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Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies

  • 1st Edition - May 26, 2026
  • Latest edition
  • Editors: Shuvomoy Banerjee, Dhiraj Bhatia
  • Language: English

Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies addresses the critical challenge of cancer chemoresistance, synthesizing insigh… Read more

Description

Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies addresses the critical challenge of cancer chemoresistance, synthesizing insights from cancer biology, molecular biology, biotechnology, and nanotechnology. The book explores the complex mechanisms underlying drug resistance, including alterations in key signaling pathways and the tumor microenvironment's role in cancer cell survival. It highlights advancements in drug delivery technologies, such as nanomedicine and biomimetic strategies, which enhance drug targeting and minimize off-target effects. The integration of techniques like CRISPR-Cas9 and artificial intelligence in developing next-generation therapies is also emphasized.

For an academic audience, this book serves as an essential resource to foster interdisciplinary collaboration in cancer research. It equips researchers, clinicians, and industry professionals with the knowledge needed to navigate the evolving landscape of cancer therapeutics, addressing critical challenges in drug delivery and chemoresistance to improve patient outcomes.

Key features

  • Combines knowledge from cancer biology, molecular biology, biotechnology, and nanotechnology to provide a comprehensive understanding of chemoresistance and innovative drug delivery systems
  • Showcases the latest advancements in drug delivery methods, including nanomedicine and biomimetic strategies, emphasizing their potential to enhance therapeutic efficacy and minimize off-target effects
  • Presents solutions to overcome cancer chemoresistance, equipping researchers, clinicians, and industry professionals with essential knowledge to navigate the evolving landscape of cancer therapeutics

Readership

Researchers and Academics in oncology, cancer biology, molecular biology, and drug development

Table of contents

1 Exploring chemoresistance mechanisms and innovative drug delivery approaches in effective cancer therapy
Khushbu Priyadarshi, Tata Santosh Rama Bhadra Rao

2 Molecular interplay of hypoxia, aberrant angiogenesis, and immune suppression in cancer chemoresistance
Nidhi Nagariya, Komal N. Rawal, Jyoti V. Thaikoottathil

3 Impact of hypoxia, angiogenesis, and immunosuppression in chemoresistance
Padavala Ashrai, Shaikh Zishan, Kotnis Ashwin

4 Design and applications of smart biomaterials for anticancer drug delivery systems
Dhyanam Raval, Khush Patel, Shambhu Yadav, Pankaj Yadav

5 Revolutionizing precision oncology: Combating chemoresistance with nanorobotics
Keshaw Ram Aadil, Khushboo Bhange, Gita Mishra, Raj Kumar

6 Advanced drug delivery strategies: Nanoparticles, liposomes, dendrimers, and smart biomaterials
Divya Khatri, Bazil Gulzar Wani, Maroosha Mir, Anjali Chauhan, Deepika Chauhan

7 Epigenetic modulations in cancer chemoresistance: Harnessing nanotechnology for targeted therapy
Priya Sharma, Versha Sharma, Ravinesh Mishra, Bhartendu Sharma, Sandeep Goswami

8 Advancements in cancer immunotherapy: Targeting the tumor immune microenvironment (TIME)
Smeeta Sadar, Satish Polshettiwar, Chitra Phalak, Vedika Walhekar, Samiksha Chaher, Vishwambhari Lagad

9 Near-infrared responsive photothermal-immunotherapy for overcoming chemoresistance in cancer therapy
Namratha Parthasarathy, Karthikeyan Laxmanan, Yasothamani Vellingiri, Raju Vivek, Mukesh Dhanka

10 Combating chemoresistance through RNA-based therapeutic approaches: A mechanistic insight
Dhruvi Dipakbhai Patel, Drashti P. Sanghvi, Qiliang Cai, Shuvomoy Banerjee

11 Therapeutic potential of drug repurposing in reversing chemoresistance
Vivek Panwar, Aarushi Rana

12 Ion channels in chemoresistance: A mechanistic overview and CRISPR-based therapeutic strategies
Vaibhavi Sharma, Poulami Dutta, Aakansha Aaryan, Arundhati Ray, Anand K. Tiwari, Juni Banerjee

13 CRISPR/Cas9 and gene editing approaches as a solution for chemoresistance
Gurpreet Kaur, Priyanka Rani, Damandeep Kaur, Anuradha Kumari, Juni Banerjee

14 Clinical applications and emerging challenges of novel drug delivery systems
Dipali M. Dhoke, Satish Polshettiwar

15 Exosome and extracellular vesicle-based therapeutics to overcome cancer chemoresistance
Pranav Seth, Priyanka Sharma

16 Preclinical strategies for investigating drug delivery platforms
V. Kumar, G. Mustafa, R. Singh, S.K. Shukla, Z. Ahmed

17 Artificial intelligence and machine learning approaches in rational drug design to overcome cancer chemoresistance
Sanjana Mishra, Prekshi Garg, Anshul Tiwari, Prachi Srivastava

18 Chemoresistance in modern oncology: A multilayered network of signaling, plasticity, and tumor microenvironmental interactions
Shuvomoy Banerjee, Dhiraj Bhatia

Product details

  • Edition: 1
  • Latest edition
  • Published: May 26, 2026
  • Language: English

About the editors

SB

Shuvomoy Banerjee

Dr. Shuvomoy Banerjee is an accomplished academic and researcher with extensive experience as an editorial board member for several reputable journals, including Reviews in Medical Virology, and as an associate editor for the IAR University Journal. He holds a Ph.D. in cancer biology from Bose Institute, Kolkata, and has post-doctoral research experience at the University of Pennsylvania and Beckman Research Institute. Currently an Assistant Professor at the Institute of Advanced Research, Gandhinagar, Dr. Banerjee specializes in cancer immunology and tumor virology. His prolific contributions include numerous publications in high-impact journals. He has led multiple extramural research projects funded by organizations such as the Science and Engineering Research Board (SERB) and the Gujarat State Biotechnology Mission. His active participation in various scientific organizations underscores his credibility and thought leadership in the field of cancer research.

Regenerate response
Affiliations and expertise
Institute of Advanced Research (IAR), India

DB

Dhiraj Bhatia

Dr. Dhiraj Bhatia, an associate professor at IIT-Gandhinagar, specializes in DNA nanotechnology, chemical biology, and drug delivery systems. With a Ph.D. from NCBS-TIFR and postdoctoral work including an HFSP fellowship at Institut Curie, he has pioneered research in structural DNA nanotechnology for biomedical applications. His publications in high-impact journals like ACS Nano, Nature Nanotechnology, and Angewandte Chemie showcase his expertise. His work on programmable DNA nanodevices, hydrogels, and targeted drug delivery addresses critical challenges such as cancer chemoresistance. Recognized with awards like the Merck Young Scientist Award and INYAS-INSA Membership, Dr. Bhatia is also an experienced reviewer and mentor, actively organizing interdisciplinary conferences
Affiliations and expertise
Indian Institute of Technology (IIT), India