Skip to main content
Elsevier

Mechanisms of Cell Death and Opportunities for Therapeutic Development

  • 1st Edition - October 26, 2021
  • Latest edition
  • Editor: Diaqing Liao
  • Language: English

Mechanisms of Cell Death and Opportunities for Therapeutic Development, volume four in the Perspectives in Translational Cell Biology series, offers content for professors, stud… Read more

Description

Mechanisms of Cell Death and Opportunities for Therapeutic Development, volume four in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. The book covers fundamental mechanisms, ranging from different forms of cell death and drug development, to efforts for treating disease, providing a valuable resource for readers interested in understanding cell death and relevant translational research. The book's editor, Diaqing Liao, has over twenty years’ experience teaching topics of cell death.

Key features

  • Provides a comprehensive overview of current knowledge on the process of apoptosis, its potential role in health and disease, and a discussion of potential alternative forms, such as autophagy
  • Covers fundamental mechanisms and relevant translational research

Readership

In the fields of biomedical research and drug discovery and development including graduate students, postdocs and faculty in academia and scientists in research and development in biotech and pharmaceutical industry

Table of contents

1. An overview of cell death in health and disease

2. Cell death:machinery and regulation

3. Molecular mechanisms of cell death: A brief overview

4. Major methods and technologies for assessing cell death

5. Proteotoxicity and endoplasmic reticulum stress-mediated cell death

6. Protein phase separation in cell death and survival

7. Therapeutics targeting the BCL-2 pathway

8. Ferroptosis: lipids, iron, cellualar defese mechanisms and opportunities for drug development

Product details

  • Edition: 1
  • Latest edition
  • Published: October 26, 2021
  • Language: English

About the editor

DL

Diaqing Liao

Diaing Liao has extensive experience, over twenty years, in research and teaching related to topics of cell death. He has been the course director of a graduate level course “Apoptosis” for over ten years at University of Florida. Dr. Liao’s research has focused on mechanisms underlying cancer biology, epigenetic regulation and drug discovery. His lab has contributed numerous original publications on cellular and viral regulators of cell death and signalling pathways.
Affiliations and expertise
Department of Anatomy and Cell Biology, School of Medicine, University of Florida, FL, USA

View book on ScienceDirect

Read Mechanisms of Cell Death and Opportunities for Therapeutic Development on ScienceDirect