Books in Biochemistry biophysics

Advances in Microbial Physiology

1st Edition
Volume 86
May 23, 2025
Robert K. Poole + 1 more
English
Hardback
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eBook
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Advances in Microbial Physiology, Volume 86, the latest release in this ongoing series, continues the tradition of topical, important, cutting-edge reviews in microbiology. The editors have always strived to view microbial physiology in the broadest sense. In this volume, chapters deal with Diversity in the physiology and metabolism of chlorophototrophic bacteria, Copper homeostasis in Streptococcus and Neisseria: known knowns and unknown knowns, A Lysis Less Ordinary: The Bacterial Type 10 Secretion System, Cytochrome bd-type oxidases and environmental stressors in microbial physiology, and Multiple roles for iron in microbial physiology: bacterial oxygen sensing by heme-based sensors.

Enzymes of Polyamine Metabolism

1st Edition
Volume 715
May 19, 2025
Robert A. Casero + 1 more
English
Hardback
9 7 8 0 4 4 3 3 1 7 8 4 2
eBook
9 7 8 0 4 4 3 3 1 7 8 5 9

Enzymes of Polyamine Metabolism, Volume 715 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Convergence of MYC and the hypusine circuits in the control of metabolism, HDAC10 structure and enzymology, TR-FRET Assay for Profiling HDAC10 Inhibitors and PROTACs, Polyamine Transport Inhibitors: Methods and caveats associated with measuring polyamine uptake in mammalian cells, Evaluation of platinum drug toxicity resulting from polyamine catabolism, Measurements of acrolein adducts resulting from polyamine catabolism, Alterations in polyamine metabolism induced by the pathogen Helicobacter pylori: implications for gastric inflammation and carcinogenesis, and much more.Other sections delve into Molecular and biochemical analysis of eIF5A, Analysis of in vivo SMOX activity, Structure and role of ATP13A2 in polyamine transport, Analysis of Translational Regulation Using Polysome Profiling and Puromycin Incorporation, Targeting polyamine metabolism in an ex vivo prostatectomy model, Development and characterization of a Drosophila model of SRS, Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples, Gene replacement therapy to restore polyamine metabolism, Investigation of polyamine metabolism in bone homeostasis, Collection, preparation, and biobanking of clinical specimens for polyamine analysis, and many other topics.

Biocatalysis

1st Edition
Volume 714
May 15, 2025
Dirk Tischler
English
Hardback
9 7 8 0 4 4 3 3 1 7 8 8 0
eBook
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Biocatalysis, Volume 714 provides a wide range of themes dealing with the identification and application of biocatalysts. This includes various formats such as whole-cell or cell-free biocatalysis as well as immobilized variants. Specific chapters in this new release include Biocatalysis: How to select the proper mode of application, Documentation in biocatalysis and data handling, Mining metagenomes from extremophiles as resource for novel glycoside hydrolases for industrial applications, Functional Metaproteomics, Sequence-function relation for the prediction of enzyme properties: A case study on flavin-dependent oxidases, P450 monooxygenase in whole-cell format, and more.Additional sections cover Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells, Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species, C.necator as a model organism for CO2-based biotechnology, Cupriavidus in whole-cell biocatalysis, Whole-cell biocatalysis with Myxobacteria, Streptomyces for natural product formation: Targeted mutagenesis in PKS, Reductive Amination: Methods for cell-free and whole-cell biocatalysis, Challenges and good practices on transaminase-catalys... synthesis of optically pure amines, W-enzymes in biocatalysis: Chances and difficulties for the user, Atroposelective biocatalysis employing ADHs, Applications of alcohol oxidases, and much more.

Protien Aggregation - Part A

1st Edition
Volume 145
May 8, 2025
Rossen Donev
English
Hardback
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eBook
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Protein Aggregation, book provides valuable insights into the factors driving protein aggregation, the impact on cellular function, and the role in various diseases, offering a comprehensive overview for researchers and professionals in the field of biomedicine and biochemistry.

