Books in Molecular biology cellular biology and genetics

Plant-Based Drug Discovery

1st Edition
September 1, 2025
Akhileshwar Kumar Srivastava + 2 more
English
Paperback
9 7 8 0 4 4 3 3 1 6 9 8 2
eBook
9 7 8 0 4 4 3 3 1 6 9 9 9

Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

Biology of Fatty Acids

1st Edition
September 1, 2025
E. P. Meran Keshawa + 1 more
English
Paperback
9 7 8 0 4 4 3 3 3 2 9 6 8
eBook
9 7 8 0 4 4 3 3 3 2 9 7 5

Biology of Fatty Acids: Biochemical, Nutritional, and Pharmacological Functions offers an in-depth exploration of the vital roles fatty acids play in human health. From their influence on metabolism and immune functions to their potential in disease prevention and treatment, this book covers a wide range of topics. With contributions from leading experts, it examines the latest research on fatty acids in nutrition, emerging plant-based sources, and their pharmacological potential in treating conditions like neurodegenerative diseases and cancer. A must-read for scientists, healthcare professionals, and anyone interested in the transformative impact of fatty acids on human health.

New Developments in Redox Biology

1st Edition
September 1, 2025
Atala Bihari Jena + 1 more
English
Paperback
9 7 8 0 4 4 3 4 3 8 8 4 4
eBook
9 7 8 0 4 4 3 4 3 8 8 5 1

New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a comprehensive exploration of the influence of the redox system and the complex relationships between oxidative stress, biological development, health and disease. Divided into three sections, it explores the role of the redox system across developmental biology, non-communicable diseases, and infectious diseases. The first section includes chapters exploring oxygen availability in embryonic development, the influence of stress factors and intra-cellular signalling during embryogenesis, and how stem cells maintain homeostasis under oxidative stress. Section two considers topics such as the origin of cancer stem cells related to hypoxia, redox-related biomarkers in tumorigenesis and metabolic disorders, and the role of oxidation and reduction systems in autoimmune disorders and neurodegeneration. The final section focuses on redox regulation in infectious illness and includes chapters on redox biomarkers in host-pathogen interaction, the role of redox control in zoonotic diseases, and the significance of hypoxia on the ability of microbial pathogens to invade the gut. Antiviral drugs and the use of redox regulation in their mechanism of action is also explored. New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a multidisciplinary approach to the topic, providing valuable insights to those seeking to expand their expertise in redox biology and its implications for human health and disease. In particular, researchers and advanced students working across molecular biology, cell biology, biochemistry, developmental biology and related fields will find this book useful.

Epigenetics Methods

2nd Edition
August 31, 2025
Trygve O. Tollefsbol
English
Paperback
9 7 8 0 4 4 3 2 6 7 5 9 8
eBook
9 7 8 0 4 4 3 2 6 7 6 0 4

Epigenetics Methods, Second Edition offers an extensive overview of the tools that enhance translational epigenetics studies. This edition includes updated and revised chapters, along with newly added topics such as MALDI-TOF-MS for analyzing DNA methylation and the RIP assay for lncRNA binding. Specialists provide step-by-step guidance on methods used to study various epigenetic mechanisms. The book covers both fundamental and advanced techniques, making it an essential resource for researchers in this dynamic field. In addition to DNA methylation and histone modification techniques, the book also explores chromatin evaluation, enzyme analyses, and non-coding RNAs as epigenetic modulators.New chapters discuss recent advancements like single-cell epigenomics, epigenetic editing, and computational epigenetics. The volume addresses reproducibility issues and offers consensus-driven methods to unify approaches across experiments and labs. This edition is a vital reference for understanding and employing cutting-edge epigenetics methods.

Harnessing Genomic Tools for Crop Improvement

1st Edition
August 10, 2025
Lakshmi Narayana R. Vemireddy + 2 more
English
Paperback
9 7 8 0 4 4 3 2 9 2 8 1 1
eBook
9 7 8 0 4 4 3 2 9 2 8 2 8

In the rapidly evolving landscape of crop genetics, the book, Harnessing Genomic Tools for Crop Improvement is an essential resource designed for researchers, students, and professionals seeking to leverage bioinformatics tools for precision breeding. This comprehensive manual provides step-by-step guidance on utilizing molecular data derived from genetics and breeding experiments, offering hands-on instructions for key software applications in genetic diversity analysis, QTL mapping, genome-wide association mapping, haplotype analysis and genomic selection.Beyond technical tutorials, the book explores cutting-edge bioinformatics tools such as sequence databases, BLAST, primer designing, and sequence alignment, ensuring users gain a holistic understanding of genomics-driven crop improvement. Definitions, terminology clarifications, and interpretation of the results help bridge the gap between theory and application, simplifying complex analyses.Whether you are a novice or an experienced researcher, this book equips you with the skills to analyze and apply genomic data effectively, making it an invaluable asset for transforming geneticists into genomicists in both plant and animal sciences.

