indoor environments. The book delves into CFD simulations, optimizing ventilation systems, air filtration strategies, and spatial layout modifications. It evaluates mitigation measures such as mask-wearing, physical distancing, and occupancy limits, aiming to equip readers with the knowledge to create safer indoor spaces. This book is ideal for public health officials, policymakers, healthcare professionals, engineers, researchers, and academics in fluid mechanics, computational fluid dynamics, epidemiology, and virology.

  • On Human Nature

    Biology, Psychology, Ethics, Politics, and Religion
    • 2nd Edition
    • Michel Tibayrenc
    • English
    On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human biological and cultural diversity and its adaptative significance through an extensive selection of representative chapters. Edited by renowned expert Michel Tibayrenc, this second edition features updates to all major sections of the first edition and brings novel chapters covering critical advancements in human biology, psychology, behavior, ethics, and culture. It is accessible not only to specialists, but also to students, professors, industry professionals, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.The book brings together specialists from various fields, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. A globally diverse and interdisciplinary team of experts has been carefully selected to cover the breadth of topics enclosed.

  • Translational Medicine in Dry Eye Disease

    A Comprehensive Clinical and Scientific Strategy
    • 1st Edition
    • Marco Zeppieri + 2 more
    • English
    Translational Medicine in Dry Eye Disease: A Comprehensive Clinical and Scientific Strategy offers clinicians, researchers, and healthcare professionals a comprehensive, multidisciplinary resource that translates the latest scientific advances into practical strategies for diagnosing, managing, and treating dry eye disease. By bridging laboratory research and clinical application, this book equips end users with up-to-date insights, innovative diagnostic tools, and evidence-based therapies to improve patient outcomes in the rapidly evolving field of ocular surface health.

  • Proteomics and Metabolomics in Drug Discovery

    • 1st Edition
    • Volume 155
    • English
    Proteomics and Metabolomics in Drug Discovery explores how large-scale protein and metabolite analysis is transforming the identification, validation, and development of new therapeutic targets. The book highlights emerging technologies, analytical strategies, and real-world applications that support biomarker discovery, mechanism-of-action studies, and precision medicine approaches in modern drug development.

  • Morbidity Prevention in Aging

    The Role of Salutogenesis Amidst Crises
    • 1st Edition
    • Nestor Asiamah + 3 more
    • English
    Morbidity Prevention in Aging: The Role of Salutogenesis Amidst Crises addresses the urgent need to rethink disease prevention strategies for an aging population. The book begins by exploring how age-friendly environments support health-seeking behaviors. The next section focuses on developing personal skills such as resilience and self-efficacy for maintaining health during crises. Section III examines the reorientation of health services to support preventive care, including community care and diet promotion, while Section IV addresses the creation of policies that facilitate health-promoting interventions and integrate prevention strategies. Community engagement and empowerment in promoting health is emphasized in the fifth section.The book concludes by providing a framework for understanding disease prevention amidst crises, focusing on diverse racial, cultural, and socioeconomic experiences and ensuring equitable opportunities for lifelong disease prevention. This groundbreaking book emphasizes a salutogenic approach that focuses on factors promoting health rather than merely treating diseases. It provides a comprehensive framework for understanding how to maintain health and prevent diseases across the lifespan, even amidst challenges such as wars, climate change, and industrial hazards.

  • Geographic Atrophy in Age-related Macular Degeneration

    • 1st Edition
    • Jay Chhablani + 1 more
    • English
    Geographic Atrophy in Age-related Macular Degeneration provides a comprehensive resource on this flourishing discipline, focusing on accurate diagnosis, imaging features, clinical trials, differential diagnoses, and both established and emerging treatment options. The book details diagnostic processes using techniques such as visual acuity tests, dilated eye exams, fundus photography, optical coherence tomography (OCT), and fluorescein angiography, emphasizing the importance of early detection. It also differentiates geographic atrophy from other retinal conditions with similar symptoms, such as dystrophies, equipping practitioners with the knowledge for accurate diagnosis.Additional... it explores traditional management approaches like antioxidant supplements, lifestyle changes, and low vision aids, alongside novel treatments such as complement inhibitors, cell-based therapies, and gene therapy, to inform clinicians about the latest advancements and research in patient care. With the recent FDA approval for GA treatment, there has been significant interest in the retina community. This rapidly growing field necessitates a new book on geographic atrophy in age-related macular degeneration to address gaps in existing literature and provide up-to-date, comprehensive information.

