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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Human-Centred AI For Intelligent Healthcare

    Approaches and Technologies
    • 1st Edition
    • Mahmoud Hassaballah + 1 more
    • English
    Human-Centred AI For Intelligent Healthcare: Approaches and Technologies provides state-of-the-art AI technologies and healthcare tailored to human needs, highlighting the various ways AI is reshaping patient care, diagnostics, treatment modalities, and overall healthcare systems. From the intricacies of precision medicine to interventions in mental health, this reference provides a diverse array of AI applications. It addresses ethical considerations while emphasizing the transformative potential that AI holds for the healthcare industry. This reference is an essential companion for healthcare professionals, researchers, policymakers, technologists, and enthusiasts navigating the swiftly evolving landscape of AI in healthcare. Bridging a critical gap in literature, it offers a consolidated resource that not only explores the multifaceted applications of AI in healthcare but also underscores the importance of maintaining a human-centric approach in the integration of these technologies. With a focus on forecasting future trends and implications, this reference equips readers with the knowledge to stay at the forefront of the dynamic field of healthcare technology and empowers them to anticipate changes and adapt their strategies proactively in the face of evolving healthcare landscapes.
  • Artificial Intelligence in Clinical Medicine

    General Concepts and Specific Applications
    • 1st Edition
    • Marianne Legato J + 1 more
    • English
    Artificial Intelligence in Clinical Medicine: General Concepts and Specific Applications explores the evolution and application of artificial intelligence (AI) in medicine, highlighting both its potential and challenges. The initial discussion outlines past failures in integrating AI into healthcare, followed by a review of FDA-approved AI medical devices and their implications for diagnostics. Subsequent sections examine the transformative impact of large language models, the ethical application of AI in clinical settings, and the role of AI in enhancing patient safety. Various specialties, such as cardiology and pulmonary disease, illustrate AI's capabilities in improving diagnostics and treatment. The discussions extend to diabetes care, dermatology, obstetrics, and radiology, emphasizing the need for ethical considerations and quality assessments to ensure AI aligns with human values and improves patient outcomes across diverse healthcare contexts.
  • AI and Personalized Medicine in Cardiometabolic Disease

    Principles, Applications and Future Perspectives
    • 1st Edition
    • M. Salman Khan + 2 more
    • English
    AI and Personalized Medicine in Cardiometabolic Disease: Principles, Applications and Future Perspectives offers a comprehensive and timely exploration of how artificial intelligence (AI) is revolutionizing personalized care for cardiometabolic diseases. This authoritative volume bridges foundational AI concepts with cutting-edge translational applications, guiding clinicians, researchers, and data scientists through the integration of AI-driven tools in diagnosis, risk prediction, biomarker discovery, and tailored treatment strategies. Featuring real-world case studies, ethical and regulatory insights, and future-focused discussions on emerging technologies and equitable implementation, this book is an essential resource for healthcare professionals and scientists aiming to harness AI’s full potential to improve patient outcomes in cardiovascular and metabolic health.
  • SGLT2 Inhibitors in Cardiovascular Diseases

    Mechanisms, Clinical Impact, and Future Directions
    • 1st Edition
    • Tong Liu
    • English
    SGLT2 Inhibitors in Cardiovascular Diseases: Mechanisms, Clinical Impact, and Future Directions reviews the impact of SGLT2 inhibitors on cardiovascular health in individuals with type 2 diabetes, chronic kidney disease, heart failure, and atherosclerosis. The book synthesizes preclinical and clinical evidence to highlight the cardiovascular benefits of these drugs, initially developed for hyperglycemia management. It details recent studies on SGLT2 inhibitors' effects on cognitive dysfunction, sudden death, ventricular arrhythmias, heart remodeling, and cancer risks in diabetic patients.In addition, it compares SGLT2 inhibitors with DPP4 inhibitors, emphasizing the efficacy of empagliflozin and dapagliflozin in reducing syncope and cardiovascular mortality, supported by trials like EMPA-REG OUTCOME and DECLARE-TIMI 58. Addressing a gap in literature, the book provides a comprehensive overview of SGLT2 inhibitors' cardiovascular benefits in high-risk populations, including atrial fibrillation and syncope. It offers valuable insights and recommendations for clinicians, researchers, and policymakers managing cardiovascular risk.
  • RNA-Binding Proteins Part B

    • 1st Edition
    • Volume 744
    • English
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Proteolytic Enzymes and their Inhibitors in Infectious Pathogens

    • 1st Edition
    • Theresa Coetzer
    • English
    Proteolytic enzymes are found in all life forms, where they catalyze peptide bond hydrolysis during essential biological processes. Proteases of various pathogens have also been shown to use endogenous protease inhibitors to regulate the activity of host proteolytic enzymes encountered during infection.Proteolyti... Enzymes and their Inhibitors in Infectious Pathogens brings together key experts to provide a thorough discussion of proteolytic enzymes and their endogenous inhibitors found in parasites, bacteria, and viruses. The book focuses on the respective roles of the different catalytic classes of proteolytic enzymes and their protein-protease inhibitors at the host-infectious organism interface, and how this knowledge may inform drug and vaccine design. Following a foundational overview of proteases and macromolecular inhibitors of pathogenic organisms, authors discuss recent research on distinct classes of proteolytic enzymes in pathogens. Classes include aspartic proteases, cysteine proteases, metalloproteases, serine proteases, and threonine proteases with experts contributing chapters on distinct enzymes and inhibitors. New methods to identify protease substrates and inhibitors are also provided, with step-by-step protocols to advance new research and drive drug discovery.
  • Probiogenomics and Probiomics

