Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

Books Journals

A Beginner's Guide to Data Agglomeration and Intelligent Sensing

1st Edition
February 19, 2020
Amartya Mukherjee + 2 more
English
Paperback
9 7 8 0 1 2 8 2 0 3 4 1 5
eBook
9 7 8 0 1 2 8 2 0 3 4 5 3

A Beginners Guide to Data Agglomeration and Intelligent Sensing provides an overview of the Sensor Cloud Platform, Converge-casting, and Data Aggregation in support of intelligent sensing and relaying of information. The book begins with a brief introduction on sensors and transducers, giving readers insight into the various types of sensors and how one can work with them. In addition, it gives several real-life examples to help readers properly understand concepts. An overview of concepts such as wireless sensor networks, cloud platforms, and device-to-cloud and sensor cloud architecture are explained briefly, as is data gathering in wireless sensor networks and aggregation procedures. Final sections explore how to process gathered data and relay the data in an intelligent way, including concepts such as supervised and unsupervised learning, software defined networks, sensor data mining and smart systems.

Inflammatory Disorders - Part B

1st Edition
Volume 120
February 19, 2020
Rossen Donev
English
Hardback
9 7 8 0 1 2 8 2 1 3 2 2 3
eBook
9 7 8 0 1 2 8 2 1 3 2 3 0

Inflammatory Disorders - Part B, Volume 120 explores inflammation in the immune system and how the body’s own cells or tissues may cause abnormal inflammation, thus resulting in chronic pain, redness, swelling, stiffness, and damage to normal tissues. Chapters in this updated volume include Proteins in monogenic autoinflammatory disorders, Virulence factors and their roles in periodontal disease pathogenesis, Role of Heat shock proteins in Inflammatory disorder Rheumatoid Arthritis, Novel targeted therapies for Crohn's disease: Recent progress and future perspectives, Dietary plant flavonoids in prevention of obesity and diabetes, Small RNAs in allergic diseases, Inflammation and inflammasome during ageing and age-related diseases, and more.

Genome Engineering via CRISPR-Cas9 System

1st Edition
February 18, 2020
Vijai Singh + 1 more
English
Paperback
9 7 8 0 1 2 8 1 8 1 4 0 9
eBook
9 7 8 0 1 2 8 1 8 1 4 1 6

Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields.

BEST

1st Edition
February 18, 2020
Lorena Infante Lara + 2 more
English
Paperback
9 7 8 0 1 2 8 2 0 7 5 9 8
eBook
9 7 8 0 1 2 8 2 0 8 8 9 2

BEST: Implementing Career Development Activities for Biomedical Research Trainees provides an instructional guide for institutions wanting to create, supplement or improve their career and professional development offerings. Each chapter provides an exclusive perspective from an administrator from the 17 Broadening Experiences in Scientific Training (BEST) institutions. The book can aid institutions who train graduate students in a variety of careers by teaching faculty and staff how to create and implement career development programming, how to highlight the effectiveness of offerings, how to demonstrate that creating a program from scratch is doable, and how to inform faculty and staff on getting institutional buy-in. This is a must-have for graduate school deans and faculty and staff who want to implement and institutionalize career development programing at their institutions. It is also ideal for graduate students and postdocs.

Protein Homeostasis Diseases

1st Edition
February 13, 2020
Angel L. Pey
English
Paperback
9 7 8 0 1 2 8 1 9 1 3 2 3
eBook
9 7 8 0 1 2 8 1 9 1 3 3 0

Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-functi... and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders.