  • Value-Based Healthcare in the Digital Age

    Economic Efficiency and Transformation
    • 1st Edition
    • Miltiadis D. Lytras + 2 more
    • English
    Value-Based Healthcare in the Digital Age: Economic Efficiency and Transformation addresses the transformation in global healthcare that has been driven by digital innovation, economic efficiency, and value-based care. The book provides comprehensive frameworks that integrate health economics, digital transformation, and patient-centered value delivery. Facing rising costs, aging populations, and chronic diseases, the healthcare sector also sees opportunities in AI, machine learning, blockchain, and IoT for smarter, more efficient delivery. Users will find an exploration of the economic implications of these technologies, offering strategies to align them with value-based care principles, optimize resources, and improve patient outcomes.For academics, policymakers, and healthcare professionals, this book bridges theory and practice with cutting-edge research and real-world case studies. It equips readers with the knowledge and frameworks to navigate the evolving healthcare landscape, emphasizing global perspectives and diverse technological applications, ultimately driving innovation and economic sustainability in healthcare delivery.

  • Digital Oncology Rehabilitation

    Integrating Technology into Cancer Rehabilitation and Palliative Care
    • 1st Edition
    • Manpreet Kaur + 3 more
    • English
    Digital Oncology Rehabilitation: Integrating Technology into Cancer Rehabilitation and Palliative Care reimagines cancer recovery through the lens of digital innovation. This edited volume bridges clinical expertise and technological advancement to transform physiotherapy and palliative care in oncology. The book explores AI-driven personalization, telephysiotherapy, wearable sensors, robotics, and predictive analytics, offering practical frameworks for remote assessment, symptom monitoring, and adaptive rehabilitation. Sections are supported by real-world case studies and ethical implementation strategies.Academics... clinicians, and researchers will benefit from a comprehensive, evidence-based guide that merges compassionate care with cutting-edge tools, thus empowering them to improve quality of life, create functional outcomes, and provide equitable access for cancer survivors and palliative patients.

  • Smart Approaches for Cancer Diagnosis, Therapy, and its Associated Challenges

    • 1st Edition
    • Paul A. Millner + 2 more
    • English
    Smart Approaches for Cancer Diagnosis, Therapy, and its Associated Challenges presents a comprehensive exploration of cutting-edge technologies transforming cancer care. This edited volume bridges foundational science with clinical relevance, offering insights into theranostics, nanomedicine, and molecular therapeutics. The book delves into advanced diagnostic tools such as biosensors and theranostic nanoparticles, and therapeutic innovations including peptide-drug conjugates, epigenetic modulation, and nucleic acid-based treatments. It addresses key challenges in glioblastoma, pediatric brain tumors, and drug-resistant cancers, while highlighting translational strategies that integrate diagnostics and therapy. Academics benefit from a multidisciplinary reference that supports research, fosters innovation, and enhances understanding of emerging cancer therapies. It equips researchers with the latest developments to advance precision medicine and improve patient outcomes.

  • GANs in Medical Diagnostics and Classification

    • 1st Edition
    • Abhishek Kumar + 1 more
    • English
    GANs in Medical Diagnostics and Classification explores the role of Generative Adversarial Networks (GANs) in addressing underdiagnosed and overlooked health challenges. The book bridges cutting-edge AI research with real-world medical applications, presenting interdisciplinary insights into how GANs enhance diagnostics, treatment precision, and disease surveillance across domains such as antimicrobial resistance, rare genetic disorders, and environmental health risks. It also examines ethical, policy, and accessibility dimensions of AI in healthcare. By combining technical depth with practical case studies, this volume equips medical researchers, AI engineers, and healthcare professionals with actionable knowledge to tackle silent epidemics using GAN-based tools.

