Biocatalysis
- 1st Edition, Volume 714 - May 22, 2025
- Editor: Dirk Tischler
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 3 1 7 8 8 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 1 7 8 9 - 7
Biocatalysis, Volume 714 provides a wide range of themes dealing with the identification and application of biocatalysts. This includes various formats such as whole-cell or cell-f… Read more
Biocatalysis, Volume 714 provides a wide range of themes dealing with the identification and application of biocatalysts. This includes various formats such as whole-cell or cell-free biocatalysis as well as immobilized variants. Specific chapters in this new release include Biocatalysis: How to select the proper mode of application, Documentation in biocatalysis and data handling, Mining metagenomes from extremophiles as resource for novel glycoside hydrolases for industrial applications, Functional Metaproteomics, Sequence-function relation for the prediction of enzyme properties: A case study on flavin-dependent oxidases, P450 monooxygenase in whole-cell format, and more.
Additional sections cover Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells, Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species, C.necator as a model organism for CO2-based biotechnology, Cupriavidus in whole-cell biocatalysis, Whole-cell biocatalysis with Myxobacteria, Streptomyces for natural product formation: Targeted mutagenesis in PKS, Reductive Amination: Methods for cell-free and whole-cell biocatalysis, Challenges and good practices on transaminase-catalysed synthesis of optically pure amines, W-enzymes in biocatalysis: Chances and difficulties for the user, Atroposelective biocatalysis employing ADHs, Applications of alcohol oxidases, and much more.
Additional sections cover Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells, Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species, C.necator as a model organism for CO2-based biotechnology, Cupriavidus in whole-cell biocatalysis, Whole-cell biocatalysis with Myxobacteria, Streptomyces for natural product formation: Targeted mutagenesis in PKS, Reductive Amination: Methods for cell-free and whole-cell biocatalysis, Challenges and good practices on transaminase-catalysed synthesis of optically pure amines, W-enzymes in biocatalysis: Chances and difficulties for the user, Atroposelective biocatalysis employing ADHs, Applications of alcohol oxidases, and much more.
- Provides guidance on how to identify, produce, describe, and apply biocatalysts, including documentation
- Includes broad perspectives on biocatalysis, including its advantages as well as its hurdles
- Presents a plethora of applications of a diverse set of enzyme-based catalysis
Enzymologists, Biotechnologists, Biocatalysts, Protein Engineers, both at academia and industries
1. Biocatalysis: How to select the proper mode of application
Dirk Tischler and Jose Munoz
2. Documentation in biocatalysis and data handling
Jürgen Pleiss
3. Mining metagenomes from extremophiles as resource for novel glycoside hydrolases for industrial applications
Jose Munoz
4. Functional Metaproteomics
Lars I. Leichert
5. Sequence-function relation for the prediction of enzyme properties: A case study on flavin-dependent oxidases
Dirk Tischler
6. P450 monooxygenase in whole-cell format
Carolin Mügge
7. Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells
Rolandas Meskys
8. Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species
Maciej Szaleniec
9. C.necator as a model organism for CO2-based biotechnology
Lars Lauterbach and Sandy Schmidt
10. Cupriavidus in whole-cell biocatalysis
Sandy Schmidt
11. Whole-cell biocatalysis with Myxobacteria
Markus Nett
12. Streptomyces for natural product formation: Targeted mutagenesis in PKS
Frank Schulz
13. Reductive Amination: Methods for cell-free and whole-cell biocatalysis
Francesco G. Mutti, Vasilis Tseliou, Matteo Damian, Josemarco Mendoza-Avila and Marco Rabuffetti
14. Challenges and good practices on transaminase-catalysed synthesis of optically pure amines
Ioannis V. Pavlidis
15. W-enzymes in biocatalysis: Chances and difficulties for the user
Peter-Leon Hagedoorn
16. Atroposelective biocatalysis employing ADHs
Gonzalo de Gonzalo
