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Elsevier

Woodhead Publishing

  • Handbook of Offshore Helicopter Transport Safety

    Essentials of Underwater Egress and Survival
    • 1st Edition
    • Michael J. Taber
    • English
    Handbook of Offshore Helicopter Transport Safety: Essentials of Underwater Egress and Survival provides a comprehensive look at the issues and concerns facing offshore helicopter transport. The book offers guidance for offshore helicopter operators, survival instructors, and the global offshore workforce, including discussions of safety management systems, safety briefings, survival equipment, underwater egress training, water impact/ditching statistics, and search and rescue. Each area of interest details pertinent information spanning approximately 30 years of offshore operations. Early sections discuss helicopter transport safety, safety regulations, and standards, while subsequent chapters cover Helicopter Underwater Escape Training (HUET) programs and their development and training, followed by final chapters on the effects of HUET, Emergency Breathing Systems (EBS), and Helicopter Transportation Suit (HTS).

  • A Practical Guide to Rational Drug Design

    • 1st Edition
    • Sun Hongmao
    • English
    This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors’ active compounds or from natural ligands of the targets; how to springboard from competitors’ SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes.

  • Concepts and Models for Drug Permeability Studies

    Cell and Tissue based In Vitro Culture Models
    • 1st Edition
    • Bruno Sarmento
    • English
    This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

  • Marine Applications of Advanced Fibre-reinforced Composites

    • 1st Edition
    • Jasper Graham-Jones + 1 more
    • English
    The marine environment presents significant challenges for materials due to the potential for corrosion by salt water, extreme pressures when deeply submerged and high stresses arising from variable weather. Well-designed fibre-reinforced composites can perform effectively in the marine environment and are lightweight alternatives to metal components and more durable than wood. Marine Applications of Advanced Fibre-Reinforced Composites examines the technology, application and environmental considerations in choosing a fibre-reinforced composite system for use in marine structures. This book is divided into two parts. The chapters in Part One explore the manufacture, mechanical behavior and structural performance of marine composites, and also look at the testing of these composites and end of life environmental considerations. The chapters in Part Two then investigate the applications of marine composites, specifically for renewable energy devices, offshore oil and gas applications, rigging and sails. Underwater repair of marine composites is also reviewed.

  • Biomineralization and Biomaterials

    Fundamentals and Applications
    • 1st Edition
    • Conrado Aparicio + 1 more
    • English
    Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance.

  • Compendium of Hydrogen Energy

    Hydrogen Energy Conversion
    • 1st Edition
    • Frano Barbir + 2 more
    • English
    Compendium of Hydrogen Energy: Hydrogen Energy Conversion, Volume Three is the third part of a four volume series and focuses on the methods of converting stored hydrogen into useful energy. The other three volumes focus on hydrogen production and purification; hydrogen storage and transmission; and hydrogen use, safety, and the hydrogen economy, respectively. Many experts believe that, in time, the hydrogen economy will replace the fossil fuel economy as the primary source of energy. Once hydrogen has been produced and stored, it can then be converted via fuel cells or internal combustion engines into useful energy. This volume highlights how different fuel cells and hydrogen-fueled combustion engines and turbines work. The first part of the volume investigates various types of hydrogen fuel cells, including solid oxide, molten carbonate, and proton exchange membrane. The second part looks at hydrogen combustion energy, and the final section explores the use of metal hydrides in hydrogen energy conversion.

  • A Complete Course in Canning and Related Processes

    • 14th Edition
    • Susan Featherstone
    • English
    A complete course in canning is firmly established as a unique and essential guide to canning and related processes. Professionals in the canning industry and students have benefited from successive editions of the book for over 100 years. This major new edition continues that reputation, with extensively revised and expanded coverage. The three-title set is designed to cover all planning, processing, storage and quality control phases undertaken by the canning industry in a detailed, yet accessible fashion. Major changes for the new edition include new chapters on regulation and labelling that contrast the situation in different regions worldwide, updated information on containers for canned foods and new information on validation and optimization of canning processes, among many others.

  • Bird Strike

    An Experimental, Theoretical and Numerical Investigation
    • 1st Edition
    • Reza Hedayati + 1 more
    • English
    Bird strikes are one of the most dangerous threats to civil and military flight safety: between 1960 and 2014, they were responsible for the destruction of approximately 150 civil aircraft and the deaths of 271 people. Bird Strike presents a summary of the damage imposed on the aviation industries by their avian counterparts. This book first presents and analyzes the statistics obtained from bird strike databases and offers various methods for minimizing the overall probability of bird-strike events. The next chapters explore how to analyze the ability of aero-engine critical structures to withstand bird-strike events by implementing reliable experimental, theoretical, and numerical methods. Finally, the book investigates the impact of bird strikes on different components of aircrafts, such as the metal fuselage, composite fuselage, engines, wings, and tail, and proposes two new bird models, with explanations of their use.

  • A Complete Course in Canning and Related Processes

    Volume 3 Processing Procedures for Canned Food Products
    • 14th Edition
    • Susan Featherstone
    • English
    A Complete Course in Canning and Related Processes: Volume 3, Processing Procedures for Canned Food Products, Fourteenth Edition provides a complete course in canning and is an essential guide to canning and related processes. Professionals and students in the canning industry have benefited from successive editions of the book for over 100 years. This major new edition continues that reputation, with extensively revised and expanded coverage. The book's three-title set is designed to cover all planning, processing, storage, and quality control phases undertaken by the canning industry in a detailed, yet accessible fashion. Major changes for the new edition include new chapters on regulation and labeling that contrast the situation in different regions worldwide, updated information on containers for canned foods, and new information on validation and optimization of canning processes, among many other topics.

  • Modeling Neuropsychiatric Disorders in Laboratory Animals

    • 1st Edition
    • Kurt Leroy Hoffman
    • English
    Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research.

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