    Concepts, Techniques, Applications, and Achievements
    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    Probiogenomics and Probiomics: Concepts, Techniques, Applications, and Achievements is a pioneering reference book that marks a significant milestone in the emerging fields of probiogenomics and probiomics. As the first comprehensive resource in these disciplines, the book offers a detailed exploration of how genetic insights and omics technologies are revolutionizing our understanding of probiotics and their application in health and disease. Spanning three detailed sections, the book begins by grounding readers in the fundamental concepts of probiotics, including their roles in health enhancement and disease prevention. It progresses into a deep dive into advanced genomic and post-genomic technologies, revealing how these tools are used to dissect and harness the health-promoting capacities of probiotics. From the structure and function of probiotic genomes to the cutting-edge applications in synthetic biology and multi-omics, the book encapsulates the latest advancements and methodologies in the field. The final sections focus on the practical and clinical applications of these microbial marvels, discussing their impact on healthcare, biotechnology, and therapeutics. Whether it's developing new biotechnological products or enhancing therapeutic efficacy, this book covers a broad spectrum of applications, making it an invaluable resource for undergraduate and postgraduate students, researchers, clinicians, and industry professionals involved in drug and probiotics development. With contributions from over ten global experts, "Probiogenomics and Probiomics" not only educates but also inspires, providing a thorough understanding of modern probiogenomics and its potential to shape the future of personalized medicine and healthcare.
  • A Comprehensive Guide to Surgical Oncology

    • 1st Edition
    • Aqeel Shakir Mahmood + 2 more
    • English
    A Comprehensive Guide to Surgical Oncology is an authoritative reference that meticulously covers the surgical management of various cancers. Each section delves into the latest surgical techniques, treatment protocols, and post-operative care strategies, supported by up-to-date research and clinical evidence. Enriched with detailed illustrations, case studies, and expert insights, this book is an indispensable resource for professionals and students alike. The primary purpose of this book is to provide a comprehensive, up-to-date resource that addresses the current challenges and advancements in surgical oncology. As cancer treatment evolves rapidly with continuous improvements in surgical techniques and multidisciplinary care, there is a pressing need for a new resource that synthesizes these developments into a coherent guide. This book aims to fill that gap by offering a thorough overview of the latest surgical oncology practices, thereby enhancing the knowledge and skills of its readers. This book solves several key problems for its readers by bridging the gap between rapidly advancing research and clinical practice, ensuring access to the latest information. It consolidates a vast amount of information into one comprehensive volume, saving readers the time and effort of consulting multiple sources. Providing practical guidance on the surgical management of a wide range of cancers, it helps practitioners make informed decisions in clinical settings. For students and trainees, it serves as a valuable educational tool that covers both foundational knowledge and advanced concepts in surgical oncology, offering multidisciplinary insights that foster a better understanding of the collaborative efforts required in cancer treatment.
  • Rational 'Co-Design' of Targeted Anticancer Therapeutics

    Integrating Immuno-Oncology, Biomaterials, and Translational Systems
    • 1st Edition
    • Y. Manojkumar + 3 more
    • English
    Rational 'Co-Design' of Targeted Anticancer Therapeutics: Integrating Immuno Oncology, Biomaterials, and Translational Systems presents a unified, system level framework that designs molecules, carriers, and delivery pathways concurrently for clinically translatable cancer therapies. The book details how electronic structure, molecular recognition, biomaterial compatibility, immune microenvironment dynamics, and ADMET/AI models integrate into end to end decision frameworks—from in silico prediction to experimental validation and regulatory readiness. Readers gain a pragmatic path to faster, safer translation: case informed guidance, co design checklists, and criteria for affordability, scalability, and sustainability enable researchers and advanced students to move beyond fragmented, sequential development toward robust therapeutic systems.
  • Aging and Troponin

    Clinical Implications and Uses Beyond Diagnosis
    • 1st Edition
    • Gary Tse + 3 more
    • English
    Aging and Troponin: Clinical Implications and Uses Beyond Diagnosis examines the multifaceted role of troponin in clinical medicine, with a special focus on aging. This comprehensive reference provides essential technical knowledge, diagnostic and prognostic applications, and model development insights from leading experts in clinical biochemistry, pathology, and epidemiology. The book emphasizes the impact of aging on troponin test results and their interpretation, addressing age-related disorders such as renal failure. Sections cover the technical aspects of troponin assays, comparing traditional and high-sensitivity assays and exploring point-of-care testing advancements.The book also examine age-related changes and intra- and inter-individual variability in troponin levels, focuses on diagnostic applications, including troponin as a biomarker for cardiac injury and dysfunction, and the effects of age, sex, and renal impairment on diagnostic sensitivity and specificity, and discusses troponin's prognostic value for mortality in various conditions, including heart disease, sepsis, and COVID-19, and its role as a marker of organ biological age. The final section offers cutting-edge insights into the clinical applicability of troponin testing, highlighting the benefits of incorporating high-sensitivity assays into clinical workflows and providing perspectives and age-related considerations from practicing physicians on implementation and evidence-based practice.
  • Trauma Informed Care in Pediatric Acute and Critical Care Setting

    An Approach for Promoting Resilience and Recovery
    • 1st Edition
    • Trevor A. Hall + 1 more
    • English
    Trauma Informed Care in Pediatric Acute and Critical Care Settings: An Approach for Promoting Resilience and Recovery is a groundbreaking resource addressing the urgent need for trauma-informed care (TIC) in pediatric intensive care units (PICUs) and acute care settings. Each year, countless children and their families navigate the overwhelming challenges of hospitalization due to life-threatening injuries or illnesses. This book explores the profound psychological impacts of such experiences and underscores the necessity of integrating TIC principles to foster resilience and enhance recovery. Within its pages, readers will discover a comprehensive exploration of TIC elements and principles, such as recognizing signs of psychological trauma, ensuring safety, and promoting trustworthiness and empowerment. The text examines pediatric medical traumatic stress, secondary trauma, and the importance of TIC for long-term health outcomes. Featuring contributions from a multidisciplinary team of experts, the book offers practical strategies for developing and sustaining TIC programs. It provides insights into the unique environment of pediatric acute settings, the roles of healthcare professionals, and the global landscape of healthcare systems, while also addressing essential aspects of follow-up care. Trauma Informed Care in Pediatric Acute and Critical Care Settings: An Approach for Promoting Resilience and Recovery equips healthcare professionals with the knowledge to improve patient care, reduce professional burnout, and advance the field of pediatric acute care. With its focus on awareness, readiness, detection, management, and integration of TIC principles, this essential guide is poised to transform the experience of children, families, and healthcare teams by fostering a culture of healing and resilience.
  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 137
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Pioneering Precision in Cancer Treatment through 3D Bioprinting