  • Foundation of Microfluidics Device Technology

    • 1st Edition
    • Volume 226
    • English
    Foundation of Microfluidics Device Technology, Volume 225 presents the fundamentals of microfluidics and microfluidics devices, including computational design and fabrication, artificial intelligence and internet of things for microfluidics devices, materials, surface modifications and functionalization of microfluidics, fabrication of paper based microfluidics. Additional topics include microfluidics for generation of biomaterials, microfluidics for multi-omics analysis, lab-on-the-chip, microfluidics for 2D and 3D cell culture systems, microfluidics for drug and gene delivery, biomimetic models, and the economic considerations associated with microfluidics devices development.Specific chapters in this new release include An introduction to microfluidics and devices, Computational design and modeling of microfluidics devices, Artificial intelligence and IoT for microfluidics devices, Fabrication techniques for design of microfluidics devices, Materials, surface modification and functionalization of microfluidic devices, Fabrication of paper based microfluidics, Microfluidics in biomaterials generation and formulation, Microfluidics for chemical and biological analysis, and more.

  • Gut Health in Diabetes and Gastrointestinal Wellness

    Mechanisms and Clinical Applications
    • 1st Edition
    • Sushil Kumar Dubey + 2 more
    • English
    Gut Health in Diabetes and Gastrointestinal Wellness delves into the intricate relationship between gut microbiota and diabetes, emphasizing their significant impact on gastrointestinal health. This book bridges the gap between cutting-edge research and practical applications, offering a comprehensive exploration on how the gut microbiome affects both metabolic and gastrointestinal health. By examining current scientific findings, the book elucidates the mechanisms through which gut bacteria impact insulin sensitivity, glucose metabolism, and inflammatory responses. Additionally, practical strategies for optimizing gut health are provided, encompassing dietary recommendations, lifestyle modifications, and targeted interventions.The gut microbiome plays a crucial role in metabolic and gastrointestinal functions, and recent research has illuminated the mechanisms by which gut bacteria influence conditions such as diabetes, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). Dysbiosis, or the imbalance of gut microorganisms, can disrupt glucose metabolism, lead to insulin insensitivity, and promote chronic inflammation, all of which contribute to the progression and development of metabolic diseases like diabetes. Furthermore, gut dysbiosis is linked to various gastrointestinal disorders, often worsening symptoms and complicating treatment efforts.

  • Biology of Aging Accelerators

    Fundamentals, Hallmarks and Therapeutic Interventions
    • 1st Edition
    • Sandeep Kumar Singh + 1 more
    • English
    Biology of Aging Accelerators: Fundamentals, Hallmarks and Therapeutic Interventions explores how biological, genetic, and environmental factors affect cellular and systemic homeostasis and lead to accelerated aging. The book begins with a historical perspectives, highlighting the growth in immune system deterioration, chronic illness, and social issues. It then examines the hallmarks of aging, including primary, antagonistic, and integrative characteristics that may or may not be contributors. Subsequent chapters explore basic concepts and key accelerators in human biology, the role of biological clocks, and mechanisms of aging accelerators such as cellular senescence, DNA damage, and mitochondrial dysfunction.The book also addresses how different organs age at different rates and the brain's role as the body's aging integrator and provides actionable insights into innovative therapies aimed at reducing or stopping the signs and symptoms of aging, including developments in medications, lifestyle adjustments, regenerative medicine, and cutting-edge technologies like stem cell therapy and CRISPR. By integrating scientific research and practical insights, this book offers a realistic perspective on anti-aging research and stimulates novel ideas for improving quality of life.

  • Responsible AI in Healthcare

    Navigating the EU AI Act and Global Regulatory Frameworks
    • 1st Edition
    • Miltiadis D. Lytras + 3 more
    • English
    Responsible AI in Healthcare: Navigating the EU AI Act and Global Regulatory Frameworks examines how health systems design, deploy, and oversee AI under evolving legal and ethical mandates. It provides an integrated, practice‑oriented roadmap for compliance and responsible innovation. This book offers the first integrated, comparative treatment of the EU AI Act and global regulatory frameworks for healthcare, translating ethics and law into operational evaluation, governance, and value assessment. Through structured cases, decision tools, and stakeholder methods, it equips researchers and clinicians to design, validate, and deploy AI responsibly—and to keep learning as regulations evolve. Readers gain actionable tools, checklists, and frameworks to operationalize ethical AI, prepare for audits and certifications, and anticipate global convergence (“Brussels Effect”) shaping digital health. The volume serves clinicians, administrators, developers, policy and legal experts seeking rigorous yet accessible guidance.