Aquaporin Regulation

1st Edition
Volume 112
February 13, 2020
Gerald Litwack
English
Hardback
9 7 8 0 1 2 8 2 0 8 0 9 0
eBook
9 7 8 0 1 2 8 2 0 8 1 0 6

Aquaporin Regulation, Volume 112, the latest release in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters highlighting Perspectives on the evolution of aquaporin superfamily, Structure and dynamics of aquaporin-1, Selectivity and Transport in Aquaporins from Molecular Simulation Studies, Aquaporin regulation in metabolic organs, Phosphorylation of human AQP2 and its role in trafficking, Regulation of Aquaporin-2 by RNA Interference, Aquaporin Regulation: Lessons from Secretory Vesicles, CFTR Regulation of Aquaporin-mediated Water Transport, Glucocorticoid Gene Regulation of Aquaporin-7, and much more.

Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C

1st Edition
Volume 633
February 10, 2020
Arun K. Shukla
English
Hardback
9 7 8 0 1 2 8 1 9 1 2 8 6
eBook
9 7 8 0 1 2 8 1 9 1 2 9 3

Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C, Volume 633, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial. This release includes sections on Next generation probes for molecular imaging in cells, Competitive binding assay for biotin and biotin derivatives, based on avidin and biotin-4-fluorescein... Converting avidin to bind ligands other than biotin, especially steroids, Chemoenzymatic Labeling Strategy, Engineered Siderophores, Small molecules to inhibit bacterial population behavior, NMR tube bioreactor, Small molecule controlled RAS activation system, Small molecule regulated Cas9, the Design and application of synthetic receptors, and much more.

Second Generation Cell and Gene-Based Therapies

1st Edition
February 7, 2020
Alain Vertes + 3 more
English
Hardback
9 7 8 0 1 2 8 1 2 0 3 4 7
eBook
9 7 8 0 1 2 8 1 2 0 3 3 0

Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept of therapeutic cells (stem cells, genes, etc.), beyond the concept of vaccines, is reaching clinical trial, with mounting confidence in the safety and efficacy of these products. Nonetheless, numerous incremental technical advances remain to be achieved. Thus, this volume highlights the possible R&D paths, which will ultimately facilitate clinical delivery of cutting edge curative products.The next waves of innovation are reviewed in depth for hematopoietic stem cells, mesenchymal stem cells, tissue engineering, CAR-T cells, and cells of the immune system, as well as for enabling technologies such as gene and genome editing. Additionally, deep dives in product fundamentals, history of science, pathobiology of diseases, scientific and technological bases, and financing and technology adoption constraints are taken to unravel what will shape the cytotherapy industry to the horizon 2025 and beyond. The outcome is not simply a scientific book, but a global perspective on the nascent field combining science, business, and strategic fundamentals.

100 Years of Human Chorionic Gonadotropin

1st Edition
February 7, 2020
Laurence A. Cole + 1 more
English
Paperback
9 7 8 0 1 2 8 2 0 0 5 0 6
eBook
9 7 8 0 1 2 8 2 1 6 0 9 5

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world’s leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule.

Handbook of Research on Blockchain Technology

1st Edition
February 4, 2020
Saravanan Krishnan + 5 more
English
Paperback
9 7 8 0 1 2 8 1 9 8 1 6 2
eBook
9 7 8 0 1 2 8 2 0 4 1 5 3

Handbook of Research on Blockchain Technology presents the latest information on the adaptation and implementation of Blockchain technologies in real world business, scientific, healthcare and biomedical applications. The book's editors present the rapid advancements in existing business models by applying Blockchain techniques. Novel architectural solutions in the deployment of Blockchain comprise the core aspects of this book. Several use cases with IoT, biomedical engineering, and smart cities are also incorporated. As Blockchain is a relatively new technology that exploits decentralized networks and is used in many sectors for reliable, cost-effective and rapid business transactions, this book is a welcomed addition on existing knowledge. Financial services, retail, insurance, logistics, supply chain, public sectors and biomedical industries are now investing in Blockchain research and technologies for their business growth. Blockchain prevents double spending in financial transactions without the need of a trusted authority or central server. It is a decentralized ledger platform that facilitates verifiable transactions between parties in a secure and smart way.

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Biochemistry biophysics

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