Books in Biochemistry biophysics

Glucose Transporters

1st Edition
Volume 128
March 17, 2025
Gerald Litwack
English
Hardback
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eBook
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Glucose Transporters, Volume 128 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Glucose transporters and their energy homeostasis function in various organs, Molecular basis for inhibiting glucose transporters by exofacial inhibitors, Self-assembly of the insulin-responsive vesicles creates a signaling platform for the insulin action on glucose uptake, The role of lipid soluble vitamins on glucose transporter, Transport of dehydroascorbic acid by glucose transporters GLUTs, Glut-1 Inhibition in Breast Cancer Cells, Small-molecule inhibitors of glucose transporters, and more.

Advances in Clinical Chemistry

1st Edition
Volume 125
February 26, 2025
Gregory S. Makowski
English
Hardback
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eBook
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Advances in Clinical Chemistry, Volume 125, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. Content covered in this new release includes, Spotting Targets with 2D-DIGE Proteomics, Extracellular Vesicles and MicroRNAs in Cancer Progression, Brain white matter damage biomarkers, Cell-cell junctional proteins in cancer, Advances in Periodontal Healing Biomarkers, and Preeclampsia and Eclampsia: Role of Hemolytic Protozoan Iron.

TRNA-derived RNAs

1st Edition
Volume 711
February 25, 2025
Pavel Ivanov + 1 more
English
Hardback
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eBook
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tRNA-derived RNAs series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Immunotherapy: Magic Bullet to Change the Future Therapeutics

1st Edition
Volume 144
February 24, 2025
Vijay Kumar Prajapati + 1 more
English
Hardback
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eBook
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FORMTEXT Immunotherapy is emerging as a novel and reliable therapeutic technique for treating diseases such as autoimmunity, HIV/AIDS, allergy and cancers. Immunotherapy change or modulate our immune system functionalization and activate it to kill pathogen infected cells or affected cells. Development in the field of Immunology, Molecular Biology, and Pharmaceutical Sciences empower the immune system for protecting us agaist number of pathogenic infections. This volume consisit of the chapters from the different stalwarts of the field coveriing the topic such as Immunotherapy past and present, Oncolytic virus based therapy, CAR-T cell therapy, antibody engineering, adjuvant engineering etc. Chapters covered in this volume discuss the immunological translational research in the field of human cancer, parasitic and infectiouds diseases. This volume incudes the chapter describing the tools developed by scientist to engineers safe and effective antibody which can be used as powerful medicine durig human disease conditions. This volume will reflect the secret of biological sciences and technology in the field on immunology to develop safe and efficacious immune molecules based magic bullet to provide absolute cure. This volume will be helpful to the early career researchers and students working in the field of basic and applied immunological sciences.

Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis

1st Edition
Volume 211
February 18, 2025
Tanveer Ali Dar + 2 more
English
Hardback
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eBook
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Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis, Volume 112 delves into the fascinating interplay between osmolytes and intrinsically disordered proteins (IDPs), exploring their pivotal roles in cellular function and disease mechanisms. This volume brings together experts to present cutting-edge research on how osmolytes regulate functional behavior of IDPs and ensure cellular stability and adaptability under stress conditions. Specific chapters cover Functional diversity of IDPs and their structural heterogeneity: Protein structure-function continuum, Osmolytes as structure-function regulators of intrinsically disordered casein, Synergism of the effects of osmolytes and crowders on structure and function of IDPs/IDRs: The natural habitat, and more.Additional chapters delve into Osmolyte-IDP Interactions during Desiccation, Modulation of aggregation/fibrilla... propensity of IDPs by osmolytes, Osmolytes in modulating the structural and functional integrity of α-synuclein: a study based on Parkinson's disease, Regulation of the structural dynamics, aggregation, and pathogenicity of polyQ-expanded Huntingtin by osmolytes, Aggregation and inhibitory strategies of amyloid fibrillation, and much more.