  • Essentials of Stem Cell Biology

    • 4th Edition
    • Robert Lanza + 1 more
    • English
    Essentials of Stem Cell Biology, Fourth Edition is designed for the growing community of scientists, researchers, practitioners, and students embracing the latest advancements in stem cells. This comprehensive book, a collaboration of 7 editors and over 200 pioneering scholars and scientists, provides a thorough understanding of adult and embryonic stem cells. It combines fundamental concepts with cutting-edge research in specific organ systems, ensuring a robust foundation for anyone entering the field. Beyond the basics, the book delves into early development and the differentiation of ectoderm, mesoderm, and endoderm.It covers methods, applications to human diseases, regulation, ethics, and patient perspectives, leaving no stone unturned in the stem cell domain.

  • Diabetic Neuropathy

    • 1st Edition
    • Shahidul Islam
    • English
    "Recent Therapeutic Targets for the Prevention and Management of Diabetic Complications: Neuropathy" covers recent research and therapeutic approaches of this diabetic complication for the management of diabetes. It is a detailed reference to understand the pathogenesis of diabetes to alleviate the overall complications of neuropathy to improve patient care. It is uniquely focused on the different aspects of neuropathy with a focus on the molecular and biological pathways (therapeutic target) to detect an early diagnosis to better manage the disease and improve patient care. The book is useful to anyone in the field particularly those who do research investigations, and day-to-day practice in the area of diabetes.

  • Genetic Advances in Inborn Errors of Immunity

    • 1st Edition
    • Volume 117
    • English
    Genetic Advances in Inborn Errors of Immunity, published as Volume 117 of the serial Advances in Genetics, provides a comprehensive and up‑to‑date overview of the rapidly evolving genetic landscape underlying inborn errors of immunity (IEI). Bringing together authoritative contributions from leading experts, this volume examines how advances in genomics, molecular diagnostics, and functional immunology have transformed the understanding, classification, and clinical management of primary immunodeficiency disorders. The chapters span severe monogenic conditions to complex, polygenic phenotypes, highlighting both mechanistic insights and translational implications. Collectively, the volume serves as an essential reference for researchers and clinicians seeking to understand how genetic discoveries are reshaping immunology and precision medicine.

  • Principles and Practice of Nephrocardiology

    • 1st Edition
    • Parta Hatamizadeh
    • English
    Principles and Practice of Nephrocardiology provides a comprehensive introduction to the interdisciplinary subspecialty of Nephrocardiology. The book includes detailed descriptions, along with an in-depth exploration of its primary elements and topics. Coverage spans pathophysiology, epidemiology, prevention, diagnosis, prognosis, monitoring, therapy, risk factors, and the systemic diseases that involve both nephrology-related conditions and cardiovascular diseases. The book guides clinicians and general practitioners in multiple interdisciplinary specialties through diagnostic, preventive, and therapeutic approaches to a wide variety of patient populations. It also opens a myriad of new avenues for future research and guidance for approaching multiple medical topics.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 136
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Nanocarrier-Based Immunotherapy

    Emerging Frontiers in Cancer
    • 1st Edition
    • Bhupendra G. Prajapati + 1 more
    • English
    Nanocarrier-Based Immunotherapy: Emerging Frontiers in Cancer explores innovative nanotechnology approaches to enhance cancer immunotherapy. This comprehensive volume addresses the design, mechanisms, and clinical potential of nanocarriers such as polymeric nanoparticles, liposomes, dendrimers, exosomes, and inorganic nanomaterials in modulating immune responses against tumors. The book provides in-depth coverage of foundational principles, recent advancements, and translational strategies. In addition, it discusses how nanocarriers improve targeted delivery, overcome tumor immune evasion, and enable combination therapies.Chapters highlight cutting-edge topics like AI integration, safety profiles, and regulatory considerations, offering a multidisciplinary perspective. Designed for an academic audience, this resource facilitates understanding of nanomedicine’s role in cancer treatment. It equips researchers, clinicians, and students with scientific insights, novel strategies, and practical solutions to accelerate the development of next-generation immunotherapies.

