Books in Molecular biology cellular biology and genetics

Metagenomics for Microbiology

2nd Edition
August 4, 2025
Jacques Izard + 1 more
English
Paperback
9 7 8 0 4 4 3 2 2 3 7 6 1
eBook
9 7 8 0 4 4 3 2 2 3 7 7 8

Metagenomics for Microbiology, Second Edition unveils the intricate and diverse world of microbial communities, emphasizing their critical roles in health, disease, and ecosystem functionality. This updated edition addresses the significant challenges in the field and introduces promising approaches to make metagenomics research more feasible. Through comprehensive revisions and over five new chapters, readers are equipped with the latest research data and analyses, advancing their understanding of microbial principles. Notably, this edition provides a robust foundation for the design and analysis of omics studies, focusing on technological underpinnings and practical applications. It remains an essential resource for characterizing microbial consortia.

Methods in Biomolecular Modelling

1st Edition
August 3, 2025
Thomas W. Keal
English
eBook
9 7 8 0 4 4 3 2 2 0 4 0 1

Methods in Biomolecular Modelling, Volume Two in the series, considers modeling methods with relevance to the study of biomolecular systems, including the workhorse of classical molecular dynamics and related techniques, areas where electronic structure methods find use, the higher length scales achievable through coarse grained and mesoscale methods, and combinations of scales. Applicability of methods is then illustrated with a wide range of biomolecular modeling research topics drawn from current research. Throughout the text, practical considerations of research are emphasized, including sourcing of structural data, scalability of methods on HPC systems, and linking of computation to experiment.Part I introduces a range of modeling techniques used for biomolecular simulation, explaining the fundamental principles of each and the research areas to which they are applicable. The strengths and weaknesses of each method are outlined, along with their real-world performance on current computing resources and future trends. Part II looks at a range of application areas, with case studies illustrating the methods that can be used to investigate biomolecular systems in these areas.

The Emerging Genomic Landscape of Complex Immune-Mediated Traits

1st Edition
Volume 114
August 1, 2025
Juliana Miranda Cerqueira
English
Hardback
9 7 8 0 4 4 3 2 2 4 1 5 7
eBook
9 7 8 0 4 4 3 2 2 4 1 6 4

The Emerging Genomic Landscape of Complex Immune-Mediated Traits, Volume 114 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Unraveling the Interplay of Genetic Variants and Epigenetic Signatures in Complex traits, Crosstalk between T Cell Gene Regulation and Intestinal Epithelial Cells: Insights into Mucosal Immunity, Understanding the link between regulatory RNA regions and genomic variation with coeliac disease, Interplay Between the Host Genome, Autoimmune Disease and Infection, and Organoids and gut-on-chip as powerful tools to model the genetics of intestinal mucosal inflammation.

The Microbiome in Cancer and Autoimmunity - Part B

1st Edition
Volume 395
August 1, 2025
Manisha Singh
English
Hardback
9 7 8 0 4 4 3 3 1 7 0 8 8
eBook
9 7 8 0 4 4 3 3 1 7 0 9 5

Microbiome in Cancer and Autoimmunity - Part B, Volume 395 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. Specific chapters cover the Effect of Microbial Dysbiosis on Autoimmune-Associate... Inflammation, Gut Microbiota and Systemic Immune Responses in Cancer, The role of microbiome in gastrointestinal cancer, Cancer and Microbiome-Targeted Therapies, Autoimmune disease and Microbiome Targeted Therapies, and the Effect of Diet and Lifestyle on Microbiome Composition.

Protein Termini Part A

1st Edition
Volume 718
August 1, 2025
Thomas Arnesen
English
Hardback
9 7 8 0 4 4 3 4 1 4 8 3 1
eBook
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Protein termini represent a major route to protein regulation. From the moment the very first amino acid of a polypeptide chain exits the ribosome there is potential for steering from the cellular environment. This volume of Methods in Enzymology Modifications and Targeting of Protein Termini focuses on Protein N-termini and C-termini and their modifications which include acetylation, arginylation, myristoylation and oxidation. Also, the impact of terminal modifications is covered, in particular the impact on protein turnover and the ubiquitin E3 ligases which specifically recognize protein N-termini (N-degrons) and C-termini (C-degrons). In addition to the detailed methods and laboratory protocols, the chapters include informative overviews and reviews of the different subfields.