Targeted Protein Degradation Technologies

1st Edition
August 6, 2025
Jiangjiang Qin + 2 more
English
Paperback
9 7 8 0 4 4 3 2 1 8 1 6 3
eBook
9 7 8 0 4 4 3 2 1 8 1 7 0

Targeted Protein Degradation Technologies provides a thorough overview of targeted protein degradation from the latest developments in the field to potential therapeutic applications. The book begins with an introduction to the mechanisms of protein degradation followed by a section covering both protease-mediate degradation and lysosome-mediate degradation. A range of cutting-edge technologies are covered, including PROTAC, AbTAC, molecular glues, hydrophobic tagging, LYTAC, GlueTAC and AUTAC. Degraders of specific proteins are then investigated, including signal transduction receptors, membrane proteins, and transcription factor degraders.The book closes with a section on the clinical applications of targeted protein degradation and a look at future perspectives. It is a useful resource to those in the fields of molecular biology, cell biology, and related areas working with protein degradation and the development of therapeutic technologies in this arena.

Metagenomics for Microbiology

2nd Edition
August 4, 2025
Jacques Izard + 1 more
English
Paperback
9 7 8 0 4 4 3 2 2 3 7 6 1
eBook
9 7 8 0 4 4 3 2 2 3 7 7 8

Metagenomics for Microbiology, Second Edition unveils the intricate and diverse world of microbial communities, emphasizing their critical roles in health, disease, and ecosystem functionality. This updated edition addresses the significant challenges in the field and introduces promising approaches to make metagenomics research more feasible. Through comprehensive revisions and over five new chapters, readers are equipped with the latest research data and analyses, advancing their understanding of microbial principles. Notably, this edition provides a robust foundation for the design and analysis of omics studies, focusing on technological underpinnings and practical applications. It remains an essential resource for characterizing microbial consortia.

Methods in Biomolecular Modelling

1st Edition
August 3, 2025
Thomas W. Keal
English
eBook
9 7 8 0 4 4 3 2 2 0 4 0 1

Methods in Biomolecular Modelling, Volume Two in the series, considers modeling methods with relevance to the study of biomolecular systems, including the workhorse of classical molecular dynamics and related techniques, areas where electronic structure methods find use, the higher length scales achievable through coarse grained and mesoscale methods, and combinations of scales. Applicability of methods is then illustrated with a wide range of biomolecular modeling research topics drawn from current research. Throughout the text, practical considerations of research are emphasized, including sourcing of structural data, scalability of methods on HPC systems, and linking of computation to experiment.Part I introduces a range of modeling techniques used for biomolecular simulation, explaining the fundamental principles of each and the research areas to which they are applicable. The strengths and weaknesses of each method are outlined, along with their real-world performance on current computing resources and future trends. Part II looks at a range of application areas, with case studies illustrating the methods that can be used to investigate biomolecular systems in these areas.

The Emerging Genomic Landscape of Complex Immune-Mediated Traits

1st Edition
Volume 114
August 1, 2025
Juliana Miranda Cerqueira
English
Hardback
9 7 8 0 4 4 3 2 2 4 1 5 7
eBook
9 7 8 0 4 4 3 2 2 4 1 6 4

The Emerging Genomic Landscape of Complex Immune-Mediated Traits, Volume 114 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Unraveling the Interplay of Genetic Variants and Epigenetic Signatures in Complex traits, Crosstalk between T Cell Gene Regulation and Intestinal Epithelial Cells: Insights into Mucosal Immunity, Understanding the link between regulatory RNA regions and genomic variation with coeliac disease, Interplay Between the Host Genome, Autoimmune Disease and Infection, and Organoids and gut-on-chip as powerful tools to model the genetics of intestinal mucosal inflammation.

Immuno-oncology and Immunotherapy Part D

1st Edition
Volume 196
August 1, 2025
Lorenzo Galluzzi + 2 more
English
Hardback
9 7 8 0 4 4 3 2 9 6 1 8 5
eBook
9 7 8 0 4 4 3 2 9 6 1 9 2

Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Investigating the endothelial-immune axis in cancer, Establishing Tyro3, Axl, and Mertk Chinese Hamster Ovary (CHO) Reporter Cell Lines for Cancer Immunology and Therapeutic Applications, Amino acid analog-based labelling of the immunomodulatory cancer secretome, Human and mouse iNKT cell expansion and engineering with viral vectors, Next-generation deconvolution of the tumor microenvironment with omnideconv, and much more.Additional sections cover Comprehensive prediction of tumor neoantigens with NextNEOpi, Ex vivo profiling of organotypic tumor spheroids in 3D microfluidic culture, A flow cytometry-based assay for evaluation of T cell activation and degranulation in coculture systems, An adenosine production assay suitable for 2D and 3D cancer cell culture, Determination of lactate in the tumor interstitial fluid, Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils, Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells, and much more.

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