  • Empowering Health through Lifestyle Medicine

    The Essential Guide for Preventing and Managing Chronic Disease
    • 1st Edition
    • John Anthony Stevens
    • English
    Empowering Health through Lifestyle Medicine: The Essential Guide for Preventing and Managing Chronic Disease combines the most updated and available research with personal insights and experience, using the Lifestyle Medicine 6 pillar framework. The book engages readers not only in the description and efficacy of LM but also in its knowledge and discussions on concepts and behaviors for managing nutrition, physical activity, stress, mental health, and how our interactions with the environment can create a healthier, happier life. It will encourage clinicians to engage their patients more often, and more practically, with lifestyle medicine, while also helping consumers engage with their clinicians.With a goal of helping clinicians and healthcare related professionals prevent and manage lifestyle-related illnesses for life, this evidenced-based book can be used by anyone in healthcare. It is also ideal for those researching illness prevention and chronic disease management to improve health research practice and patient outcomes.

  • Protein Folding

    • 1st Edition
    • Timir Tripathi
    • English
    Protein Folding explores the fundamental and applied aspects of protein folding, misfolding, and stability in biological systems. Focusing on the biochemical principles and molecular dynamics that drive folding processes, the book provides readers with a comprehensive understanding of how proteins attain their native structures and what happens when this process goes awry. Covering diverse approaches from structural biology, biophysics, enzymology, and systems biology, the book highlights the molecular basis of folding pathways and the pathological consequences of misfolded proteins in diseases such as Alzheimer's, Parkinson's, and cystic fibrosis. It integrates insights into chaperone function, folding kinetics, and the cellular quality control mechanisms that safeguard proteostasis. Across its chapters, the book addresses key themes including protein folding landscapes, folding intermediates, the role of cellular compartments, aggregation-prone sequences, and the impact of mutations. It also examines current methodologies for studying protein folding, including spectroscopy, calorimetry, and computational simulations, and considers emerging therapeutic strategies that target misfolding and aggregation. This book is a valuable resource for biochemists, molecular biologists, biotechnologists, enzymologists, and researchers in protein science. It supports academic researchers, postgraduate students, and pharmaceutical scientists working to understand protein behavior and develop interventions for protein misfolding diseases.

  • PACAP

    From Discovery to Function
    • 1st Edition
    • David Vaudry + 1 more
    • English
    PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Methods in Systems Bioinorganic Chemistry

    • 1st Edition
    • Volume 741
    • English
    Methods in Systems Bioinorganic Chemistry, Volume 741 provides understanding of high-level properties involving metals in biology that are founded on molecular or mechanistic level interactions. Currently, there is no established “tool kit” for studying bioinorganic systems, so the methods included in the book span a diverse range of topics and approaches, from imaging to proteomics, from metals-in-mice to mathematical modeling. Specific chapters cover Inductively Coupled Plasma Mass Spectrometry (ICP-MS)-based methods to quantify transition metals in cells and vertebrate models, ICP-MS elemental analysis in tissue samples, and much more.Additional chapters delve into An inductively-coupled-... triple quadrupole method with oxygen for the determination of essential elements and protein concentration, Calculating metal speciation of proteins inside cells, Probing biological copper in the subfemtomolar regime, Using LC-ICP-MS chromatography to detect and characterize Labile Metal Pools, Linking dynamic bioinorganic chemistry processes of toxic metals in the bloodstream to establish their exposure-response relationship in humans, Contextualizing X-ray fluorescent microscopy – high resolution X-rays meet subcellular morphology, Chemoproteomic profiling of transition metal binding sites in bacterial proteomes, Heme Labeling by Proximity (HeLP) to Identify Hemoproteins, and much more.