Cryptic Enzymes and Moonlighting Proteins

1st Edition
April 24, 2025
Helen Irving + 2 more
English
Paperback
9 7 8 0 4 4 3 1 5 7 1 9 6
eBook
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Cryptic Enzymes and Moonlighting Proteins, a new volume in the Foundations and Frontiers in Enzymology series, offers a thorough overview of cryptic enzymes and moonlighting proteins in signaling cascades. In early chapters, leading international contributors discuss evolutionary considerations for moonlighting proteins, moonlighting interactions in the extracellular matrix, eukaryotic moonlighting proteins, modulating, moonlighting kinases, moonlighting proteins in neurobiology signaling, metabolic enzymes moonlighting as RNA binding and regulatory proteins. Later, methods-driven chapters discuss practical aspects of identifying hidden moonlighting domains in proteins, computational approaches and bioinformatic tools for the identification of cryptic enzymes, establishing cryptic enzyme interactomes, and assessing contributions of moonlighting proteins to signal cascades.The book also explores recent advances in research and brings together an array of information across different fields to enable better targeting of these exciting proteins and their interactomes. With a clear focus on the role of moonlighting and cryptic enzymes in signal transduction, users will find examples of cryptic enzymes across species, as well as those in human healthy biology and pathogenesis.

Apobec Enzymes

1st Edition
Volume 713
April 21, 2025
F. Nina Papavasiliou + 1 more
English
Hardback
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eBook
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Apobec Enzymes, Volume 713 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Fluorescent shift assay for APOBECs RNA editing, Low Error Sequencing Methods to Detect APOBEC-mediated RNA editing: Circular RNAseq and Safe-Sequencing System, "Safe-Barcode" RNAseq assay for APOBECs RNA editing, DT40 cell system to characterize somatic hypermutation, CH12 cell system to assay AID activity on class switch recombination, Purification of Enzymatically Active APOBEC Proteins from an Insect Cell Expression System, and more.Additional chapters cover Defining genome-wide mutagenic impact of APOBEC3 enzymes, APOBEC-induced mutational assay in yeast, Assays for APOBEC drug discovery, Biochemical assay for the identification of APOBECs inhibitors, An In Vitro Cytidine Deaminase Assay to Monitor APOBEC activity on DNA, Profiling rare C-to-U editing events via direct RNA sequencing, Global quantification of off-target activity by base editors, and so much more.

Navigating the Complexities of SARS-CoV-2 Immunobiology

1st Edition
Volume 213
April 19, 2025
Vladimir N Uversky + 1 more
English
Hardback
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eBook
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Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

Whole Cell Biocatalysis

1st Edition
April 16, 2025
Sergio Huerta-Ochoa + 2 more
English
Paperback
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eBook
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Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.

Protein and Peptide Therapeutics

1st Edition
Volume 212
March 25, 2025
David B. Teplow
English
Hardback
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eBook
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Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

CRISPR-Cas Systems for RNA and Genome Editing

1st Edition
Volume 712
March 25, 2025
Ailong Ke + 1 more
English
Hardback
9 7 8 0 4 4 3 3 1 7 5 2 1
eBook
9 7 8 0 4 4 3 3 1 7 5 3 8

CRISPR-Cas Systems for RNA and Genome Editing, Volume 711 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Massively parallel genomic perturbations with multi-target CRISPR interrogates Cas9 activity and DNA repair at endogenous sites, Genome oligopaint via local denaturation fluorescence in situ hybridization, Biochemical reconstitution of a type I-B CRISPR-associated transposon, Visualizing the conformational landscape of CRISPR-Cas9 through kinetics-informed structural studies, and much more.Additional sections cover Analysis of metal-dependent DNA nicking activities by Cas endonucleases, Biochemically characterizing the accessory proteins and ribonucleoprotein complexes of Type IV CRISPR systems, Prime editing in bacteria with BacPE, Preparation of high-purity CRISPR-based DNA base editor RNPs, Bacterial directed evolution of CRISPR base editors, Cloning and validating systems for high throughput molecular recording, Using CRISPR-Cas13 for viral nucleic acid detection, and more.

Related subjects

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Biomembranes

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Comparative biochemistry

Enzymology

Free radicals

Lipids and lipid metabolism

Methodology techniques and instruments in biochemistry

Nucleic acids

Peptides amino acids amines amides

Physical biochemistry

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health