    • 1st Edition
    • Anand Krishnan + 3 more
    • English
    Pioneering Precision in Cancer Treatment through 3D Bioprinting explores the transformative impact of 3D bioprinting on cancer therapy. This groundbreaking book examines innovative techniques revolutionizing cancer care, from creating patient-specific tumor models to accelerating drug discovery and enabling personalized treatments. It offers a comprehensive look at how 3D bioprinting is reshaping oncology. The book details the creation of intricate tumor models that mimic the in vivo environment, enabling precise drug testing and individualized treatment plans. It highlights 3D bioprinting's role in drug screening, tumor modeling, and creating implantable scaffolds for cancer treatment.By manipulating cell arrangements and microenvironments, 3D bioprinting produces accurate cancer models. For the academic audience, this book blends bioengineering, medical insights, and real-world applications. It provides valuable case studies and developments in 3D cancer model creation, enhancing the understanding of oncogenesis, tumor progression, and therapy responses.
  • Omics Approaches in Rhizosphere Microbiology: Part B

    • 1st Edition
    • Volume 61
    • English
    Omics Approaches in Rhizosphere Microbiology: Part A offers a definitive, systems-level exploration of the complex microenvironment where plant roots and soil microorganisms interact. As global agriculture faces the dual challenges of climate change and food insecurity, understanding the rhizosphere has shifted from traditional culture-dependent isolation to advanced high-throughput molecular auditing. This volume serves as a comprehensive, technically rigorous manual and structural roadmap, bridging foundational rhizosphere biology with the cutting-edge structural analytical tools of modern polyphasic science.
  • Sustainable Digital Medicine

    Green Technology Integration for Inclusive Health Systems
    • 1st Edition
    • Patricia Ordonez de Pablos + 1 more
    • English
    Sustainable Digital Medicine: Green Technology Integration for Inclusive Health Systems explores the transformative potential of digital innovation in healthcare. This edited volume brings together global perspectives on how emerging technologies can modernize health systems while promoting sustainability and inclusivity. The book covers key topics such as AI integration in medicine, digital tools for citizen empowerment, modernization of medical education, and the environmental impact of healthcare technologies. It includes case studies from Asia, Europe, the Gulf Region, and the Americas, offering comparative insights and practical applications. Contributors analyze challenges and opportunities in digital health, with policy recommendations for decision-makers. Designed for researchers, academics, and policymakers, this book provides timely knowledge and actionable strategies. Readers gain a deeper understanding of digital transformation in healthcare, new professional skillsets, and the role of technology in building resilient, equitable health systems aligned with global sustainability goals.
  • Dissolvable Microneedles (DMNS) For Cancer Diagnosis and Treatment

    • 1st Edition
    • Neetu Talreja + 3 more
    • English
    Dissolvable Microneedles (DMNS) For Cancer Diagnosis and Treatment presents a comprehensive, lab‑to‑clinic overview of dissolving microneedles (DMNs) for cancer diagnosis and therapy, emphasizing painless, minimally invasive delivery and localized treatment. The book details DMN materials, design, and fabrication—includin... AI‑enabled and 3D‑printed approaches—then advances to theranostic applications such as immunotherapy, photodynamic therapy, exosome‑loaded systems, and stimulus‑responsive platforms. Translation topics cover regulation, scale‑up, and CMC, alongside supportive strategies during chemotherapy.Academi... readers gain a structured synthesis of recent advances, practical methods, and clinical outlooks, positioning DMNs as patient‑friendly, cost‑effective tools with significant potential to revolutionize cancer care.
  • Understanding Molecular Processes using Electrochemical Methods

    • 1st Edition
    • Ashis Kumar Satpati + 1 more
    • English
    Understanding Molecular Processes using Electrochemical Methods offers a detailed compendium of techniques for molecular analysis. The book considers step and sweep techniques, scanning electrochemical microscopy, spectroelectrochemic... techniques, electrochemiluminesc... and scanning probe techniques while also exploring COSMOL multiphysics simulation, electroanalysis in biomedical and clinical applications, and future prospects for electrochemical techniques. Chapters focus on evaluating redox reactions, biological interactions, kinetics, quorum sensing, biofilm formation, surface modification and more molecular aspects. This volume offers a deep-dive into the fundamental principles behind the latest electrochemical techniques, equipping researchers with practical guidance for their own experiments.Users will find this to be an ideal reference for researchers working across a range of disciplines including molecular biology, bioanalytical chemistry, biomedical science, and translational medicine.
  • Imaging of Foreign Bodies, Aesthetic Implants, and Mal-Positioned Medical Devices in Humans

    • 1st Edition
    • Ajay K. Singh
    • English
    Imaging of Foreign Bodies, Aesthetic Implants, and Mal-Positioned Medical Devices in Humans offers an essential resource for radiologists, surgeons, emergency physicians, and related specialists involved in diagnosing and managing foreign bodies and medical device complications. This reference addresses the growing complexity of foreign body detection across diverse anatomical regions, emphasizing the need for precise imaging protocols and interpretation skills. It systematically covers the full spectrum of clinical presentations, from ingested and aspirated objects to iatrogenic and traumatic foreign bodies, integrating advanced imaging modalities such as plain radiography, CT—including innovative techniques like dual-energy CT—MRI, and ultrasound. The content is structured into detailed chapters, each providing insights into typical imaging signs, modality-specific advantages and limitations, and management strategies tailored to complex cases. The book aims to enhance diagnostic accuracy, reduce uncertainty, and facilitate prompt, appropriate intervention, ultimately improving patient outcomes. Its comprehensive scope and focus on emerging imaging technologies make it an indispensable tool for clinicians facing daily challenges in foreign body detection and management, as well as for researchers and educators seeking a current, authoritative reference.
  • Agentic AI for Healthcare 5.0