Pharmacoepigenetics

2nd Edition
Volume 10
July 25, 2025
Ramón Cacabelos
English
Hardback
9 7 8 0 4 4 3 1 8 7 2 2 3
eBook
9 7 8 0 4 4 3 1 8 7 2 3 0

Pharmacoepigenetics, Second Edition, Volume Ten in the Translational Epigenetics series, is a comprehensive reference on the role of epigenetics and epigenomics in drug discovery and development. Here, leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.This new edition has been fully revised to address recent advances in epigenetics, from new natural and synthetic compounds with epigenetic effects to the role of epigenetics in the pathogenesis of a growing number of complex diseases, including further cancers, cardiovascular disorders, and brain disorders. Newly identified molecular components in the functional architecture of the epigenetic machinery, as well as practical and relevant pharmacoepigenetics topics related to COVID-19 and other world health challenges are also discussed.

Immuno-oncology and Immunotherapy Part D

1st Edition
Volume 196
July 18, 2025
Lorenzo Galluzzi + 2 more
English
Hardback
9 7 8 0 4 4 3 2 9 6 1 8 5
eBook
9 7 8 0 4 4 3 2 9 6 1 9 2

Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Investigating the endothelial-immune axis in cancer, Establishing Tyro3, Axl, and Mertk Chinese Hamster Ovary (CHO) Reporter Cell Lines for Cancer Immunology and Therapeutic Applications, Amino acid analog-based labelling of the immunomodulatory cancer secretome, Human and mouse iNKT cell expansion and engineering with viral vectors, Next-generation deconvolution of the tumor microenvironment with omnideconv, and much more.Additional sections cover Comprehensive prediction of tumor neoantigens with NextNEOpi, Ex vivo profiling of organotypic tumor spheroids in 3D microfluidic culture, A flow cytometry-based assay for evaluation of T cell activation and degranulation in coculture systems, An adenosine production assay suitable for 2D and 3D cancer cell culture, Determination of lactate in the tumor interstitial fluid, Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils, Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells, and much more.

Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management

1st Edition
Volume 166
July 15, 2025
Paul B. Fisher + 4 more
English
Hardback
9 7 8 0 4 4 3 3 4 4 7 9 4
eBook
9 7 8 0 4 4 3 3 4 4 8 0 0

Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management, Volume 166 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Molecular drivers in primary brain tumor formation, Novel CSF pathways in the glioma (DIPG), Volumetric analysis in low grade gliomas and other advanced MR imaging techniques, Liquid biopsy in the diagnosis of primary brain tumors, Intraoperative imaging techniques to improve tumor detection, and much more.Additional chapters focus on Supramaximal resection in primary brain tumors, Radiotherapeutic approaches: IMRT, re-irradiation, Molecularly driven therapies in the treatment of primary brain tumors, and Changes in the immune microenvironment and immunotherapeutic strategies in the treatment of gliomas.

The Microbiome in Cancer and Autoimmunity - Part A

1st Edition
Volume 394
July 7, 2025
Manisha Singh
English
Hardback
9 7 8 0 4 4 3 3 1 7 0 6 4

Microbiome in Cancer and Autoimmunity - Part A, Volume 394 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. From deciphering the molecular mechanisms underlying microbiome-host interactions to unraveling the impact of dysbiosis on disease progression, the book provides a multifaceted analysis of the microbiome's pivotal role in cancer and autoimmunity.With contributions from leading experts in the field, this book serves as a pivotal resource for researchers, clinicians, and healthcare professionals seeking to understand and harness the therapeutic potential of the microbiome in combating cancer and autoimmune conditions.

Protein Aggregation - Part B

1st Edition
Volume 146
July 4, 2025
Rossen Donev
English
Hardback
9 7 8 0 4 4 3 4 3 0 9 6 1

Protein Aggregation - Part B, provides valuable insights into the factors driving protein aggregation, the impact on cellular function, and the role in various diseases, offering a comprehensive overview for researchers and professionals in the field of biomedicine and biochemistry.

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