  • Arginase: Structure, Function, and Therapeutic Targeting

    • 1st Edition
    • Volume 740
    • English
    Arginase: Structure, Function, and Therapeutic Targeting, Volume 740 in the Methods in Enzymology series, provides a comprehensive, methodology-driven perspective on arginase research spanning molecular, biochemical, and translational domains. Chapters in this new release include Expression, Purification, and Structural Characterization of Human and Leishmania Arginase with Comparative Analysis of Structures from the Protein Data Bank, Synthesis of First-Generation Arginase Inhibitors, Computational and Structure-Guided Design of Arginase Inhibitors, Metal Substitution in Arginase: Experimental Approaches to Study Metal-Dependent Catalysis, Therapeutic Arginase Formulations: PEGylation, Stability, and Advanced Delivery Systems, and much more.Additional chapters cover Dual ARG1/ARG2 Inhibition: Experimental and Structural Strategies for Inhibitor Design and Optimization, Synthesis of Second-Generation Arginase Inhibitors, Cryo-EM Workflow and Structural Characterization of Arginase–Antibody Complexes, Development and Validation of an Electrochemical Assay for Arginase Activity, Experimental and Structural Analysis of H. pylori Arginase in Gastric Immune Evasion, Agmatinase and Alternative Arginine Utilization Pathways in Bacteria: Biochemical and Functional Perspectives, Catalytic Diversification of the Arginase Fold: Structural and Mechanistic Insights from DcsB, Beyond Arginase: Structural Biology of the Extended Guanidinase Family, Plant Arginase: Structural and Functional Roles in Nitrogen Metabolism, and much more.

  • Blockchain-Enabled Innovations in Location-Based Services for Healthcare

    • 1st Edition
    • Ajay Kumar Gupta + 3 more
    • English
    Blockchain-Enabled Innovations in Location-Based Services for Healthcare addresses the growing need for secure, intelligent healthcare solutions integrating location-based services (LBS), Internet of Things (IoT), and blockchain technologies. This reference explores how these technologies transform healthcare delivery improving autonomy and real-time care while safeguarding sensitive data. It responds to the challenges posed by the proliferation of wearable sensors and smart medical devices by proposing decentralized, privacy-preserving frameworks.The book’s comprehensive chapters cover blockchain trust models, adaptive privacy for patient trajectories, wearable computing, deep learning for medical imaging, secure communication in healthcare IoT, and AI-powered diagnostics. Contributions from global experts provide case-driven analyses and technical depth, addressing current challenges in healthcare data security, interoperability, and predictive modeling. The interdisciplinary approach integrates computer science, data privacy, and healthcare informatics, making it a valuable resource for researchers and professionals.Blockc... Innovations in Location-Based Services for Healthcare benefits academic researchers, industry practitioners, graduate students, and policymakers by offering cutting-edge knowledge in secure, decentralized healthcare systems. It equips readers with advanced methodologies and practical solutions to design inclusive healthcare technologies, fostering innovation in smart health monitoring, medical image analysis, and data-driven diagnostics within privacy-compliant frameworks.

  • Thiamine Pyrophosphate (TPP)-Dependent Enzymes

    • 1st Edition
    • Volume 736
    • English
    Thiamine Pyrophosphate (TPP)-Dependent Enzymes, Volume 736 in the Methods in Enzymology series covers this diverse group of ubiquitous enzymes with timely chapters on Methods for Studying ThDP-dependent Mycobacterial MenDs (SEPHCHC Synthases), Mammalian 2-hydroxyacyl-CoA lyases, discovery and assays, Anti-infective target 1-deoxy-d-xylulose-5... synthase (DXS) and drug design for enzyme inhibition, Expression, Purification, and Mechanistic Studies of DXP synthases from Deinococcus radiodurans, Plasmodium falciparum, and Plasmodium vivax, Comparison of the catalysis of ThPP-dependent enzymes AHAS, ALS, and DXS, and much more.Additional sections cover Plant and fungal acetohydroxyacid synthases (AHAS): Methods for heterologous expression, kinetic characterization, and structural analysis, Biochemical and Structural characterization of novel ‘split-gene’ archeal transketolases, 4-Hydroxybenzoylform... decarboxylase enzymes from Rhodococcus jostii RHA1 and Pseudomonas fluorescens Pf-5: characterization and involvement in bacterial lignin degradation, Engineering of phosphoketolase from Bifidobacterium adolescentis for increased activity on non-phosphorylated substrates and application in a cell-free reaction system for ATP regeneration, Repurposing TPP-dependent enzymes with anodic oxidation for the conversion of aldehydes to enantioenriched carboxylic acids, and much more.

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