    Intelligent Agents, Autonomous Systems, and Governance Frameworks
    • 1st Edition
    • Ondrej Krejcar + 5 more
    • English
    Agentic AI for Healthcare 5.0: Intelligent Agents, Autonomous Systems, and Governance Frameworks is an edited volume that examines how autonomous agents reshape healthcare toward Healthcare 5.0. It integrates foundations, clinical and operational applications, and governance concerns to provide a cohesive, practitioner-informe... perspective. The book covers foundational agentic models, decision-making, and cyber-physical infrastructures; it then presents application-focused chapters on autonomous clinical decision support, patient monitoring, medical robotics, and hospital workflow orchestration, followed by chapters on distributed learning, semantic interoperability, digital twins, and cybersecurity. For researchers in bioinformatics, clinicians, and policymakers, it clarifies when and how agentic AI adds value, supports safe deployment, and informs governance. It equips readers with evaluation frameworks, design patterns, and policy guidance to advance responsible adoption of intelligent agents in Healthcare 5.0.
  • Wound Microenvironment Responsive Smart Dressing for Effective Healing

    • 1st Edition
    • Mohit Kumar + 4 more
    • English
    Wound Microenvironment Responsive Smart Dressing for Effective Healing presents a cutting-edge scientific exploration of phytoconstituent-bas... smart wound dressings engineered to accelerate and improve tissue repair. Bridging the therapeutic wisdom of traditional herbal medicine with advanced biomaterials, nanotechnology, polymer science, and bioengineering, this volume highlights how natural bioactive compounds can be transformed into clinically viable wound therapies. The book provides an integrated understanding of the molecular and cellular mechanisms governing wound healing, and demonstrates how stimuli-responsive delivery platforms—sensitive to pH, temperature, enzymes, ROS, or glucose—can enable precise, controlled release of phytochemicals directly at the wound site. These innovative systems overcome limitations of conventional formulations, such as instability, poor solubility, low bioavailability, and lack of targeted action. With contributions spanning smart hydrogels, nanocarriers, microneedles, 3D/4D printing, and AI-assisted wound monitoring, this multidisciplinary reference offers both foundational principles and translational guidance. Case studies and globally inclusive perspectives ensure broad relevance for researchers, clinicians, and formulation scientists working toward next-generation wound management solutions.
  • Practice-Based Physiology in Allied Health Sciences

    From Evidence to Clinical Application
    • 1st Edition
    • Satyajit Tripathy + 3 more
    • English
    Practice-Based Physiology in Allied Health Sciences: From Evidence to Clinical Application provides a comprehensive, systems-based exploration of human physiology specifically designed for applied health sciences. It moves beyond conventional textbook knowledge to integrate cardiovascular, respiratory, neurological, endocrine, and musculoskeletal systems within the context of real-world clinical and functional applications. By emphasizing translational physiology, the text helps readers understand how cellular and systemic mechanisms directly inform therapeutic assessment, intervention planning, and patient-centered care. The book’s multidisciplinary perspective supports students and practitioners in physiotherapy, occupational therapy, nursing, sports medicine, and behavioral science—highlighting physiology as a common language that unites diverse healthcare disciplines. Through detailed explanations, case studies, and applied scenarios, readers learn to interpret physiological data, identify dysfunctions, and design interventions grounded in scientific evidence. Ultimately, this resource bridges the gap between science and practice by linking physiological understanding to outcomes such as recovery, mobility, pain management, fatigue reduction, and overall well-being. It encourages critical thinking, clinical reasoning, and interprofessional collaboration—ensuri... that learners not only grasp how the human body functions but also how that knowledge can meaningfully improve health, performance, and quality of life.
  • Digital Medical Twins for Personalized Healthcare

    Generative AI and Multi-Modal Approaches for Predictive Diagnostics and Precision Medicine
    • 1st Edition
    • Yogesh Kumar + 3 more
    • English
    Digital Medical Twins for Personalized Healthcare: Generative AI and Multi-Modal Approaches for Predictive Diagnostics and Precision Medicine presents a rigorous, evidence-based framework for building patient-specific digital replicas that support clinical decision-making and research innovation. The field integrates electronic health records, imaging, genomics, and continuous wearable data into dynamic models that simulate disease trajectories and treatment responses. Readers confront a evolving landscape of AI methods, privacy requirements, and regulatory expectations; this book offers a coherent, practical reference designed for scientists, and health-system professionals seeking to translate digital twins from concept to care delivery.
  • Nanomaterials for Stem Cell Modulation

    Innovation and Clinical Applications
    • 1st Edition
    • Syed Mahmood + 3 more
    • English
    Nanomaterials for Stem Cell Modulation: Innovation and Clinical Applications provides a comprehensive exploration of how nanotechnology is transforming stem cell science and regenerative medicine. This authoritative volume examines the physicochemical properties of nanomaterials, their interactions with stem cells, and their capacity to direct stem cell behaviors such as proliferation, differentiation, and therapeutic delivery. By blending foundational principles with cutting-edge innovations, the book bridges the gap between basic laboratory discoveries and clinical translation. Written by experts in the field, the book addresses the critical need for an integrated resource that unifies current knowledge with emerging research and practical applications.While interest in nanotechnology and stem cells continues to grow, the literature remains fragmented. This book fills that gap by offering structured insights, case studies, and guidance on selecting nanomaterial systems tailored to specific therapeutic goals, while also navigating regulatory and translational challenges. Designed for researchers, graduate students, and professionals, the text serves as both a practical guide and an academic reference across disciplines including nanotechnology, stem cell biology, regenerative medicine, tissue engineering, biomedical engineering, and pharmaceutical sciences.
  • Federated Quantum Convolutional Neural Networks in Healthcare