ADARs

1st Edition
Volume 710
January 27, 2025
Peter Beal
English
Hardback
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eBook
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ADARs, Volume 710 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Updates in this new release include Yeast as a discovery tool for hyperactive ADARs, X-ray crystallography of ADAR-RNA complexes, Enrichment capture enhances the ability to detect A-to-I editing, Editing specificity of ADAR isoforms, Novel chemical tools for detection methods of A to I sites, En Masse Evaluation of RNA Guides (EMERGe) for ADARs, Mouse models for defining physiological functions of ADARs, Nanopore sequencing to detect A-to-I editing sites, CellREADR: An ADAR-based RNA sensor, and more.Additional sections cover Site-directed RNA editing with MS2-ADAR systems, Sequencing and Bioinformatic Tools for Accurate Assessment of A to I editing in Complete Transcriptomes, Aptazyme-directed A to I RNA editing, and Obstacles in quantifying A-to-I editing by Sanger Sequencing.

Hypothalamus

1st Edition
Volume 127
January 24, 2025
Gerald Litwack
English
Hardback
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eBook
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Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Nuclear Proteins

1st Edition
Volume 143
January 23, 2025
Rossen Donev
English
Hardback
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eBook
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Advances in Protein Chemistry and Structural Biology, Volume 143 in the series, covers reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design. Chapters in this new release include Therapeutic insight into the role of nuclear protein HNF4α in liver carcinogenesis, Structural mechanism of nucleoporins in cancer disease, Identification of nuclear matrix proteins (novel genes) in bladder cancer using Bioinformatic approaches, A comparative study of nuclear proteins of different cancers - A systematic review, Role of lamins in cellular physiology and cancer, and much more.Other chapters cover Nuclear Hormone Receptors as Drug Targets: Advancements and Future Prospects, Proteins binding to tandemly repeated DNA: familiar strangers, HMGB1, R-loops and genome stability, Nuclear tau accumulation in Alzheimer's Disease, and Histone deacetylase's (HDACs) regulates Tau function in Alzheimer's Disease.

Profiles of Drug Substances, Excipients, and Related Methodology

1st Edition
Volume 50
January 23, 2025
Abdulrahman Al-Majed
English
Hardback
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eBook
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Profiles of Drug Substances, Excipients, and Related Methodology, Volume 50 includes comprehensive profiles of four drug compounds: Sofosbuvir, Nateglinide, Linagliptin, and Dronedarone, providing comprehensive knowledge on their physical and chemical properties, synthesis and degradation pathways, analytical techniques for identification and quantification, separation methods, and pharmacology of drug substances. Finally, this volume includes a review article related to the Applications of Cyclodextrins in Pharmaceutical and Related Fields, along with a chapter on Fenamates Degradation. This information is highly valuable to professionals in the field, but having it all in one place is a great benefit to readers.The Profiles series encompasses five review articles and database compilations on various topics, including the physical profiles, analytical profiles, ADME profiles, methodologies related to the characterization, and methods of chemical synthesis of drug substances and excipients.

CRISPR-Cas-Based Genome Editing for Treating Human Diseases - Part B

1st Edition
Volume 210
January 18, 2025
Vijai Singh
English
Hardback
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eBook
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CRISPR-Cas-Based Genome Editing for Treating Human Diseases, Part B represents CRISPR-Cas systems for genome editing. Currently, CRISPR-Cas systems have been proven to be a key technology for targeted genome editing, which is acting as a simple, rapid, and cost-effective solution. Chapters in this release include Current approaches in CRISPR –Cas systems for metabolic disorders, Recent progress in CRISPR –Cas systems for CRISPR for retinal diseases, Recent progress in CRISPR –Cas systems for cataract and blindness, Advances in CRISPR –Cas systems for muscular dystrophy, Recent development in CRISPR –Cas systems for cardiac disease, Current approaches in CRISPR –Cas systems for diabetes, and much more.Additional sections cover Advances in CRISPR –Cas systems for liver disease, Advances in CRISPR –Cas systems for lung disease, Advances in CRISPR –Cas systems for kidney diseases, Current progress in CRISPR –Cas systems for rare disease, Advances in CRISPR –Cas systems for heredity disease, Recent progress in CRISPR –Cas systems for neurological disorders, and CRISPR challenges in clinical developments.

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