17. Applications of alcohol oxidases
Juan Mangas-Sánchez
18. Cascades with Oxidoreductases: Enzyme and Chemistry
Caroline Emilie Paul
19. In vitro biocatalysis with P450 monooxygenases
Pimchai Chaiyen
20. Construction of artificial fusion proteins for biocatalysis
Anna Christina Ngo
21. Production and engineering of chimeric UPOs
Miguel Alcalde
22. Applications of UPOs
Frank Hollmann
23. Cell free protein synthesis for biocatalysis
Katrin Rosenthal
24. Immobilization for a stable biocatalyst application
Katarzyna Szymanska, Karolina Labus, Aleksandra Lambarska and Katarzyna Czyżewska
25. Assessment of biocatalytic processes
Stephan Lütz
26. Assay development for PET degradation by biocatalysts
Álvaro Lorente-Arévalo and Aurelio Hidalgo
Dirk Tischler and Jose Munoz
2. Documentation in biocatalysis and data handling
Jürgen Pleiss
3. Mining metagenomes from extremophiles as resource for novel glycoside hydrolases for industrial applications
Jose Munoz
4. Functional Metaproteomics
Lars I. Leichert
5. Sequence-function relation for the prediction of enzyme properties: A case study on flavin-dependent oxidases
Dirk Tischler
6. P450 monooxygenase in whole-cell format
Carolin Mügge
7. Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells
Rolandas Meskys
8. Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species
Maciej Szaleniec
9. C.necator as a model organism for CO2-based biotechnology
Lars Lauterbach and Sandy Schmidt
10. Cupriavidus in whole-cell biocatalysis
Sandy Schmidt
11. Whole-cell biocatalysis with Myxobacteria
Markus Nett
12. Streptomyces for natural product formation: Targeted mutagenesis in PKS
Frank Schulz
13. Reductive Amination: Methods for cell-free and whole-cell biocatalysis
Francesco G. Mutti, Vasilis Tseliou, Matteo Damian, Josemarco Mendoza-Avila and Marco Rabuffetti
14. Challenges and good practices on transaminase-catalysed synthesis of optically pure amines
Ioannis V. Pavlidis
15. W-enzymes in biocatalysis: Chances and difficulties for the user
Peter-Leon Hagedoorn
16. Atroposelective biocatalysis employing ADHs
Gonzalo de Gonzalo
17. Applications of alcohol oxidases
Juan Mangas-Sánchez
18. Cascades with Oxidoreductases: Enzyme and Chemistry
Caroline Emilie Paul
19. In vitro biocatalysis with P450 monooxygenases
Pimchai Chaiyen
20. Construction of artificial fusion proteins for biocatalysis
Anna Christina Ngo
21. Production and engineering of chimeric UPOs
Miguel Alcalde
22. Applications of UPOs
Frank Hollmann
23. Cell free protein synthesis for biocatalysis
Katrin Rosenthal
24. Immobilization for a stable biocatalyst application
Katarzyna Szymanska, Karolina Labus, Aleksandra Lambarska and Katarzyna Czyżewska
25. Assessment of biocatalytic processes
Stephan Lütz
26. Assay development for PET degradation by biocatalysts
Álvaro Lorente-Arévalo and Aurelio Hidalgo
- Edition: 1
- Volume: 714
- Published: May 22, 2025
- Language: English
DT
Dirk Tischler
Dirk Tischler studied Applied Natural Science with focal points on Environmental Microbiology and Biotechnology as well as Environmental Analytics at TU Bergakademie Freiberg (Germany) and graduated in 2007. He continued in Freiberg with his doctoral studies on styrene monooxygenases and related enzymes and completed his dissertation with distinction in 2012. For this he was awarded with two pre-doctoral scholarships from the Deutsche Bundesstiftung Umwelt and Fulbright and he had two international research stays in Biochemistry Laboratories with Willem van Berkel at Wageningen University and George Gassner at San Francisco State University. The doctoral thesis was awarded with two prizes. He continued as a group leader in the field of industrial biotechnology with emphasis on the prediction of biocatalysts and pathways from (meta)genomes of soil bacteria, especially actinobacteria. This includes three prestigious grants for his group projects GETGEOWEB (ESF), BakSolEx (BMBF), and ChemBioCat (NRW). 2018 he became W1 Professor and was tenured in 2019 to Full Professor for Microbial Biotechnology at the Ruhr University Bochum. He focuses on the identification and application of novel biocatalysts, mostly related to redox biochemistry.
Affiliations and expertise
Ruhr-Universität Bochum, GermanyRead Biocatalysis on ScienceDirect