    Enhancing Privacy and Efficiency
    • 1st Edition
    • Abhishek Kumar + 3 more
    • English
    Federated Quantum Convolutional Neural Networks in Healthcare: Enhancing Privacy and Efficiency explores the innovative intersection of quantum computing and federated learning in the context of healthcare. As medical data grows exponentially and privacy concerns intensify, this book addresses the urgent need for secure, scalable AI solutions that enable collaborative data analysis without compromising patient confidentiality. It offers a detailed examination of the theoretical foundations of quantum machine learning and federated systems, complemented by practical case studies spanning medical imaging, genomics, and disease diagnosis. The content delves into architecture design, security protocols, and optimization techniques, equipping researchers and practitioners with the tools to develop privacy-preserving AI models tailored for medical applications. The book also discusses regulatory considerations, deployment challenges, and future research directions, positioning itself as a vital resource for advancing healthcare AI. Its comprehensive approach bridges fundamental science and real-world implementation, empowering healthcare professionals, data scientists, and policy makers to harness next-generation quantum federated systems for improved patient outcomes and data security. This resource is essential for those seeking to implement cutting-edge AI technologies in healthcare, ensuring secure, efficient, and collaborative medical data analysis.
  • Fluid Dynamics of Viral Transmission

    • 1st Edition
    • Mehrzad Shams + 1 more
    • English
    Fluid Dynamics of Viral Transmission is an essential exploration into the transmission dynamics of COVID-19, focusing specifically on the airborne spread of respiratory aerosols carrying infectious viruses. In light of the recent global pandemic, it offers crucial insights into the complex interaction between fluid dynamics and viral transmission and provides practical solutions for minimizing risks in indoor environments. The book delves into CFD simulations, optimizing ventilation systems, air filtration strategies, and spatial layout modifications. It evaluates mitigation measures such as mask-wearing, physical distancing, and occupancy limits, aiming to equip readers with the knowledge to create safer indoor spaces. This book is ideal for public health officials, policymakers, healthcare professionals, engineers, researchers, and academics in fluid mechanics, computational fluid dynamics, epidemiology, and virology.
  • Fostering Research Integrity

    A Practical Guide for Research Ethics
    • 1st Edition
    • Ashima Anand
    • English
    Fostering Research Integrity: A Practical Guide to Research Ethics, a new release in Elsevier's series, Hot Topics in Physiology, addresses the aspects of research integrity, international normative instruments governing research integrity, and research practices.With chapters on animal research ethics and research practices for human subjects, this book is a valuable resource to all physiology researchers and beyond.
  • The Pancreatic Tumor Microenvironment

    Systems Biology of Stroma–Microbiome Interactions for Precision Therapy
    • 1st Edition
    • Ganji Purnachandra Nagaraju + 1 more
    • English
    The Pancreatic Tumor Microenvironment: Systems Biology of Stroma–Microbiome Interactions for Precision Therapy unites leading experts to integrate stromal biology and microbiome science into a single, translational roadmap for pancreatic cancer. It frames tumor progression and treatment resistance as emergent properties of an ecosystem, not isolated cells. The book surveys the composition and heterogeneity of the tumor microenvironment; cancer associated fibroblast plasticity; extracellular matrix and signaling dynamics; immune suppression; metabolic and hypoxic reprogramming; and gut/tumor associated microbiomes. Methodological chapters highlight single cell, spatial and multi omics approaches, experimental models, biomarkers, and clinical trial design, culminating in combination strategies and future directions. Readers gain a mechanistic, systems level synthesis that clarifies conflicting literature, prioritizes targets, and bridges basic, translational, and clinical domains—accelerating precision oncology and informing study design, patient stratification, and therapeutic combinations.
  • Robotic Drug Delivery with AI

    A Biomedical Engineering Approach
    • 1st Edition
    • Prabhnoor Bachhal + 3 more
    • English
    Robotic Drug Delivery with AI: A Biomedical Engineering Approach explores the cutting-edge integration of artificial intelligence and robotics in personalized drug delivery. Addressing the urgent need for precision medicine, this reference presents innovative approaches to tailor therapies to individual patients, enhancing treatment efficacy and reducing adverse effects. It fills a critical gap by linking engineering advances with clinical practice, offering researchers and practitioners a comprehensive resource. The book is organized into six parts covering foundational concepts of AI and robotics in healthcare, core technologies behind AI-driven drug delivery systems, clinical applications in chronic diseases and special populations, ethical and regulatory frameworks, and detailed case studies on cancer, diabetes, and nanomedicine. Each chapter includes learning objectives, definitions, case studies, and future directions to facilitate understanding and application. This volume benefits biomedical engineers, healthcare technologists, pharmaceutical researchers, and clinicians by providing a thorough exploration of AI-robotics integration in drug delivery. It equips readers to develop efficient, patient-specific treatment systems, navigate regulatory landscapes, and implement ethical AI solutions, advancing personalized healthcare worldwide.
  • Plant Development

    • 1st Edition
    • Volume 172
    • English
    Plant Development provides an overview of the fundamental processes that govern the growth, differentiation, and organization of plants throughout their life cycle. The book explores key developmental stages, from embryogenesis and seed germination to organ formation, flowering, and senescence, highlighting the genetic, molecular, cellular, and environmental factors that regulate these events. By integrating classical concepts with modern advances in developmental biology, the volume offers valuable insight into how plants establish form, adapt to their surroundings, and coordinate growth in response to internal and external signals. It serves as a useful resource for researchers, students, and professionals interested in plant biology, developmental mechanisms, and related fields.
  • 3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology

    Innovations for Personalized Oncology
    • 1st Edition
    • Ashok Kumar + 2 more
    • English
    3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology: Innovations for Personalized Oncology presents a comprehensive exploration of the transformative role of 3-D bioprinting and bio-generative engineering in modern medicine, with a specific focus on precision oncology. By examining innovative applications of these technologies, the book aims to bridge the gap between emerging scientific advancements and their practical implications in clinical settings. It delves into how patient-specific models of human tissues and organs can revolutionize drug testing, disease diagnostics, and personalized treatment plans, ultimately enhancing the quality of cancer care.Addressing critical challenges in oncology, this book highlights how 3-D bioprinting and bio-generative engineering can improve the accuracy of drug efficacy evaluations, reduce reliance on animal testing, and tackle the pressing issue of organ shortages for transplantation. Furthermore, it emphasizes the ethical considerations and regulatory challenges associated with integrating these technologies into everyday oncology practice, ensuring a balanced perspective on their adoption.
  • RNA-Binding Proteins Part A

    • 1st Edition
    • Volume 743
    • English
    Overall, this volume serves as a comprehensive methodological resource that integrates RNA-binding proteins, RNA metabolism, phase separation, and neurodegenerative disease mechanisms. As Volume 743 of the Methods in Enzymology series, RNA-Binding Proteins highlights recent advances in the field through chapters covering topics such as RNA-Binding Proteins: Structure, Function, and RNA Interactions; RNA Granules, Phase Separation, and Biomolecular Condensates; RNA Regulation in Cellular Physiology; RNA-Binding Proteins in Neurobiology and Neurodegeneration; RNA Processing, Editing, Splicing, and Decay; Non-Coding RNAs, Small RNAs, and RNA Therapeutics; and Experimental and Computational Methods for RNA–Protein Interaction Analysis. Collectively, these contributions provide valuable methodological and conceptual insights, making the volume highly relevant to researchers in molecular biology, neuroscience, RNA biology, and translational medicine.
  • The Kidney

    • 1st Edition
    • Volume 7
    • Ahmed El-Hashash + 1 more
    • English
    The Kidney, Volume Seven in the Stem Cell Innovation in Health and Disease series, explores the emerging potential of stem cell therapies in treating kidney diseases. With their natural regenerative and anti-inflammatory properties, stem cells offer a promising approach to restoring essential kidney functions and mitigating damage. This volume highlights how stem cell therapies may modulate immune responses, promote tissue repair, and replace damaged kidney cells, offering hope for chronic and acute renal conditions. Key developments include the injection of mesenchymal stem cells (MSCs) into damaged kidneys where they can differentiate into kidney cell types and aid in healing.In addition, urine-derived stem cells have also shown significant potential in improving kidney function in preclinical studies. Additionally, innovative techniques like incorporating MSCs into compact dialysis machines are explored, enabling delivery of pro-repair factors directly to the kidneys during blood filtration. While there are currently no FDA-approved stem cell treatments for kidney diseases, ongoing clinical trials aim to evaluate their safety and efficacy. This volume compiles cutting-edge research, discussing various cell sources, underlying mechanisms, observed therapeutic outcomes, and the practical challenges of clinical translation. By presenting a clear picture of current advances and future directions, this book serves as a vital resource for scientists, clinicians, and health innovators seeking to harness stem cell technology in nephrology.
  • Melanin-Concentrating Hormone

    From Metabolism to Sleep Disorders
    • 1st Edition
    • Jackson C. Bittencourt + 1 more
    • English
    Melanin-Concentratin... Hormone: From Metabolism to Sleep Disorders, the latest volume in the Molecular Mediators in Health and Disease series, offers a comprehensive understanding of this multifunctional peptide. The book covers a wide range of topics, including molecular biology of MCH, MCH in organ function, pharmacology, and MCH in disease. Recent developments in MCH imaging and pharmacological modulation are explored, along with the impact of MCH in psychiatric and neurodegenerative disorders and its role in the neuroimmunological modulation of vitiligo. Additionally, MCH is considered in the context of reproductive behavior, sleep, cognition, memory, and peripheral function.The book also explores MCH across various species such as humans, reptiles, non-primate mammals and teleosts. This is an ideal reference for researchers working with MCH across the fields of cell biology, molecular biology, pharmacology, neuroscience, endocrinology, and beyond.
  • The Complete Book of Coronary Artery Disease

    Anatomy, Physiology, Pathology, and Management
    • 1st Edition
    • Robert "Jay" Widmer
    • English
    The Complete Book of Coronary Artery Disease: Anatomy, Physiology, Pathology, and Management covers various essential aspects related to the anatomy, embryology, anomalies, physiology, pathology, imaging, and disease management of the coronary system. The book highlights both invasive and non-invasive imaging techniques, with a focus on coronary CTA and CT-guided PCI. Intravascular imaging methods such as IVUS and OCT are elaborated on in assessing coronary health, along with a section on coronary anomalies and their incidence, diagnosis, and clinical implications. Meanwhile, information on coronary physiology explores non-pathological functions and adaptations to stressors.Coronary ischemia assessment using physiological parameters and unresolved questions regarding symptoms are also fundamental to this volume. Further, this book details coronary atherosclerosis, including pathological processes and treatment options. A non-atherosclerotic coronary anatomy section addresses pathologies impacting coronary arteries in other ways. For professionals seeking consolidated information on an oft-overlooked topic, they need look no further than this book.
  • Congenital Adrenal Hyperplasia

    A Comprehensive Guide
    • 2nd Edition
    • Peter C. Hindmarsh + 1 more
    • English
    Congenital Adrenal Hyperplasia: A Comprehensive Guide, Second Edition provides a fully-illustrated edition that outlines the basics of CAH and its interrelation with hormones and bodily function, including updated content on the latest clinical research. A new chapter dedicated to gene therapy covers principles, current status, the latest research developments, and potential treatments for congenital adrenal hyperplasia. In addition, this new release updates patient profiles due to several new clinical studies in CAH for improved condition management, with practical information on how to deal with emergencies, medic alert emergency kits, emergency injection needles, handling illness, surgery, and more.In addition, new assays are incorporated for the analysis of pituitary and adrenal hormones for the determination of the disease. This new edition continues to be a vital reference to pediatric endocrinologists as well as primary care providers to help affected patients with an updated model of care and appropriate treatment. Patients and family members will continue to benefit from the new trend-forward information presented and will be empowered to approach their health care providers with the expectation of receiving individualized care and treatment of the disorder.
  • Introduction to Tactile Intelligence

    • 1st Edition
    • Shan Luo
    • English
    Introduction to Tactile Intelligence emphasizes the growing importance of tactile intelligence, essential for robots to interact effectively with the physical world. This book explores the science of tactile intelligence, equipping robots and intelligent machines with the ability to touch and feel the world, recognize textures, develop fine motor skills, and even convey emotions through physical contact. It anticipates a future where robots seamlessly integrate with the physical world through tactile intelligence and offers solutions for its development and application in various domains. This book is a good resource for students in robotics to experienced professionals, providing a solid foundation in tactile sensing, tactile-based control, and learning, as well as the integration of tactile data into broader robotic systems. This book provides valuable insights and practical guidance, and it serves as a reference for researchers at all stages of their careers in the dynamic field of tactile development and applications.
  • Correlative Light and Electron Microscopy VI

    • 1st Edition
    • Volume 213
    • English
    Correlative Light and Electron Microscopy VI presents current methods and applications in combining light microscopy and electron microscopy to study biological structures and processes with high spatial and temporal resolution. The volume highlights practical approaches for linking dynamic imaging with ultrastructural analysis, enabling researchers to investigate cells, tissues, and subcellular components in greater detail. Covering both established and emerging techniques, this book serves as a useful resource for scientists working in cell biology, structural biology, imaging, and related biomedical fields.
  • Geostatistical Approaches to Environmental and Public Health Issues

    • 1st Edition
    • Deepak Kumar + 4 more
    • English
    Geostatistical Approaches to Environmental and Public Health Issues discusses how geostatistical techniques can be leveraged to better understand and respond to pressing environmental and public health challenges. The book showcases how techniques like kriging, spatial regression, Bayesian modeling, and space-time analysis offer powerful, nuanced insights into these issues. Emphasizing stochastic, non-deterministic approaches, it highlights the importance of modeling uncertainty in both environmental and health domains. Through case studies and research-driven chapters, sections demonstrate how integrating geospatial and statistical methods can enhance our understanding of where, why, and how events occur—ultimately improving the precision of health interventions and environmental policies.By aligning cutting-edge statistical approaches with the geospatial dimensions of health and environmental data, this book fills a critical gap in the literature and supports more targeted, data-driven decision-making in the face of global uncertainty. It bridges methodological innovation with applied research, making it an essential resource for scientists, policymakers, and public health practitioners.
  • Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer

    • 1st Edition
    • Afsar Naqvi + 1 more
    • English
    Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer explores the critical role of noncoding RNAs in immune-mediated diseases and cancers, providing an essential resource on their diagnostic and therapeutic potential. The book contributes valuable insights into the pathobiology of noncoding RNAs and their application in various diseases, delving into the latest research on noncoding RNAs, including their mechanisms, interactions, and roles in disease. In addition, it examines how noncoding RNAs influence immune responses, inflammation, and cancer progression. With a focus on both diagnostic and therapeutic applications, this book highlights the potential of noncoding RNAs as biomarkers and therapeutic targets. Across comprehensive chapters, the book covers a wide range of topics, including the role of virus-encoded microRNAs in immune evasion, the therapeutic aspects of non-coding RNA in hepatocellular carcinoma, the impact of microRNAs in periodontal inflammation, and the involvement of miRNAs and lncRNAs in regulating the tumor microenvironment in HCC. Other chapters explore the functions and clinical value of tumor-derived exosomes and miRNAs in cancer immune response, the interaction of noncoding RNA in cancer metastasis, and a panorama of non‐coding RNA in prostate cancer. This book is an invaluable resource for basic science researchers in the noncoding RNA field, cancer biologists, immunologists and RNA biologists interested in the latest advancements in noncoding RNA research.
  • Shared Research Resources

    Best Practices in Management and Administration
    • 1st Edition
    • Joshua Z. Rappoport + 1 more
    • English
    Shared Research Resources: Best Practices in Management and Administration brings together best practices and case studies from research institutions around the world. Covering all areas of management, with examples and applications specific to the research environment, this is the perfect reference to build managerial skills. The first part is dedicated to introducing Shared Research Resources (SRR) management. The second part covers all aspects of staffing. Part three contains complete coverage of operations, including service development, instrument procurement, marketing, management software, customer support, safety, maintenance and repair. Part four is dedicated to fiscal management, budgeting, and reporting.Part five covers strategic management. Part six is devoted to the sustainability of the core facility. The final part covers assessment, including annual reports, program reviews, and audits. This book is a complete reference targeted at SRR managers and staff who need to keep updated with current best practices and case studies. It is also important reading for research institution managers and function leaders.
  • Innovation in Emergency Medicine

    Technology Development and Commercialization Handbook
    • 1st Edition
    • Nancy Patterson + 3 more
    • English
    Innovation in Emergency Medicine: Technology Development and Commercialization Handbook is a step-by-step guide to emergency medicine technology innovation reflecting recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads engineers, clinicians, students, researchers, and entrepreneurs through a clear process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. This new volume in the Clinical and Medical Innovation Series will be of interest to every biomedical engineer and those working in emergency medicine who has ever had a good idea for an invention but does not know where and how to start bringing it to the bedside.
  • Electrocardiography of Laboratory Animals

    • 3rd Edition
    • Meg M. Sleeper + 1 more
    • English
    Electrocardiography of Laboratory Animals, Third Edition, provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book begins with the fundamental principles of electrocardiography and its applications in drug safety evaluation but then covers electrocardiography in a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees.Addition... it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. It is an essential resource for biological and medical researchers, veterinarians, zoologists, and students.
  • Introduction to Bioinformatics and Machine Learning

    • 1st Edition
    • Milana Frenkel-Morgenstern
    • English
    Introduction to Bioinformatics and Machine Learning provides comprehensive instruction in modern computational biology by integrating bioinformatics, genomics, artificial intelligence, and machine learning into a unified learning framework. The book bridges the gap between biological data analysis and computational methods, covering fundamental concepts in molecular biology and bioinformatics together with practical applications of machine learning to genomics, transcriptomics, proteomics, microbiome research, structural biology, NGS technologies, liquid biopsy, cancer genomics, and precision medicine. Readers are introduced to DNA and RNA sequencing technologies, genome assembly, sequence alignment, variant discovery, gene expression analysis, fusion gene detection, protein structure prediction, biological databases, statistical analysis, explainable artificial intelligence, and predictive modeling. Throughout the book, real-world biomedical case studies demonstrate how computational methods are transforming modern biological and clinical research; and both bioinformatics and machine learning are addressed in a coherent and accessible manner, emphasizing practical problem-solving, reproducible computational workflows, and biological interpretation of results.Designed for upper-level undergraduate students, graduate students, and researchers, this book serves as both a classroom textbook and practical assignments for those working at the interface of biology, computer science, medicine, and data science.
  • Federated Intelligence in Medicine

    AI-Driven Robotics for Secure and Intelligent Healthcare Systems
    • 1st Edition
    • Manisha Guduri + 3 more
    • English
    Federated Intelligence in Medicine: AI-Driven Robotics for Secure and Intelligent Healthcare Systems explores the rapidly evolving field where medical robotics intersects with cutting-edge artificial intelligence and secure data-sharing technologies. Covering a comprehensive range of topics, the book begins with foundational knowledge in medical robotics and Generative AI, progressing to advanced concepts such as federated learning and architectural modeling tailored for AI-driven robotic systems. Readers will explore algorithms enhancing surgical robotics, remote robotic surgeries, and human-robot interaction. The text also tackles AI-driven diagnostic robots, privacy preservation through homomorphic encryption, and differential privacy and emerging medical imaging techniques integrated with robotics.Later chapters examine the synergy of large language models, agent AI, and edge AI with robotic technologies, providing both theoretical frameworks and practical case studies that illuminate real-world applications and challenges. This book is an invaluable resource for researchers and academicians engaged in artificial intelligence, robotics, and medical technology. It also serves undergraduate and graduate students in Biomedical Engineering, Electronics and Electrical Engineering, and Computer Science and Engineering.
  • Neurogenetic Therapies

    Advancements in Treating Nervous System Disorders
    • 1st Edition
    • Ashutosh Pareek + 4 more
    • English
    Neurogenetic Therapies: Advancements in Treating Nervous System Disorders offers a comprehensive resource on the latest gene therapy techniques and their applications in treating neurological disorders. The book delves into various gene therapy methods, including genomic DNA-based therapies, vector-mediated delivery, and RNA interference-based gene silencing. It explores the use of these techniques in treating conditions such as Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and Duchenne muscular dystrophy. Key topics include the molecular and genetic basis of nervous system disorders, the role of epigenetics, and the development of stem cell and genome editing therapies.With contributions from leading experts, the book also addresses regulatory and ethical considerations in gene therapy, providing a balanced perspective on the challenges and opportunities in this rapidly evolving field. Case studies and practical examples illustrate successful gene therapy treatments, offering valuable insights into translating research into clinical practice. This book is an essential resource for students, researchers, and scientists in neurogenetics, neurology, and molecular biology, as well as clinicians interested in the mechanisms and treatment of neurodegenerative diseases.
  • Applications of Microfluidics Device Technology

    • 1st Edition
    • Volume 227
    • English
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.
  • LGBTQ+ Access to Inflammatory Bowel Disease Healthcare

    Current Trends and Considerations
    • 1st Edition
    • Lesley Dibley + 1 more
    • English
    LGBTQIA+ Access to Inflammatory Bowel Disease Healthcare: Current Trends and Considerations illuminates the unique medical, surgical, and mental health issues faced by LGBTQIA+ patients, providing clinicians with the knowledge to understand why these issues arise and how they can be effectively addressed. This crucial resource aims to elevate awareness among healthcare providers and commissioners about the need for gender- and identity-affirming care. As societal recognition of LGBTQIA+ rights grows, this book steps into the unexplored terrain of LGBTQIA+ healthcare and IBD, addressing both medical complexities and the social and political dimensions of care. The book opens with an introduction to the significance of LGBTQIA+ access to healthcare and the necessity for clinician awareness. It includes contributions from leading experts and a comprehensive glossary of relevant LGBTQIA+ terms. Key topics covered are the socio-cultural and political history influencing healthcare access, the impact of stigma on healthcare utilization and adherence, and specific medical, surgical, and mental health considerations for transgender patients with IBD. The text also covers gender- and identity-affirming practices, advocating for effective patient-provider communication and supportive healthcare environments, even in challenging settings. The concluding chapters assess the progress made and the journey ahead in LGBTQIA+ IBD care. Designed for clinicians and healthcare providers, this book serves as an indispensable reference, consolidating essential contemporary evidence into a single, accessible resource. Whether you are a gastroenterologist, surgeon, mental health professional, or healthcare researcher, this book offers the insights and tools necessary to deliver inclusive and effective care, keeping pace with the evolving healthcare advocacy and equality landscape.
  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1st Edition
    • Riccardo De Robertis
    • English
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.
  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.
  • Hypoxia-induced Tumor Heterogeneity and Immune Evasion

    Clinical Interventions
    • 1st Edition
    • Benjamin Bonavida + 1 more
    • English
    Hypoxia-induced Tumor Heterogeneity and Immune Evasion: Clinical Interventions explores how hypoxic stress within the tumor microenvironment drives cancer progression, immune escape, and resistance to therapy. This volume integrates foundational and cutting-edge insights into tumor biology, immunology, and therapeutic innovation. The book is structured into five parts, covering tumor heterogeneity, hypoxia-driven mechanisms, immune evasion, clinical diagnostics, and future directions. It brings together global experts to examine how hypoxia shapes tumor evolution, alters immune responses, and influences treatment outcomes. Topics include metabolic reprogramming, angiogenesis, immune suppression, and hypoxia-targeted therapies, with emphasis on translational relevance. This resource benefits researchers, clinicians, and advanced students by offering a comprehensive, up-to-date synthesis of a rapidly evolving field. It supports deeper understanding of tumor complexity and equips readers with knowledge to inform experimental design, clinical strategies, and therapeutic development in oncology.